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Published in: Osteoporosis International 7/2020

Open Access 01-07-2020 | Osteoporosis | Position Paper

A patient-level key performance indicator set to measure the effectiveness of fracture liaison services and guide quality improvement: a position paper of the IOF Capture the Fracture Working Group, National Osteoporosis Foundation and Fragility Fracture Network

Authors: M. K. Javaid, A. Sami, W. Lems, P. Mitchell, T. Thomas, A. Singer, R. Speerin, M. Fujita, D. D. Pierroz, K. Akesson, P. Halbout, S. Ferrari, C. Cooper

Published in: Osteoporosis International | Issue 7/2020

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Abstract

Summary

The International Osteoporosis Foundation (IOF) Capture the Fracture® Campaign with the Fragility Fracture Network (FFN) and National Osteoporosis Foundation (NOF) has developed eleven patient-level key performance indicators (KPIs) for fracture liaison services (FLSs) to guide quality improvement.

Introduction

Fracture Liaison Services (FLSs) are recommended worldwide to reduce fracture risk after a sentinel fracture. Given not every FLS is automatically effective, the IOF Capture the Fracture working group has developed and implemented the Best Practice Framework to assess the organisational components of an FLS. We have now developed a complimentary KPI set that extends this assessment of performance to the patient level.

Methods

The Capture the Fracture working group in collaboration with the Fragility Fracture Network Secondary Fragility Fracture Special Interest Group and National Osteoporosis Foundation adapted existing metrics from the UK-based Fracture Liaison Service Database Audit to develop a patient-level KPI set for FLSs.

Results

Eleven KPIs were selected. The proportion of patients: with non-spinal fractures; with spine fractures (detected clinically and radiologically); assessed for fracture risk within 12 weeks of sentinel fracture; having DXA assessment within 12 weeks of sentinel fracture; having falls risk assessment; recommended anti-osteoporosis medication; commenced of strength and balance exercise intervention within 16 weeks of sentinel fracture; monitored within 16 weeks of sentinel fracture; started anti-osteoporosis medication within 16 weeks of sentinel fracture; prescribed anti-osteoporosis medication 52 weeks after sentinel fracture. The final KPI measures data completeness for each of the other KPIs. For these indicators, levels of achievement were set at the < 50%, 50–80% and > 80% levels except for treatment recommendation where a level of 50% was used.

