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Journal of Clinical Monitoring and Computing

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01-10-2015 | Original Research

Monitoring CO₂ in shock states

Authors: Pierre-Eric Danin, Nils Siegenthaler, Jacques Levraut, Gilles Bernardin, Jean Dellamonica, Karim Bendjelid

Published in: Journal of Clinical Monitoring and Computing | Issue 5/2015

Abstract

The primary end point when treating acute shock is to restore blood circulation, mainly by reaching macrocirculatory parameters. However, even if global haemodynamic goals can be achieved, microcirculatory perfusion may remain impaired, leading to cellular hypoxia and organ damage. Interestingly, few methods are currently available to measure the adequacy of organ blood flow and tissue oxygenation. The rise in tissue partial pressure of carbon dioxide (CO₂) has been observed when tissue perfusion is decreased. In this regard, tissue partial pressure of CO₂ has been proposed as an early and reliable marker of tissue hypoxia even if the mechanisms of tissue partial pressure in CO₂ rise during hypoperfusion remain unclear. Several technologies allow the estimation of CO₂ content from different body sites: vascular, tissular (in hollow organs, mucosal or cutaneous), and airway. These tools remain poorly evaluated, and some are used but are not widely used in clinical practice. The present review clarifies the physiology of increasing tissue CO₂ during hypoperfusion and underlines the specificities of the different technologies that allow bedside estimation of tissue CO₂ content.

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Title: Monitoring CO2 in shock states
Authors: Pierre-Eric Danin
Nils Siegenthaler
Jacques Levraut
Gilles Bernardin
Jean Dellamonica
Karim Bendjelid
Publication date: 01-10-2015
Publisher: Springer Netherlands
Published in: Journal of Clinical Monitoring and Computing / Issue 5/2015
Print ISSN: 1387-1307
Electronic ISSN: 1573-2614
DOI: https://doi.org/10.1007/s10877-014-9638-7

Keynote webinar | Spotlight on medication adherence

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Monitoring CO₂ in shock states

Abstract

Keynote webinar | Spotlight on medication adherence

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