Skip to main content
Top
Published in: Surgical Endoscopy 1/2013

01-01-2013

Gastric leaks after sleeve gastrectomy: a multicenter experience with 2,834 patients

Authors: Nasser Sakran, David Goitein, Asnat Raziel, Andrei Keidar, Nahum Beglaibter, Ronit Grinbaum, Ibrahim Matter, Ricardo Alfici, Ahmad Mahajna, Igor Waksman, Mordechai Shimonov, Ahmad Assalia

Published in: Surgical Endoscopy | Issue 1/2013

Login to get access

Abstract

Background

Laparoscopic sleeve gastrectomy (LSG) remains under scrutiny as a stand-alone bariatric procedure. The most feared complication after LSG is staple line leak.

Methods

Eight bariatric centers in Israel participated in this study. A retrospective analysis was performed by querying all the LSG cases performed between June 2006 and June 2010. The data collected included patient demographics, anthropometrics, and operative and perioperative parameters.

Results

Among the 2,834 patients who underwent LSG, 44 (1.5 %) with gastric leaks were identified. Of these 44 patients, 30 (68 %) were women. The patients had a mean age of 41.5 years and a body mass index (BMI) of 45.4 kg/m2. Intraoperative leak tests and routine postoperative swallow studies were performed with 33 patients, and all but one patient (3 %) failed to detect the leaks. Leaks were diagnosed at a median of 7 days postoperatively: early (0–2 days) in nine cases (20 %), intermediately (3–14 days) in 32 cases (73 %), and late (>14 days) in three cases (7 %). For 38 patients (86 %), there was clinical suspicion, later confirmed by imaging or operative findings. Computed tomography, swallow studies, and methylene blue tests were performed for 37, 21, and 15 patients, respectively, and the results were positive, respectively, for 31 (84 %), 11 (50 %), and 9 (60 %) of these patients. Reoperation was performed for 27 of the patients (61 %). Other treatment methods included percutaneous drainage (n = 28, 63.6 %), endoscopic placement of stents (n = 11, 25 %), clips (n = 1, 2.3 %), and fibrin glue (n = 1, 2.3 %). In 33 of the patients (75 %), the leak site was found in the upper sleeve near the gastroesophageal junction. The median time to leak closure was 40 days (range, 2–270 days), and the overall leak-related mortality rate was 0.14 % (4/2,834).