Conclusion

This KPI set compliments the existing Best Practice Framework to support FLSs to examine their own performance using patient-level data. By using this KPI set for local quality improvement cycles, FLSs will be able to efficiently realise the full potential of secondary fracture prevention and improved clinical outcomes for their local populations.
Literature
1.
go back to reference Briggs AM et al (2019) Integrated prevention and management of non-communicable diseases, including musculoskeletal health: a systematic policy analysis among OECD countries. BMJ Glob Health 4(5):e001806PubMedPubMedCentralCrossRef Briggs AM et al (2019) Integrated prevention and management of non-communicable diseases, including musculoskeletal health: a systematic policy analysis among OECD countries. BMJ Glob Health 4(5):e001806PubMedPubMedCentralCrossRef
2.
go back to reference (2018) Global, regional, and national incidence, prevalence, and years lived with disability for 354 diseases and injuries for 195 countries and territories, 1990-2017: a systematic analysis for the Global Burden of Disease Study 2017. Lancet 392(10159):1789–1858 (2018) Global, regional, and national incidence, prevalence, and years lived with disability for 354 diseases and injuries for 195 countries and territories, 1990-2017: a systematic analysis for the Global Burden of Disease Study 2017. Lancet 392(10159):1789–1858
4.
go back to reference Marsh D et al (2011) Coordinator-based systems for secondary prevention in fragility fracture patients. Osteoporos Int 22(7):2051–2065PubMedCrossRef Marsh D et al (2011) Coordinator-based systems for secondary prevention in fragility fracture patients. Osteoporos Int 22(7):2051–2065PubMedCrossRef
5.
go back to reference Eisman JA et al (2012) Making the first fracture the last fracture: ASBMR task force report on secondary fracture prevention. J Bone Miner Res Eisman JA et al (2012) Making the first fracture the last fracture: ASBMR task force report on secondary fracture prevention. J Bone Miner Res
6.
go back to reference Kanis JA, Cooper C, Rizzoli R, Reginster JY, Scientific Advisory Board of the European Society for Clinical and Economic Aspects of Osteoporosis (ESCEO) and the Committees of Scientific Advisors and National Societies of the International Osteoporosis Foundation (IOF) (2019) European guidance for the diagnosis and management of osteoporosis in postmenopausal women. Osteoporos Int 30(1):3–44PubMedCrossRef Kanis JA, Cooper C, Rizzoli R, Reginster JY, Scientific Advisory Board of the European Society for Clinical and Economic Aspects of Osteoporosis (ESCEO) and the Committees of Scientific Advisors and National Societies of the International Osteoporosis Foundation (IOF) (2019) European guidance for the diagnosis and management of osteoporosis in postmenopausal women. Osteoporos Int 30(1):3–44PubMedCrossRef
7.
go back to reference Blain H et al (2016) A comprehensive fracture prevention strategy in older adults: the European Union Geriatric Medicine Society (EUGMS) statement. Aging Clin Exp Res 28(4):797–803PubMedCrossRef Blain H et al (2016) A comprehensive fracture prevention strategy in older adults: the European Union Geriatric Medicine Society (EUGMS) statement. Aging Clin Exp Res 28(4):797–803PubMedCrossRef
8.
go back to reference Lems WF, Dreinhöfer KE, Bischoff-Ferrari H, Blauth M, Czerwinski E, da Silva J, Herrera A, Hoffmeyer P, Kvien T, Maalouf G, Marsh D, Puget J, Puhl W, Poor G, Rasch L, Roux C, Schüler S, Seriolo B, Tarantino U, van Geel T, Woolf A, Wyers C, Geusens P (2017) EULAR/EFORT recommendations for management of patients older than 50 years with a fragility fracture and prevention of subsequent fractures. Ann Rheum Dis 76(5):802–810PubMedCrossRef Lems WF, Dreinhöfer KE, Bischoff-Ferrari H, Blauth M, Czerwinski E, da Silva J, Herrera A, Hoffmeyer P, Kvien T, Maalouf G, Marsh D, Puget J, Puhl W, Poor G, Rasch L, Roux C, Schüler S, Seriolo B, Tarantino U, van Geel T, Woolf A, Wyers C, Geusens P (2017) EULAR/EFORT recommendations for management of patients older than 50 years with a fragility fracture and prevention of subsequent fractures. Ann Rheum Dis 76(5):802–810PubMedCrossRef
10.
go back to reference Kim SC, Kim DH, Mogun H, Eddings W, Polinski JM, Franklin JM, Solomon DH (2016) Impact of the U.S. Food and Drug Administration’s safety-related announcements on the use of bisphosphonates after hip fracture. J Bone Miner Res 31(8):1536–1540PubMedPubMedCentralCrossRef Kim SC, Kim DH, Mogun H, Eddings W, Polinski JM, Franklin JM, Solomon DH (2016) Impact of the U.S. Food and Drug Administration’s safety-related announcements on the use of bisphosphonates after hip fracture. J Bone Miner Res 31(8):1536–1540PubMedPubMedCentralCrossRef
11.
go back to reference Michael Lewiecki E et al (2018) Hip fracture trends in the United States, 2002 to 2015. Osteoporos Int 29(3):717–722PubMedCrossRef Michael Lewiecki E et al (2018) Hip fracture trends in the United States, 2002 to 2015. Osteoporos Int 29(3):717–722PubMedCrossRef
12.
