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Indian Journal of Otolaryngology and Head & Neck Surgery

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13-02-2023 | Neck Dissection | Original Article

Incidence of Post Total Laryngectomy Hypothyroidism: Effects of Thyroid Gland Surgery and Post-Operative Radiotherapy

Authors: Ahmed Amin Nassar, Abdelrahman Ahmed Shoaib, Hazem Mohammed Dewidar, Khaled Omar Azooz

Published in: Indian Journal of Otolaryngology and Head & Neck Surgery | Issue 3/2023

Abstract

To record the incidence of hypothyroidism in patients after total laryngectomy, whether with or without postoperative radiation therapy and to analyze the effect of hemithyroidectomy for the development of hypothyroidism. A retrospective study included patients who underwent total laryngectomy (with or without hemithyroidectomy) between 2018 and 2021 for laryngeal carcinoma and/or received postoperative radiotherapy. Thirty-six (45%) of the 80 enrolled patients developed hypothyroidism after a median follow-up of 16 months. In this study, adjuvant radiation and central neck dissection were found to be significantly linked with developing post-operative hypothyroidism (p values: 0.001, 0.007, respectively). The incidence of hypothyroidism in patients treated for laryngeal carcinoma is high, especially after combination treatment of surgery and radiotherapy.

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Title: Incidence of Post Total Laryngectomy Hypothyroidism: Effects of Thyroid Gland Surgery and Post-Operative Radiotherapy
Authors: Ahmed Amin Nassar
Abdelrahman Ahmed Shoaib
Hazem Mohammed Dewidar
Khaled Omar Azooz
Publication date: 13-02-2023
Publisher: Springer India
Keywords: Neck Dissection
Laryngectomy
Radiotherapy
Hemithyroidectomy
Laryngeal Cancer
Thyroidectomy
Hemithyroidectomy
Thyroidectomy
Laryngeal Cancer
Hypothyroidism
Published in: Indian Journal of Otolaryngology and Head & Neck Surgery / Issue 3/2023
Print ISSN: 2231-3796
Electronic ISSN: 0973-7707
DOI: https://doi.org/10.1007/s12070-023-03562-2

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Incidence of Post Total Laryngectomy Hypothyroidism: Effects of Thyroid Gland Surgery and Post-Operative Radiotherapy

Abstract

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

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