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01-06-2015 | Original Article

25-hydroxyvitamin D serum level in children of different ethnicity living in Italy

Authors: Bruna Franchi, Michele Piazza, Marco Sandri, Laura Tenero, Pasquale Comberiati, Attilio Loris Boner, Carlo Capristo

Published in: European Journal of Pediatrics | Issue 6/2015

Abstract

Several factors including ethnicity are known to influence 25(OH)D levels. The purpose of our study was to assess 25(OH)D levels among 1374 pediatric subjects of different ethnicity and to determine the prevalence of vitamin D deficiency and insufficiency among different ethnic groups. The prevalence of 25(OH)D ≤20 ng/ml was 44.2, 65.2, 69.2, 54.0, and 44.8 % among Caucasians, Africans, North Africans, Indians, and others, respectively (P < 0.001). The median of 25(OH)D was 21.0 ng/ml (IQR = 14.0–29.6 ng/ml) for the cohort. Season of blood sampling, age, ethnicity, gestational age, birth weight, and z-score BMI were associated with 25(OH)D levels. Caucasians had higher median 25(OH)D levels than sub-Saharan Africans (P < 0.001), North Africans (P < 0.001), and Indians (P < 0.001). There were no significant differences in the median 25(OH)D levels between ethnic groups among infants, whereas for children older than 1 year we found significant differences in 25(OH)D levels in the different ethnic groups, compared to Caucasians.

Conclusion: Ethnicity was correlated with 25(OH)D levels among children older than 1 year. We found a high prevalence of vitamin D deficiency and insufficiency after the first year of life, and this was more remarkable in non-Caucasian children.

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Title: 25-hydroxyvitamin D serum level in children of different ethnicity living in Italy
Authors: Bruna Franchi
Michele Piazza
Marco Sandri
Laura Tenero
Pasquale Comberiati
Attilio Loris Boner
Carlo Capristo
Publication date: 01-06-2015
Publisher: Springer Berlin Heidelberg
Published in: European Journal of Pediatrics / Issue 6/2015
Print ISSN: 0340-6199
Electronic ISSN: 1432-1076
DOI: https://doi.org/10.1007/s00431-014-2451-y

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25-hydroxyvitamin D serum level in children of different ethnicity living in Italy

Abstract

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