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Published in: Osteoporosis International 8/2022

Open Access 24-03-2022 | Care | Review

Post-fracture care programs for prevention of subsequent fragility fractures: a literature assessment of current trends

Authors: K.E. Åkesson, K. Ganda, C. Deignan, M.K. Oates, A. Volpert, K. Brooks, D. Lee, D.R. Dirschl, A.J. Singer

Published in: Osteoporosis International | Issue 8/2022

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Abstract

Post-fracture care (PFC) programs evaluate and manage patients with a minimal trauma or fragility fracture to prevent subsequent fractures. We conducted a literature review to understand current trends in PFC publications, evaluate key characteristics of PFC programs, and assess their clinical effectiveness, geographic variations, and cost-effectiveness. We performed a search for peer-reviewed articles published between January 2003 and December 2020 listed in PubMed or Google Scholar. We categorized identified articles into 4 non-mutually exclusive PFC subtopics based on keywords and abstract content: PFC Types, PFC Effectiveness/Success, PFC Geography, and PFC Economics. The literature search identified 784 eligible articles. Most articles fit into multiple PFC subtopics (PFC Types, 597; PFC Effectiveness/Success, 579; PFC Geography, 255; and PFC Economics, 98). The number of publications describing how PFC programs can improve osteoporosis treatment rates has markedly increased since 2003; however, publication gaps remain, including low numbers of publications from some countries with reported high rates of osteoporosis and/or hip fractures. Fracture liaison services and geriatric/orthogeriatric services were the most common models of PFC programs, and both were shown to be cost-effective. We identified a need to expand and refine PFC programs and to standardize patient identification and reporting on quality improvement measures. Although there is an increasing awareness of the importance of PFC programs, publication gaps remain in most countries. Improvements in established PFC programs and implementation of new PFC programs are still needed to enhance equitable patient care to prevent occurrence of subsequent fractures.
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Literature
2.
go back to reference National Institute of Health (2001) Osteoporosis prevention, diagnosis, and therapy. NIH Consensus Development Panel on Osteoporosis Prevention, Diagnosis, and Therapy. JAMA 285:785–795 National Institute of Health (2001) Osteoporosis prevention, diagnosis, and therapy. NIH Consensus Development Panel on Osteoporosis Prevention, Diagnosis, and Therapy. JAMA 285:785–795
4.
go back to reference Johnell O, Kanis JA (2006) An estimate of the worldwide prevalence and disability associated with osteoporotic fractures. Osteoporos Int 17:1726–1733PubMedCrossRef Johnell O, Kanis JA (2006) An estimate of the worldwide prevalence and disability associated with osteoporotic fractures. Osteoporos Int 17:1726–1733PubMedCrossRef
5.
go back to reference GBD 2019 Fracture Collaborators (2021) Global, regional, and national burden of bone fractures in 204 countries and territories, 1990-2019: a systematic analysis from the Global Burden of Disease Study 2019. Lancet Healthy Longev 2:e580–e592CrossRef GBD 2019 Fracture Collaborators (2021) Global, regional, and national burden of bone fractures in 204 countries and territories, 1990-2019: a systematic analysis from the Global Burden of Disease Study 2019. Lancet Healthy Longev 2:e580–e592CrossRef
6.
go back to reference Lewiecki EM, Ortendahl JD, Vanderpuye-Orgle J, Grauer A, Arellano J, Lemay J, Harmon AL, Broder MS, Singer AJ (2019) Healthcare policy changes in osteoporosis can improve outcomes and reduce costs in the United States. JBMR Plus 3:e10192PubMedPubMedCentralCrossRef Lewiecki EM, Ortendahl JD, Vanderpuye-Orgle J, Grauer A, Arellano J, Lemay J, Harmon AL, Broder MS, Singer AJ (2019) Healthcare policy changes in osteoporosis can improve outcomes and reduce costs in the United States. JBMR Plus 3:e10192PubMedPubMedCentralCrossRef
7.
go back to reference Ganda K, Mitchell PJ, Seibel MJ (2019) Models of secondary fracture prevention. In: Siebel MJ, Mitchell PJ (eds) Secondary fracture prevention: an international perspective. Academic Press, London, pp 33–62CrossRef Ganda K, Mitchell PJ, Seibel MJ (2019) Models of secondary fracture prevention. In: Siebel MJ, Mitchell PJ (eds) Secondary fracture prevention: an international perspective. Academic Press, London, pp 33–62CrossRef
8.
go back to reference Grigoryan KV, Javedan H, Rudolph JL (2014) Orthogeriatric care models and outcomes in hip fracture patients: a systematic review and meta-analysis. J Orthop Trauma 28:e49–e55PubMedPubMedCentralCrossRef Grigoryan KV, Javedan H, Rudolph JL (2014) Orthogeriatric care models and outcomes in hip fracture patients: a systematic review and meta-analysis. J Orthop Trauma 28:e49–e55PubMedPubMedCentralCrossRef
9.
go back to reference Schweser KM, Crist BD, Nguyen VH (2017) Combined orthogeriatric and fracture liaison service for improved postfracture patient care. Osteoporos Sarcopenia 3:159PubMedPubMedCentralCrossRef Schweser KM, Crist BD, Nguyen VH (2017) Combined orthogeriatric and fracture liaison service for improved postfracture patient care. Osteoporos Sarcopenia 3:159PubMedPubMedCentralCrossRef
10.
go back to reference Naranjo A, Fernández-Conde S, Ojeda S, Torres-Hernández L, Hernández-Carballo C, Bernardos I, Rodríguez S, Laynez P (2017) Preventing future fractures: effectiveness of an orthogeriatric fracture liaison service compared to an outpatient fracture liaison service and the standard management in patients with hip fracture. Arch Osteoporos 12:112PubMedCrossRef Naranjo A, Fernández-Conde S, Ojeda S, Torres-Hernández L, Hernández-Carballo C, Bernardos I, Rodríguez S, Laynez P (2017) Preventing future fractures: effectiveness of an orthogeriatric fracture liaison service compared to an outpatient fracture liaison service and the standard management in patients with hip fracture. Arch Osteoporos 12:112PubMedCrossRef
11.
