Published in:
01-06-2008
Vitamin D deficiency in children and adolescents: Epidemiology, impact and treatment
Authors:
Susanna Y. Huh, Catherine M. Gordon
Published in:
Reviews in Endocrine and Metabolic Disorders
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Issue 2/2008
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Abstract
Vitamin D deficiency is highly prevalent among children and adolescents worldwide. The high rates of vitamin D deficiency during childhood are of major public health relevance, given the growing evidence that vitamin D deficiency may play a key role in the pathophysiology of many chronic diseases beyond rickets, including autoimmune conditions, cardiovascular diseases, and cancer. Identification, treatment, and prevention of vitamin D deficiency in childhood may therefore have profound health effects throughout the life span. In this review, we discuss the definitions, epidemiology, clinical implications, and treatment of vitamin D deficiency in children and adolescents.