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Journal of Nephrology
Published in: Journal of Nephrology 4/2019

01-08-2019 | Review

Renal intraparenchymal resistive index: the ultrasonographic answer to many clinical questions

Authors: Pierpaolo Di Nicolò, Antonio Granata

Published in: Journal of Nephrology | Issue 4/2019

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Abstract

The use of renal resistive indices (RRIs) for the study of renal microcirculation has in the past been proposed for the identification of renal organ damage or even to specifically identify injury to some areas of the renal parenchyma. Nevertheless, according to the most recent evidences from literature this organ-based conception of RRIs has been proven to be partial and unable to explain the RRIs variations in clinical settings of sepsis or combined organ failure of primitively extrarenal origin or, more generally, the deep connection between RRIs and hemodynamic factors such as compliance and pulsatility of the large vessels. The aim of this review is to explain the physiopathological basis of RRIs determination and the most common interpretative errors in their analysis. Moreover, through a comprehensive vision of these Doppler indices, the traditional and emerging clinical application fields for RRIs are discussed.
Literature
1.
Di Nicolò P, Granata A (2017) Renal Resistive Index: not only kidney. Clin Exp Nephrol 21(3):359–366CrossRefPubMed
2.
3.
Hitsumoto T (2017) Relationship between hemorheology assessed using microchannel array flow analyzer and kidney function in hypertensive patients. Cardiol Res 8(4):147–153CrossRefPubMedPubMedCentral
4.
Linde T, Sandhagen B, Hägg A, Mörlin C, Wikström B (1993) Danielson BG Blood viscosity and peripheral vascular resistance in patients with untreated essential hypertension. J Hypertens 11(7):731–736CrossRefPubMed
5.
O’Neill WC (2014) Renal resistive index: a case of mistaken identity. Hypertension 64(5):915–917CrossRefPubMed
6.
Bude RO, Rubin JM (1999) Relationship between the resistive index and vascular compliance and resistance. Radiology 211:411–417CrossRefPubMed
7.
Tublin ME, Tessler FN, Murphy ME (1999) Correlation between renal vascular resistance, pulse pressure, and the resistive index in isolated perfused rabbit kidneys. Radiology 213:258–264CrossRefPubMed
8.
Hashimoto J, Ito S (2011) Central pulse pressure and aortic stiffness determine renal hemodynamics: pathophysiological implication for microalbuminuria in hypertension. Hypertension 58(5):839–846CrossRefPubMed
9.
O’Rourke MF, Safar ME (2005) Relationship between aortic stiffening and microvascular disease in brain and kidney: cause and logic of therapy. Hypertension 46(1):200–204CrossRefPubMed
10.
Ikee R, Kobayashi S, Hemmi N, Imakiire T, Kikuchi Y, Moriya H, Suzuki S, Miura S (2005) Correlation between the resistive index by Doppler ultrasound and kidney function and histology. Am J Kidney Dis 46:603–609CrossRefPubMed
11.
Mostbeck GH, Gossinger HD, Mallek R, Siostrzonek P, Schneider B, Tscholakoff D (1990) Effect of heart rate on Doppler measurements of resistive index in renal arteries. Radiology 175:511–513CrossRefPubMed
12.
Kuznetsova T, Cauwenberghs N, Knez J, Thijs L, Liu YP, Gu YM, Staessen JA (2015) Doppler indexes of left ventricular systolic and diastolic flow and central pulse pressure in relation to renal resistive index. Am J Hypertens 28(4):535–545CrossRefPubMed
13.
14.
Platt J, Ellis J, Rubin J, DiPietro MA, Sedman AB (1990) Intrarenal arterial Doppler sonography in patients with nonobstructive renal disease: correlation of resistive index with biopsy findings. AJR 154:1223–1227CrossRefPubMed
15.
Mostbeck G, Kain R, Mallek R et al (1991) Duplex Doppler sonography in renal parenchymal disease; histopathologic correlation. J Ultrasound Med 10:189–194CrossRefPubMed
16.
Ohta Y, Fujii K, Arima H, Matsumura K, Tsuchihashi T, Tokumoto M, Tsuruya K, Kanai H, Iwase M, Hirakata H, Iida M (2005) Increased renal resistive index in atherosclerosis and diabetic nephropathy assessed by Doppler sonography. J Hypertens 23:1905–1911CrossRefPubMed
17.