go back to reference Schray D, Neuerburg C, Stein J, Gosch M, Schieker M, Böcker W, Kammerlander C (2016) Value of a coordinated management of osteoporosis via fracture liaison service for the treatment of orthogeriatric patients. Eur J Trauma Emerg Surg 42:559–564PubMedCrossRef Schray D, Neuerburg C, Stein J, Gosch M, Schieker M, Böcker W, Kammerlander C (2016) Value of a coordinated management of osteoporosis via fracture liaison service for the treatment of orthogeriatric patients. Eur J Trauma Emerg Surg 42:559–564PubMedCrossRef
12.
go back to reference Borade A, Kempegowda H, Tawari A, Suk M, Horwitz DS (2016) Improvement in osteoporosis detection in a fracture liaison service with integration of a geriatric hip fracture care program. Injury 47:2755–2759PubMedCrossRef Borade A, Kempegowda H, Tawari A, Suk M, Horwitz DS (2016) Improvement in osteoporosis detection in a fracture liaison service with integration of a geriatric hip fracture care program. Injury 47:2755–2759PubMedCrossRef
13.
go back to reference Carlson BC, Robinson WA, Wanderman NR, Nassr AN, Huddleston PM 3rd, Yaszemski MJ, Currier BL, Jeray KJ, Kirk KL, Bunta AD, Murphy S, Patel B, Watkins CM, Sietsema DL, Edwards BJ, Tosi LL, Anderson PA, Freedman BA (2018) The American Orthopaedic Association's Own the Bone® database: a national quality improvement project for the treatment of bone health in fragility fracture patients. Osteoporos Int 29:2101–2109PubMedCrossRef Carlson BC, Robinson WA, Wanderman NR, Nassr AN, Huddleston PM 3rd, Yaszemski MJ, Currier BL, Jeray KJ, Kirk KL, Bunta AD, Murphy S, Patel B, Watkins CM, Sietsema DL, Edwards BJ, Tosi LL, Anderson PA, Freedman BA (2018) The American Orthopaedic Association's Own the Bone® database: a national quality improvement project for the treatment of bone health in fragility fracture patients. Osteoporos Int 29:2101–2109PubMedCrossRef
14.
go back to reference Mackey PA, Rosenthal LD, Mi L, Whitaker MD (2019) Subsequent fracture prevention in patients 50 years and older with fragility fractures: a quality improvement initiative. J Healthc Qual 41:17–22PubMedCrossRef Mackey PA, Rosenthal LD, Mi L, Whitaker MD (2019) Subsequent fracture prevention in patients 50 years and older with fragility fractures: a quality improvement initiative. J Healthc Qual 41:17–22PubMedCrossRef
15.
go back to reference Holzmueller CG, Karp S, Zeldow D, Lee DB, Thompson DA (2016) Development of a cloud-based application for the fracture liaison service model of care. Osteoporos Int 27:683–690PubMedCrossRef Holzmueller CG, Karp S, Zeldow D, Lee DB, Thompson DA (2016) Development of a cloud-based application for the fracture liaison service model of care. Osteoporos Int 27:683–690PubMedCrossRef
16.
go back to reference Gupta MJ, Shah S, Peterson S, Baim S (2018) Rush Fracture Liaison Service for capturing “missed opportunities” to treat osteoporosis in patients with fragility fractures. Osteoporos Int 29:1861–1874PubMedCrossRef Gupta MJ, Shah S, Peterson S, Baim S (2018) Rush Fracture Liaison Service for capturing “missed opportunities” to treat osteoporosis in patients with fragility fractures. Osteoporos Int 29:1861–1874PubMedCrossRef
17.
go back to reference Lewiecki EM, Rochelle R, Bouchonville MF 2nd, Chafey DH, Olenginski TP, Arora S (2017) Leveraging scarce resources with Bone Health TeleECHO to improve the care of osteoporosis. J Endocr Soc 1:1428–1434PubMedPubMedCentralCrossRef Lewiecki EM, Rochelle R, Bouchonville MF 2nd, Chafey DH, Olenginski TP, Arora S (2017) Leveraging scarce resources with Bone Health TeleECHO to improve the care of osteoporosis. J Endocr Soc 1:1428–1434PubMedPubMedCentralCrossRef
18.
go back to reference Feldstein A, Elmer PJ, Smith DH, Herson M, Orwoll E, Chen C, Aickin M, Swain MC (2006) Electronic medical record reminder improves osteoporosis management after a fracture: a randomized, controlled trial. J Am Geriatr Soc 54:450–457PubMedCrossRef Feldstein A, Elmer PJ, Smith DH, Herson M, Orwoll E, Chen C, Aickin M, Swain MC (2006) Electronic medical record reminder improves osteoporosis management after a fracture: a randomized, controlled trial. J Am Geriatr Soc 54:450–457PubMedCrossRef
19.
go back to reference Baim S (2017) The future of fracture risk assessment in the management of osteoporosis. J Clin Densitom 20:451–457PubMedCrossRef Baim S (2017) The future of fracture risk assessment in the management of osteoporosis. J Clin Densitom 20:451–457PubMedCrossRef
20.
go back to reference Rothman MS, Olenginski TP, Stanciu I, Krohn K, Lewiecki EM (2019) Lessons learned with Bone Health TeleECHO: making treatment decisions when guidelines conflict. Osteoporos Int 30:2401–2406PubMedCrossRef Rothman MS, Olenginski TP, Stanciu I, Krohn K, Lewiecki EM (2019) Lessons learned with Bone Health TeleECHO: making treatment decisions when guidelines conflict. Osteoporos Int 30:2401–2406PubMedCrossRef
21.
go back to reference Akesson K, Marsh D, Mitchell PJ, McLellan AR, Stenmark J, Pierroz DD, Kyer C, Cooper C, IOF Fracture Working Group (2013) Capture the fracture: a best practice framework and global campaign to break the fragility fracture cycle. Osteoporos Int 24:2135–2152PubMedPubMedCentralCrossRef Akesson K, Marsh D, Mitchell PJ, McLellan AR, Stenmark J, Pierroz DD, Kyer C, Cooper C, IOF Fracture Working Group (2013) Capture the fracture: a best practice framework and global campaign to break the fragility fracture cycle. Osteoporos Int 24:2135–2152PubMedPubMedCentralCrossRef
22.
go back to reference Clark EM, Gould V, Morrison L, Ades AE, Dieppe P, Tobias JH (2012) Randomized controlled trial of a primary care-based screening program to identify older women with prevalent osteoporotic vertebral fractures: cohort for Skeletal Health in Bristol and Avon (COSHIBA). J Bone Miner Res 27:664–671PubMedCrossRef Clark EM, Gould V, Morrison L, Ades AE, Dieppe P, Tobias JH (2012) Randomized controlled trial of a primary care-based screening program to identify older women with prevalent osteoporotic vertebral fractures: cohort for Skeletal Health in Bristol and Avon (COSHIBA). J Bone Miner Res 27:664–671PubMedCrossRef
23.
