Skip to main content
Top
Published in: Surgical Endoscopy 6/2012

01-06-2012

Sleeve gastrectomy and the risk of leak: a systematic analysis of 4,888 patients

Authors: Alexander R. Aurora, Leena Khaitan, Alan A. Saber

Published in: Surgical Endoscopy | Issue 6/2012

Login to get access

Abstract

Introduction

Sleeve gastrectomy has become a popular stand-alone bariatric procedure with comparable weight loss and resolution of comorbidities to that of laparoscopic gastric bypass. The simplicity of the procedure and the decreased long-term risk profile make this surgery more appealing. Nonetheless, the ever present risk of a staple-line leak is still of great concern and needs further investigation.

Methods

An electronic literature search of MEDLINE database plus manual reference checks of articles published on laparoscopic sleeve gastrectomy for morbid obesity and its complications was completed. Keywords used in the search were “sleeve gastrectomy” OR “gastric sleeve” AND “leak.” We analyzed 29 publications, including 4,888 patients. We analyzed the frequency of leak after sleeve gastrectomy and its associated risks of causation.

Results

The risk of leak after sleeve gastrectomy in all comers was 2.4%. This risk was 2.9% in the super-obese [body mass index (BMI) > 50 kg/m2] and 2.2% for BMI < 50 kg/m2. Staple height and use of buttressing material did not affect leak rate. The use of a size 40-Fr or greater bougie was associated with a leak rate of 0.6% compared with those who used smaller sizes whose leak rate was 2.8%. Leaks were found at the proximal third of the stomach in 89% of cases. Most leaks were diagnosed after discharge. Endoscopic management is a viable option for leaks and was documented in 11% of cases as successful.