Calabia J, Torguet P, Garcia I, Martin N, Mate G, Marin A, Molina C, Valles M (2014) The relationship between renal resistive index, arterial stiffness, and atherosclerotic burden: the link between macrocirculation and microcirculation. J Clin Hypertens (Greenwich) 16(3):186–191CrossRef
18.
Pontremoli R, Viazzi F, Martinoli C, Ravera M, Nicolella C, Berruti V, Leoncini G, Ruello N, Zagami P, Bezante GP, Derchi LE, Deferrari G (1999) Increased renal resistive index in patients with essential hypertension: a marker of target organ damage. Nephrol Dial Transpl 14(2):360–365CrossRef
19.
Stefan G, Capusa C, Stancu S, Petrescu L, Nedelcu ED, Andreiana I, Mircescu G (2014) Abdominal aortic calcification and renal resistive index in patients with chronic kidney disease: is there a connection? J Nephrol 27(2):173–179CrossRefPubMed
20.
Pruijm M, Lu Y, Megdiche F, Piskunowicz M, Milani B, Stuber M, Bachtler M, Vogt B, Burnier M (2017) Pasch A Serum calcification propensity is associated with renal tissue oxygenation and resistive index in patients with arterial hypertension or chronic kidney disease. J Hypertens 35(10):2044–2052CrossRefPubMed
21.
Nosadini R, Velussi M, Brocco E, Abaterusso C, Carraro A, Piarulli F, Morgia G, Satta A, Faedda R, Abhyankar A, Luthman H, Tonolo G (2006) Increased renal arterial resistance predicts the course of renal function in type 2 diabetes with microalbuminuria. Diabetes 55:234–239CrossRefPubMed
22.
Okura T, Kurata M, Irita J, Enomoto D, Jotoku M, Nagao T, Koresawa M, Kojima S, Hamano Y, Mashiba S, Miyoshi K, Higaki J (2010) Renal resistance index is a marker of future renal dysfunction in patients with essential hypertension. J Nephrol 23:175–180PubMed
23.
Tsioufis C, Andrikou I, Pruijm M, Ponte B, Sarafidis P, Koureas A, Tousoulis D, Agabiti-Rosei E, Mancia G, Burnier MJ (2018) Should renal color Doppler ultrasonography be a routine test in newly diagnosed hypertensive patient? Hypertens 36(1):16–22CrossRef
24.
Buckley AR, Cooperberg PL, Reeve CE, Magil AB (1987) The distinction between acute renal transplant rejection and cyclosporine nephrotoxicity: value of duplex sonography. AJR Am J Roentgenol 149(3):521–525CrossRefPubMed
25.
Genkins SM, Sanfilippo FP, Carroll BA (1989) Duplex Doppler sonography of renal transplants: lack of sensitivity and specificity in establishing pathologic diagnosis. AJR Am J Roentgenol 152(3):535–539CrossRefPubMed
26.
Perrella RR, Duerinckx AJ, Tessler FN, Danovitch GM, Wilkinson A, Gonzalez S, Cohen AH, Grant EG (1990) Evaluation of renal transplant dysfunction by duplex Doppler sonography: a prospective study and review of the literature. Am J Kidney Dis 15(6):544–550CrossRefPubMed
27.
Heine GH, Gerhart MK, Ulrich C, Ko ¨hler H, Girndt M (2005) Renal Doppler resistance indices are associated with systemic atherosclerosis in kidney transplant recipients. Kidney Int 68:878–885CrossRefPubMed
28.
Seiler S, Colbus SM, Lucisano G, Rogacev KS, Gerhart MK, Ziegler M, Fliser D, Heine GH (2012) Ultrasound renal resistive index is not an organ-specific predictor of allograft outcome. Nephrol Dial Transpl 27(8):3315–3320CrossRef
29.
Naesens M, Heylen L, Lerut E, Claes K, De Wever L, Claus F et al (2013) Intrarenal resistive index after renal transplantation. N Engl J Med 369:1797–1806CrossRefPubMed
30.
Kolonko A, Szotowska M, Kuczera P, Chudek J, Wiecek A (2013) Extra renal factors influencing resistance index in stable kidney transplant recipients. Transplantation 96(4):406–412 (August 27th) CrossRefPubMed
31.
Yoo MG, Jung DC, Oh YT, Park SY, Han K (2017) Usefulness of multiparametric ultrasound for evaluating structural abnormality of transplanted kidney: can we predict histologic abnormality on renal biopsy in advance? AJR Am J Roentgenol 209(3):W139–W144CrossRefPubMed
32.