go back to reference Edwards BJ, Bunta AD, Anderson J, Bobb A, Hahr A, O'Leary KJ, Agulnek A, Andruszyn L, Cameron KA, May M, Kazmers NH, Dillon N, Baker DW, Williams MV (2012) Development of an electronic medical record based intervention to improve medical care of osteoporosis. Osteoporos Int 23:2489–2498PubMedCrossRef Edwards BJ, Bunta AD, Anderson J, Bobb A, Hahr A, O'Leary KJ, Agulnek A, Andruszyn L, Cameron KA, May M, Kazmers NH, Dillon N, Baker DW, Williams MV (2012) Development of an electronic medical record based intervention to improve medical care of osteoporosis. Osteoporos Int 23:2489–2498PubMedCrossRef
24.
go back to reference O'Brien LK, Armstrong AD, Hassenbein SE, Fox EJ (2015) Evaluation of patients' response toward osteoporosis letter intervention versus phone call plus letter intervention. Geriatr Orthop Surg Rehabil 6:246–250PubMedPubMedCentralCrossRef O'Brien LK, Armstrong AD, Hassenbein SE, Fox EJ (2015) Evaluation of patients' response toward osteoporosis letter intervention versus phone call plus letter intervention. Geriatr Orthop Surg Rehabil 6:246–250PubMedPubMedCentralCrossRef
25.
go back to reference Gosch M, Bail H-J, Grueninger S, Stumpf U, Kammerlander C, Wicklein S (2020) What is a reasonable rate for specific osteoporosis drug therapy in older fragility fracture patients? Arch Osteoporos 15:20PubMedCrossRef Gosch M, Bail H-J, Grueninger S, Stumpf U, Kammerlander C, Wicklein S (2020) What is a reasonable rate for specific osteoporosis drug therapy in older fragility fracture patients? Arch Osteoporos 15:20PubMedCrossRef
26.
go back to reference Beaupre LA, Moradi F, Khong H, Smith C, Evens L, Hanson HM, Juby AG, Kivi P, Majumdar SR, STOP-Fracture Team (2020) Implementation of an in-patient hip fracture liaison services to improve initiation of osteoporosis medication use within 1-year of hip fracture: a population-based time series analysis using the RE-AIM framework. Arch Osteoporos 15:83PubMedCrossRef Beaupre LA, Moradi F, Khong H, Smith C, Evens L, Hanson HM, Juby AG, Kivi P, Majumdar SR, STOP-Fracture Team (2020) Implementation of an in-patient hip fracture liaison services to improve initiation of osteoporosis medication use within 1-year of hip fracture: a population-based time series analysis using the RE-AIM framework. Arch Osteoporos 15:83PubMedCrossRef
27.
go back to reference Beaupre LA, Lier D, Smith C, Evens L, Hanson HM, Juby AG, Kivi P, Majumdar SR, STOP-Fracture Team (2020) A 3i hip fracture liaison service with nurse and physician co-management is cost-effective when implemented as a standard clinical program. Arch Osteoporos 15:113PubMedCrossRef Beaupre LA, Lier D, Smith C, Evens L, Hanson HM, Juby AG, Kivi P, Majumdar SR, STOP-Fracture Team (2020) A 3i hip fracture liaison service with nurse and physician co-management is cost-effective when implemented as a standard clinical program. Arch Osteoporos 15:113PubMedCrossRef
28.
go back to reference Kuiper BW, Graybill S, Tate JM, Kaufman N, Bersabe D (2018) After the fall: improving osteoporosis treatment following hip fracture. Osteoporos Int 29:1295–1301PubMedCrossRef Kuiper BW, Graybill S, Tate JM, Kaufman N, Bersabe D (2018) After the fall: improving osteoporosis treatment following hip fracture. Osteoporos Int 29:1295–1301PubMedCrossRef
29.
go back to reference Ruggiero C, Zampi E, Rinonapoli G, Baroni M, Serra R, Zengarini E, Baglioni G, Duranti G, Ercolani S, Conti F, Caraffa A, Mecocci P, Brandi ML (2015) Fracture prevention service to bridge the osteoporosis care gap. Clin Interv Aging 10:1035–1042PubMedPubMedCentral Ruggiero C, Zampi E, Rinonapoli G, Baroni M, Serra R, Zengarini E, Baglioni G, Duranti G, Ercolani S, Conti F, Caraffa A, Mecocci P, Brandi ML (2015) Fracture prevention service to bridge the osteoporosis care gap. Clin Interv Aging 10:1035–1042PubMedPubMedCentral
30.
go back to reference Abrahamsen C, Nørgaard B, Draborg E, Nielsen MF (2019) The impact of an orthogeriatric intervention in patients with fragility fractures: a cohort study. BMC Geriatr 19:268PubMedPubMedCentralCrossRef Abrahamsen C, Nørgaard B, Draborg E, Nielsen MF (2019) The impact of an orthogeriatric intervention in patients with fragility fractures: a cohort study. BMC Geriatr 19:268PubMedPubMedCentralCrossRef
31.
go back to reference Ong T, Sahota O, Gladman JRF (2020) The Nottingham Spinal Health (NoSH) Study: a cohort study of patients hospitalised with vertebral fragility fractures. Osteoporos Int 31:363–370PubMedCrossRef Ong T, Sahota O, Gladman JRF (2020) The Nottingham Spinal Health (NoSH) Study: a cohort study of patients hospitalised with vertebral fragility fractures. Osteoporos Int 31:363–370PubMedCrossRef
32.
go back to reference González-Quevedo D, Bautista-Enrique D, Pérez-del-Río V, Bravo-Bardají M, García-de-Quevedo D, Tamimi I (2020) Fracture liaison service and mortality in elderly hip fracture patients: a prospective cohort study. Osteoporos Int 31:77–84PubMedCrossRef González-Quevedo D, Bautista-Enrique D, Pérez-del-Río V, Bravo-Bardají M, García-de-Quevedo D, Tamimi I (2020) Fracture liaison service and mortality in elderly hip fracture patients: a prospective cohort study. Osteoporos Int 31:77–84PubMedCrossRef
33.
