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Advances in Therapy
Published in: Advances in Therapy 4/2016

Open Access 01-04-2016 | Review

Cervical Lymph Node Metastasis in Adenoid Cystic Carcinoma of the Larynx: A Collective International Review

Authors: Andrés Coca-Pelaz, Leon Barnes, Alessandra Rinaldo, Antonio Cardesa, Jatin P. Shah, Juan P. Rodrigo, Carlos Suárez, Jean Anderson Eloy, Justin A. Bishop, Kenneth O. Devaney, Lester D. R. Thompson, Bruce M. Wenig, Primož Strojan, Marc Hamoir, Patrick J. Bradley, Douglas R. Gnepp, Carl E. Silver, Pieter J. Slootweg, Asterios Triantafyllou, Vincent Vander Poorten, Michelle D. Williams, Alena Skálová, Henrik Hellquist, Afshin Teymoortash, Jesus E. Medina, K. Thomas Robbins, Karen T. Pitman, Luiz P. Kowalski, Remco de Bree, William M. Mendenhall, Robert P. Takes, Alfio Ferlito

Published in: Advances in Therapy | Issue 4/2016

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Abstract

Adenoid cystic carcinoma (AdCC) of the head and neck is a well-recognized pathologic entity that rarely occurs in the larynx. Although the 5-year locoregional control rates are high, distant metastasis has a tendency to appear more than 5 years post treatment. Because AdCC of the larynx is uncommon, it is difficult to standardize a treatment protocol. One of the controversial points is the decision whether or not to perform an elective neck dissection on these patients. Because there is contradictory information about this issue, we have critically reviewed the literature from 1912 to 2015 on all reported cases of AdCC of the larynx in order to clarify this issue. During the most recent period of our review (1991–2015) with a more exact diagnosis of the tumor histology, 142 cases were observed of AdCC of the larynx, of which 91 patients had data pertaining to lymph node status. Eleven of the 91 patients (12.1%) had nodal metastasis and, based on this low proportion of patients, routine elective neck dissection is therefore not recommended.
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Metadata
Title
Cervical Lymph Node Metastasis in Adenoid Cystic Carcinoma of the Larynx: A Collective International Review
Authors
Andrés Coca-Pelaz
Leon Barnes
Alessandra Rinaldo
Antonio Cardesa
Jatin P. Shah
Juan P. Rodrigo
Carlos Suárez
Jean Anderson Eloy
Justin A. Bishop
Kenneth O. Devaney
Lester D. R. Thompson
Bruce M. Wenig
Primož Strojan
Marc Hamoir
Patrick J. Bradley
Douglas R. Gnepp
Carl E. Silver
Pieter J. Slootweg
Asterios Triantafyllou
Vincent Vander Poorten
Michelle D. Williams
Alena Skálová
Henrik Hellquist
Afshin Teymoortash
Jesus E. Medina
K. Thomas Robbins
Karen T. Pitman
Luiz P. Kowalski
Remco de Bree
William M. Mendenhall
Robert P. Takes
Alfio Ferlito
Publication date
01-04-2016
Publisher
Springer Healthcare
Published in
Advances in Therapy / Issue 4/2016
Print ISSN: 0741-238X
Electronic ISSN: 1865-8652
DOI
https://doi.org/10.1007/s12325-016-0311-z

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WHO estimates that half of all patients worldwide are non-adherent to their prescribed medication. The consequences of poor adherence can be catastrophic, on both the individual and population level.

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New intervention for STEMI-related cardiogenic shock

10-04-2024 Myocardial Infarction News

» View more highlights on the ACC 2024 congress hub page

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