Conclusion

Gastric leak is the most common cause of major morbidity and mortality after LSG. Routine tests to rule out leaks seem to be superfluous. Rather, selective utilization is recommended. Management options vary, depending mainly on patient disposition. An accepted algorithm for the diagnosis and treatment of gastric leak has yet to be proposed.
Literature
1.
go back to reference Arias E, Martinez PR, Ka Ming Li V et al (2009) Midterm follow-up after sleeve gastrectomy as a final approach for morbid obesity. Obes Surg 19:544–548CrossRefPubMed Arias E, Martinez PR, Ka Ming Li V et al (2009) Midterm follow-up after sleeve gastrectomy as a final approach for morbid obesity. Obes Surg 19:544–548CrossRefPubMed
2.
go back to reference Atkins ER, Preen DB, Jarman C et al (2012) Improved obesity reduction and comorbidity resolution in patients treated with 40-French bougie versus 50-French bougie four years after laparoscopic sleeve gastrectomy: analysis of 294 patients. Obes Surg 22:97–104CrossRefPubMed Atkins ER, Preen DB, Jarman C et al (2012) Improved obesity reduction and comorbidity resolution in patients treated with 40-French bougie versus 50-French bougie four years after laparoscopic sleeve gastrectomy: analysis of 294 patients. Obes Surg 22:97–104CrossRefPubMed
3.
go back to reference Aurora AR, Khaitan L, Saber AA (2011) Sleeve gastrectomy and the risk of leak: a systematic analysis of 4,888 patients. Surg Endosc 26(6):1509–1515CrossRefPubMed Aurora AR, Khaitan L, Saber AA (2011) Sleeve gastrectomy and the risk of leak: a systematic analysis of 4,888 patients. Surg Endosc 26(6):1509–1515CrossRefPubMed
4.
go back to reference Baltasar A, Serra C, Perez N et al (2005) Laparoscopic sleeve gastrectomy: a multipurpose bariatric operation. Obes Surg 15:1124–1128CrossRefPubMed Baltasar A, Serra C, Perez N et al (2005) Laparoscopic sleeve gastrectomy: a multipurpose bariatric operation. Obes Surg 15:1124–1128CrossRefPubMed
6.
go back to reference Baltasar A, Bou R, Bengochea M et al (2007) Use of a Roux limb to correct esophagogastric junction fistulas after sleeve gastrectomy. Obes Surg 17:1408–1410CrossRefPubMed Baltasar A, Bou R, Bengochea M et al (2007) Use of a Roux limb to correct esophagogastric junction fistulas after sleeve gastrectomy. Obes Surg 17:1408–1410CrossRefPubMed
7.
go back to reference Bellanger DE, Greenway FL (2011) Laparoscopic sleeve gastrectomy, 529 cases without a leak: short-term results and technical considerations. Obes Surg 21:146–150CrossRefPubMed Bellanger DE, Greenway FL (2011) Laparoscopic sleeve gastrectomy, 529 cases without a leak: short-term results and technical considerations. Obes Surg 21:146–150CrossRefPubMed
8.
go back to reference Bertucci W, White S, Yadegar J et al (2006) Routine postoperative upper gastroesophageal imaging is unnecessary after laparoscopic Roux-en-Y gastric bypass. Am Surg 72:862–864PubMed Bertucci W, White S, Yadegar J et al (2006) Routine postoperative upper gastroesophageal imaging is unnecessary after laparoscopic Roux-en-Y gastric bypass. Am Surg 72:862–864PubMed
9.
go back to reference Burgos AM, Braghetto I, Csendes A et al (2009) Gastric leak after laparoscopic-sleeve gastrectomy for obesity. Obes Surg 19:1672–1677CrossRefPubMed Burgos AM, Braghetto I, Csendes A et al (2009) Gastric leak after laparoscopic-sleeve gastrectomy for obesity. Obes Surg 19:1672–1677CrossRefPubMed
10.
go back to reference Casella G, Soricelli E, Rizzello M et al (2009) Nonsurgical treatment of staple line leaks after laparoscopic sleeve gastrectomy. Obes Surg 19:821–826CrossRefPubMed Casella G, Soricelli E, Rizzello M et al (2009) Nonsurgical treatment of staple line leaks after laparoscopic sleeve gastrectomy. Obes Surg 19:821–826CrossRefPubMed
11.
go back to reference Clinical Issues Committee of American Society for Metabolic and Bariatric Surgery (2007) Sleeve gastrectomy as a bariatric procedure. Surg Obes Relat Dis 3:573–576CrossRef Clinical Issues Committee of American Society for Metabolic and Bariatric Surgery (2007) Sleeve gastrectomy as a bariatric procedure. Surg Obes Relat Dis 3:573–576CrossRef
12.