go back to reference Wozniak LA, Beaupre LA, Juby A, Kivi P, Majumdar SR, Hanson HM (2020) Successful implementation of a fracture liaison service through effective change management: a qualitative study. Arch Osteoporos 15:44PubMedPubMedCentralCrossRef Wozniak LA, Beaupre LA, Juby A, Kivi P, Majumdar SR, Hanson HM (2020) Successful implementation of a fracture liaison service through effective change management: a qualitative study. Arch Osteoporos 15:44PubMedPubMedCentralCrossRef
34.
go back to reference Naranjo A, Molina A, Sepúlveda C, Rubiño FJ, Martín N, Ojeda S (2020) The evolution of an FLS in search of excellence: the experience of Gran Canaria. Arch Osteoporos 15:108PubMedCrossRef Naranjo A, Molina A, Sepúlveda C, Rubiño FJ, Martín N, Ojeda S (2020) The evolution of an FLS in search of excellence: the experience of Gran Canaria. Arch Osteoporos 15:108PubMedCrossRef
35.
go back to reference Hoang-Kim A, Kanengisser D (2020) Developing registries and effective care models for the management of hip fractures: aligning political, organizational drivers with clinical outcomes. Curr Osteoporos Rep 18:180–188PubMedCrossRef Hoang-Kim A, Kanengisser D (2020) Developing registries and effective care models for the management of hip fractures: aligning political, organizational drivers with clinical outcomes. Curr Osteoporos Rep 18:180–188PubMedCrossRef
36.
go back to reference Majumdar SR, Lier DA, Hanley DA, Juby AG, Beaupre LA (2017) Economic evaluation of a population-based osteoporosis intervention for outpatients with non-traumatic non-hip fractures: the “Catch a Break” 1i [type C] FLS. Osteoporos Int 28:1965–1977PubMedPubMedCentralCrossRef Majumdar SR, Lier DA, Hanley DA, Juby AG, Beaupre LA (2017) Economic evaluation of a population-based osteoporosis intervention for outpatients with non-traumatic non-hip fractures: the “Catch a Break” 1i [type C] FLS. Osteoporos Int 28:1965–1977PubMedPubMedCentralCrossRef
37.
go back to reference Dirschl DR, Rustom H (2018) Practice patterns and performance in U.S. fracture liaison programs: an analysis of >32,000 patients from the Own the Bone program. J Bone Joint Surg Am 100:680–685PubMedCrossRef Dirschl DR, Rustom H (2018) Practice patterns and performance in U.S. fracture liaison programs: an analysis of >32,000 patients from the Own the Bone program. J Bone Joint Surg Am 100:680–685PubMedCrossRef
38.
go back to reference Stephens JR, Caraccio D, Mabry DR, Stepanek KV, Jones MS, Hemsey DF (1995) Moore CR (2021) Implementation of a fracture liaison service for patients with hip fracture cared for on a hospital medicine service. Hosp Pract 49:41–46CrossRef Stephens JR, Caraccio D, Mabry DR, Stepanek KV, Jones MS, Hemsey DF (1995) Moore CR (2021) Implementation of a fracture liaison service for patients with hip fracture cared for on a hospital medicine service. Hosp Pract 49:41–46CrossRef
39.
go back to reference Vranken L, Wyers CE, van Rietbergen B, Driessen JHM, Geusens PPMM, Janzing HMJ, van der Velde RY, van den Bergh JPW (2019) The association between prevalent vertebral fractures and bone quality of the distal radius and distal tibia as measured with HR-pQCT in postmenopausal women with a recent non-vertebral fracture at the Fracture Liaison Service. Osteoporos Int 30:1789–1797PubMedPubMedCentralCrossRef Vranken L, Wyers CE, van Rietbergen B, Driessen JHM, Geusens PPMM, Janzing HMJ, van der Velde RY, van den Bergh JPW (2019) The association between prevalent vertebral fractures and bone quality of the distal radius and distal tibia as measured with HR-pQCT in postmenopausal women with a recent non-vertebral fracture at the Fracture Liaison Service. Osteoporos Int 30:1789–1797PubMedPubMedCentralCrossRef
40.
go back to reference Ganda K, Puech M, Chen JS, Speerin R, Bleasel J, Center JR, Eisman JA, March L, Seibel MJ (2013) Models of care for the secondary prevention of osteoporotic fractures: a systematic review and meta-analysis. Osteoporos Int 24:393–406PubMedCrossRef Ganda K, Puech M, Chen JS, Speerin R, Bleasel J, Center JR, Eisman JA, March L, Seibel MJ (2013) Models of care for the secondary prevention of osteoporotic fractures: a systematic review and meta-analysis. Osteoporos Int 24:393–406PubMedCrossRef
41.
go back to reference Ganda K, Mitchell PJ, Seibel MJ (2019) Chapter 3 - models of secondary fracture prevention: systematic review and metaanalysis of outcomes. In: Seibel MJ, Mitchell PJ (eds) Secondary Fracture Prevention. Academic Press, London, pp 33–62CrossRef Ganda K, Mitchell PJ, Seibel MJ (2019) Chapter 3 - models of secondary fracture prevention: systematic review and metaanalysis of outcomes. In: Seibel MJ, Mitchell PJ (eds) Secondary Fracture Prevention. Academic Press, London, pp 33–62CrossRef
42.
go back to reference Senay A, Delisle J, Raynauld JP, Morin SN, Fernandes JC (2016) Agreement between physicians’ and nurses’ clinical decisions for the management of the fracture liaison service (4iFLS): the Lucky Bone™ program. Osteoporos Int 27:1569–1576PubMedCrossRef Senay A, Delisle J, Raynauld JP, Morin SN, Fernandes JC (2016) Agreement between physicians’ and nurses’ clinical decisions for the management of the fracture liaison service (4iFLS): the Lucky Bone™ program. Osteoporos Int 27:1569–1576PubMedCrossRef
43.
go back to reference Hung W-C, Yang C-H, Cheng W-L, Wu C-H (2019) Revisit three “I” model: a novel five “I” model of fracture liaison service. Osteoporos Int 30:2361–2362PubMedCrossRef Hung W-C, Yang C-H, Cheng W-L, Wu C-H (2019) Revisit three “I” model: a novel five “I” model of fracture liaison service. Osteoporos Int 30:2361–2362PubMedCrossRef
44.