go back to reference McLellan AR et al (2003) The fracture liaison service: success of a program for the evaluation and management of patients with osteoporotic fracture. Osteoporos Int 14(12):1028–1034PubMedCrossRef McLellan AR et al (2003) The fracture liaison service: success of a program for the evaluation and management of patients with osteoporotic fracture. Osteoporos Int 14(12):1028–1034PubMedCrossRef
13.
go back to reference Ganda K, Puech M, Chen JS, Speerin R, Bleasel J, Center JR, Eisman JA, March L, Seibel MJ (2013) Models of care for the secondary prevention of osteoporotic fractures: a systematic review and meta-analysis. Osteoporos Int 24(2):393–406PubMedCrossRef Ganda K, Puech M, Chen JS, Speerin R, Bleasel J, Center JR, Eisman JA, March L, Seibel MJ (2013) Models of care for the secondary prevention of osteoporotic fractures: a systematic review and meta-analysis. Osteoporos Int 24(2):393–406PubMedCrossRef
14.
go back to reference Wu CH, Chen CH, Chen PH, Yang JJ, Chang PC, Huang TC, Bagga S, Sharma Y, Lin RM, Chan DC (2018) Identifying characteristics of an effective fracture liaison service: systematic literature review. Osteoporos Int 29(5):1023–1047PubMedCrossRef Wu CH, Chen CH, Chen PH, Yang JJ, Chang PC, Huang TC, Bagga S, Sharma Y, Lin RM, Chan DC (2018) Identifying characteristics of an effective fracture liaison service: systematic literature review. Osteoporos Int 29(5):1023–1047PubMedCrossRef
15.
go back to reference Wu CH, Kao IJ, Hung WC, Lin SC, Liu HC, Hsieh MH, Bagga S, Achra M, Cheng TT, Yang RS (2018) Economic impact and cost-effectiveness of fracture liaison services: a systematic review of the literature. Osteoporos Int 29(6):1227–1242PubMedCrossRef Wu CH, Kao IJ, Hung WC, Lin SC, Liu HC, Hsieh MH, Bagga S, Achra M, Cheng TT, Yang RS (2018) Economic impact and cost-effectiveness of fracture liaison services: a systematic review of the literature. Osteoporos Int 29(6):1227–1242PubMedCrossRef
17.
go back to reference Akesson K, Marsh D, Mitchell PJ, McLellan A, Stenmark J, Pierroz DD, Kyer C, Cooper C, IOF Fracture Working Group (2013) Capture the Fracture: a Best Practice Framework and global campaign to break the fragility fracture cycle. Osteoporos Int 24(8):2135–2152PubMedPubMedCentralCrossRef Akesson K, Marsh D, Mitchell PJ, McLellan A, Stenmark J, Pierroz DD, Kyer C, Cooper C, IOF Fracture Working Group (2013) Capture the Fracture: a Best Practice Framework and global campaign to break the fragility fracture cycle. Osteoporos Int 24(8):2135–2152PubMedPubMedCentralCrossRef
18.
go back to reference Javaid MK et al (2015) Effective secondary fracture prevention: implementation of a global benchmarking of clinical quality using the IOF Capture the Fracture(R) Best Practice Framework tool. Osteoporos Int 26(11):2573–2578PubMedCrossRef Javaid MK et al (2015) Effective secondary fracture prevention: implementation of a global benchmarking of clinical quality using the IOF Capture the Fracture(R) Best Practice Framework tool. Osteoporos Int 26(11):2573–2578PubMedCrossRef
19.
go back to reference Javaid MK et al (2017) Fracture Liaison Service Database (FLS-DB) annual report: leading FLS improvement: secondary fracture prevention in the NHS, F.a.F.F.A. Programme, Editor. Healthcare Quality Improvement Partnership, London Javaid MK et al (2017) Fracture Liaison Service Database (FLS-DB) annual report: leading FLS improvement: secondary fracture prevention in the NHS, F.a.F.F.A. Programme, Editor. Healthcare Quality Improvement Partnership, London
20.
go back to reference Javaid MK et al (2018) Fracture Liaison Service Database annual report December 2018: achieving effective service delivery by Fracture Liaison Services. Royal College of Physicians, London Javaid MK et al (2018) Fracture Liaison Service Database annual report December 2018: achieving effective service delivery by Fracture Liaison Services. Royal College of Physicians, London
21.
go back to reference Marsh D et al (2015) Secondary fracture prevention: first steps to a national audit, R.C.o. Physicians, Editor Marsh D et al (2015) Secondary fracture prevention: first steps to a national audit, R.C.o. Physicians, Editor
22.
go back to reference Ballane G, Cauley JA, Luckey MM, el-Hajj Fuleihan G (2017) Worldwide prevalence and incidence of osteoporotic vertebral fractures. Osteoporos Int 28(5):1531–1542PubMedCrossRef Ballane G, Cauley JA, Luckey MM, el-Hajj Fuleihan G (2017) Worldwide prevalence and incidence of osteoporotic vertebral fractures. Osteoporos Int 28(5):1531–1542PubMedCrossRef
23.
go back to reference Kanis JA, Johansson H, Odén A, Harvey NC, Gudnason V, Sanders KM, Sigurdsson G, Siggeirsdottir K, Fitzpatrick LA, Borgström F, McCloskey E (2018) Characteristics of recurrent fractures. Osteoporos Int 29(8):1747–1757PubMedPubMedCentralCrossRef Kanis JA, Johansson H, Odén A, Harvey NC, Gudnason V, Sanders KM, Sigurdsson G, Siggeirsdottir K, Fitzpatrick LA, Borgström F, McCloskey E (2018) Characteristics of recurrent fractures. Osteoporos Int 29(8):1747–1757PubMedPubMedCentralCrossRef
24.
go back to reference Barton DW, Behrend CJ, Carmouche JJ (2018) Rates of osteoporosis screening and treatment following vertebral fracture. Spine J Barton DW, Behrend CJ, Carmouche JJ (2018) Rates of osteoporosis screening and treatment following vertebral fracture. Spine J
25.
