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Published in: Breast Cancer Research and Treatment 3/2010

01-08-2010 | Letter to the Editor

Human papillomavirus is not associated with breast carcinoma

Authors: Dilek Yavuzer, Taflan Salepci, Nimet Karadayi, Huseyin Baloglu, Zafer Kucukodaci

Published in: Breast Cancer Research and Treatment | Issue 3/2010

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Excerpt

Breast cancer is the most common cancer in women, accounting for 23% of all female cancers around the world. Research on its etiology has focused primarily on genetic and environmental factors [1]. Infectious etiology in carcinogenesis has long been suggested by epidemiological and experimental studies. Current estimates suggest that approximately 15–20% of all cancers worldwide appear to be associated with viral infections, and several human DNA viruses are now accepted as causative agent of specific malignancies [2]. Human papillomavirus (HPV) is one of the viruses and is responsible for causing virtually all cases of cervical cancer in women [2]. A number of studies have reported HPV DNA detection in extragenital cancers, although the etiological involvement of HPV in those malignancies is still controversial [3]. The aim of the present study was to investigate a possible presence of HPV DNA in breast cancer tissue in a population of Turkish women and discuss the results in the light of literature. …
Literature
1.
go back to reference Parkin DM, Bray F, Ferlay J, Pisani P (2005) Global cancer statistics, 2002. CA Cancer J Clin 55(2):74–108CrossRefPubMed Parkin DM, Bray F, Ferlay J, Pisani P (2005) Global cancer statistics, 2002. CA Cancer J Clin 55(2):74–108CrossRefPubMed
3.
go back to reference Gillison ML, Shah KV (2003) Role of mucosal human papillomavirus in nongenital cancers. J Natl Cancer Inst Monogr 31:57–65PubMed Gillison ML, Shah KV (2003) Role of mucosal human papillomavirus in nongenital cancers. J Natl Cancer Inst Monogr 31:57–65PubMed
4.
go back to reference Di Lonardo A, Venuti A, Marcante ML (1992) Human papillomavirus in breast cancer. Breast Cancer Res Treat 21(2):95–100CrossRefPubMed Di Lonardo A, Venuti A, Marcante ML (1992) Human papillomavirus in breast cancer. Breast Cancer Res Treat 21(2):95–100CrossRefPubMed
5.
go back to reference Mendizabal-Ruiz AP, Morales JA, Ramirez-Jirano LJ, Padilla-Rosas M, Moran-Moguel MC, Montoya-Fuentes H (2009) Low frequency of human papillomavirus DNA in breast cancer tissue. Breast Cancer Res Treat 114(1):189–194CrossRefPubMed Mendizabal-Ruiz AP, Morales JA, Ramirez-Jirano LJ, Padilla-Rosas M, Moran-Moguel MC, Montoya-Fuentes H (2009) Low frequency of human papillomavirus DNA in breast cancer tissue. Breast Cancer Res Treat 114(1):189–194CrossRefPubMed
6.
go back to reference De Villiers EM, Sandstrom RE, Zur Hausen H, Buck CE (2005) Presence of papillomavirus sequences in condylomatous lesions of the mamillae and invasive carcinoma of the breast. Breast Cancer Res 7(1):R1–R11CrossRefPubMed De Villiers EM, Sandstrom RE, Zur Hausen H, Buck CE (2005) Presence of papillomavirus sequences in condylomatous lesions of the mamillae and invasive carcinoma of the breast. Breast Cancer Res 7(1):R1–R11CrossRefPubMed
7.