go back to reference Palcu P, Munce S, Jaglal SB, Allin S, Chishtie JA, Silverstein A, Kim S (2020) Understanding patient experiences and challenges to osteoporosis care delivered virtually by telemedicine: a mixed methods study. Osteoporos Int 31:351–361PubMedCrossRef Palcu P, Munce S, Jaglal SB, Allin S, Chishtie JA, Silverstein A, Kim S (2020) Understanding patient experiences and challenges to osteoporosis care delivered virtually by telemedicine: a mixed methods study. Osteoporos Int 31:351–361PubMedCrossRef
45.
go back to reference Paskins Z, Crawford-Manning F, Bullock L, Jinks C (2020) Identifying and managing osteoporosis before and after COVID-19: rise of the remote consultation? Osteoporos Int 31:1629–1632PubMedPubMedCentralCrossRef Paskins Z, Crawford-Manning F, Bullock L, Jinks C (2020) Identifying and managing osteoporosis before and after COVID-19: rise of the remote consultation? Osteoporos Int 31:1629–1632PubMedPubMedCentralCrossRef
46.
go back to reference Marschollek M, Becker M, Bauer JM, Bente P, Dasenbrock L, Elbers K, Hein A, Kolb G, Künemund H, Lammel-Polchau C, Meis M, Zu M, Schwabedissen H, Remmers H, Schulze M, Steen EE, Thoben W, Wang J, Wolf KH, Haux R (2014) Multimodal activity monitoring for home rehabilitation of geriatric fracture patients—feasibility and acceptance of sensor systems in the GAL-NATARS study. Inform Health Soc Care 39:262–271PubMedCrossRef Marschollek M, Becker M, Bauer JM, Bente P, Dasenbrock L, Elbers K, Hein A, Kolb G, Künemund H, Lammel-Polchau C, Meis M, Zu M, Schwabedissen H, Remmers H, Schulze M, Steen EE, Thoben W, Wang J, Wolf KH, Haux R (2014) Multimodal activity monitoring for home rehabilitation of geriatric fracture patients—feasibility and acceptance of sensor systems in the GAL-NATARS study. Inform Health Soc Care 39:262–271PubMedCrossRef
47.
go back to reference Geerds MAJ, Nijmeijer WS, Hegeman JH, Vollenbroek-Hutten MMR (2020) Mobile app for monitoring 3-month postoperative functional outcome after hip fracture: usability study. JMIR Hum Factors 7:e16989PubMedPubMedCentralCrossRef Geerds MAJ, Nijmeijer WS, Hegeman JH, Vollenbroek-Hutten MMR (2020) Mobile app for monitoring 3-month postoperative functional outcome after hip fracture: usability study. JMIR Hum Factors 7:e16989PubMedPubMedCentralCrossRef
48.
go back to reference Martin J, Viprey M, Castagne B, Merle B, Giroudon C, Chapurlat R, Schott A-M (2020) Interventions to improve osteoporosis care: a systematic review and meta-analysis. Osteoporos Int 31:429–446PubMedCrossRef Martin J, Viprey M, Castagne B, Merle B, Giroudon C, Chapurlat R, Schott A-M (2020) Interventions to improve osteoporosis care: a systematic review and meta-analysis. Osteoporos Int 31:429–446PubMedCrossRef
49.
go back to reference Wu C-H, Tu S-T, Chang Y-F, Chan D-C, Chien J-T, Lin C-H, Singh S, Dasari M, Chen J-F, Tsai K-S (2018) Fracture liaison services improve outcomes of patients with osteoporosis-related fractures: a systematic literature review and meta-analysis. Bone 111:92–100PubMedCrossRef Wu C-H, Tu S-T, Chang Y-F, Chan D-C, Chien J-T, Lin C-H, Singh S, Dasari M, Chen J-F, Tsai K-S (2018) Fracture liaison services improve outcomes of patients with osteoporosis-related fractures: a systematic literature review and meta-analysis. Bone 111:92–100PubMedCrossRef
50.
go back to reference Senay A, Perreault S, Delisle J, Morin SN, Fernandes JC (2020) Performance of a fracture liaison service in an orthopaedic setting: a report of key indicators and improvement of longitudinal outcomes. J Bone Joint Surg Am 102:486–494PubMedCrossRef Senay A, Perreault S, Delisle J, Morin SN, Fernandes JC (2020) Performance of a fracture liaison service in an orthopaedic setting: a report of key indicators and improvement of longitudinal outcomes. J Bone Joint Surg Am 102:486–494PubMedCrossRef
51.
go back to reference French S, Choden S, Schmajuk G (2019) Quality measures and quality improvement initiatives in osteoporosis—an update. Curr Osteoporos Rep 17:491–509PubMedCrossRef French S, Choden S, Schmajuk G (2019) Quality measures and quality improvement initiatives in osteoporosis—an update. Curr Osteoporos Rep 17:491–509PubMedCrossRef
52.
go back to reference Javaid MK, Sami A, Lems W, Mitchell P, Thomas T, Singer A, Speerin R, Fujita M, Pierroz DD, Akesson K, Halbout P, Ferrari S, Cooper C (2020) A patient-level key performance indicator set to measure the effectiveness of fracture liaison services and guide quality improvement: a position paper of the IOF Capture the Fracture Working Group, National Osteoporosis Foundation and Fragility Fracture Network. Osteoporos Int 31:1193–1204PubMedPubMedCentralCrossRef Javaid MK, Sami A, Lems W, Mitchell P, Thomas T, Singer A, Speerin R, Fujita M, Pierroz DD, Akesson K, Halbout P, Ferrari S, Cooper C (2020) A patient-level key performance indicator set to measure the effectiveness of fracture liaison services and guide quality improvement: a position paper of the IOF Capture the Fracture Working Group, National Osteoporosis Foundation and Fragility Fracture Network. Osteoporos Int 31:1193–1204PubMedPubMedCentralCrossRef
53.
go back to reference Sale JEM, Beaton D, Posen J, Elliot-Gibson V, Bogoch E (2014) Key outcomes are usually not reported in published fracture secondary prevention programs: results of a systematic review. Arch Orthop Trauma Surg 134:283–289PubMedCrossRef Sale JEM, Beaton D, Posen J, Elliot-Gibson V, Bogoch E (2014) Key outcomes are usually not reported in published fracture secondary prevention programs: results of a systematic review. Arch Orthop Trauma Surg 134:283–289PubMedCrossRef
54.