Conclusions

Sleeve gastrectomy has become an important surgical option for the treatment of the ever growing morbidly obese population. The risk of leak is low at 2.4%. Attention to detail specifically at the esophagogastric junction cannot be stressed enough. Careful patient selection (BMI < 50 kg/m2) and adopting the use of a 40-Fr or larger bougie may decrease the risk of leak. Vigilant follow-up during the first 30 days is critical to avoid catastrophe, because most leaks will happen after patient discharge.
Literature
1.
go back to reference Cottam D, Qureshi FG, Mattar SG, Sharma S, Holover S, Bonanomi G, Ramanathan R, Schauer P (2006) Laparoscopic sleeve gastrectomy as an initial weight-loss procedure for high-risk patients with morbid obesity. Surg Endosc 20:859–863PubMedCrossRef Cottam D, Qureshi FG, Mattar SG, Sharma S, Holover S, Bonanomi G, Ramanathan R, Schauer P (2006) Laparoscopic sleeve gastrectomy as an initial weight-loss procedure for high-risk patients with morbid obesity. Surg Endosc 20:859–863PubMedCrossRef
2.
go back to reference Bohdjalian A, Langer FB, Shakeri-Leidenmühler S, Gfrerer L, Ludvik B, Zacherl J, Prager G (2010) Sleeve gastrectomy as sole and definitive bariatric procedure: 5-year results for weight loss and ghrelin. Obes Surg 20:535–540PubMedCrossRef Bohdjalian A, Langer FB, Shakeri-Leidenmühler S, Gfrerer L, Ludvik B, Zacherl J, Prager G (2010) Sleeve gastrectomy as sole and definitive bariatric procedure: 5-year results for weight loss and ghrelin. Obes Surg 20:535–540PubMedCrossRef
3.
go back to reference Felberbauer FX, Langer F, Shakeri-Manesch S, Schmaldienst E, Kees M, Kriwanek S, Prager M, Prager G (2008) Laparoscopic sleeve gastrectomy as an isolated bariatric procedure: intermediate-term results from a large series in three Austrian centers. Obes Surg 18:814–818PubMedCrossRef Felberbauer FX, Langer F, Shakeri-Manesch S, Schmaldienst E, Kees M, Kriwanek S, Prager M, Prager G (2008) Laparoscopic sleeve gastrectomy as an isolated bariatric procedure: intermediate-term results from a large series in three Austrian centers. Obes Surg 18:814–818PubMedCrossRef
4.
go back to reference Srinivasa S, Hill LS, Sammour T, Hill AG, Babor R, Rahman H (2010) Early and mid-term outcomes of single-stage laparoscopic sleeve gastrectomy. Obes Surg 20:1484–1490PubMedCrossRef Srinivasa S, Hill LS, Sammour T, Hill AG, Babor R, Rahman H (2010) Early and mid-term outcomes of single-stage laparoscopic sleeve gastrectomy. Obes Surg 20:1484–1490PubMedCrossRef
5.
go back to reference Frezza EE, Reddy S, Gee LL, Wachtel MS (2009) Complications after sleeve gastrectomy for morbid obesity. Obes Surg 19:684–687PubMedCrossRef Frezza EE, Reddy S, Gee LL, Wachtel MS (2009) Complications after sleeve gastrectomy for morbid obesity. Obes Surg 19:684–687PubMedCrossRef
6.
go back to reference Stroh C, Birk D, Flade-Kuthe R, Frenken M, Herbig B, Höhne S, Köhler H, Lange V, Ludwig K, Matkowitz R, Meyer G, Pick P, Horbach T, Krause S, Schäfer L, Schlensak M, Shang E, Sonnenberg T, Susewind M, Voigt H, Weiner R, Wolff S, Wolf AM, Schmidt U, Lippert H, Manger T; Bariatric Surgery Working Group (2009) Results of sleeve gastrectomy—data from a nationwide survey on bariatric surgery in Germany. Obes Surg 19:632–640 Stroh C, Birk D, Flade-Kuthe R, Frenken M, Herbig B, Höhne S, Köhler H, Lange V, Ludwig K, Matkowitz R, Meyer G, Pick P, Horbach T, Krause S, Schäfer L, Schlensak M, Shang E, Sonnenberg T, Susewind M, Voigt H, Weiner R, Wolff S, Wolf AM, Schmidt U, Lippert H, Manger T; Bariatric Surgery Working Group (2009) Results of sleeve gastrectomy—data from a nationwide survey on bariatric surgery in Germany. Obes Surg 19:632–640
7.
