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01-02-2015 | Original Article

Clinical features and risk factors for development of Bacillus bacteremia among adult patients with cancer: a case-control study

Authors: Jae-Hoon Ko, Cheol-In Kang, Woo Joo Lee, Kyungmin Huh, Jeong Rae Yoo, Kwangmin Kim, Sun Young Cho, Young Eun Ha, Doo Ryeon Chung, Nam Yong Lee, Kyong Ran Peck, Jae-Hoon Song

Published in: Supportive Care in Cancer | Issue 2/2015

Abstract

Purpose

Bacillus species have been frequently reported in recent decades as true pathogens among cancer patients. The purpose of this study was to evaluate the clinical features and risk factors of Bacillus bacteremia among adult patients with cancer.

Methods

A case-control study was performed to identify the risk factors of Bacillus bacteremia among adult patients with cancer at a 1,950-bed tertiary care university hospital. Electronic medical records were reviewed for individuals who were diagnosed with Bacillus bacteremia during the period of January 1995 through December 2012. Each case was matched to two controls with cancer and non-Bacillus bacteremia. Logistic regression model was used to identify independent risk factors for Bacillus bacteremia development.

Results

A total of 86 patients with Bacillus bacteremia were included and compared with 172 control patients. The presence of a central venous catheter and use of extended-spectrum cephalosporin within 1 month were identified to be independent risk factors for the development of Bacillus bacteremia. Hospital stays longer than 14 days, a history of hematopoietic stem cell transplantation, and prior use of glycopeptides had a negative association.

Conclusions

The presence of a central venous catheter and prior use of extended-spectrum cephalosporin within 1 month were independent risk factors for the development of Bacillus bacteremia in adult cancer patients.

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Title: Clinical features and risk factors for development of Bacillus bacteremia among adult patients with cancer: a case-control study
Authors: Jae-Hoon Ko
Cheol-In Kang
Woo Joo Lee
Kyungmin Huh
Jeong Rae Yoo
Kwangmin Kim
Sun Young Cho
Young Eun Ha
Doo Ryeon Chung
Nam Yong Lee
Kyong Ran Peck
Jae-Hoon Song
Publication date: 01-02-2015
Publisher: Springer Berlin Heidelberg
Published in: Supportive Care in Cancer / Issue 2/2015
Print ISSN: 0941-4355
Electronic ISSN: 1433-7339
DOI: https://doi.org/10.1007/s00520-014-2382-1

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Abstract

Purpose

Methods

Results

Conclusions

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