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01-07-2016 | Magnetic Resonance

Cardiac index after acute ST-segment elevation myocardial infarction measured with phase-contrast cardiac magnetic resonance imaging

Authors: Gert Klug, Sebastian Johannes Reinstadler, Hans-Josef Feistritzer, Christian Kremser, Johannes P. Schwaiger, Martin Reindl, Johannes Mair, Silvana Müller, Agnes Mayr, Wolfgang-Michael Franz, Bernhard Metzler

Published in: European Radiology | Issue 7/2016

Abstract

Objectives

Phase-contrast CMR (PC-CMR) might provide a fast and robust non-invasive determination of left ventricular function in patients after ST-segment elevation myocardial infarction (STEMI).

Methods

Cine sequences in the left-ventricular (LV) short-axis and free-breathing, retrospectively gated PC-CMR were performed in 90 patients with first acute STEMI and 15 healthy volunteers. Inter- and intra-observer agreement was determined. The correlations of clinical variables (age, gender, ejection fraction, NT pro-brain natriuretic peptide [NT-proBNP] with cardiac index (CI) were calculated.

Results

For CI, there was a strong agreement of cine CMR with PC-CMR in healthy volunteers (r: 0.82, mean difference: -0.14 l/min/m², error ± 23 %). Agreement was lower in STEMI patients (r: 0.61, mean difference: -0.17 l/min/m², error ± 32 %). In STEMI patients, CI measured with PC-CMR showed lower intra-observer (1 % vs. 9 %) and similar inter-observer variability (9 % vs. 12 %) compared to cine CMR. CI was significantly correlated with age, ejection fraction and NT-proBNP values in STEMI patients.

Discussion

The agreement of PC-CMR and cine CMR for the determination of CI is lower in STEMI patients than in healthy volunteers. After acute STEMI, CI measured with PC-CMR decreases with age, LV ejection fraction and higher NT-proBNP.

Key Points

• Cine CMR and PC-CMR correlate well in healthy volunteers.

• Agreement is lower in STEMI patients.

• Cardiac Output should be measured with one method longitudinally.

• Cardiac output decreases with age after myocardial infarction.

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Title: Cardiac index after acute ST-segment elevation myocardial infarction measured with phase-contrast cardiac magnetic resonance imaging
Authors: Gert Klug
Sebastian Johannes Reinstadler
Hans-Josef Feistritzer
Christian Kremser
Johannes P. Schwaiger
Martin Reindl
Johannes Mair
Silvana Müller
Agnes Mayr
Wolfgang-Michael Franz
Bernhard Metzler
Publication date: 01-07-2016
Publisher: Springer Berlin Heidelberg
Published in: European Radiology / Issue 7/2016
Print ISSN: 0938-7994
Electronic ISSN: 1432-1084
DOI: https://doi.org/10.1007/s00330-015-4022-7

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Cardiac index after acute ST-segment elevation myocardial infarction measured with phase-contrast cardiac magnetic resonance imaging

Abstract

Objectives

Methods

Results

Discussion

Key Points

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Objectives

Methods

Results

Discussion

Key Points

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