go back to reference Sánchez-Santos R, Masdevall C, Baltasar A, Martínez-Blázquez C, Ruiz García, de Gordejuela A, Ponsi E, Sánchez-Pernaute A, Vesperinas G, Del Castillo D, Bombuy E, Durán-Escribano C, Ortega L, Ruiz de Adana JC, Baltar J, Maruri I, García-Blázquez E, Torres A (2009) Short- and mid-term outcomes of sleeve gastrectomy for morbid obesity: the experience of the Spanish National Registry. Obes Surg 19:1203–1210PubMedCrossRef Sánchez-Santos R, Masdevall C, Baltasar A, Martínez-Blázquez C, Ruiz García, de Gordejuela A, Ponsi E, Sánchez-Pernaute A, Vesperinas G, Del Castillo D, Bombuy E, Durán-Escribano C, Ortega L, Ruiz de Adana JC, Baltar J, Maruri I, García-Blázquez E, Torres A (2009) Short- and mid-term outcomes of sleeve gastrectomy for morbid obesity: the experience of the Spanish National Registry. Obes Surg 19:1203–1210PubMedCrossRef
8.
go back to reference Bellanger DE, Greenway FL (2011) Laparoscopic sleeve gastrectomy, 529 cases without a leak: short-term results and technical considerations. Obes Surg 21:146–150PubMedCrossRef Bellanger DE, Greenway FL (2011) Laparoscopic sleeve gastrectomy, 529 cases without a leak: short-term results and technical considerations. Obes Surg 21:146–150PubMedCrossRef
9.
go back to reference Chowbey PK, Dhawan K, Khullar R, Sharma A, Soni V, Baijal M, Mittal T (2010) Laparoscopic sleeve gastrectomy: an Indian experience - surgical technique and early results. Obes Surg 20:1340–1347PubMedCrossRef Chowbey PK, Dhawan K, Khullar R, Sharma A, Soni V, Baijal M, Mittal T (2010) Laparoscopic sleeve gastrectomy: an Indian experience - surgical technique and early results. Obes Surg 20:1340–1347PubMedCrossRef
10.
go back to reference Lee CM, Cirangle PT, Jossart GH (2007) Vertical gastrectomy for morbid obesity in 216 patients: report of 2-year results. Surg Endosc 21:1810–1816PubMedCrossRef Lee CM, Cirangle PT, Jossart GH (2007) Vertical gastrectomy for morbid obesity in 216 patients: report of 2-year results. Surg Endosc 21:1810–1816PubMedCrossRef
11.
go back to reference Weiner RA, Weiner S, Pomhoff I, Jacobi C, Makarewicz W, Weigand G (2007) Laparoscopic sleeve gastrectomy: influence of sleeve size and resected gastric volume. Obes Surg 17:1297–1305PubMedCrossRef Weiner RA, Weiner S, Pomhoff I, Jacobi C, Makarewicz W, Weigand G (2007) Laparoscopic sleeve gastrectomy: influence of sleeve size and resected gastric volume. Obes Surg 17:1297–1305PubMedCrossRef
12.
go back to reference Johnston D, Dachtler J, Sue-Ling HM, King RF, Martin G (2003) The Magenstrasse and Mill operation for morbid obesity. Obes Surg 13:10–16PubMedCrossRef Johnston D, Dachtler J, Sue-Ling HM, King RF, Martin G (2003) The Magenstrasse and Mill operation for morbid obesity. Obes Surg 13:10–16PubMedCrossRef
13.
go back to reference Dapri G, Cadière GB, Himpens J (2010) Reinforcing the staple line during laparoscopic sleeve gastrectomy: prospective randomized clinical study comparing three different techniques. Obes Surg 20:462–467PubMedCrossRef Dapri G, Cadière GB, Himpens J (2010) Reinforcing the staple line during laparoscopic sleeve gastrectomy: prospective randomized clinical study comparing three different techniques. Obes Surg 20:462–467PubMedCrossRef
14.
go back to reference Elariny H, González H, Wang B (2005) Tissue thickness of human stomach measured on excised gastric specimens from obese patients. Surg Tech Int 14:119–124 Elariny H, González H, Wang B (2005) Tissue thickness of human stomach measured on excised gastric specimens from obese patients. Surg Tech Int 14:119–124
15.
go back to reference Oshiro T, Kasama K, Umezawa A, Kanehira E, Kurokawa Y (2010) Successful management of refractory staple line leakage at the esophagogastric junction after a sleeve gastrectomy using the HANAROSTENT. Obes Surg 20:530–534PubMedCrossRef Oshiro T, Kasama K, Umezawa A, Kanehira E, Kurokawa Y (2010) Successful management of refractory staple line leakage at the esophagogastric junction after a sleeve gastrectomy using the HANAROSTENT. Obes Surg 20:530–534PubMedCrossRef
16.