go back to reference Conio M, Blanchi S, Repici A et al (2010) Use of an over-the-scope clip for endoscopic sealing of a gastric fistula after sleeve gastrectomy. Endoscopy 42(Suppl 2):E71–E72CrossRefPubMed Conio M, Blanchi S, Repici A et al (2010) Use of an over-the-scope clip for endoscopic sealing of a gastric fistula after sleeve gastrectomy. Endoscopy 42(Suppl 2):E71–E72CrossRefPubMed
13.
go back to reference Cottam D, Qureshi FG, Mattar SG et al (2006) Laparoscopic sleeve gastrectomy as an initial weight loss procedure for high-risk patients with morbid obesity. Surg Endosc 20:859–863CrossRefPubMed Cottam D, Qureshi FG, Mattar SG et al (2006) Laparoscopic sleeve gastrectomy as an initial weight loss procedure for high-risk patients with morbid obesity. Surg Endosc 20:859–863CrossRefPubMed
14.
go back to reference Court I, Wilson A, Benotti P et al (2010) T-tube gastrostomy as a novel approach for distal staple line disruption after sleeve gastrectomy for morbid obesity: case report and review of the literature. Obes Surg 20:519–522CrossRefPubMed Court I, Wilson A, Benotti P et al (2010) T-tube gastrostomy as a novel approach for distal staple line disruption after sleeve gastrectomy for morbid obesity: case report and review of the literature. Obes Surg 20:519–522CrossRefPubMed
15.
go back to reference Csendes A, Braghetto I, Leon P et al (2010) Management of leaks after laparoscopic sleeve gastrectomy in patients with obesity. J Gastrointest Surg 14(9):1343–1348CrossRefPubMed Csendes A, Braghetto I, Leon P et al (2010) Management of leaks after laparoscopic sleeve gastrectomy in patients with obesity. J Gastrointest Surg 14(9):1343–1348CrossRefPubMed
16.
go back to reference Dallal RM, Bailey L, Nahmias N (2007) Back to basics—clinical diagnosis in bariatric surgery: routine drains and upper GI series are unnecessary. Surg Endosc 21:2268–2271CrossRefPubMed Dallal RM, Bailey L, Nahmias N (2007) Back to basics—clinical diagnosis in bariatric surgery: routine drains and upper GI series are unnecessary. Surg Endosc 21:2268–2271CrossRefPubMed
17.
go back to reference Dapri G, Cadiere GB, Himpens J (2009) Feasibility and technique of laparoscopic conversion of adjustable gastric banding to sleeve gastrectomy. Surg Obes Relat Dis 5:72–76CrossRefPubMed Dapri G, Cadiere GB, Himpens J (2009) Feasibility and technique of laparoscopic conversion of adjustable gastric banding to sleeve gastrectomy. Surg Obes Relat Dis 5:72–76CrossRefPubMed
18.
go back to reference Dapri G, Cadiere GB, Himpens J (2009) Reinforcing the staple line during laparoscopic sleeve gastrectomy: prospective randomized clinical study comparing three different techniques. Obes Surg 20:462–467CrossRefPubMed Dapri G, Cadiere GB, Himpens J (2009) Reinforcing the staple line during laparoscopic sleeve gastrectomy: prospective randomized clinical study comparing three different techniques. Obes Surg 20:462–467CrossRefPubMed
19.
go back to reference Daskalakis M, Berdan Y, Theodoridou S et al (2011) Impact of surgeon experience and buttress material on postoperative complications after laparoscopic sleeve gastrectomy. Surg Endosc 25:88–97CrossRefPubMed Daskalakis M, Berdan Y, Theodoridou S et al (2011) Impact of surgeon experience and buttress material on postoperative complications after laparoscopic sleeve gastrectomy. Surg Endosc 25:88–97CrossRefPubMed
20.
go back to reference Deitel M, Crosby RD, Gagner M (2008) The first international consensus summit for sleeve gastrectomy (SG), New York, October 25–27, 2007. Obes Surg 18:487–496CrossRefPubMed Deitel M, Crosby RD, Gagner M (2008) The first international consensus summit for sleeve gastrectomy (SG), New York, October 25–27, 2007. Obes Surg 18:487–496CrossRefPubMed
21.
go back to reference Elazary R, Hazzan D, Appelbaum L et al (2009) Feasibility of sleeve gastrectomy as a revision operation for failed silastic ring vertical gastroplasty. Obes Surg 19:645–649CrossRefPubMed Elazary R, Hazzan D, Appelbaum L et al (2009) Feasibility of sleeve gastrectomy as a revision operation for failed silastic ring vertical gastroplasty. Obes Surg 19:645–649CrossRefPubMed