go back to reference van der Velde RY et al (2017) Effect of implementation of guidelines on assessment and diagnosis of vertebral fractures in patients older than 50 years with a recent non-vertebral fracture. Osteoporos Int 28(10):3017–3022PubMedPubMedCentralCrossRef van der Velde RY et al (2017) Effect of implementation of guidelines on assessment and diagnosis of vertebral fractures in patients older than 50 years with a recent non-vertebral fracture. Osteoporos Int 28(10):3017–3022PubMedPubMedCentralCrossRef
26.
go back to reference Gallacher SJ et al (2007) The prevalence of vertebral fracture amongst patients presenting with non-vertebral fractures. Osteoporos Int 18(2):185–192PubMedCrossRef Gallacher SJ et al (2007) The prevalence of vertebral fracture amongst patients presenting with non-vertebral fractures. Osteoporos Int 18(2):185–192PubMedCrossRef
27.
go back to reference Pandya J, Ganda K, Ridley L, Seibel MJ (2019) Identification of patients with osteoporotic vertebral fractures via simple text search of routine radiology reports. Calcif Tissue Int 105(2):156–160PubMedCrossRef Pandya J, Ganda K, Ridley L, Seibel MJ (2019) Identification of patients with osteoporotic vertebral fractures via simple text search of routine radiology reports. Calcif Tissue Int 105(2):156–160PubMedCrossRef
28.
go back to reference Lentle B et al (2019) The radiology of osteoporotic vertebral fractures revisited. J Bone Miner Res 34(3):409–418PubMedCrossRef Lentle B et al (2019) The radiology of osteoporotic vertebral fractures revisited. J Bone Miner Res 34(3):409–418PubMedCrossRef
30.
go back to reference Pinedo-Villanueva R et al (2019) Imminent fracture risk assessments in the UK FLS setting: implications and challenges. Archive Osteoporos Pinedo-Villanueva R et al (2019) Imminent fracture risk assessments in the UK FLS setting: implications and challenges. Archive Osteoporos
31.
go back to reference van den Berg P, van Haard P, Geusens PP, van den Bergh J, Schweitzer DH (2019) Challenges and opportunities to improve fracture liaison service attendance: fracture registration and patient characteristics and motivations. Osteoporos Int 30(8):1597–1606PubMedCrossRef van den Berg P, van Haard P, Geusens PP, van den Bergh J, Schweitzer DH (2019) Challenges and opportunities to improve fracture liaison service attendance: fracture registration and patient characteristics and motivations. Osteoporos Int 30(8):1597–1606PubMedCrossRef
32.
go back to reference Spechbach H, Fabreguet I, Saule E, Hars M, Stirnemann J, Ferrari S, Rizzoli R, Chevalley T (2019) Higher rates of osteoporosis treatment initiation and persistence in patients with newly diagnosed vertebral fracture when introduced in inpatients than later in outpatients. Osteoporos Int 30(7):1353–1362PubMedCrossRef Spechbach H, Fabreguet I, Saule E, Hars M, Stirnemann J, Ferrari S, Rizzoli R, Chevalley T (2019) Higher rates of osteoporosis treatment initiation and persistence in patients with newly diagnosed vertebral fracture when introduced in inpatients than later in outpatients. Osteoporos Int 30(7):1353–1362PubMedCrossRef
33.
go back to reference Densitometry, T.i.S.F.C. (2019) 2019 ISCD Official Positions Adult Densitometry, T.i.S.F.C. (2019) 2019 ISCD Official Positions Adult
34.
go back to reference Cummings SR et al (1993) Bone density at various sites for prediction of hip fractures. The Study of Osteoporotic Fractures Research Group. Lancet 341(8837):72–75PubMedCrossRef Cummings SR et al (1993) Bone density at various sites for prediction of hip fractures. The Study of Osteoporotic Fractures Research Group. Lancet 341(8837):72–75PubMedCrossRef
35.
go back to reference Diez-Perez A, Adachi JD, Agnusdei D, Bilezikian JP, Compston JE, Cummings SR, Eastell R, Eriksen EF, Gonzalez-Macias J, Liberman UA, Wahl DA, Seeman E, Kanis JA, Cooper C, IOF CSA Inadequate Responders Working Group (2012) Treatment failure in osteoporosis. Osteoporos Int 23(12):2769–2774PubMedCrossRef Diez-Perez A, Adachi JD, Agnusdei D, Bilezikian JP, Compston JE, Cummings SR, Eastell R, Eriksen EF, Gonzalez-Macias J, Liberman UA, Wahl DA, Seeman E, Kanis JA, Cooper C, IOF CSA Inadequate Responders Working Group (2012) Treatment failure in osteoporosis. Osteoporos Int 23(12):2769–2774PubMedCrossRef
36.
go back to reference NICE (2008) Alendronate, etidronate, risedronate, raloxifene, strontium ranelate and teriparatide for the secondary prevention of osteoporotic fragility fractures in postmenopausal women, in NICE Technology Appraisal guidance 161, N.I.f.H.a.C. Excellence, Editor. NICE, London NICE (2008) Alendronate, etidronate, risedronate, raloxifene, strontium ranelate and teriparatide for the secondary prevention of osteoporotic fragility fractures in postmenopausal women, in NICE Technology Appraisal guidance 161, N.I.f.H.a.C. Excellence, Editor. NICE, London
38.
go back to reference Kim J, Hwang JY, Oh JK, Park MS, Kim SW, Chang H, Kim TH (2017) The association between whole body sagittal balance and risk of falls among elderly patients seeking treatment for back pain. Bone Joint Res 6(5):337–344PubMedPubMedCentralCrossRef Kim J, Hwang JY, Oh JK, Park MS, Kim SW, Chang H, Kim TH (2017) The association between whole body sagittal balance and risk of falls among elderly patients seeking treatment for back pain. Bone Joint Res 6(5):337–344PubMedPubMedCentralCrossRef
