Skip to main content
Key Specialties
Cardiology Diabetology Endocrinology Gastroenterology Geriatrics and Gerontology Gynecology and Obstetrics Hematology Infectious Disease Internal Medicine Nephrology Neurology Oncology Pediatrics Respiratory Medicine Rheumatology Surgery
Congress Coverage
2024 ACC Congress 2023 ESMO Congress 2023 EASD Congress 2023 ERS Congress 2023 ESC Congress
Clinical Collections
Advances in Alzheimer’s

Keynote webinar | Spotlight on medication adherence

LIVE: Thursday 27th June 2024, 18:00-19:30 (CEST)
Join our expert panel to discover why you need to understand the drivers of non-adherence in your patients, and how you can optimize medication adherence in your clinics to drastically improve patient outcomes.
ADVANCED SEARCH
Log in
Top
Medical Oncology
Published in: Medical Oncology 1/2011

01-12-2011 | Original Paper

Central nervous system involvement in Hodgkin’s lymphoma

Authors: L. Galán, A. C. Sánchez, B. Cantos, M. Provencio

Published in: Medical Oncology | Special Issue 1/2011

Login to get access

Abstract

Central nervous system involvement in Hodgkin´s lymphoma is extremely rare. We report three cases who had a relapse from the disease involving CNS. The most frequent causes are skull contiguity, meningeal invasion and via the hematogenous route. It is frequent that the association between Epstein–Barr Virus and Hodgkin´s lymphoma, and a biopsy for confirmation, is always required. Diagnostic imaging tests like CT and MRI are useful. The standard treatment remains holocraneal radiotherapy combined with chemotherapy.
Literature
1.
Carbone PP, Kaplan HS, Musshoff K, et al. Report of the Committee on Hodgkin’s disease staging classification. Cancer Res. 1971;31:1860–1.PubMed
2.
Lister TA, Crowther D, Sutcliffe SB, et al. Report of a committee convened to discuss the evaluation and staging of patients with Hodgkin’s disease: Cotswolds meeting. J Clin Oncol. 1989;7:1630–6.PubMed
3.
De Vita VT, Serpick A. Combination chemotherapy in the treatment of advanced Hodgkin’s disease. Proc Amer Ass Cancer Res. 1967;8:13.
4.
Bonadonna G, Zucali R, Monfardini S, et al. Combination chemotherapy of Hodgkin’s disease with adriamycin, bleomycin, vinblastine, and imidazole carboxamide versus MOPP. Cancer. 1975;36:252–9.PubMedCrossRef
5.
Kaplan HS, Rosenberg SA. Extended field radical radiotherapy in advanced Hodgkin’s disease. Cancer Res. 1966;26:1268–76.PubMed
6.
Aragón de la Cruz G, Cardenes H, Otero J, et al. Individual risk of abdominal disease in patients with stages I and II supradiaphragmatic Hodgkin’s disease a rule index based on 341 laparotomized patients. Cancer. 1989;63:1799–803.PubMedCrossRef
7.
Johnson MD, Kinney MC, Scheithauer BW, Briley RJ, Hamilton K, Mc Person WF, Barton JH Jr. Primary intracerebral Hodgkin’s disease mimicking meningioma: Case report. Neurosurgery. 2000;47(2):454–6.PubMedCrossRef
8.
Cuttner J, Meyer R, Huang YP. Intracerebral involvement in Hodgkin’s disease: A report of 6 cases and review of the literature. Cancer. 1979;43(4):1497–506.PubMedCrossRef
9.
Biagi J, MacKenzie R, Lim MS, Sapp M, Berinstein N. Primary Hodgkin’s disease of the CNS in an immunocompetent patient: A case study review of the literature. Neuro-Oncology. 2000;2(4):239–43.PubMed
10.
Hirmiz K, Foyle A, Wilke D, Burrell S, Brownstone R, Ago C, et al. Intracranial presentation of systemic Hodgkin’s disease. Leukemia, Lymphoma. 2004;45(8):1667–71.CrossRef
11.
Sapozink MD, Kaplan HS. Intracraneal Hodgkin’s disease: A report of 12 cases and review of the literature. Cancer. 1983;52:1301–7.PubMedCrossRef
12.
Alvarez F, Road JM, Ancines B, Alvarez MP. Intracranial Hodgkin disease. J Neurosurg Sci. 1985;29:273–7.PubMed
13.
Ogata H, Karikomi M, Araki T, Uchiyama GA. Case of intracranial involvement of Hodgkin disease. Radiat Med. 1993;11:210–3.PubMed
14.
Klein R, Mullges W, Bendszus M, et al. Primary intracerebral Hodgkin’s disease: Report of a case with Epstein-Barr virus association and review of the literature. Am J Surg Pathol. 1999;23:477–81.PubMedCrossRef
15.
Apollonsky N, Edelman M, Johnson A, et al. Intracerebral presentation of Hodgkin disease mimicking meningioma in a young woman. J Pediatr Hematol Oncol. 2008;30:369–72.PubMedCrossRef
16.
Pansegrau, et al. Hodgkin’s Lymphoma involving the CNS. J Clin Oncol. 2007;25(11):1437–8.CrossRef
17.
Guermazi A, Brice P, Kerviler E, et al. Extranodal Hodgkin disease: Spectrum of disease. RadioGraphics. 2001;21:161–79.PubMed
18.
19.
Marshall G, Roessmann V, van den Noort S. Invasive Hodgkin’s disease of the brain. Report of 2 new cases and review of the American and European literature with clinical-pathological correlation. Cancer. 1968;2:621–30.CrossRef
20.
21.
Orlowski EP, Hansen RM, Anderson T, Hanson GA, Kun LE, Pisciotta AV. Hodgkin disease with leptomeningeal involvement, report of a case with long survival. Cancer. 1984;53:1833–5.PubMedCrossRef
22.
Chim CS, Shek TW, Ooi GC, Liang R. Unusual features of Hodgkin disease. Case 2: Meningeal relapse in Hodgkin disease. J Clin Oncol. 2000;18:1153–5.PubMed
23.
Vera R, Enriquez R, Papc R. Hodgkin’s disease, intracraneal involvement. Report of a case and review of the literature. Am J Clin Oncol. 1985;8:73–6.PubMedCrossRef
Metadata
Title
Central nervous system involvement in Hodgkin’s lymphoma
Authors
L. Galán
A. C. Sánchez
B. Cantos
M. Provencio
Publication date
01-12-2011
Publisher
Springer US
Published in
Medical Oncology / Issue Special Issue 1/2011
Print ISSN: 1357-0560
Electronic ISSN: 1559-131X
DOI
https://doi.org/10.1007/s12032-010-9692-z

