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Keynote webinar | Spotlight on medication adherence

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Join our expert panel to discover why you need to understand the drivers of non-adherence in your patients, and how you can optimize medication adherence in your clinics to drastically improve patient outcomes.
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AIDS and Behavior
Published in: AIDS and Behavior 8/2014

01-08-2014 | Original Paper

Risk and Protective Factors for Retention in HIV Care

Authors: Drenna Waldrop-Valverde, Ying Guo, Raymond L. Ownby, Allan Rodriguez, Deborah L. Jones

Published in: AIDS and Behavior | Issue 8/2014

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Abstract

Retention in care for HIV is essential for effective disease management; however, factors that may confer risk or protection for adherence to regular HIV care are less well understood. This study tested whether HIV-associated cognitive impairment (CI) and low health literacy reduced adherence to routine HIV medical and phlebotomy visits and if social support and patient-provider relationship conferred a protective effect. Participants were 210 HIV-infected patients enrolled in outpatient care and followed for 28-weeks. Results showed that those attending >75 % of phlebotomy visits were more likely to be virally suppressed. Health literacy was unassociated with adherence to medical or phlebotomy visits. CI was not directly related to medical or phlebotomy visit adherence; however those with CI and greater use of social support were less likely to miss medical visits. Utilizing social support may be an effective means of managing visit adherence, especially among patients with CI.
Literature
1.
Marks G, Gardner LI, Craw J, et al. The spectrum of engagement in HIV care: do more than 19 % of HIV-infected persons in the US have undetectable viral load? Clin Infect Dis. 2011;53(11):1168–9 author’s reply 9–70.PubMedCrossRef
2.
Vyavaharkar M, Moneyham L, Corwin S, Saunders R, Annang L, Tavakoli A. Relationships between stigma, social support, and depression in HIV-infected African American women living in the rural Southeastern United States. J Assoc Nurses AIDS Care. 2010;21(2):144–52.PubMedCentralPubMedCrossRef
3.
Mugavero MJ, Lin HY, Allison JJ, et al. Failure to establish HIV care: characterizing the “no show” phenomenon. Clin Infect Dis. 2007;45(1):127–30.PubMedCrossRef
4.
Mugavero MJ, Norton WE, Saag MS. Health care system and policy factors influencing engagement in HIV medical care: piecing together the fragments of a fractured health care delivery system. Clin Infect Dis. 2011;52(Suppl 2):S238–46.PubMedCentralPubMedCrossRef
5.
Ulett KB, Willig JH, Lin HY, et al. The therapeutic implications of timely linkage and early retention in HIV care. AIDS Patient Care STDS. 2009;23(1):41–9.PubMedCentralPubMedCrossRef
6.
Vanable PA, Carey MP, Blair DC, Littlewood RA. Impact of HIV-related stigma on health behaviors and psychological adjustment among HIV-positive men and women. AIDS Behav. 2006;10(5):473–82.PubMedCentralPubMedCrossRef
7.
Mugavero MJ, Lin HY, Allison JJ, et al. Racial disparities in HIV virologic failure: do missed visits matter? J Acquir Immune Defic Syndr. 2009;50(1):100–8.PubMedCentralPubMedCrossRef
8.
Catz SL, McClure JB, Jones GN, Brantley PJ. Predictors of outpatient medical appointment attendance among persons with HIV. AIDS Care. 1999;11(3):361–73.PubMedCrossRef
9.