Cano H, Castañeda DA, Patiño N, Pérez HC, Sánchez M, Lozano E, Pérez MC (2014) Resistance index measured by Doppler ultrasound as a predictor of graft function after kidney transplantation. Transpl Proc 46(9):2972–2974CrossRef
33.
Radermacher J, Mengel M, Ellis S, Stuht S, Hiss M, Schwarz A, Eisenberger U, Burg M, Luft FC, Gwinner W, Haller H (2003) The renal arterial resistance index and renal allograft survival. N Engl J Med 349(2):115–124CrossRefPubMed
34.
Kolonko A, Chudek J, Więcek A (2015) Initial kidney graft resistance index and the long-term cardiovascular mortality in transplanted patients: a paired grafts analysis. Nephrol Dial Transpl 30:1218–1224CrossRef
35.
Parolini C, Noce A, Staffolani E, Giarrizzo GF, Costanzi S, Splendiani G (2009) Renal resistive index and long-term outcome in chronic nephropathies. Radiology 252:888–896CrossRefPubMed
36.
Sugiura T, Wada A (2009) Resistive index predicts renal prognosis in chronic kidney disease. Nephrol Dial Transpl 24:2780–2785CrossRef
37.
Sugiura T, Wada A (2011) Resistive index predicts renal prognosis in chronic kidney disease: results of a 4-year follow-up. Clin Exp Nephrol 15(1):114–120CrossRefPubMed
38.
Radermacher J, Chavan A, Bleck J, Vitzthum A, Stoess B, Gebel MJ, Galanski M, Koch KM, Haller H (2001) Use of Doppler ultrasonography to predict the outcome of therapy for renal-artery stenosis. N Engl J Med 344(6):410–417CrossRefPubMed
39.
Bruno RM, Daghini E, Versari D, Sgrò M, Sanna M, Venturini L, Romanini C, Di Paco I, Sudano I, Cioni R, Lerman LO, Ghiadoni L, Taddei S, Pinto S (2014) Predictive role of renal resistive index for clinical outcome after revascularization in hypertensive patients with atherosclerotic renal artery stenosis: a monocentric observational study. Cardiovasc Ultrasound 12:9CrossRefPubMedPubMedCentral
40.
Toledo C, Thomas G, Schold JD, Arrigain S, Gornik HL, Nally JV, Navaneethan SD (2015) Renal resistive index and mortality in chronic kidney disease. Hypertension 66(2):382–388CrossRefPubMedPubMedCentral
41.
Kim JH, Lee SM, Son YK, Kim SE, An WS (2017) Resistive index as a predictor of renal progression in patients with moderate renal dysfunction regardless of angiotensin converting enzyme inhibitor or angiotensin receptor antagonist medication. Kidney Res Clin Pract 36(1):58–67CrossRefPubMedPubMedCentral
42.
Radermacher J, Ellis S, Haller H (2002) Renal resistance index and progression of renal disease. Hypertension 39(2 Pt 2):699–703CrossRefPubMed
43.
Afsar B, Elsurer R (2012) Comparison of renal resistive index among patients with Type 2 diabetes with different levels of creatinine clearance and urinary albumin excretion. Diabetes Med 29:1043–1046CrossRef
44.
Hamano K, Nitta A, Ohtake T, Kobayashi S (2008) Associations of renal vascular resistance with albuminuria and other macroangiopathy in type 2 diabetic patients. Diabetes Care 31:1853–1857CrossRefPubMedPubMedCentral
45.
Bruno RM, Daghini E, Landini L, Versari D, Salvati A, Santini E et al (2011) Dynamic evaluation of renal resistive index in normoalbuminuric patients with newly diagnosed hypertension or type 2 diabetes. Diabetologia 54:2430–2439CrossRefPubMed
46.
Masulli M, Mancini M, Liuzzi R, Daniele S, Mainenti PP, Vergara E et al (2009) Measurement of the intrarenal arterial resistance index for the identification and prediction of diabetic nephropathy. Nutr Metab Cardiovasc Dis 19:358–364CrossRefPubMed
47.
Youssef DM, Fawzy FM (2012) Value of renal resistive index as an early marker of diabetic nephropathy in children with type-1 diabetes mellitus. Saudi J Kidney Dis Transpl 23(5):985–992CrossRefPubMed
48.
El Ghaffar S, El Kaffas K, Hegazy R, Mostafa M (2010) Renal Doppler indices in diabetic children with insulin resistance syndrome. Pediatr Diabetes 11:479–486CrossRef
49.