22.
go back to reference Foletto M, Prevedello L, Bernante P et al (2009) Sleeve gastrectomy as revisional procedure for failed gastric banding or gastroplasty. Surg Obes Relat Dis 6:146–151CrossRefPubMed Foletto M, Prevedello L, Bernante P et al (2009) Sleeve gastrectomy as revisional procedure for failed gastric banding or gastroplasty. Surg Obes Relat Dis 6:146–151CrossRefPubMed
23.
go back to reference Gagner M (2010) Leaks after sleeve gastrectomy are associated with smaller bougies: prevention and treatment strategies. Surg Laparosc Endosc Percutan Tech 20:166–169CrossRefPubMed Gagner M (2010) Leaks after sleeve gastrectomy are associated with smaller bougies: prevention and treatment strategies. Surg Laparosc Endosc Percutan Tech 20:166–169CrossRefPubMed
24.
go back to reference Gagner M, Deitel M, Kalberer TL et al (2009) The Second international consensus summit for sleeve gastrectomy, March 19–21, 2009. Surg Obes Relat Dis 5:476–485CrossRefPubMed Gagner M, Deitel M, Kalberer TL et al (2009) The Second international consensus summit for sleeve gastrectomy, March 19–21, 2009. Surg Obes Relat Dis 5:476–485CrossRefPubMed
25.
go back to reference Goitein D, Goitein O, Feigin A et al (2009) Sleeve gastrectomy: radiologic patterns after surgery. Surg Endosc 23:1559–1563CrossRefPubMed Goitein D, Goitein O, Feigin A et al (2009) Sleeve gastrectomy: radiologic patterns after surgery. Surg Endosc 23:1559–1563CrossRefPubMed
26.
go back to reference Goitein D, Feigin A, Segal-Lieberman G et al (2011) Laparoscopic sleeve gastrectomy as a revisional option after gastric band failure. Surg Endosc 25:2626–2630CrossRefPubMed Goitein D, Feigin A, Segal-Lieberman G et al (2011) Laparoscopic sleeve gastrectomy as a revisional option after gastric band failure. Surg Endosc 25:2626–2630CrossRefPubMed
27.
go back to reference Kehagias I, Karamanakos SN, Argentou M et al (2011) Randomized clinical trial of laparoscopic Roux-en-Y gastric bypass versus laparoscopic sleeve gastrectomy for the management of patients with BMI < 50 kg/m2. Obes Surg 21:1650–1656CrossRefPubMed Kehagias I, Karamanakos SN, Argentou M et al (2011) Randomized clinical trial of laparoscopic Roux-en-Y gastric bypass versus laparoscopic sleeve gastrectomy for the management of patients with BMI < 50 kg/m2. Obes Surg 21:1650–1656CrossRefPubMed
28.
go back to reference Kockerling F, Schug-Pass C (2009) Gastroscopically controlled laparoscopic sleeve gastrectomy. Obes Facts 2(Suppl 1):15–18CrossRefPubMed Kockerling F, Schug-Pass C (2009) Gastroscopically controlled laparoscopic sleeve gastrectomy. Obes Facts 2(Suppl 1):15–18CrossRefPubMed
29.
go back to reference Lacy A, Ibarzabal A, Pando E et al (2010) Revisional surgery after sleeve gastrectomy. Surg Laparosc Endosc Percutan Tech 20:351–356CrossRefPubMed Lacy A, Ibarzabal A, Pando E et al (2010) Revisional surgery after sleeve gastrectomy. Surg Laparosc Endosc Percutan Tech 20:351–356CrossRefPubMed
30.
go back to reference Maher JW, Bakhos W, Nahmias N et al (2009) Drain amylase levels are an adjunct in detection of gastrojejunostomy leaks after Roux-en-Y gastric bypass. J Am Coll Surg 208:881–884 discussion 885–886CrossRefPubMed Maher JW, Bakhos W, Nahmias N et al (2009) Drain amylase levels are an adjunct in detection of gastrojejunostomy leaks after Roux-en-Y gastric bypass. J Am Coll Surg 208:881–884 discussion 885–886CrossRefPubMed
31.
go back to reference Marquez MF, Ayza MF, Lozano RB et al (2010) Gastric leak after laparoscopic sleeve gastrectomy. Obes Surg 20:1306–1311CrossRefPubMed Marquez MF, Ayza MF, Lozano RB et al (2010) Gastric leak after laparoscopic sleeve gastrectomy. Obes Surg 20:1306–1311CrossRefPubMed
32.
go back to reference Martin-Malagon MDA, Rodriguez-Ballester MDL, Arteaga-Gonzalez MDI (2011) Total gastrectomy for failed treatment with endotherapy of chronic gastrocutaneous fistula after sleeve gastrectomy. Surg Obes Relat Dis 7(2):240–242CrossRefPubMed Martin-Malagon MDA, Rodriguez-Ballester MDL, Arteaga-Gonzalez MDI (2011) Total gastrectomy for failed treatment with endotherapy of chronic gastrocutaneous fistula after sleeve gastrectomy. Surg Obes Relat Dis 7(2):240–242CrossRefPubMed