go back to reference Fuks D, Verhaeghe P, Brehant O, Sabbagh C, Dumont F, Riboulot M, Delcenserie R, Regimbeau JM (2009) Results of laparoscopic sleeve gastrectomy: a prospective study in 135 patients with morbid obesity. Surgery 145:106–113PubMedCrossRef Fuks D, Verhaeghe P, Brehant O, Sabbagh C, Dumont F, Riboulot M, Delcenserie R, Regimbeau JM (2009) Results of laparoscopic sleeve gastrectomy: a prospective study in 135 patients with morbid obesity. Surgery 145:106–113PubMedCrossRef
17.
go back to reference Moon Han S, Kim WW, Oh JH (2005) Results of laparoscopic sleeve gastrectomy (LSG) at 1 year in morbidly obese Korean patients. Obes Surg 15:1469–1475PubMedCrossRef Moon Han S, Kim WW, Oh JH (2005) Results of laparoscopic sleeve gastrectomy (LSG) at 1 year in morbidly obese Korean patients. Obes Surg 15:1469–1475PubMedCrossRef
18.
go back to reference Roa PE, Kaidar-Person O, Pinto D, Cho M, Szomstein S, Rosenthal RJ (2006) Laparoscopic sleeve gastrectomy as treatment for morbid obesity: technique and short term outcome. Obes Surg 16:1323–1326PubMedCrossRef Roa PE, Kaidar-Person O, Pinto D, Cho M, Szomstein S, Rosenthal RJ (2006) Laparoscopic sleeve gastrectomy as treatment for morbid obesity: technique and short term outcome. Obes Surg 16:1323–1326PubMedCrossRef
19.
go back to reference Lalor PF, Tucker ON, Szomstein S, Rosenthal RJ (2008) Complications after laparoscopic sleeve gastrectomy. Surg Obes Relat Dis 4:33–38PubMedCrossRef Lalor PF, Tucker ON, Szomstein S, Rosenthal RJ (2008) Complications after laparoscopic sleeve gastrectomy. Surg Obes Relat Dis 4:33–38PubMedCrossRef
20.
go back to reference Nocca D, Krawczykowsky D, Bomans B, Noël P, Picot MC, Blanc PM, de Hons C, Millat B, Gagner M, Monnier L, Fabre JM (2008) A prospective multicenter study of 163 sleeve gastrectomies: results at 1 and 2 years. Obes Surg 18:560–565PubMedCrossRef Nocca D, Krawczykowsky D, Bomans B, Noël P, Picot MC, Blanc PM, de Hons C, Millat B, Gagner M, Monnier L, Fabre JM (2008) A prospective multicenter study of 163 sleeve gastrectomies: results at 1 and 2 years. Obes Surg 18:560–565PubMedCrossRef
21.
go back to reference Kasalicky M, Michalsky D, Housova J, Haluzik M, Housa D, Haluzikova D, Fried M (2008) Laparoscopic sleeve gastrectomy without an over-sewing of the staple line. Obes Surg 18:1257–1262PubMedCrossRef Kasalicky M, Michalsky D, Housova J, Haluzik M, Housa D, Haluzikova D, Fried M (2008) Laparoscopic sleeve gastrectomy without an over-sewing of the staple line. Obes Surg 18:1257–1262PubMedCrossRef
22.
go back to reference Mui WL, Ng EK, Tsung BY, Lam CC, Yung MY (2008) Laparoscopic sleeve gastrectomy in ethnic obese Chinese. Obes Surg 18:1571–1574PubMedCrossRef Mui WL, Ng EK, Tsung BY, Lam CC, Yung MY (2008) Laparoscopic sleeve gastrectomy in ethnic obese Chinese. Obes Surg 18:1571–1574PubMedCrossRef
23.
go back to reference Rubin M, Yehoshua RT, Stein M, Lederfein D, Fichman S, Bernstine H, Eidelman LA (2008) Laparoscopic sleeve gastrectomy with minimal morbidity. Early results in 120 morbidly obese patients. Obes Surg 18:1567–1570PubMedCrossRef Rubin M, Yehoshua RT, Stein M, Lederfein D, Fichman S, Bernstine H, Eidelman LA (2008) Laparoscopic sleeve gastrectomy with minimal morbidity. Early results in 120 morbidly obese patients. Obes Surg 18:1567–1570PubMedCrossRef
24.
go back to reference Skrekas G, Lapatsanis D, Stafyla V, Papalambros A (2008) One year after laparoscopic “tight” sleeve gastrectomy: technique and outcome. Obes Surg 18:810–813PubMedCrossRef Skrekas G, Lapatsanis D, Stafyla V, Papalambros A (2008) One year after laparoscopic “tight” sleeve gastrectomy: technique and outcome. Obes Surg 18:810–813PubMedCrossRef
25.
go back to reference Burgos AM, Braghetto I, Csendes A, Maluenda F, Korn O, Yarmuch J, Gutierrez L (2009) Gastric leak after laparoscopic-sleeve gastrectomy for obesity. Obes Surg 19:1672–1677PubMedCrossRef Burgos AM, Braghetto I, Csendes A, Maluenda F, Korn O, Yarmuch J, Gutierrez L (2009) Gastric leak after laparoscopic-sleeve gastrectomy for obesity. Obes Surg 19:1672–1677PubMedCrossRef