Opdenakker L, Oyen R, Vervloessem I, Goethuys H, Baert AL, Baert LV et al (1998) Acute obstruction of the renal collecting system: the intrarenal resistive index is a useful yet time-dependent parameter for diagnosis. Eur Radiol 8:1429–1432CrossRefPubMed
50.
Granata A, Andrulli S, Bigi MQ, Pozzoni P, Fiorini F, Logias F, Figuera M, Basile A, Fiore CE (2009) Predictive role of duplex Doppler ultrasonography in the diagnosis of acute renal obstruction in patients with unilateral renal colic. Clin Nephrol 71(6):680–686CrossRefPubMed
51.
Juan YS, Huang CH, Wang CJ, Chou YH, Chuang SM, Li CC, Shen JT, Wu WJ (2008) Predictive role of renal resistance indices in the extracorporeal shock-wave lithotripsy outcome of ureteral stones. Scand J Urol Nephrol 42(4):364–368CrossRefPubMed
52.
Kiliç S, Altinok MT, Ipek D, Beytur A, Baydinç YC, Güneş G (2005) Color Doppler sonography examination of partially obstructed kidneys associated with ureteropelvic junction stone before and after percutaneous nephrolithotripsy: preliminary report. Int J Urol 12(5):429–435CrossRefPubMed
53.
Shokeir AA, Shoma AM, Abubieh EA, Nasser MA, Eassa W, El-Asmy A (2002) Recoverability of renal function after relief of acute complete ureteral obstruction: clinical prospective study of the role of renal resistive index. Urology 59(4):506–510CrossRefPubMed
54.
Platt JF, Ellis JH, Rubin JM, Merion RM, Lucey MR (1994) Renal duplex Doppler ultrasonography: a noninvasive predictor of kidney dysfunction and hepato-renal failure in liver disease. Hepatology 20:362–369CrossRefPubMed
55.
Celebi H, Dönder E, Celiker H (1997) Renal blood flow detection with Doppler ultrasonography in patients with hepatic cirrhosis. Arch Intern Med 157(5):564–566CrossRefPubMed
56.
Ćulafić D, Štulić M, Obrenović R, Miletić D, Mijač D, Stojković M, Jovanović M, Ćulafić M (2014) Role of cystatin C and renal resistive index in assessment of renal function in patients with liver cirrhosis. World J Gastroenterol 20(21):6573–6579CrossRefPubMedPubMedCentral
57.
Rivolta R, Maggi A, Cazzaniga M, Castagnone D, Panzeri A, Solenghi D, Lorenzano E, di Palo FQ, Salerno F (1998) Reduction of renal cortical blood flow assessed by Doppler in cirrhotic patients with refractory ascites. Hepatology 28(5):1235–1240CrossRefPubMed
58.
Wang Y, Liu LP, Bai WY, Wen SB, Dan HJ, Luan YY, Zeng MX, Hu BJ (2011) Renal haemodynamics in patients with liver cirrhosis assessed by colour ultrasonography. Int Med Res 39(1):249–255CrossRef
59.
Solís-Muñoz PA, Willars C, Wendon J, Auzinger G, Heneghan MA, De la Flor-Robledo M, Solís-Herruzo JA (2018) Interlobar artery resistive index predicts acute-on-chronic liver failure syndrome in cirrhotic patients with acute decompensation. Ultraschall Med 39(1):39–47CrossRefPubMed
60.
Darmon M, Schortgen F, Leon R, Moutereau S, Mayaux J, Di Marco F, Devaquet J, Brun-Buisson C, Brochard L (2009) Impact of mild hypoxemia on renal function and renal resistive index during mechanical ventilation. Intensive Care Med 35(6):1031–1038CrossRefPubMed
61.
Ennezat PV, Maréchaux S, Six-Carpentier M, Pinçon C, Sediri I, Delsart P, Gras M, Mounier-Véhier C, Gautier C, Montaigne D, Jude B, Asseman P, Le Jemtel TH (2011) Renal resistance index and its prognostic significance in patients with heart failure with preserved ejection fraction. Nephrol Dial Transpl 26(12):3908–3913CrossRef
62.
Ciccone MM, Iacoviello M, Gesualdo L, Puzzovivo A, Antoncecchi V, Doronzo A, Monitillo F, Citarelli G, Paradies V, Favale S (2014) The renal arterial resistance index: a marker of renal function with an independent and incremental role in predicting heart failure progression. Eur J Heart Fail 16(2):210–216CrossRefPubMed
63.