33.
go back to reference Mognol P, Chosidow D, Marmuse JP (2005) Laparoscopic sleeve gastrectomy as an initial bariatric operation for high-risk patients: initial results in 10 patients. Obes Surg 15:1030–1033CrossRefPubMed Mognol P, Chosidow D, Marmuse JP (2005) Laparoscopic sleeve gastrectomy as an initial bariatric operation for high-risk patients: initial results in 10 patients. Obes Surg 15:1030–1033CrossRefPubMed
34.
go back to reference Moy J, Pomp A, Dakin G et al (2008) Laparoscopic sleeve gastrectomy for morbid obesity. Am J Surg 196:e56–e59CrossRefPubMed Moy J, Pomp A, Dakin G et al (2008) Laparoscopic sleeve gastrectomy for morbid obesity. Am J Surg 196:e56–e59CrossRefPubMed
35.
go back to reference Nguyen NT, Nguyen XM, Dholakia C (2010) The use of endoscopic stent in management of leaks after sleeve gastrectomy. Obes Surg 20(9):1289–1292CrossRefPubMed Nguyen NT, Nguyen XM, Dholakia C (2010) The use of endoscopic stent in management of leaks after sleeve gastrectomy. Obes Surg 20(9):1289–1292CrossRefPubMed
36.
go back to reference Papavramidis TS, Kotzampassi K, Kotidis E et al (2008) Endoscopic fibrin sealing of gastrocutaneous fistulas after sleeve gastrectomy and biliopancreatic diversion with duodenal switch. J Gastroenterol Hepatol 23:1802–1805CrossRefPubMed Papavramidis TS, Kotzampassi K, Kotidis E et al (2008) Endoscopic fibrin sealing of gastrocutaneous fistulas after sleeve gastrectomy and biliopancreatic diversion with duodenal switch. J Gastroenterol Hepatol 23:1802–1805CrossRefPubMed
37.
go back to reference Roa PE, Kaidar-Person O, Pinto D et al (2006) Laparoscopic sleeve gastrectomy as treatment for morbid obesity: technique and short-term outcome. Obes Surg 16:1323–1326CrossRefPubMed Roa PE, Kaidar-Person O, Pinto D et al (2006) Laparoscopic sleeve gastrectomy as treatment for morbid obesity: technique and short-term outcome. Obes Surg 16:1323–1326CrossRefPubMed
38.
go back to reference Rosenthal RJ (2012) International sleeve gastrectomy expert panel consensus statement: best practice guidelines based on experience of >12,000 cases. Surg Obes Relat Dis 8:8–19CrossRefPubMed Rosenthal RJ (2012) International sleeve gastrectomy expert panel consensus statement: best practice guidelines based on experience of >12,000 cases. Surg Obes Relat Dis 8:8–19CrossRefPubMed
39.
go back to reference Sanchez-Santos R, Masdevall C, Baltasar A et al (2009) Short- and mid-term outcomes of sleeve gastrectomy for morbid obesity: the experience of the Spanish National Registry. Obes Surg 19:1203–1210CrossRefPubMed Sanchez-Santos R, Masdevall C, Baltasar A et al (2009) Short- and mid-term outcomes of sleeve gastrectomy for morbid obesity: the experience of the Spanish National Registry. Obes Surg 19:1203–1210CrossRefPubMed
40.
go back to reference Serra C, Baltasar A, Andreo L et al (2007) Treatment of gastric leaks with coated self-expanding stents after sleeve gastrectomy. Obes Surg 17:866–872CrossRefPubMed Serra C, Baltasar A, Andreo L et al (2007) Treatment of gastric leaks with coated self-expanding stents after sleeve gastrectomy. Obes Surg 17:866–872CrossRefPubMed
41.
go back to reference Tan JT, Kariyawasam S, Wijeratne T et al (2010) Diagnosis and management of gastric leaks after laparoscopic sleeve gastrectomy for morbid obesity. Obes Surg 20:403–409CrossRefPubMed Tan JT, Kariyawasam S, Wijeratne T et al (2010) Diagnosis and management of gastric leaks after laparoscopic sleeve gastrectomy for morbid obesity. Obes Surg 20:403–409CrossRefPubMed
Metadata
Title
Gastric leaks after sleeve gastrectomy: a multicenter experience with 2,834 patients
Authors
Nasser Sakran
David Goitein
Asnat Raziel
Andrei Keidar
Nahum Beglaibter
Ronit Grinbaum
Ibrahim Matter
Ricardo Alfici
Ahmad Mahajna
Igor Waksman
Mordechai Shimonov
Ahmad Assalia
Publication date
01-01-2013
Publisher
Springer-Verlag
Published in
Surgical Endoscopy / Issue 1/2013
Print ISSN: 0930-2794
Electronic ISSN: 1432-2218
DOI
https://doi.org/10.1007/s00464-012-2426-x

Other articles of this Issue 1/2013

Surgical Endoscopy 1/2013 Go to the issue