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01-06-2019 | Forensic Medicine

A systematic review of the agreement between chronological age and skeletal age based on the Greulich and Pyle atlas

Authors: Pål Skage Dahlberg, Annhild Mosdøl, Yunpeng Ding, Øyvind Bleka, Veslemøy Rolseth, Gyri Hval Straumann, Marianne Skjerven-Martinsen, Gerd Jorunn Møller Delaveris, Gunn Elisabeth Vist

Published in: European Radiology | Issue 6/2019

Abstract

Objectives

This systematic review examines the agreement between assessed skeletal age by the Greulich and Pyle atlas (GP skeletal age) and chronological age.

Methods

We searched electronic databases until January 2017 for studies reporting GP skeletal age and confirmed chronological age in healthy individuals aged 10–25 years. Results are presented as forest plots and meta-analyses (random-effects models).

Results

In separate meta-analyses for each age group and sex (14–18 years for girls, 14–19 years for boys), the pooled mean differences between GP skeletal age and chronological age varied from -0.52 years to 0.47 years. In individual studies, age group and sex-specific mean differences between GP skeletal age and chronological age rarely exceeded 1 year, but between-study heterogeneities were large in most age groups. Few studies examined mean chronological age and distribution for each GP skeletal age. One study of good methodological quality indicates that 95% prediction intervals for chronological age from given GP skeletal ages are typically around 4 years.

Conclusions

There is still good correlation between GP skeletal age and mean chronological age in modern populations. However, the individual variation of development within a population and heterogeneities between studies are substantial.

Key Points

• The GP atlas still corresponds well with mean chronological age in modern populations.

• The substantial variation within a population must be considered.

• The heterogeneity between studies is relatively large and of unknown origin.

Available only for authorised users

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Title: A systematic review of the agreement between chronological age and skeletal age based on the Greulich and Pyle atlas
Authors: Pål Skage Dahlberg
Annhild Mosdøl
Yunpeng Ding
Øyvind Bleka
Veslemøy Rolseth
Gyri Hval Straumann
Marianne Skjerven-Martinsen
Gerd Jorunn Møller Delaveris
Gunn Elisabeth Vist
Publication date: 01-06-2019
Publisher: Springer Berlin Heidelberg
Published in: European Radiology / Issue 6/2019
Print ISSN: 0938-7994
Electronic ISSN: 1432-1084
DOI: https://doi.org/10.1007/s00330-018-5718-2

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Springer Medicine

A systematic review of the agreement between chronological age and skeletal age based on the Greulich and Pyle atlas

Abstract

Objectives

Methods

Results

Conclusions

Key Points

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Objectives

Methods

Results

Conclusions

Key Points

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