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Archives of Virology
Published in: Archives of Virology 5/2018

01-05-2018 | Brief Report

The identification and characterization of novel rat hepatitis E virus strains in Bali and Sumbawa, Indonesia

Authors: Putu Prathiwi Primadharsini, Mulyanto, I. Dewa Nyoman Wibawa, Joko Anggoro, Tsutomu Nishizawa, Masaharu Takahashi, Suljid Jirintai, Hiroaki Okamoto

Published in: Archives of Virology | Issue 5/2018

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Abstract

All three genetic groups of ratHEV have been found in Indonesia, suggesting the presence of additional variants of ratHEV in unexamined areas of Indonesia. A total of 242 wild rats were captured in Bali and Sumbawa, Indonesia, during 2014-2016. Among them, 4.1% were seropositive for anti-ratHEV IgG and two (0.8%) had detectable ratHEV RNA: ratESUMBAWA-140L and ratEBali2016D-047L, sharing 84.9-85.4% and 86.9-92.1% nucleotide identity with the reported G2 strains, respectively. The provisional criteria supported the notion that the ratEBali2016D-047L and ratESUMBAWA-140L strains were novel G2 variants. These results suggested the spatial distribution of further divergent ratHEV strains in Indonesia.
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Metadata
Title
The identification and characterization of novel rat hepatitis E virus strains in Bali and Sumbawa, Indonesia
Authors
Putu Prathiwi Primadharsini
Mulyanto
I. Dewa Nyoman Wibawa
Joko Anggoro
Tsutomu Nishizawa
Masaharu Takahashi
Suljid Jirintai
Hiroaki Okamoto
Publication date
01-05-2018
Publisher
Springer Vienna
Published in
Archives of Virology / Issue 5/2018
Print ISSN: 0304-8608
Electronic ISSN: 1432-8798
DOI
https://doi.org/10.1007/s00705-018-3736-7

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