Israelski D, Gore-Felton C, Power R, Wood MJ, Koopman C. Sociodemographic characteristics associated with medical appointment adherence among HIV-seropositive patients seeking treatment in a county outpatient facility. Prev Med. 2001;33(5):470–5.PubMedCrossRef
10.
Giordano T, Visnegarwala F, White A, et al. Patients Referred to an urban HIV clinic frequently fail to establish care: factors predicting failure. AIDS Care. 2005;17:773–83.PubMedCrossRef
11.
Bodenlos JS, Grothe KB, Whitehead D, Konkle-Parker DJ, Jones GN, Brantley PJ. Attitudes toward health care providers and appointment attendance in HIV/AIDS patients. J Assoc Nurses AIDS Care. 2007;18(3):65–73.PubMedCrossRef
12.
Nutbeam D. Evaluating health promotion—progress, problems and solutions. Health Promot Int. 1998;13:27–44.CrossRef
13.
Berkman ND, Dewalt DA, Pignone MP, et al. Literacy and health outcomes. Rockville, MD: RTI-University of North Carolina Evidence Based Practice Center, 2004 January. Report No: 04-E007-2 Contract No: 290-02-0016.
14.
Baker D, Gazmararian J, Williams M, Scott T, Parker R, Green D. Functional health literacy and the risk of hospital admission among Medicare managed care enrollees. Am J Public Health. 2002;92(8):1278–83.PubMedCentralPubMedCrossRef
15.
Davis TC, Arnold C, Berkel HJ, Nandy I, Jackson RH, Glass J. Knowledge and attitude on screening mammography among low-literate, low-income women. Cancer. 1996;78(9):1912–20.PubMedCrossRef
16.
Lindau ST, Tomori C, Lyons T, Langseth L, Bennett CL, Garcia P. The association of health literacy with cervical cancer prevention knowledge and health behaviors in a multiethnic cohort of women. Am J Obstet Gynecol. 2002;186(5):938–43.PubMedCrossRef
17.
Scott TL, Gazmararian JA, Williams MV, Baker DW. Health literacy and preventive health care use among Medicare enrollees in a managed care organization. Med Care. 2002;40(5):395–404.PubMedCrossRef
18.
Weiss BD, Blanchard JS, McGee DL, et al. Illiteracy among Medicaid recipients and its relationship to health care costs. J Health Care Poor Underserved. 1994;5(2):99–111.PubMedCrossRef
19.
Heaton RK, Clifford DB, Franklin DR Jr, et al. HIV-associated neurocognitive disorders persist in the era of potent antiretroviral therapy: CHARTER Study. Neurology. 2010;75(23):2087–96.PubMedCentralPubMedCrossRef
20.
Heaton RK, Franklin DR, Ellis RJ, et al. HIV-associated neurocognitive disorders before and during the era of combination antiretroviral therapy: differences in rates, nature, and predictors. J Neurovirol. 2011;17(1):3–16.PubMedCentralPubMedCrossRef
21.
Waldrop-Valverde D, Jones DL, Gould F, Kumar M, Ownby RL. Neurocognition, health-related reading literacy, and numeracy in medication management for HIV infection. AIDS Patient Care STDS. 2010;24(8):477–84.PubMedCentralPubMedCrossRef
22.
23.
Lee S-YD, Arozullah AM, Cho YI. Health literacy, social support, and health: a research agenda. Soc Sci Med. 2004;58(7):1309–21.PubMedCrossRef
24.
Kirsch IS. Adult literacy in America: a first look at the results of the National Adult Literacy Survey: ERIC; 1993.
25.
Wolf MS, Davis TC, Osborn CY, Skripkauskas S, Bennett CL, Makoul G. Literacy, self-efficacy, and HIV medication adherence. Patient Educ Couns. 2007;65(2):253–60.PubMedCrossRef
26.
Antonucci TC. Social relations. In: Birren JE, Schaie KW, editors. Handbook of the psychology of aging. San Diego: Academic Press; 2001. pp. 53–77.
27.
Sherman AM. Social relations and depressive symptoms in older adults with knee osteoarthritis. Soc Sci Med. 2003;56(2):247–57.PubMedCrossRef
28.