26.
go back to reference Goitein D, Goitein O, Feigin A, Zippel D, Papa M (2009) Sleeve gastrectomy: radiologic patterns after surgery. Surg Endosc 23:1559–1563PubMedCrossRef Goitein D, Goitein O, Feigin A, Zippel D, Papa M (2009) Sleeve gastrectomy: radiologic patterns after surgery. Surg Endosc 23:1559–1563PubMedCrossRef
27.
go back to reference Kakoulidis TP, Karringer A, Gloaguen T, Arvidsson D (2009) Initial results with sleeve gastrectomy for patients with class I obesity (BMI 30–35 kg/m2. Surg Obes Relat Dis 5:425–428PubMedCrossRef Kakoulidis TP, Karringer A, Gloaguen T, Arvidsson D (2009) Initial results with sleeve gastrectomy for patients with class I obesity (BMI 30–35 kg/m2. Surg Obes Relat Dis 5:425–428PubMedCrossRef
28.
go back to reference Menenakos E, Stamou KM, Albanopoulos K, Papailiou J, Theodorou D, Leandros E (2010) Laparoscopic sleeve gastrectomy performed with intent to treat morbid obesity: a prospective single-center study of 261 patients with a median follow-up of 1 year. Obes Surg 20:276–282PubMedCrossRef Menenakos E, Stamou KM, Albanopoulos K, Papailiou J, Theodorou D, Leandros E (2010) Laparoscopic sleeve gastrectomy performed with intent to treat morbid obesity: a prospective single-center study of 261 patients with a median follow-up of 1 year. Obes Surg 20:276–282PubMedCrossRef
29.
go back to reference Armostrong J, O’Malley SP (2010) Outcomes of sleeve gastrectomy for morbid obesity: a safe and effective procedure. Int J Surg 8:69–71CrossRef Armostrong J, O’Malley SP (2010) Outcomes of sleeve gastrectomy for morbid obesity: a safe and effective procedure. Int J Surg 8:69–71CrossRef
30.
go back to reference Csendes A, Braghetto I, León P, Burgos AM (2010) Management of leaks after laparoscopic sleeve gastrectomy in patients with obesity. J Gastrointest Surg 14:1343–1348PubMedCrossRef Csendes A, Braghetto I, León P, Burgos AM (2010) Management of leaks after laparoscopic sleeve gastrectomy in patients with obesity. J Gastrointest Surg 14:1343–1348PubMedCrossRef
31.
go back to reference Lacy A, Ibarzabal A, Pando E, Adelsdorfer C, Delitala A, Corcelles R, Delgado S, Vidal J (2010) Revisional surgery after sleeve gastrectomy. Surg Laparosc Endosc Percutan Tech 20:351–356PubMedCrossRef Lacy A, Ibarzabal A, Pando E, Adelsdorfer C, Delitala A, Corcelles R, Delgado S, Vidal J (2010) Revisional surgery after sleeve gastrectomy. Surg Laparosc Endosc Percutan Tech 20:351–356PubMedCrossRef
32.
go back to reference Ser KH, Lee WJ, Lee YC, Chen JC, Su YH, Chen SC (2010) Experience in laparoscopic sleeve gastrectomy for morbidly obese Taiwanese: staple-line reinforcement is important for preventing leakage. Surg Endosc 24:2253–2259PubMedCrossRef Ser KH, Lee WJ, Lee YC, Chen JC, Su YH, Chen SC (2010) Experience in laparoscopic sleeve gastrectomy for morbidly obese Taiwanese: staple-line reinforcement is important for preventing leakage. Surg Endosc 24:2253–2259PubMedCrossRef
33.
go back to reference Casella G, Soricelli E, Rizzello M, Trentino P, Fiocca F, Fantini A, Salvatori FM, Basso N (2009) Nonsurgical treatment of staple line leaks after laparoscopic sleeve gastrectomy. Obes Surg 19:821–826PubMedCrossRef Casella G, Soricelli E, Rizzello M, Trentino P, Fiocca F, Fantini A, Salvatori FM, Basso N (2009) Nonsurgical treatment of staple line leaks after laparoscopic sleeve gastrectomy. Obes Surg 19:821–826PubMedCrossRef
Metadata
Title
Sleeve gastrectomy and the risk of leak: a systematic analysis of 4,888 patients
Authors
Alexander R. Aurora
Leena Khaitan
Alan A. Saber
Publication date
01-06-2012
Publisher
Springer-Verlag
Published in
Surgical Endoscopy / Issue 6/2012
Print ISSN: 0930-2794
Electronic ISSN: 1432-2218
DOI
https://doi.org/10.1007/s00464-011-2085-3

Other articles of this Issue 6/2012

Surgical Endoscopy 6/2012 Go to the issue