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Keynote webinar | Spotlight on medication adherence

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Join our expert panel to discover why you need to understand the drivers of non-adherence in your patients, and how you can optimize medication adherence in your clinics to drastically improve patient outcomes.
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AIDS and Behavior
Published in: AIDS and Behavior 1/2013

01-01-2013 | Original Paper

Memory-Based Strategies for Antiretroviral Medication Management: An Evaluation of Clinical Predictors, Adherence Behavior Awareness, and Effectiveness

Authors: K. Blackstone, S. P. Woods, E. Weber, I. Grant, D. J. Moore, The HNRP Group

Published in: AIDS and Behavior | Issue 1/2013

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Abstract

“Forgetting” is the most commonly endorsed reason for missing an antiretroviral therapy (ART) dose, yet little is known about the prevalence, predictors, and effectiveness of the mnemonic strategies to support ART adherence. The current study assessed 28 self-reported memory-based medication strategies in 233 HIV-infected individuals with 30-day ART adherence measured via the medication event monitoring system. Participants endorsed using multiple (8.7 ± 5.6) strategies with the most common being internally-driven. More frequent strategy use was uniquely associated with affective distress, dependent daily functioning, higher non-ART pill burden, and poorer ART adherence. Individuals who used strategies frequently, but perceived them as minimally effective, had more affective, physical, and functional distress. More frequent strategy use was associated with worse ART adherence and was unrelated to perceived effectiveness. Primary reliance on internally-based mnemonic strategies may reflect a lack of awareness of adherence behaviors and may be insufficient to support optimal ART adherence in vulnerable populations.
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Metadata
Title
Memory-Based Strategies for Antiretroviral Medication Management: An Evaluation of Clinical Predictors, Adherence Behavior Awareness, and Effectiveness
Authors
K. Blackstone
S. P. Woods
E. Weber
I. Grant
D. J. Moore
The HNRP Group
Publication date
01-01-2013
Publisher
Springer US
Published in
AIDS and Behavior / Issue 1/2013
Print ISSN: 1090-7165
Electronic ISSN: 1573-3254
DOI
https://doi.org/10.1007/s10461-012-0308-9

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WHO estimates that half of all patients worldwide are non-adherent to their prescribed medication. The consequences of poor adherence can be catastrophic, on both the individual and population level.

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