39.
go back to reference Palumbo P et al (2016) Predictive performance of a fall risk assessment tool for community-dwelling older people (FRAT-up) in 4 European cohorts. J Am Med Dir Assoc 17(12):1106–1113PubMedPubMedCentralCrossRef Palumbo P et al (2016) Predictive performance of a fall risk assessment tool for community-dwelling older people (FRAT-up) in 4 European cohorts. J Am Med Dir Assoc 17(12):1106–1113PubMedPubMedCentralCrossRef
40.
go back to reference Podsiadlo D, Richardson S (1991) The timed “up & go”: a test of basic functional mobility for frail elderly persons. J Am Geriatr Soc 39(2):142–148CrossRef Podsiadlo D, Richardson S (1991) The timed “up & go”: a test of basic functional mobility for frail elderly persons. J Am Geriatr Soc 39(2):142–148CrossRef
41.
go back to reference Ensrud KE et al (2019) Association of disease definition, comorbidity burden, and prognosis with hip fracture probability among late-life women. JAMA Intern Med Ensrud KE et al (2019) Association of disease definition, comorbidity burden, and prognosis with hip fracture probability among late-life women. JAMA Intern Med
42.
go back to reference Ahmed LA, Nguyen ND, Bjørnerem Å, Joakimsen RM, Jørgensen L, Størmer J, Bliuc D, Center JR, Eisman JA, Nguyen TV, Emaus N (2014) External validation of the Garvan nomograms for predicting absolute fracture risk: the Tromsø study. PLoS One 9(9):e107695–e107695PubMedPubMedCentralCrossRef Ahmed LA, Nguyen ND, Bjørnerem Å, Joakimsen RM, Jørgensen L, Størmer J, Bliuc D, Center JR, Eisman JA, Nguyen TV, Emaus N (2014) External validation of the Garvan nomograms for predicting absolute fracture risk: the Tromsø study. PLoS One 9(9):e107695–e107695PubMedPubMedCentralCrossRef
43.
go back to reference Sherrington C et al (2019) Exercise for preventing falls in older people living in the community. Cochrane Database Syst Rev 1:Cd012424PubMed Sherrington C et al (2019) Exercise for preventing falls in older people living in the community. Cochrane Database Syst Rev 1:Cd012424PubMed
44.
go back to reference NICE (2009) Medicines adherence: involving patients in decisions about prescribing medicines and supporting adherence: Clinical Guideline 76 NICE (2009) Medicines adherence: involving patients in decisions about prescribing medicines and supporting adherence: Clinical Guideline 76
45.
go back to reference Højsager FD et al (2019) Fracture-induced changes in biomarkers CTX, PINP, OC, and BAP-a systematic review. Osteoporos Int 30(12):2381–2389PubMedCrossRef Højsager FD et al (2019) Fracture-induced changes in biomarkers CTX, PINP, OC, and BAP-a systematic review. Osteoporos Int 30(12):2381–2389PubMedCrossRef
46.
go back to reference de Bruin IJA, Wyers CE, van den Bergh J, Geusens PPMM (2017) Fracture liaison services: do they reduce fracture rates? Ther Adv Musculoskelet Dis 9(7):157–164PubMedPubMedCentralCrossRef de Bruin IJA, Wyers CE, van den Bergh J, Geusens PPMM (2017) Fracture liaison services: do they reduce fracture rates? Ther Adv Musculoskelet Dis 9(7):157–164PubMedPubMedCentralCrossRef
47.
go back to reference van den Berg P et al (2015) Meeting international standards of secondary fracture prevention: a survey on Fracture Liaison Services in the Netherlands. Osteoporos Int 26(9):2257–2263PubMedCrossRef van den Berg P et al (2015) Meeting international standards of secondary fracture prevention: a survey on Fracture Liaison Services in the Netherlands. Osteoporos Int 26(9):2257–2263PubMedCrossRef
48.
go back to reference Newman ED (2011) Perspectives on pre-fracture intervention strategies: the Geisinger Health System Osteoporosis Program. Osteoporos Int 22(Suppl 3):451–455PubMedCrossRef Newman ED (2011) Perspectives on pre-fracture intervention strategies: the Geisinger Health System Osteoporosis Program. Osteoporos Int 22(Suppl 3):451–455PubMedCrossRef
49.
go back to reference (2019) Effective secondary prevention of fragility fractures: clinical standards for fracture liaison services. Royal Osteoporosis Society (2019) Effective secondary prevention of fragility fractures: clinical standards for fracture liaison services. Royal Osteoporosis Society
50.
go back to reference Innovation, N.S.W.A.f.C. (2018) Model of care for osteoporotic refracture prevention, M. Network, Editor. ACI, Chatswood Innovation, N.S.W.A.f.C. (2018) Model of care for osteoporotic refracture prevention, M. Network, Editor. ACI, Chatswood
51.
go back to reference Kanis JA, Harvey NC, Cooper C, Johansson H, Odén A, McCloskey E, Advisory Board of the National Osteoporosis Guideline Group (2016) A systematic review of intervention thresholds based on FRAX : a report prepared for the National Osteoporosis Guideline Group and the International Osteoporosis Foundation. Arch Osteoporos 11(1):25PubMedPubMedCentralCrossRef Kanis JA, Harvey NC, Cooper C, Johansson H, Odén A, McCloskey E, Advisory Board of the National Osteoporosis Guideline Group (2016) A systematic review of intervention thresholds based on FRAX : a report prepared for the National Osteoporosis Guideline Group and the International Osteoporosis Foundation. Arch Osteoporos 11(1):25PubMedPubMedCentralCrossRef