go back to reference Voeten SC, Arends AJ, Wouters MWJM, Blom BJ, Heetveld MJ, Slee-Valentijn MS, Krijnen P, Schipper IB, JHH H, Dutch Hip Fracture Audit Group (2019) The Dutch Hip Fracture Audit: evaluation of the quality of multidisciplinary hip fracture care in the Netherlands. Arch Osteoporos 14:28PubMedPubMedCentralCrossRef Voeten SC, Arends AJ, Wouters MWJM, Blom BJ, Heetveld MJ, Slee-Valentijn MS, Krijnen P, Schipper IB, JHH H, Dutch Hip Fracture Audit Group (2019) The Dutch Hip Fracture Audit: evaluation of the quality of multidisciplinary hip fracture care in the Netherlands. Arch Osteoporos 14:28PubMedPubMedCentralCrossRef
55.
go back to reference Liem IS, Kammerlander C, Suhm N, Blauth M, Roth T, Gosch M, Hoang-Kim A, Mendelson D, Zuckerman J, Leung F, Burton J, Moran C, Parker M, Giusti A, Pioli G, Goldhahn J, Kates SL (2013) Identifying a standard set of outcome parameters for the evaluation of orthogeriatric co-management for hip fractures. Injury 44:1403–1412PubMedCrossRef Liem IS, Kammerlander C, Suhm N, Blauth M, Roth T, Gosch M, Hoang-Kim A, Mendelson D, Zuckerman J, Leung F, Burton J, Moran C, Parker M, Giusti A, Pioli G, Goldhahn J, Kates SL (2013) Identifying a standard set of outcome parameters for the evaluation of orthogeriatric co-management for hip fractures. Injury 44:1403–1412PubMedCrossRef
60.
go back to reference Aboudiab M, Grados F, Batteux B, Henry-Desailly I, Fardellone P, Goëb V (2020) Vertebral fracture assessment (VFA) in patients over 50 years of age with a non-severe peripheral fracture. Osteoporos Int 31:1477–1486PubMedCrossRef Aboudiab M, Grados F, Batteux B, Henry-Desailly I, Fardellone P, Goëb V (2020) Vertebral fracture assessment (VFA) in patients over 50 years of age with a non-severe peripheral fracture. Osteoporos Int 31:1477–1486PubMedCrossRef
61.
go back to reference Schousboe JT, Lix LM, Morin SN, Derkatch S, Bryanton M, Alhrbi M, Leslie WD (2019) Vertebral fracture assessment increases use of pharmacologic therapy for fracture prevention in clinical practice. J Bone Miner Res 34:2205–2212PubMedCrossRef Schousboe JT, Lix LM, Morin SN, Derkatch S, Bryanton M, Alhrbi M, Leslie WD (2019) Vertebral fracture assessment increases use of pharmacologic therapy for fracture prevention in clinical practice. J Bone Miner Res 34:2205–2212PubMedCrossRef
62.
go back to reference Schousboe JT, Lix LM, Morin SN, Derkatch S, Bryanton M, Alhrbi M, Leslie WD (2019) Prevalent vertebral fracture on bone density lateral spine (VFA) images in routine clinical practice predict incident fractures. Bone 121:72–79PubMedCrossRef Schousboe JT, Lix LM, Morin SN, Derkatch S, Bryanton M, Alhrbi M, Leslie WD (2019) Prevalent vertebral fracture on bone density lateral spine (VFA) images in routine clinical practice predict incident fractures. Bone 121:72–79PubMedCrossRef
63.
go back to reference Cosman F, de Beur SJ, LeBoff MS, Lewiecki EM, Tanner B, Randall S, Lindsay R (2014) Clinician’s guide to prevention and treatment of osteoporosis. Osteoporos Int 25:2359–2381PubMedPubMedCentralCrossRef Cosman F, de Beur SJ, LeBoff MS, Lewiecki EM, Tanner B, Randall S, Lindsay R (2014) Clinician’s guide to prevention and treatment of osteoporosis. Osteoporos Int 25:2359–2381PubMedPubMedCentralCrossRef
64.
go back to reference Rosen HN, Vokes TJ, Malabanan AO, Deal CL, Alele JD, Olenginski TP, Schousboe JT (2013) The official positions of the International Society for Clinical Densitometry: vertebral fracture assessment. J Clin Densitom 16:482–488PubMedCrossRef Rosen HN, Vokes TJ, Malabanan AO, Deal CL, Alele JD, Olenginski TP, Schousboe JT (2013) The official positions of the International Society for Clinical Densitometry: vertebral fracture assessment. J Clin Densitom 16:482–488PubMedCrossRef
65.
go back to reference Hawley S, Javaid MK, Prieto-Alhambra D, Lippett J, Sheard S, Arden NK, Cooper C, Judge A, REFReSH Study Group (2016) Clinical effectiveness of orthogeriatric and fracture liaison service models of care for hip fracture patients: population-based longitudinal study. Age Ageing 45:236–242PubMedPubMedCentralCrossRef Hawley S, Javaid MK, Prieto-Alhambra D, Lippett J, Sheard S, Arden NK, Cooper C, Judge A, REFReSH Study Group (2016) Clinical effectiveness of orthogeriatric and fracture liaison service models of care for hip fracture patients: population-based longitudinal study. Age Ageing 45:236–242PubMedPubMedCentralCrossRef
66.
go back to reference Neuerburg C, Mittlmeier L, Schmidmaier R, Kammerlander C, Böcker W, Mutschler W, Stumpf U (2017) Investigation and management of osteoporosis in aged trauma patients: a treatment algorithm adapted to the German guidelines for osteoporosis. J Orthop Surg Res 12:86PubMedPubMedCentralCrossRef Neuerburg C, Mittlmeier L, Schmidmaier R, Kammerlander C, Böcker W, Mutschler W, Stumpf U (2017) Investigation and management of osteoporosis in aged trauma patients: a treatment algorithm adapted to the German guidelines for osteoporosis. J Orthop Surg Res 12:86PubMedPubMedCentralCrossRef
67.
go back to reference Li H, Wang Y, Wang R, Yue L, Chen S, Li C (2020) Effects of rosuvastatin and zoledronic acid in combination on the recovery of senile osteoporotic vertebral compression fracture following percutaneous vertebroplasty. J Int Med Res 48:300060520925390PubMed Li H, Wang Y, Wang R, Yue L, Chen S, Li C (2020) Effects of rosuvastatin and zoledronic acid in combination on the recovery of senile osteoporotic vertebral compression fracture following percutaneous vertebroplasty. J Int Med Res 48:300060520925390PubMed
68.
