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Published in: Current Cardiovascular Imaging Reports 4/2020

01-04-2020 | Edema | Cardiac Magnetic Resonance (E Nagel and V Puntmann, Section Editors)

CMR in Hypertrophic Cardiac Conditions—an Update

Authors: Michalis Kolentinis, Viviana Maestrini, Eleftherios Vidalakis, Sara Cimino, Luca Arcari

Published in: Current Cardiovascular Imaging Reports | Issue 4/2020

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Abstract

Purpose of Review

Myocardial left ventricular (LV) hypertrophy (LVH) is a common phenotype associated to increased morbidity and mortality. Beyond an accurate LV mass quantification, cardiovascular magnetic resonance (CMR) can also provide tissue characterization, perfusion, and deformation assessments. Aim of the present review is to discuss recent advances in CMR imaging of LVH.

Recent Findings

T1 and T2 mapping techniques expanded the ability of CMR in phenotyping LVH, underscoring the pathogenic significance of interstitial fibrosis and edema in hypertrophic conditions. Perfusion and deformation assessments revealed dysfunctional correlates not uncommonly associated to LVH. Late gadolinium enhancement (LGE) highlighted the role of replacement fibrosis as a marker of advanced disease. Finally, the prognostic relevance of both interstitial and replacement fibrosis has been demonstrated in several LVH conditions.

Summary

CMR is an efficient tool for differential diagnosis of LVH phenotypes. Furthermore, it can often provide prognostic information, potentially guiding treatment and improving clinical management.
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Metadata
Title
CMR in Hypertrophic Cardiac Conditions—an Update
Authors
Michalis Kolentinis
Viviana Maestrini
Eleftherios Vidalakis
Sara Cimino
Luca Arcari
Publication date
01-04-2020
Publisher
Springer US
Published in
Current Cardiovascular Imaging Reports / Issue 4/2020
Print ISSN: 1941-9066
Electronic ISSN: 1941-9074
DOI
https://doi.org/10.1007/s12410-020-9533-1