52.
go back to reference Shepstone L et al (2016) A randomized controlled trial of screening in the community to reduce fractures in older women in the UK (The Scoop Study). Osteoporos Int 27:S1:21 Shepstone L et al (2016) A randomized controlled trial of screening in the community to reduce fractures in older women in the UK (The Scoop Study). Osteoporos Int 27:S1:21
53.
go back to reference Hippisley-Cox J, Coupland C (2012) Derivation and validation of updated QFracture algorithm to predict risk of osteoporotic fracture in primary care in the United Kingdom: prospective open cohort study. BMJ 344(may22 1):e3427CrossRefPubMed Hippisley-Cox J, Coupland C (2012) Derivation and validation of updated QFracture algorithm to predict risk of osteoporotic fracture in primary care in the United Kingdom: prospective open cohort study. BMJ 344(may22 1):e3427CrossRefPubMed
54.
go back to reference Bolland MJ et al (2011) Evaluation of the FRAX and Garvan fracture risk calculators in older women. J Bone Miner Res 26(2):420–427PubMedCrossRef Bolland MJ et al (2011) Evaluation of the FRAX and Garvan fracture risk calculators in older women. J Bone Miner Res 26(2):420–427PubMedCrossRef
55.
go back to reference Freemantle N, Cooper C, Diez-Perez A, Gitlin M, Radcliffe H, Shepherd S, Roux C (2013) Results of indirect and mixed treatment comparison of fracture efficacy for osteoporosis treatments: a meta-analysis. Osteoporos Int 24(1):209–217PubMedCrossRef Freemantle N, Cooper C, Diez-Perez A, Gitlin M, Radcliffe H, Shepherd S, Roux C (2013) Results of indirect and mixed treatment comparison of fracture efficacy for osteoporosis treatments: a meta-analysis. Osteoporos Int 24(1):209–217PubMedCrossRef
56.
go back to reference Miller PD, Hattersley G, Riis BJ, Williams GC, Lau E, Russo LA, Alexandersen P, Zerbini CA, Hu MY, Harris AG, Fitzpatrick LA, Cosman F, Christiansen C, ACTIVE Study Investigators (2016) Effect of abaloparatide vs placebo on new vertebral fractures in postmenopausal women with osteoporosis: a randomized clinical trial. Jama 316(7):722–733PubMedCrossRef Miller PD, Hattersley G, Riis BJ, Williams GC, Lau E, Russo LA, Alexandersen P, Zerbini CA, Hu MY, Harris AG, Fitzpatrick LA, Cosman F, Christiansen C, ACTIVE Study Investigators (2016) Effect of abaloparatide vs placebo on new vertebral fractures in postmenopausal women with osteoporosis: a randomized clinical trial. Jama 316(7):722–733PubMedCrossRef
57.
go back to reference Javaid MK et al (2016) Fracture Liaison Service (FLS) Database facilities audit. FLS breakpoint: opportunities for improving patient care following a fragility fracture. Royal College of Physicians, London Javaid MK et al (2016) Fracture Liaison Service (FLS) Database facilities audit. FLS breakpoint: opportunities for improving patient care following a fragility fracture. Royal College of Physicians, London
58.
go back to reference Sanli I, van Helden S, ten Broeke R, Geusens P, van den Bergh J, Brink PRG, Poeze M (2019) The role of the fracture liaison service (FLS) in subsequent fracture prevention in the extreme elderly. Aging Clin Exp Res 31(8):1105–1111PubMedCrossRef Sanli I, van Helden S, ten Broeke R, Geusens P, van den Bergh J, Brink PRG, Poeze M (2019) The role of the fracture liaison service (FLS) in subsequent fracture prevention in the extreme elderly. Aging Clin Exp Res 31(8):1105–1111PubMedCrossRef
59.
go back to reference von Friesendorff M, Besjakov J, Akesson K (2008) Long-term survival and fracture risk after hip fracture: a 22-year follow-up in women. J Bone Miner Res 23(11):1832–1841CrossRef von Friesendorff M, Besjakov J, Akesson K (2008) Long-term survival and fracture risk after hip fracture: a 22-year follow-up in women. J Bone Miner Res 23(11):1832–1841CrossRef
60.
go back to reference (1998) Guidelines for preclinical evaluation and clinical trials in osteoporosis, W.H. Organization, Editor. WHO Library Cataloguing, Geneva (1998) Guidelines for preclinical evaluation and clinical trials in osteoporosis, W.H. Organization, Editor. WHO Library Cataloguing, Geneva
61.
go back to reference Mitchell RM et al (2017) Reporting of vertebral fragility fractures: can radiologists help reduce the number of hip fractures? Arch Osteoporos 12(1):71PubMedPubMedCentralCrossRef Mitchell RM et al (2017) Reporting of vertebral fragility fractures: can radiologists help reduce the number of hip fractures? Arch Osteoporos 12(1):71PubMedPubMedCentralCrossRef
62.
go back to reference Fink HA, Milavetz DL, Palermo L, Nevitt MC, Cauley JA, Genant HK, Black DM, Ensrud KE, Fracture Intervention Trial Research Group (2005) What proportion of incident radiographic vertebral deformities is clinically diagnosed and vice versa? J Bone Miner Res 20(7):1216–1222PubMedCrossRef Fink HA, Milavetz DL, Palermo L, Nevitt MC, Cauley JA, Genant HK, Black DM, Ensrud KE, Fracture Intervention Trial Research Group (2005) What proportion of incident radiographic vertebral deformities is clinically diagnosed and vice versa? J Bone Miner Res 20(7):1216–1222PubMedCrossRef
63.