64.
Song J, Wu W, He Y, Lin S, Zhu D, Zhong M (2018) Value of the combination of renal resistance index and central venous pressure in the early prediction of sepsis-induced acute kidney injury. J Crit Care 45:204–208CrossRefPubMed
65.
Lerolle N, Guérot E, Faisy C, Bornstain C, Diehl JL, Fagon JY (2006) Renal failure in septic shock: predictive value of Doppler-based renal arterial resistive index. Intensive Care Med 32(10):1553–1559CrossRefPubMed
66.
Darmon M, Schortgen F, Vargas F, Liazydi A, Schlemmer B, Brun-Buisson C, Brochard L (2011) Diagnostic accuracy of Doppler renal resistive index for reversibility of acute kidney injury in critically ill patients. Intensive Care Med 37(1):68–76CrossRefPubMed
67.
Corradi F, Brusasco C, Vezzani A, Palermo S, Altomonte F, Moscatelli P, Pelosi P (2011) Hemorrhagic shock in polytrauma patients: early detection with renal Doppler resistive index measurements. Radiology 260(1):112–118CrossRefPubMed
68.
Corradi F, Brusasco C, Garlaschi A, Santori G, Vezzani A, Moscatelli P, Pelosi P (2012) Splenic Doppler resistive index for early detection of occult hemorrhagic shock after polytrauma in adult patients. Shock 38(5):466–473CrossRefPubMed
69.
Wybraniec MT, Bożentowicz-Wikarek M, Chudek J, Mizia-Stec K (2017) Pre-procedural renal resistive index accurately predicts contrast-induced acute kidney injury in patients with preserved renal function submitted to coronary angiography. Int J Cardiovasc Imaging 33(5):595–604CrossRefPubMed
70.
Afsar B, Elsurer R (2017) Increased renal resistive index in type 2 diabetes: clinical relevance, mechanisms and future directions. Diabetes Metab Syndr 11(4):291–296CrossRefPubMed
71.
Solini A, Giannini L, Seghieri M, Vitolo E, Taddei S, Ghiadoni L, Bruno RM (2017) Dapagliflozin acutely improves endothelial dysfunction, reduces aortic stiffness and renal resistive index in type 2 diabetic patients: a pilot study. Cardiovasc Diabetol 16(1):138CrossRefPubMedPubMedCentral
72.
Rawashdeh YF, Hørlyck A, Mortensen J, Hvistendahl JJ, Frokiaer J, Djurhuus JC (2003) Resistive index: an experimental study of acute complete unilateral ureteral obstruction. Invest Radiol 38(3):153–158PubMed
73.
Bateman GA, Cuganesan R (2002) Renal vein Doppler sonography of obstructive uropathy. AJR Am J Roentgenol 178(4):921–925CrossRefPubMed
74.
Webb JAW (2000) Ultrasonography and Doppler studies in the diagnosis of renal obstruction. BJU Int 86(Suppl 1):25–32PubMed
75.
Onur MR, Cubuk M, Andic C, Kartal M, Arslan G (2007) Role of resistive index in renal colic. Urol Res 35(6):307–312CrossRefPubMed
76.
Bertolotto M, Quaia E, Gasparini C, Calderan L, Pozzi Mucelli R (2003) Resistive index in patients with renal colic: differences after medical treatment with indomethacin and ketorolac. Radiol Med 106(4):370–375PubMed
77.
Andrew BY, Cherry AD, Hauck JN, Nicoara A, Maxwell CD, Konoske RM, Thompson A, Kartha LD, Swaminathan M, Stafford-Smith M (2018) The association of aortic valve pathology with renal resistive index as a kidney injury biomarker. Ann Thorac Surg 106(1):107–114CrossRefPubMedPubMedCentral
78.
Boddi M, Natucci F, Ciani E (2015) The internist and the renal resistive index: truths and doubts. Intern Emerg Med 10(8):893–905CrossRefPubMed
79.
Burnett JC Jr, Knox FG (1980) Renal interstitial pressure and sodium excretion during renal vein constriction. Am J Physiol 238(4):F279–F282PubMed
80.
Di Nicolò P (2018) The dark side of the kidney in cardio-renal syndrome: renal venous hypertension and congestive kidney failure. Heart Fail Rev 23(2):291–302CrossRefPubMed
81.
Nijst P, Martens P, Dupont M, Tang WHW, Mullens W (2017) Intrarenal flow alterations during transition from euvolemia to intravascular volume expansion in heart failure patients. JACC Heart Fail 5(9):672–681CrossRefPubMed
82.