go back to reference Liu Z, Li C-W, Mao Y-F, Liu K, Liang B-C, Wu L-G, Shi X-L (2019) Study on zoledronic acid reducing acute bone loss and fracture rates in elderly postoperative patients with intertrochanteric fractures. Orthop Surg 11:380–385PubMedPubMedCentralCrossRef Liu Z, Li C-W, Mao Y-F, Liu K, Liang B-C, Wu L-G, Shi X-L (2019) Study on zoledronic acid reducing acute bone loss and fracture rates in elderly postoperative patients with intertrochanteric fractures. Orthop Surg 11:380–385PubMedPubMedCentralCrossRef
69.
go back to reference Jia KQ, Southerland L, Phieffer L, Stephens JA, Ing SW (2020) Incorporation of a patient navigator into a secondary fracture prevention program identifies barriers to patient care. Aging Clin Exp Res 32:2557–2564PubMedCrossRef Jia KQ, Southerland L, Phieffer L, Stephens JA, Ing SW (2020) Incorporation of a patient navigator into a secondary fracture prevention program identifies barriers to patient care. Aging Clin Exp Res 32:2557–2564PubMedCrossRef
70.
go back to reference Martin J, Viprey M, Castagne B, Barral M, Chapurlat R, Julien C, Serrier H, Schott A-M (2020) Cost-effectiveness analyses of interventions to improve osteoporosis care in France. Arch Osteoporos 15:42PubMedCrossRef Martin J, Viprey M, Castagne B, Barral M, Chapurlat R, Julien C, Serrier H, Schott A-M (2020) Cost-effectiveness analyses of interventions to improve osteoporosis care in France. Arch Osteoporos 15:42PubMedCrossRef
71.
go back to reference Majumdar SR, Lier DA, McAlister FA, Johnson JA, Rowe BH, Beaupre LA (2019) Cost-effectiveness of osteoporosis interventions to improve quality of care after upper extremity fracture: results from a randomized trial (C-STOP Trial). J Bone Miner Res 34:1220–1228PubMedCrossRef Majumdar SR, Lier DA, McAlister FA, Johnson JA, Rowe BH, Beaupre LA (2019) Cost-effectiveness of osteoporosis interventions to improve quality of care after upper extremity fracture: results from a randomized trial (C-STOP Trial). J Bone Miner Res 34:1220–1228PubMedCrossRef
72.
go back to reference Clement RC, Ahn J, Mehta S, Bernstein J (2013) Economic viability of geriatric hip fracture centers. Orthopedics 36:e1509–e1514PubMedCrossRef Clement RC, Ahn J, Mehta S, Bernstein J (2013) Economic viability of geriatric hip fracture centers. Orthopedics 36:e1509–e1514PubMedCrossRef
73.
go back to reference Metcalfe D, Zogg CK, Judge A, Perry DC, Gabbe B, Willett K, Costa ML (2019) Pay for performance and hip fracture outcomes: an interrupted time series and difference-in-differences analysis in England and Scotland. Bone Joint J 101-B:1015–1023PubMedPubMedCentralCrossRef Metcalfe D, Zogg CK, Judge A, Perry DC, Gabbe B, Willett K, Costa ML (2019) Pay for performance and hip fracture outcomes: an interrupted time series and difference-in-differences analysis in England and Scotland. Bone Joint J 101-B:1015–1023PubMedPubMedCentralCrossRef
74.
go back to reference Nishi T, Maeda T, Babazono A (2018) Association between financial incentives for regional care coordination and health care resource utilization among older patients after femoral neck fracture surgery: a retrospective cohort study using a claims database. Popul Health Manag 21:331–337PubMedCrossRef Nishi T, Maeda T, Babazono A (2018) Association between financial incentives for regional care coordination and health care resource utilization among older patients after femoral neck fracture surgery: a retrospective cohort study using a claims database. Popul Health Manag 21:331–337PubMedCrossRef
75.
go back to reference Valentin G, Pedersen SE, Christensen R, Friis K, Nielsen CP, Bhimjiyani A, Gregson CL, Langdahl BL (2020) Socio-economic inequalities in fragility fracture outcomes: a systematic review and meta-analysis of prognostic observational studies. Osteoporos Int 31:31–42PubMedCrossRef Valentin G, Pedersen SE, Christensen R, Friis K, Nielsen CP, Bhimjiyani A, Gregson CL, Langdahl BL (2020) Socio-economic inequalities in fragility fracture outcomes: a systematic review and meta-analysis of prognostic observational studies. Osteoporos Int 31:31–42PubMedCrossRef
76.
go back to reference Malik AT, Retchin S, Phillips FM, Xu W, Peters K, Yu E, Khan SN (2020) Declining trend in osteoporosis management and screening following vertebral compression fractures – a national analysis of commercial insurance and medicare advantage beneficiaries. Spine J 20:538–546 Malik AT, Retchin S, Phillips FM, Xu W, Peters K, Yu E, Khan SN (2020) Declining trend in osteoporosis management and screening following vertebral compression fractures – a national analysis of commercial insurance and medicare advantage beneficiaries. Spine J 20:538–546
77.
go back to reference Ong T, Copeland R, Thiam CN, Cerda Mas G, Marshall L, Sahota O (2021) Integration of a vertebral fracture identification service into a fracture liaison service: a quality improvement project. Osteoporos Int 32:921–926PubMedCrossRef Ong T, Copeland R, Thiam CN, Cerda Mas G, Marshall L, Sahota O (2021) Integration of a vertebral fracture identification service into a fracture liaison service: a quality improvement project. Osteoporos Int 32:921–926PubMedCrossRef
78.
go back to reference Howlett DC, Drinkwater KJ, Mahmood N, Illes J, Griffin J, Javaid K (2020) Radiology reporting of osteoporotic vertebral fragility fractures on computed tomography studies: results of a UK national audit. Eur Radiol 30:4713–4723PubMedCrossRef Howlett DC, Drinkwater KJ, Mahmood N, Illes J, Griffin J, Javaid K (2020) Radiology reporting of osteoporotic vertebral fragility fractures on computed tomography studies: results of a UK national audit. Eur Radiol 30:4713–4723PubMedCrossRef
79.