go back to reference Adams J et al (2017) Clinical guideline for the effective identification of vertebral fractures. Royal Osteoporosis Society Adams J et al (2017) Clinical guideline for the effective identification of vertebral fractures. Royal Osteoporosis Society
64.
go back to reference Black DM et al (1996) Randomised trial of effect of alendronate on risk of fracture in women with existing vertebral fractures. Fracture Intervention Trial Research Group. Lancet 348(9041):1535–1541PubMedCrossRef Black DM et al (1996) Randomised trial of effect of alendronate on risk of fracture in women with existing vertebral fractures. Fracture Intervention Trial Research Group. Lancet 348(9041):1535–1541PubMedCrossRef
65.
go back to reference Harris ST, Watts NB, Genant HK, McKeever C, Hangartner T, Keller M, Chesnut CH 3rd, Brown J, Eriksen EF, Hoseyni MS, Axelrod DW, Miller PD (1999) Effects of risedronate treatment on vertebral and nonvertebral fractures in women with postmenopausal osteoporosis: a randomized controlled trial. Vertebral Efficacy With Risedronate Therapy (VERT) Study Group. JAMA 282(14):1344–1352PubMedCrossRef Harris ST, Watts NB, Genant HK, McKeever C, Hangartner T, Keller M, Chesnut CH 3rd, Brown J, Eriksen EF, Hoseyni MS, Axelrod DW, Miller PD (1999) Effects of risedronate treatment on vertebral and nonvertebral fractures in women with postmenopausal osteoporosis: a randomized controlled trial. Vertebral Efficacy With Risedronate Therapy (VERT) Study Group. JAMA 282(14):1344–1352PubMedCrossRef
66.
go back to reference Senay A, Perreault S, Delisle J, Morin SN, Raynauld JP, Banica A, Troyanov Y, Beaumont P, Jodoin A, Laflamme GY, Leduc S, Mac-Thiong JM, Nguyen H, Ranger P, Rouleau DM, Fernandes JC (2019) Rationale, study design, and descriptive data of the Lucky Bone Fracture Liaison Service. Arch Osteoporos 14(1):19PubMedCrossRef Senay A, Perreault S, Delisle J, Morin SN, Raynauld JP, Banica A, Troyanov Y, Beaumont P, Jodoin A, Laflamme GY, Leduc S, Mac-Thiong JM, Nguyen H, Ranger P, Rouleau DM, Fernandes JC (2019) Rationale, study design, and descriptive data of the Lucky Bone Fracture Liaison Service. Arch Osteoporos 14(1):19PubMedCrossRef
67.
go back to reference Wu CH et al (2018) Fracture liaison services improve outcomes of patients with osteoporosis-related fractures: a systematic literature review and meta-analysis. Bone Wu CH et al (2018) Fracture liaison services improve outcomes of patients with osteoporosis-related fractures: a systematic literature review and meta-analysis. Bone
68.
go back to reference Ruggiero C, Zampi E, Rinonapoli G, Baroni M, Serra R, Zengarini E, Baglioni G, Duranti G, Ercolani S, Conti F, Caraffa A, Mecocci P, Brandi ML (2015) Fracture prevention service to bridge the osteoporosis care gap. Clin Interv Aging 10:1035–1042PubMedPubMedCentral Ruggiero C, Zampi E, Rinonapoli G, Baroni M, Serra R, Zengarini E, Baglioni G, Duranti G, Ercolani S, Conti F, Caraffa A, Mecocci P, Brandi ML (2015) Fracture prevention service to bridge the osteoporosis care gap. Clin Interv Aging 10:1035–1042PubMedPubMedCentral
69.
go back to reference Ganda K, Schaffer A, Pearson S, Seibel MJ (2014) Compliance and persistence to oral bisphosphonate therapy following initiation within a secondary fracture prevention program: a randomised controlled trial of specialist vs. non-specialist management. Osteoporos Int 25(4):1345–1355PubMedCrossRef Ganda K, Schaffer A, Pearson S, Seibel MJ (2014) Compliance and persistence to oral bisphosphonate therapy following initiation within a secondary fracture prevention program: a randomised controlled trial of specialist vs. non-specialist management. Osteoporos Int 25(4):1345–1355PubMedCrossRef
70.
go back to reference Dunn P, Webb D, Olenginski TP (2018) Geisinger high-risk osteoporosis clinic (HiROC): 2013-2015 FLS performance analysis. Osteoporos Int 29(2):451–457PubMedCrossRef Dunn P, Webb D, Olenginski TP (2018) Geisinger high-risk osteoporosis clinic (HiROC): 2013-2015 FLS performance analysis. Osteoporos Int 29(2):451–457PubMedCrossRef
71.
go back to reference Chandran M, Cheen M, Ying H, Lau TC, Tan M (2016) Dropping the ball and falling off the care wagon. Factors correlating with nonadherence to secondary fracture prevention programs. J Clin Densitom 19(1):117–124PubMedCrossRef Chandran M, Cheen M, Ying H, Lau TC, Tan M (2016) Dropping the ball and falling off the care wagon. Factors correlating with nonadherence to secondary fracture prevention programs. J Clin Densitom 19(1):117–124PubMedCrossRef
72.
go back to reference McAlister FA et al (2019) Adherence to osteoporosis therapy after an upper extremity fracture: a pre-specified substudy of the C-STOP randomized controlled trial. Osteoporos Int 30(1):127–134PubMedCrossRef McAlister FA et al (2019) Adherence to osteoporosis therapy after an upper extremity fracture: a pre-specified substudy of the C-STOP randomized controlled trial. Osteoporos Int 30(1):127–134PubMedCrossRef
73.
go back to reference Vaculik J et al (2017) Secondary fracture prevention in hip fracture patients requires cooperation from general practitioners. Arch Osteoporos 12(1):49PubMedCrossRef Vaculik J et al (2017) Secondary fracture prevention in hip fracture patients requires cooperation from general practitioners. Arch Osteoporos 12(1):49PubMedCrossRef
