Skip to main content
Key Specialties
Cardiology Diabetology Endocrinology Gastroenterology Geriatrics and Gerontology Gynecology and Obstetrics Hematology Infectious Disease Internal Medicine Nephrology Neurology Oncology Pediatrics Respiratory Medicine Rheumatology Surgery
Congress Coverage
2024 ACC Congress 2023 ESMO Congress 2023 EASD Congress 2023 ERS Congress 2023 ESC Congress
Clinical Collections
Advances in Alzheimer’s

Keynote webinar | Spotlight on medication adherence

LIVE: Thursday 27th June 2024, 18:00-19:30 (CEST)
Join our expert panel to discover why you need to understand the drivers of non-adherence in your patients, and how you can optimize medication adherence in your clinics to drastically improve patient outcomes.
ADVANCED SEARCH
Log in
Top
Archives of Virology
Published in: Archives of Virology 1/2011

01-01-2011 | Original Article

Characterization of H9N2 influenza viruses isolated from Dongting Lake wetland in 2007

Authors: Hongbo Zhang, Bing Xu, Quanjiao Chen, Ze Chen

Published in: Archives of Virology | Issue 1/2011

Login to get access

Abstract

In 2007, a total of eight H9N2 influenza viruses were isolated from the water and fowl feces in Dongting Lake wetland, China. The genomes of the eight viruses were sequenced, and all eight gene segments were subjected to phylogenetic analysis. The results showed that all the isolates belonged to the same genotype, in which the HA, NA and NS gene segments were Chicken/Beijing/94-like; the PB2, PB1, PA and NP gene segments were Chicken/Shanghai/F/98-like; and the M gene was Quail/Hong Kong/G1/97-like. Animal experiments showed low pathogenicity of the selected viruses for chickens, although some chickens died after inoculation. The viruses showed no overt clinical signs in mice, but they could replicate in murine lungs prior to adaptation.
Literature
1.
Aamir UB, Wernery U, Ilyushina N, Webster RG (2007) Characterization of avian H9N2 influenza viruses from United Arab Emirates 2000 to 2003. Virology 361:45–55CrossRefPubMed
2.
3.
Cameron KR, Gregory V, Banks J, Brown IH, Alexander DJ et al (2000) H9N2 subtype influenza A viruses in poultry in Pakistan are closely related to the H9N2 viruses responsible for human infection in Hong Kong. Virology 278:36–41CrossRefPubMed
4.
Guan Y, Shortridge KF, Krauss S, Chin PS, Dyrting KC et al (2000) H9N2 influenza viruses possessing H5N1-like internal genomes continue to circulate in poultry in southeastern China. J Virol 74:9372–9380CrossRefPubMed
5.
Homme PJ, Easterday BC (1970) Avian influenza virus infections. I. Characteristics of influenza A-turkey-Wisconsin-1966 virus. Avian Dis 14:66–74CrossRefPubMed
6.
Kim JA, Cho SH, Kim HS, Seo SH (2006) H9N2 influenza viruses isolated from poultry in Korean live bird markets continuously evolve and cause the severe clinical signs in layers. Vet Microbiol 118:169–176CrossRefPubMed
7.
Nili H, Asasi K (2002) Natural cases and an experimental study of H9N2 avian influenza in commercial broiler chickens of Iran. Avian Pathol 31:247–252CrossRefPubMed
8.
Peiris M, Yuen KY, Leung CW, Chan KH, Ip PL et al (1999) Human infection with influenza H9N2. Lancet 354:916–917CrossRefPubMed
9.
Guan Y, Shortridge KF, Krauss S, Webster RG (1999) Molecular characterization of H9N2 influenza viruses: were they the donors of the “internal” genes of H5N1 viruses in Hong Kong? Proc Natl Acad Sci USA 96:9363–9367CrossRefPubMed
10.
Tosh C, Nagarajan S, Behera P, Rajukumar K, Purohit K et al (2008) Genetic analysis of H9N2 avian influenza viruses isolated from India. Arch Virol 153:1433–1439CrossRefPubMed
11.
Xu KM, Smith GJ, Bahl J, Duan L, Tai H et al (2007) The genesis and evolution of H9N2 influenza viruses in poultry from southern China, 2000 to 2005. J Virol 81:10389–10401CrossRefPubMed
12.
Munster VJ, Baas C, Lexmond P, Waldenstrom J, Wallensten A et al (2007) Spatial, temporal, and species variation in prevalence of influenza A viruses in wild migratory birds. PLoS Pathog 3:e61CrossRefPubMed
13.
Webster RG, Bean WJ, Gorman OT, Chambers TM, Kawaoka Y (1992) Evolution and ecology of influenza A viruses. Microbiol Rev 56:152–179PubMed
14.
Brown JD, Goekjian G, Poulson R, Valeika S, Stallknecht DE (2009) Avian influenza virus in water: infectivity is dependent on pH, salinity and temperature. Vet Microbiol 136:20–26CrossRefPubMed
15.