Cohen CI, Teresi J, Holmes D. Social networks, stress, and physical health: a longitudinal study of an inner-city elderly population. J Gerontol. 1985;40(4):478–86.PubMedCrossRef
29.
Adamis D, Ball C. Physical morbidity in elderly psychiatric inpatients: prevalence and possible relations between the major mental disorders and physical illness. Int J Geriatr Psychiatry. 2000;15(3):248–53.PubMedCrossRef
30.
31.
Agwu AL, Fleishman JA, Korthuis PT, et al. Disparities in antiretroviral treatment: a comparison of behaviorally HIV-infected youth and adults in the HIV research network. J Acquir Immune Defic Syndr. 2011;58(1):100–7.PubMedCentralPubMedCrossRef
32.
Rickwood DJ, Braithwaite VA. Social-psychological factors affecting help-seeking for emotional problems. Soc Sci Med. 1994;39(4):563–72.PubMedCrossRef
33.
Ali NS. Prediction of coronary heart disease preventive behaviors in women: a test of the health belief model. Women Health. 2002;35(1):83–96.PubMedCrossRef
34.
Wenger GC, Tucker I. Using network variation in practice: identification of support network type. Health Soc Care Community. 2002;10(1):28–35.PubMedCrossRef
35.
Levine C, Zuckerman C. The trouble with families: toward an ethic of accommodation. Ann Intern Med. 1999;130(2):148–52.PubMedCrossRef
36.
Holahan CJ, Moos RH, Bonin L. Social support, coping, and psychological adjustment: a resource model. New York: Plenum Press; 1997.
37.
Pearlin LI. Stress and mental health: a conceptual overview. Cambridge: Cambridge University Press; 1999.
38.
Catz SL, Kelly JA, Bogart LM, Benotsch EG, McAuliffe TL. Patterns, correlates, and barriers to medication adherence among persons prescribed new treatments for HIV disease. Health Psychol. 2000;19(2):124–33.PubMedCrossRef
39.
Gonzalez JS, Penedo FJ, Antoni MH, et al. Social support, positive states of mind, and HIV treatment adherence in men and women living with HIV/AIDS. Health Psychol. 2004;23(4):413–8.PubMedCrossRef
40.
Malcolm SE, Ng JJ, Rosen RK, Stone VE. An examination of HIV/AIDS patients who have excellent adherence to HAART. AIDS Care. 2003;15(2):251–61.PubMedCrossRef
41.
Saha S, Arbelaez JJ, Cooper LA. Patient–physician relationships and racial disparities in the quality of health care. Am J Public Health. 2003;93(10):1713–9.PubMedCentralPubMedCrossRef
42.
Whetten K, Leserman J, Whetten R, et al. Exploring lack of trust in care providers and the government as a barrier to health service use. Am J Public Health. 2006;96(4):716–21.PubMedCentralPubMedCrossRef
43.
Mallinson RK, Rajabiun S, Coleman S. The provider role in client engagement in HIV care. AIDS Patient Care STDS. 2007;21(S1):S77–84.
44.
Flickinger TE, Saha S, Moore RD, Beach MC. Higher quality communication and relationships are associated with improved patient engagement in HIV care. J Acquir Immune Defic Syndr. 2013;63(3):362–6.PubMedCentralPubMedCrossRef
45.
46.
Baker DW, Williams MV, Parker RM, Gazmararian JA. Development of a brief test to measure functional health literacy. Patient Educ Couns. 1999;38:33–42.PubMedCrossRef
47.
Bakken S, Holzemer WL, Brown MA, et al. Relationships between perception of engagement with health care provider and demographic characteristics, health status, and adherence to therapeutic regimen in persons with HIV/AIDS. AIDS Patient Care STDS. 2000;14(4):189–97.PubMedCrossRef
48.
Zich J, Temoshok L. Perceptions of social support in men with AIDS and ARC: relationships with distress and hardiness. J Appl Soc Psych. 1987;17(3):193–215.CrossRef
49.
Partington JE, Leitner RG. Partington’s pathway test. Psychol Serv Bull. 1949;1:9–20.