Berger EY, Galdston M, Horwitz (1949) SA effect of anoxic anoxia on human kidney. Clin Invest 28:648CrossRef
83.
Howes TQ, Deane CR, Levin GE, Baudouin SV, Moxham J (1995) The effects of oxygen and dopamine on renal and aortic blood flow in chronic obstructive pulmonary disease with hypoxemia and hypercapnia. Am J Respir Crit Care Med 151(2 Pt 1):378–383CrossRefPubMed
84.
85.
Sharkey RA1, Mulloy EM, O’Neill SJ (1998) Acute effects of hypoxaemia, hyperoxaemia and hypercapnia on renal blood flow in normal and renal transplant subjects. Eur Respir J 12(3):653–657CrossRefPubMed
86.
Baudouin SV, Bott J, Ward A, Deane C, Moxham J (1992) Short term effect of oxygen on renal haemodynamics in patients with hypoxaemic chronic obstructive airways disease. Thorax 47(7):550–554CrossRefPubMedPubMedCentral
87.
Møller S, Henriksen JH, Bendtsen F (2014) Extrahepatic complications to cirrhosis and portal hypertension: haemodynamic and homeostatic aspects. World J Gastroenterol 20(42):15499–15517CrossRefPubMedPubMedCentral
88.
Ninet S, Schnell D, Dewitte A, Zeni F, Meziani F, Darmon M (2015) Doppler-based renal resistive index for prediction of renal dysfunction reversibility: a systematic review and meta-analysis. J Crit Care 30(3):629–635CrossRefPubMed
89.
Deruddre S, Cheisson G, Mazoit JX, Vicaut E, Benhamou D, Duranteau J (2007) Renal arterial resistance in septic shock: effects of increasing mean arterial pressure with norepinephrine on the renal resistive index assessed with Doppler ultrasonography. Intensive Care Med 33(9):1557–1562CrossRefPubMed
90.
Dewitte A, Coquin J, Meyssignac B, Joannès-Boyau O, Fleureau C, Roze H, Ripoche J, Janvier G, Combe C, Ouattara A (2012) Doppler resistive index to reflect regulation of renal vascular tone during sepsis and acute kidney injury. Crit Care 16(5):R165CrossRefPubMedPubMedCentral
91.
Schnell D, Camous L, Guyomarc’h S, Duranteau J, Canet E, Gery P, Dumenil AS, Zeni F, Azoulay E, Darmon M (2013) Renal perfusion assessment by renal Doppler during fluid challenge in sepsis. Crit Care Med 41(5):1214–1220CrossRefPubMed
92.
Lahmer T, Rasch S, Schnappauf C, Schmid RM, Huber W (2016) Influence of volume administration on Doppler-based renal resistive index, renal hemodynamics and renal function in medical intensive care unit patients with septic-induced acute kidney injury: a pilot study. Int Urol N 48(8):1327–34CrossRef
93.
Krug EG, Sharma GK, Lozano R (2000) The global burden of injuries. Am J Public Health 90:523Y526
94.
Spahn DR, Cerny V, Coats TJ, Duranteau J, Fernàndez-Mondejar E, Gordini G, Stahel PF, Hunt BJ, Komadina R, Neugebauer E, Ozier Y, Riddez L, Schultz A, Vincent JL, Rossaint R (2007) Task Force for advanced bleeding care in trauma. Management of bleeding following major trauma: a European guideline. Crit Care 11(1):R17CrossRefPubMedPubMedCentral
95.
Grun OS, Herath E, Weihrauch A, Flugge F, Rogacev KS, Fliser D, Heine GH (2012) Does the measurement of the difference of resistive indexes in spleen and kidney allow a selective assessment of chronic kidney injury? Radiology 264:894–902CrossRefPubMed
96.
Robert R, Vinet M, Jamet A, Coudroy R (2017) Effect of non-invasive remote ischemic preconditioning on intra-renal perfusion in volunteers. J Nephrol 30(3):393–395CrossRefPubMed
97.
Metadata
Title
Renal intraparenchymal resistive index: the ultrasonographic answer to many clinical questions
Authors
Pierpaolo Di Nicolò
Antonio Granata
Publication date
01-08-2019
Publisher
Springer International Publishing
Published in
Journal of Nephrology / Issue 4/2019
Print ISSN: 1121-8428
Electronic ISSN: 1724-6059
DOI
https://doi.org/10.1007/s40620-018-00567-x

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