Brown JD, Swayne DE, Cooper RJ, Burns RE, Stallknecht DE (2007) Persistence of H5 and H7 avian influenza viruses in water. Avian Dis 51:285–289CrossRefPubMed
16.
Stallknecht DE, Shane SM, Kearney MT, Zwank PJ (1990) Persistence of avian influenza viruses in water. Avian Dis 34:406–411CrossRefPubMed
17.
Ito T, Okazaki K, Kawaoka Y, Takada A, Webster RG et al (1995) Perpetuation of influenza A viruses in Alaskan waterfowl reservoirs. Arch Virol 140:1163–1172CrossRefPubMed
18.
Khalenkov A, Laver WG, Webster RG (2008) Detection and isolation of H5N1 influenza virus from large volumes of natural water. J Virol Methods 149:180–183CrossRefPubMed
19.
Hoffmann E, Stech J, Guan Y, Webster RG, Perez DR (2001) Universal primer set for the full-length amplification of all influenza A viruses. Arch Virol 146:2275–2289CrossRefPubMed
20.
Li OT, Barr I, Leung CY, Chen H, Guan Y et al (2007) Reliable universal RT-PCR assays for studying influenza polymerase subunit gene sequences from all 16 haemagglutinin subtypes. J Virol Methods 142:218–222CrossRefPubMed
21.
Kumar S, Tamura K, Nei M (2004) MEGA3: integrated software for molecular evolutionary genetics analysis and sequence alignment. Brief Bioinform 5:150–163CrossRefPubMed
22.
Reed L, Muench H (1938) A simple method of estimating fifty percent endpoints. Am J Hyg 27:493–497
23.
Callan RJ, Hartmann FA, West SE, Hinshaw VS (1997) Cleavage of influenza A virus H1 hemagglutinin by swine respiratory bacterial proteases. J Virol 71:7579–7585PubMed
24.
Guo YJ, Krauss S, Senne DA, Mo IP, Lo KS et al (2000) Characterization of the pathogenicity of members of the newly established H9N2 influenza virus lineages in Asia. Virology 267:279–288CrossRefPubMed
25.
Lin YP, Shaw M, Gregory V, Cameron K, Lim W et al (2000) Avian-to-human transmission of H9N2 subtype influenza A viruses: relationship between H9N2 and H5N1 human isolates. Proc Natl Acad Sci USA 97:9654–9658CrossRefPubMed
26.
Suzuki H, Saito R, Masuda H, Oshitani H, Sato M et al (2003) Emergence of amantadine-resistant influenza A viruses: epidemiological study. J Infect Chemother 9:195–200CrossRefPubMed
27.
Chen H, Deng G, Li Z, Tian G, Li Y et al (2004) The evolution of H5N1 influenza viruses in ducks in southern China. Proc Natl Acad Sci USA 101:10452–10457CrossRefPubMed
28.
Lu JH, Liu XF, Shao WX, Liu YL, Wei DP et al (2005) Phylogenetic analysis of eight genes of H9N2 subtype influenza virus: a mainland China strain possessing early isolates’ genes that have been circulating. Virus Genes 31:163–169CrossRefPubMed
29.
Lang AS, Kelly A, Runstadler JA (2008) Prevalence and diversity of avian influenza viruses in environmental reservoirs. J Gen Virol 89:509–519CrossRefPubMed
30.
Vong S, Ly S, Mardy S, Holl D, Buchy P (2008) Environmental contamination during influenza A virus (H5N1) outbreaks, Cambodia, 2006. Emerg Infect Dis 14:1303–1305CrossRefPubMed
31.
Li KS, Xu KM, Peiris JS, Poon LL, Yu KZ et al (2003) Characterization of H9 subtype influenza viruses from the ducks of southern China: a candidate for the next influenza pandemic in humans? J Virol 77:6988–6994CrossRefPubMed
32.
Xu XJ, Xu GY, Zhou HB, Yu ZJ, Zhang AD et al (2008) Evolutionary characterization of influenza virus A/duck/Hubei/W1/2004 (H9N2) isolated from central China. Virus Genes 36:79–83CrossRefPubMed
33.
Buckler-White AJ, Naeve CW, Murphy BR (1986) Characterization of a gene coding for M proteins which is involved in host range restriction of an avian influenza A virus in monkeys. J Virol 57:697–700PubMed
34.
Ward AC (1995) Specific changes in the M1 protein during adaptation of influenza virus to mouse. Arch Virol 140:383–389CrossRefPubMed
35.
Choi YK, Ozaki H, Webby RJ, Webster RG, Peiris JS et al (2004) Continuing evolution of H9N2 influenza viruses in Southeastern China. J Virol 78:8609–8614CrossRefPubMed
36.
Wu R, Sui ZW, Zhang HB, Chen QJ, Liang WW et al (2008) Characterization of a pathogenic H9N2 influenza A virus isolated from central China in 2007. Arch Virol 153:1549–1555CrossRefPubMed
Metadata
Title
Characterization of H9N2 influenza viruses isolated from Dongting Lake wetland in 2007
Authors
Hongbo Zhang
Bing Xu
Quanjiao Chen
Ze Chen
Publication date
01-01-2011
Publisher
Springer Vienna
Published in
Archives of Virology / Issue 1/2011
Print ISSN: 0304-8608
Electronic ISSN: 1432-8798
DOI
https://doi.org/10.1007/s00705-010-0836-4