go back to reference Khan NA, Castillo A, Koriyama C, Kijima Y, Umetika Y, Ohi Y, Higashi M, Sagara Y, Yoshinaka H, Tsuji T, Natsugoe S, Douchi T, Eizuru Y, Akiba S (2008) Human papillomavirus detected in female breast carcinomas in Japan. Br J Cancer 99(3):408–414CrossRefPubMed Khan NA, Castillo A, Koriyama C, Kijima Y, Umetika Y, Ohi Y, Higashi M, Sagara Y, Yoshinaka H, Tsuji T, Natsugoe S, Douchi T, Eizuru Y, Akiba S (2008) Human papillomavirus detected in female breast carcinomas in Japan. Br J Cancer 99(3):408–414CrossRefPubMed
8.
go back to reference Widschwendter A, Brunhuber T, Wiedemair A, Mueller-Holzner E, Marth C (2004) Detection of human papillomavirus DNA in breast cancer of patients with cervical cancer history. J Clin Virol 31(4):292–297CrossRefPubMed Widschwendter A, Brunhuber T, Wiedemair A, Mueller-Holzner E, Marth C (2004) Detection of human papillomavirus DNA in breast cancer of patients with cervical cancer history. J Clin Virol 31(4):292–297CrossRefPubMed
9.
go back to reference De Cremoux P, Thioux M, Lebigot I, Sigal-Zafrani B, Salmon R, Sastre-Garau X (2008) No evidence of human papillomavirus DNA sequences in invasive breast carcinoma. Breast Cancer Res Treat 109(1):55–58CrossRefPubMed De Cremoux P, Thioux M, Lebigot I, Sigal-Zafrani B, Salmon R, Sastre-Garau X (2008) No evidence of human papillomavirus DNA sequences in invasive breast carcinoma. Breast Cancer Res Treat 109(1):55–58CrossRefPubMed
10.
go back to reference Lindel K, Forster A, Altermatt HJ, Greiner R, Gruber G (2007) Breast cancer and human papillomavirus (HPV) infection: no evidence of a viral etiology in a group of Swiss women. Breast 16(2):172–177CrossRefPubMed Lindel K, Forster A, Altermatt HJ, Greiner R, Gruber G (2007) Breast cancer and human papillomavirus (HPV) infection: no evidence of a viral etiology in a group of Swiss women. Breast 16(2):172–177CrossRefPubMed
11.
go back to reference Milutin Gasperov N, Sabol I, Motavina M, Spaventi S, Grce M (2008) Detection and typing of human papillomaviruses combining different methods: polymerase chain reaction, restriction fragment length polymorphism, line probe assay and sequencing. Pathol Oncol Res 14(4):355–363CrossRefPubMed Milutin Gasperov N, Sabol I, Motavina M, Spaventi S, Grce M (2008) Detection and typing of human papillomaviruses combining different methods: polymerase chain reaction, restriction fragment length polymorphism, line probe assay and sequencing. Pathol Oncol Res 14(4):355–363CrossRefPubMed
12.
go back to reference Inal MM, Kose S, Yildirim Y, Ozdemir Y, Toz E, Ertopçu K, Ozelmas I, Tinar S (2007) The relationship between human papillomavirus infection and cervical intraepithelial neoplasia in Turkish women. Int J Gynecol Cancer 17(6):1266–1270CrossRefPubMed Inal MM, Kose S, Yildirim Y, Ozdemir Y, Toz E, Ertopçu K, Ozelmas I, Tinar S (2007) The relationship between human papillomavirus infection and cervical intraepithelial neoplasia in Turkish women. Int J Gynecol Cancer 17(6):1266–1270CrossRefPubMed
13.
go back to reference De Vuyst H, Clifford G, Li N, Franceschi S (2009) HPV infection in Europe. Eur J Cancer 45(15):2632–2639CrossRefPubMed De Vuyst H, Clifford G, Li N, Franceschi S (2009) HPV infection in Europe. Eur J Cancer 45(15):2632–2639CrossRefPubMed
Metadata
Title
Human papillomavirus is not associated with breast carcinoma
Authors
Dilek Yavuzer
Taflan Salepci
Nimet Karadayi
Huseyin Baloglu
Zafer Kucukodaci
Publication date
01-08-2010
Publisher
Springer US
Published in
Breast Cancer Research and Treatment / Issue 3/2010
Print ISSN: 0167-6806
Electronic ISSN: 1573-7217
DOI
https://doi.org/10.1007/s10549-010-0963-3

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