Other articles of this Special Issue 1/2011

Medical Oncology 1/2011 Go to the issue

Original paper

Predictors of mammography use in older women with disability: the patients’ perspectives

Original Paper

Antitumor efficacy of a photodynamic therapy-generated dendritic cell glioma vaccine

Original Paper

The functional polymorphism in monocyte chemoattractant protein-1 gene increases susceptibility to gastric cancer

Orginal Paper

Bilateral papilledema on sunitinib therapy for advanced renal cell carcinoma

Original Paper

Potential role of serum level of soluble CD44 and IFN-γ in B-cell chronic lymphocytic leukemia

OriginalPaper

Sunitinib-induced severe hypothyroidism with cardiac compromise
Live Webinar | 27-06-2024 | 18:00 (CEST)

Keynote webinar | Spotlight on medication adherence

Reserve your place

Live: Thursday 27th June 2024, 18:00-19:30 (CEST)

WHO estimates that half of all patients worldwide are non-adherent to their prescribed medication. The consequences of poor adherence can be catastrophic, on both the individual and population level.

Join our expert panel to discover why you need to understand the drivers of non-adherence in your patients, and how you can optimize medication adherence in your clinics to drastically improve patient outcomes.

Prof. Kevin Dolgin
Prof. Florian Limbourg
Prof. Anoop Chauhan
Developed by: Springer Medicine
Obesity Clinical Trial Summary

At a glance: The STEP trials

Read more

A round-up of the STEP phase 3 clinical trials evaluating semaglutide for weight loss in people with overweight or obesity.

Developed by: Springer Medicine

Highlights from the ACC 2024 Congress

Year in Review: Pediatric cardiology

Pediatric Cardiology Video

Watch Dr. Anne Marie Valente present the last year's highlights in pediatric and congenital heart disease in the official ACC.24 Year in Review session.

Year in Review: Pulmonary vascular disease

Cardiopulmonary Comorbidity Video

The last year's highlights in pulmonary vascular disease are presented by Dr. Jane Leopold in this official video from ACC.24.

Year in Review: Valvular heart disease

Valvular Heart Disease Video

Watch Prof. William Zoghbi present the last year's highlights in valvular heart disease from the official ACC.24 Year in Review session.

Year in Review: Heart failure and cardiomyopathies

Heart Failure Video

Watch this official video from ACC.24. Dr. Biykem Bozkurt discusses last year's major advances in heart failure and cardiomyopathies.

ACC 2024 Congress Coverage

Year in Review: Heart failure and cardiomyopathies

Heart Failure Video

Watch this official video from ACC.24. Dr. Biykem Bozkurt discusses last year's major advances in heart failure and cardiomyopathies.

Watch now

Semaglutide benefits people with type 2 diabetes and obesity-related heart failure

16-04-2024 Type 2 Diabetes News

Incentivised to exercise

11-04-2024 Lifestyle Modifications News

New intervention for STEMI-related cardiogenic shock

10-04-2024 Myocardial Infarction News

» View more highlights on the ACC 2024 congress hub page

Image Credits