Other articles of this Issue 1/2011

Archives of Virology 1/2011 Go to the issue

Rapid Communication

Analysis of codon usage in bovine viral diarrhea virus

Annotated Sequence Record

Determination of the complete nucleotide sequence of a lupine potyvirus isolate from the Czech Republic reveals that it belongs to a new member of the genus Potyvirus

Virology Division News

Trichomonasvirus: a new genus of protozoan viruses in the family Totiviridae

Original Article

Pathogenicity of two Egyptian H5N1 highly pathogenic avian influenza viruses in domestic ducks

Original Article

Restoration of replication-defective dengue type 1 virus bearing mutations in the N-terminal cytoplasmic portion of NS4A by additional mutations in NS4B

Original Article

Analysis of human cytomegalovirus glycoprotein N genotypes in Chinese hematopoietic stem cell transplant recipients
Live Webinar | 27-06-2024 | 18:00 (CEST)

Keynote webinar | Spotlight on medication adherence

Reserve your place

Live: Thursday 27th June 2024, 18:00-19:30 (CEST)

WHO estimates that half of all patients worldwide are non-adherent to their prescribed medication. The consequences of poor adherence can be catastrophic, on both the individual and population level.

Join our expert panel to discover why you need to understand the drivers of non-adherence in your patients, and how you can optimize medication adherence in your clinics to drastically improve patient outcomes.

Prof. Kevin Dolgin
Prof. Florian Limbourg
Prof. Anoop Chauhan
Developed by: Springer Medicine
Obesity Clinical Trial Summary

At a glance: The STEP trials

Read more

A round-up of the STEP phase 3 clinical trials evaluating semaglutide for weight loss in people with overweight or obesity.

Developed by: Springer Medicine

Highlights from the ACC 2024 Congress

Year in Review: Pediatric cardiology

Pediatric Cardiology Video

Watch Dr. Anne Marie Valente present the last year's highlights in pediatric and congenital heart disease in the official ACC.24 Year in Review session.

Year in Review: Pulmonary vascular disease

Cardiopulmonary Comorbidity Video

The last year's highlights in pulmonary vascular disease are presented by Dr. Jane Leopold in this official video from ACC.24.

Year in Review: Valvular heart disease

Valvular Heart Disease Video

Watch Prof. William Zoghbi present the last year's highlights in valvular heart disease from the official ACC.24 Year in Review session.

Year in Review: Heart failure and cardiomyopathies

Heart Failure Video

Watch this official video from ACC.24. Dr. Biykem Bozkurt discusses last year's major advances in heart failure and cardiomyopathies.

ACC 2024 Congress Coverage

Year in Review: Heart failure and cardiomyopathies

Heart Failure Video

Watch this official video from ACC.24. Dr. Biykem Bozkurt discusses last year's major advances in heart failure and cardiomyopathies.

Watch now

Semaglutide benefits people with type 2 diabetes and obesity-related heart failure

16-04-2024 Type 2 Diabetes News

Incentivised to exercise

11-04-2024 Lifestyle Modifications News

New intervention for STEMI-related cardiogenic shock

10-04-2024 Myocardial Infarction News

» View more highlights on the ACC 2024 congress hub page

Image Credits