Skip to main content
Key Specialties
Cardiology Diabetology Endocrinology Gastroenterology Geriatrics and Gerontology Gynecology and Obstetrics Hematology Infectious Disease Internal Medicine Nephrology Neurology Oncology Pediatrics Respiratory Medicine Rheumatology Surgery
Congress Coverage
2024 ACC Congress 2023 ESMO Congress 2023 EASD Congress 2023 ERS Congress 2023 ESC Congress
Clinical Collections
Advances in Alzheimer’s

Keynote webinar | Spotlight on medication adherence

LIVE: Thursday 27th June 2024, 18:00-19:30 (CEST)
Join our expert panel to discover why you need to understand the drivers of non-adherence in your patients, and how you can optimize medication adherence in your clinics to drastically improve patient outcomes.
ADVANCED SEARCH
Log in
Top
Journal of Nuclear Cardiology
Published in: Journal of Nuclear Cardiology 4/2020

01-08-2020 | Left Bundle Branch Block | Editorial

Refining the role of gated SPECT for predicting clinical response to cardiac resynchronization therapy: Are we using the right tool at the wrong time?

Author: Dennis A. Calnon, MD, MASNC

Published in: Journal of Nuclear Cardiology | Issue 4/2020

Login to get access

Excerpt

The accurate prediction of clinical response to cardiac resynchronization (CRT) remains challenging, despite much work in this area. International guidelines for the use of CRT are currently based solely on the severity of heart failure despite optimal medical therapy, reduced left ventricular ejection fraction (LVEF), electrical dyssynchrony (QRS duration), and atrial rhythm.1 However, as many as 30-40% of patients who meet patient selection criteria fail to derive clinical benefit following CRT.2 …
Literature
1.
Normand C, Linde C, Singh J, Dickstein K. Indications for cardiac resynchronization therapy: A comparison of the major international guidelines. J Am Coll Cardiol HF 2018;6:308-16.
2.
Abraham WT, Fisher WG, Smith AL, et al. Cardiac resynchronization in chronic heart failure. N Engl J Med 2002;346:1845-53.CrossRef
3.
Bleeker G, Mollema SA, Holman ER, et al. Left ventricular resynchronization is mandatory for response to cardiac resynchronization therapy: Analysis in patients with echocardiographic evidence of left ventricular dyssynchrony at baseline. Circulation 2007;116:1440-8.CrossRef
4.
Chen J, Garcia EV, Bax JJ, et al. SPECT myocardial perfusion imaging for the assessment of left ventricular mechanical dyssynchrony. J Nucl Cardiol 2011;18:685-94.CrossRef
5.
6.
Nowak B, Stellbrink C, Schaefer WM, et al. Comparison of regional myocardial blood flow and perfusion in dilated cardiomyopathy and left bundle branch block: Role of wall thickening. J Nucl Med 2004;45:414-8.PubMed
7.
Metadata
Title
Refining the role of gated SPECT for predicting clinical response to cardiac resynchronization therapy: Are we using the right tool at the wrong time?
Author
Dennis A. Calnon, MD, MASNC
Publication date
01-08-2020
Publisher
Springer International Publishing
Published in
Journal of Nuclear Cardiology / Issue 4/2020
Print ISSN: 1071-3581
Electronic ISSN: 1532-6551
DOI
https://doi.org/10.1007/s12350-019-01767-z

Other articles of this Issue 4/2020

Journal of Nuclear Cardiology 4/2020 Go to the issue

ASNC President’s Message

The new normal

REVIEW ARTICLE

A quick glance at selected topics in this issue

EDITORIAL

Approaching perioperative cardiac risk: Forging new strategies against an old enemy

Editorial

PET-derived bone information from 18F-sodium fluoride: A perfect match for whole-body PET/MR attenuation correction?

LETTER TO THE EDITOR

Duration of proton pump inhibitor abstinence before MPI

News

CME INSTRUCTIONS: Nuclear cardiology in the context of multimodality imaging to detect cardiac toxicity from cancer therapeutics: Established and emerging methods

ACC 2024 Congress Coverage

Year in Review: Heart failure and cardiomyopathies

Heart Failure Video

Watch this official video from ACC.24. Dr. Biykem Bozkurt discusses last year's major advances in heart failure and cardiomyopathies.

Watch now

Semaglutide benefits people with type 2 diabetes and obesity-related heart failure

16-04-2024 Type 2 Diabetes News

Incentivised to exercise

11-04-2024 Lifestyle Modifications News

New intervention for STEMI-related cardiogenic shock

10-04-2024 Myocardial Infarction News

» View more highlights on the ACC 2024 congress hub page

Image Credits