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01-09-2020 | Review

Abdominal CT manifestations of adverse events to immunotherapy: a primer for radiologists

Authors: Ali Pourvaziri, Anushri Parakh, Pierpaolo Biondetti, Dushyant Sahani, Avinash Kambadakone

Published in: Abdominal Radiology | Issue 9/2020

Abstract

Immunotherapy is a rapidly growing field within oncology and is being increasingly used in the management of several malignancies. Due to their unique mechanism of action on the immune system and neoplastic cells, the response pattern and adverse events of this novel therapy are distinct from conventional systemic therapies. Accordingly, the imaging appearances following immunotherapy including adverse events are unique and at times perplexing. Imaging is integral to management of patients on immunotherapeutic agents and a thorough understanding of its mechanism, response patterns and adverse events is crucial for precise interpretation of imaging studies. This review provides a description of the mechanism of action of current immunotherapeutic agents and the organ-wise description of their side effects.

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Title: Abdominal CT manifestations of adverse events to immunotherapy: a primer for radiologists
Authors: Ali Pourvaziri
Anushri Parakh
Pierpaolo Biondetti
Dushyant Sahani
Avinash Kambadakone
Publication date: 01-09-2020
Publisher: Springer US
Published in: Abdominal Radiology / Issue 9/2020
Print ISSN: 2366-004X
Electronic ISSN: 2366-0058
DOI: https://doi.org/10.1007/s00261-020-02531-5

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Illustration of figure on mountain summit/© Orapun / Stock.adobe.com, STEP AAG HeroTeaserCollection image/© Tarek / Generated with AI / Stock.adobe.com, ACC 2024 Pediatric and Congenital Heart Disease: Year in Review/© 2024 American College of Cardiology, ACC 2024 Pulmonary Vascular Disease: Year in Review/© 2024 American College of Cardiology, ACC 2024 Valvular Heart Disease: Year in Review/© 2024 American College of Cardiology, ACC 2024 HF and Cardiomyopathies: Year in Review/© 2024 American College of Cardiology, Woman out walking/© Seventyfour / stock.adobe.com (symbolic image with model), Woman checking smartwatch /© saltdium / stock.adobe.com (symbolic image with model), Cardiac catheterization/© Damian / stock.adobe.com

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