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Surgical Endoscopy

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01-01-2013

Laparoscopic versus open surgery for rectal cancer: results of a prospective multicentre analysis of 4,970 patients

Authors: J. Lujan, G. Valero, S. Biondo, E. Espin, P. Parrilla, H. Ortiz

Published in: Surgical Endoscopy | Issue 1/2013

Abstract

Objective

To compare laparoscopic versus open surgery for rectal cancer and analyse the results of the multidisciplinary audited project on total mesorectal excision conducted in Spain.

Background

The safety and therapeutic efficiency of laparoscopic surgery for rectal cancer are controversial due to the technical difficulties it involves. A deviation from the oncological principles of mesorectal excision would mean a potential increase in local recurrence and shorter survival.

Methods

This prospective non-randomised multicentre study includes 4,970 patients with rectal cancer. The study compares perioperative, postoperative, anatomicopathological and survival variables.

Results

Five hundred and sixty five patients were excluded. Of the remaining 4,405, 3,018 (68.51 %) had open surgery (OS) and 1,387 (31.49 %) laparoscopic surgery (LS). The rate of anterior resections was higher in the LS group. The rate of intraoperative tumour perforation, number of red blood cell concentrates transfused and length of hospital stay were greater in the OS group, whereas surgical time was longer in the LS group. The incidence of complications was 45.6 % in the OS group and 38.3 % in the LS group. Involvement of the circumferential and distal margin, as well as unsatisfactory and partially satisfactory quality of the mesorectum, were greater in the OS group. There were no differences for local recurrence and survival rates.

Conclusions

According to these results, laparoscopic surgery is the best option for the surgical treatment of rectal cancer, with similar rates of local recurrence and survival, although there are oncological indicators in this study to suggest that these results can be improved with laparoscopic surgery.

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Title: Laparoscopic versus open surgery for rectal cancer: results of a prospective multicentre analysis of 4,970 patients
Authors: J. Lujan
G. Valero
S. Biondo
E. Espin
P. Parrilla
H. Ortiz
Publication date: 01-01-2013
Publisher: Springer-Verlag
Published in: Surgical Endoscopy / Issue 1/2013
Print ISSN: 0930-2794
Electronic ISSN: 1432-2218
DOI: https://doi.org/10.1007/s00464-012-2444-8

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Laparoscopic versus open surgery for rectal cancer: results of a prospective multicentre analysis of 4,970 patients

Abstract

Objective

Background

Methods

Results

Conclusions

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Objective

Background

Methods

Results

Conclusions

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