Published in:
01-09-2020 | Antiarrhythmic Drugs
Bipolar radiofrequency ablation delivered from coronary veins and adjacent endocardium for treatment of refractory left ventricular summit arrhythmias
Published in: Journal of Interventional Cardiac Electrophysiology | Issue 3/2020
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Background
Radiofrequency catheter ablation (RFCA) of premature ventricular complexes (PVC) and ventricular tachycardia (VT) can be an effective method of treatment. However, when arrhythmia originates from the left ventricular summit (LVS), an ablation performed with conventional unipolar energy sources can be challenging and may require alternative approaches. Bipolar RFCA from coronary veins and an adjacent endocardium in cases of refractory PVC/VT has not yet been studied.
Methods
We retrospectively analysed cases of consecutive patients who underwent bipolar ablation in whom conventional unipolar ablation of LVS PVC/VT and antiarrhythmic drugs failed to abolish arrhythmia. Bipolar RFCA was delivered from the earliest PVC/VT activation located in the coronary venous circulation and opposite LV endocardial sites.
Results
A total number of 4 patients (1 female, age 55 ± 10 years) underwent bipolar ablation of LVS from coronary veins and an adjacent endocardium. Bipolar RFCA led to acute elimination of PVC/VT in all patients. A mean bipolar RFCA time was 244 ± 15 s. There were no complications during procedures and all antiarrhythmic drugs were discontinued. A follow-up lasted 15 ± 4 months; there was no VT recurrence and the mean 83 ± 27 % PVC burden reduction (24250 ± 1372 vs. 3000 ± 3600 PVC/d; p = 0.0228) was achieved. All patients remained symptom-free.
Conclusions
Bipolar RFCA from coronary veins and an opposite endocardium can be used for safe and successful treatment of PVC/VT originating from a deep LV summit.