50.
Meyers J, Meyers K. The Meyers scoring system for the Rey Complex figure and the recognition trial: professional manual. Odessa: Psychological Assessment Resources; 1995.
51.
DeFillipis N, McCampbell E. Manual for the booklet category test. Odessa: Psychological Assessment Resources; 1991.
52.
Wechsler D. Wechsler adult intelligence scale (3rd ed) manual. New York: The Psychological Corporation; 1997.
53.
Delis D, Kramer J, Kaplan E, Ober B. California verbal learning test: adult version manual. San Antonio: The Psychological Corporation; 1987.
54.
Smith A. Symbol digit modalities test. Los Angeles: Western Psychological Services; 1991.
55.
Klove H. Clinical neuropsychology. In: Forster FM, editor. The medical clinics of North America. New York: Saunders; 1963.
56.
Miller EN. California computerized assessment package. Los Angeles: Norland Software; 1990.
57.
Andresen EM, Malmgren JA, Carter WB, Patrick DL. Screening for depression in well older adults: evaluation of a short form of the CES-D (Center for Epidemiologic Studies Depression Scale). Am J Prev Med. 1994;10(2):77–84.PubMed
58.
59.
McLellan AT, Kushner H, Metzger D, et al. The fifth edition of the addiction severity index. J Subst Abuse Treat. 1992;9(3):199–213.PubMedCrossRef
60.
Mugavero MJ, Westfall AO, Zinski A, et al. Measuring retention in HIV care: the elusive gold standard. J Acquir Immune Defic Syndr. 2012;61(5):574–80.PubMedCentralPubMedCrossRef
61.
Collett D. Modelling binary data. 2nd ed. London: Chapman and Hall; 2002.
62.
Engels JM, Diehr P. Imputation of missing longitudinal data: a comparison of methods. J Clin Epidemiol. 2003;56(10):968–76.PubMedCrossRef
63.
Waldrop-Valverde D, Jones DL, Weiss S, Kumar M, Metsch L. The effects of low literacy and cognitive impairment on medication adherence in HIV-positive injecting drug users. AIDS Care. 2008;20(10):1202–10.PubMedCrossRef
64.
Waldrop-Valverde D, Ownby RL, Wilkie FL, Mack A, Kumar M, Metsch L. Neurocognitive aspects of medication adherence in HIV-positive injecting drug users. AIDS Behav. 2006;10(3):287–97.PubMedCrossRef
65.
Ettenhofer ML, Foley J, Castellon SA, Hinkin CH. Reciprocal prediction of medication adherence and neurocognition in HIV/AIDS. Neurology. 2010;74(15):1217–22.PubMedCentralPubMedCrossRef
66.
Gorman AA, Foley JM, Ettenhofer ML, Hinkin CH, van Gorp WG. Functional consequences of HIV-associated neuropsychological impairment. Neuropsychol Rev. 2009;19(2):186–203.PubMedCentralPubMedCrossRef
67.
68.
Hinkin CH, Castellon SA, Durvasula RS, et al. Medication adherence among HIV + adults: effects of cognitive dysfunction and regimen complexity. Neurology. 2002;59(12):1944–50.PubMedCentralPubMedCrossRef
69.
Hinkin CH, Hardy DJ, Mason KI, et al. Medication adherence in HIV-infected adults: effect of patient age, cognitive status, and substance abuse. AIDS. 2004;18(Suppl 1):S19–25.PubMedCentralPubMedCrossRef
70.
Traeger L, O’Cleirigh C, Skeer M, Mayer K, Safren SA. Risk factors for missed HIV primary care visits among men who have sex with men. J Behav Med. 2011;35(5):548–56.PubMedCentralPubMedCrossRef
Metadata
Title
Risk and Protective Factors for Retention in HIV Care
Authors
Drenna Waldrop-Valverde
Ying Guo
Raymond L. Ownby
Allan Rodriguez
Deborah L. Jones
Publication date
01-08-2014
Publisher
Springer US
Published in
AIDS and Behavior / Issue 8/2014
Print ISSN: 1090-7165
Electronic ISSN: 1573-3254
DOI
https://doi.org/10.1007/s10461-013-0633-7

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