Published in:
01-08-2010 | Letter to the Editor
Human papillomavirus is not associated with breast carcinoma
Authors:
Dilek Yavuzer, Taflan Salepci, Nimet Karadayi, Huseyin Baloglu, Zafer Kucukodaci
Published in:
Breast Cancer Research and Treatment
|
Issue 3/2010
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Excerpt
Breast cancer is the most common cancer in women, accounting for 23% of all female cancers around the world. Research on its etiology has focused primarily on genetic and environmental factors [
1]. Infectious etiology in carcinogenesis has long been suggested by epidemiological and experimental studies. Current estimates suggest that approximately 15–20% of all cancers worldwide appear to be associated with viral infections, and several human DNA viruses are now accepted as causative agent of specific malignancies [
2]. Human papillomavirus (HPV) is one of the viruses and is responsible for causing virtually all cases of cervical cancer in women [
2]. A number of studies have reported HPV DNA detection in extragenital cancers, although the etiological involvement of HPV in those malignancies is still controversial [
3]. The aim of the present study was to investigate a possible presence of HPV DNA in breast cancer tissue in a population of Turkish women and discuss the results in the light of literature. …