go back to reference Toal M, McLoughlin C, Pierce N, Moss J, English S, Lindsay JR (2020) Detection of vertebral fracture in an acute hospital setting: an intervention to reduce future fracture risk through fracture liaison service intervention? Arch Osteoporos 15:160PubMedPubMedCentralCrossRef Toal M, McLoughlin C, Pierce N, Moss J, English S, Lindsay JR (2020) Detection of vertebral fracture in an acute hospital setting: an intervention to reduce future fracture risk through fracture liaison service intervention? Arch Osteoporos 15:160PubMedPubMedCentralCrossRef
80.
go back to reference Schousboe JT, Davison ML, Dowd B, Thiede Call K, Johnson P, Kane RL (2011) Predictors of patients’ perceived need for medication to prevent fracture. Med Care 49:273–280PubMedCrossRef Schousboe JT, Davison ML, Dowd B, Thiede Call K, Johnson P, Kane RL (2011) Predictors of patients’ perceived need for medication to prevent fracture. Med Care 49:273–280PubMedCrossRef
81.
go back to reference Abbad N, Lemeunier L, Chantelot C, Puisieux F, Cortet B (2016) Secondary prevention program for osteoporotic fractures at Lille University Hospital. Presse Med 45:375–377PubMedCrossRef Abbad N, Lemeunier L, Chantelot C, Puisieux F, Cortet B (2016) Secondary prevention program for osteoporotic fractures at Lille University Hospital. Presse Med 45:375–377PubMedCrossRef
82.
go back to reference Bunta AD, Edwards BJ, Macaulay WB Jr, Jeray KJ, Tosi LL, Jones CB, Sietsema DL, Kaufman JD, Murphy SA, Song J, Goulet JA, Friedlaender GE, Swiontkowski MF, Dirschl DR (2016) Own the bone, a system-based intervention, improves osteoporosis care after fragility fractures. J Bone Joint Surg Am 98:e109PubMedPubMedCentralCrossRef Bunta AD, Edwards BJ, Macaulay WB Jr, Jeray KJ, Tosi LL, Jones CB, Sietsema DL, Kaufman JD, Murphy SA, Song J, Goulet JA, Friedlaender GE, Swiontkowski MF, Dirschl DR (2016) Own the bone, a system-based intervention, improves osteoporosis care after fragility fractures. J Bone Joint Surg Am 98:e109PubMedPubMedCentralCrossRef
84.
go back to reference Kanis JA, Cooper C, Rizzoli R, Reginster J-Y (2019) European guidance for the diagnosis and management of osteoporosis in postmenopausal women. Osteoporos Int 30:3–44PubMedCrossRef Kanis JA, Cooper C, Rizzoli R, Reginster J-Y (2019) European guidance for the diagnosis and management of osteoporosis in postmenopausal women. Osteoporos Int 30:3–44PubMedCrossRef
85.
go back to reference Camacho PM, Petak SM, Binkley N, Diab DL, Eldeiry LS, Farooki A, Harris ST, Hurley DL, Kelly J, Lewiecki EM, Pessah-Pollack R, McClung M, Wimalawansa SJ, Watts NB (2020) American Association of Clinical Endocrinologists/American College of Endocrinology clinical practice guidelines for the diagnosis and treatment of postmenopausal osteoporosis—2020 update. Endocr Pract 26:1–46PubMedCrossRef Camacho PM, Petak SM, Binkley N, Diab DL, Eldeiry LS, Farooki A, Harris ST, Hurley DL, Kelly J, Lewiecki EM, Pessah-Pollack R, McClung M, Wimalawansa SJ, Watts NB (2020) American Association of Clinical Endocrinologists/American College of Endocrinology clinical practice guidelines for the diagnosis and treatment of postmenopausal osteoporosis—2020 update. Endocr Pract 26:1–46PubMedCrossRef
86.
go back to reference Eastell R, Rosen CJ, Black DM, Cheung AM, Murad MH, Shoback D (2019) Pharmacological management of osteoporosis in postmenopausal women: an Endocrine Society* clinical practice guideline. J Clin Endocrinol Metab 104:1595–1622PubMedCrossRef Eastell R, Rosen CJ, Black DM, Cheung AM, Murad MH, Shoback D (2019) Pharmacological management of osteoporosis in postmenopausal women: an Endocrine Society* clinical practice guideline. J Clin Endocrinol Metab 104:1595–1622PubMedCrossRef
87.
go back to reference Kanis JA, Harvey NC, McCloskey E, Bruyère O, Veronese N, Lorentzon M, Cooper C, Rizzoli R, Adib G, Al-Daghri N, Campusano C, Chandran M, Dawson-Hughes B, Javaid K, Jiwa F, Johansson H, Lee JK, Liu E, Messina D et al (2020) Algorithm for the management of patients at low, high and very high risk of osteoporotic fractures. Osteoporos Int 31:1–12PubMedCrossRef Kanis JA, Harvey NC, McCloskey E, Bruyère O, Veronese N, Lorentzon M, Cooper C, Rizzoli R, Adib G, Al-Daghri N, Campusano C, Chandran M, Dawson-Hughes B, Javaid K, Jiwa F, Johansson H, Lee JK, Liu E, Messina D et al (2020) Algorithm for the management of patients at low, high and very high risk of osteoporotic fractures. Osteoporos Int 31:1–12PubMedCrossRef
88.
go back to reference Chui K, Thakrar A, Shankar S (2020) Evaluating the efficacy of a two-site (‘COVID-19’ and ‘COVID-19-free’) trauma and orthopaedic service for the management of hip fractures during the COVID-19 pandemic in the UK. Bone Jt Open 1:190–197PubMedPubMedCentralCrossRef Chui K, Thakrar A, Shankar S (2020) Evaluating the efficacy of a two-site (‘COVID-19’ and ‘COVID-19-free’) trauma and orthopaedic service for the management of hip fractures during the COVID-19 pandemic in the UK. Bone Jt Open 1:190–197PubMedPubMedCentralCrossRef
Metadata
Title
Post-fracture care programs for prevention of subsequent fragility fractures: a literature assessment of current trends
Authors
K.E. Åkesson
K. Ganda
C. Deignan
M.K. Oates
A. Volpert
K. Brooks
D. Lee
D.R. Dirschl
A.J. Singer
Publication date
24-03-2022
Publisher
Springer London
Published in
Osteoporosis International / Issue 8/2022
Print ISSN: 0937-941X
Electronic ISSN: 1433-2965
DOI
https://doi.org/10.1007/s00198-022-06358-2

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