74.
go back to reference Gillespie LD et al (2012) Interventions for preventing falls in older people living in the community. Cochrane Database Syst Rev (9):Cd007146 Gillespie LD et al (2012) Interventions for preventing falls in older people living in the community. Cochrane Database Syst Rev (9):Cd007146
75.
go back to reference Hawley S, Javaid MK, Prieto-Alhambra D, Lippett J, Sheard S, Arden NK, Cooper C, Judge A, REFReSH study group (2016) Clinical effectiveness of orthogeriatric and fracture liaison service models of care for hip fracture patients: population-based longitudinal study. Age Ageing 45(2):236–242PubMedPubMedCentralCrossRef Hawley S, Javaid MK, Prieto-Alhambra D, Lippett J, Sheard S, Arden NK, Cooper C, Judge A, REFReSH study group (2016) Clinical effectiveness of orthogeriatric and fracture liaison service models of care for hip fracture patients: population-based longitudinal study. Age Ageing 45(2):236–242PubMedPubMedCentralCrossRef
76.
go back to reference Malgo F et al (2016) High prevalence of secondary factors for bone fragility in patients with a recent fracture independently of BMD. Arch Osteoporos 11:12PubMedPubMedCentralCrossRef Malgo F et al (2016) High prevalence of secondary factors for bone fragility in patients with a recent fracture independently of BMD. Arch Osteoporos 11:12PubMedPubMedCentralCrossRef
77.
go back to reference Gallagher JC, Sai A, Templin T 2nd, Smith L (2012) Dose response to vitamin D supplementation in postmenopausal women: a randomized trial. Ann Intern Med 156(6):425–437PubMedCrossRef Gallagher JC, Sai A, Templin T 2nd, Smith L (2012) Dose response to vitamin D supplementation in postmenopausal women: a randomized trial. Ann Intern Med 156(6):425–437PubMedCrossRef
78.
go back to reference Hypponen E, Power C (2007) Hypovitaminosis D in British adults at age 45 y: nationwide cohort study of dietary and lifestyle predictors. Am J Clin Nutr 85(3):860–868PubMedCrossRef Hypponen E, Power C (2007) Hypovitaminosis D in British adults at age 45 y: nationwide cohort study of dietary and lifestyle predictors. Am J Clin Nutr 85(3):860–868PubMedCrossRef
79.
go back to reference Bours PHA et al (2011) Seasonal variation of serum 25-hydroxyvitamin D levels in adult patients with inflammatory bowel disease. Osteoporos Int 22(11):2857–2867PubMedCrossRef Bours PHA et al (2011) Seasonal variation of serum 25-hydroxyvitamin D levels in adult patients with inflammatory bowel disease. Osteoporos Int 22(11):2857–2867PubMedCrossRef
80.
go back to reference Reid D, Toole BJ, Knox S, Talwar D, Harten J, O’Reilly DS, Blackwell S, Kinsella J, McMillan D, Wallace AM (2011) The relation between acute changes in the systemic inflammatory response and plasma 25-hydroxyvitamin D concentrations after elective knee arthroplasty. Am J Clin Nutr 93(5):1006–1011PubMedCrossRef Reid D, Toole BJ, Knox S, Talwar D, Harten J, O’Reilly DS, Blackwell S, Kinsella J, McMillan D, Wallace AM (2011) The relation between acute changes in the systemic inflammatory response and plasma 25-hydroxyvitamin D concentrations after elective knee arthroplasty. Am J Clin Nutr 93(5):1006–1011PubMedCrossRef
81.
go back to reference Francis R et al (2013) Vitamin D and bone health: a practical clinical guideline for patient management. National Osteoporosis Society Francis R et al (2013) Vitamin D and bone health: a practical clinical guideline for patient management. National Osteoporosis Society
82.
go back to reference Burt LA, Billington EO, Rose MS, Raymond DA, Hanley DA, Boyd SK (2019) Effect of high-dose vitamin D supplementation on volumetric bone density and bone strength: a randomized clinical trial. Jama 322(8):736–745PubMedPubMedCentralCrossRef Burt LA, Billington EO, Rose MS, Raymond DA, Hanley DA, Boyd SK (2019) Effect of high-dose vitamin D supplementation on volumetric bone density and bone strength: a randomized clinical trial. Jama 322(8):736–745PubMedPubMedCentralCrossRef
83.
go back to reference Grant AM, Avenell A, Campbell MK, McDonald A, MacLennan G, McPherson G, Anderson FH, Cooper C, Francis RM, Donaldson C, Gillespie WJ, Robinson CM, Torgerson DJ, Wallace WA, RECORD Trial Group (2005) Oral vitamin D3 and calcium for secondary prevention of low-trauma fractures in elderly people (Randomised Evaluation of Calcium Or vitamin D, RECORD): a randomised placebo-controlled trial. Lancet 365(9471):1621–1628PubMedCrossRef Grant AM, Avenell A, Campbell MK, McDonald A, MacLennan G, McPherson G, Anderson FH, Cooper C, Francis RM, Donaldson C, Gillespie WJ, Robinson CM, Torgerson DJ, Wallace WA, RECORD Trial Group (2005) Oral vitamin D3 and calcium for secondary prevention of low-trauma fractures in elderly people (Randomised Evaluation of Calcium Or vitamin D, RECORD): a randomised placebo-controlled trial. Lancet 365(9471):1621–1628PubMedCrossRef
84.
85.
go back to reference Mitchell PJ et al (2019) Quality improvement initiatives in fragility fracture care and prevention. Curr Osteoporos Rep 17(6):510–520PubMedCrossRef Mitchell PJ et al (2019) Quality improvement initiatives in fragility fracture care and prevention. Curr Osteoporos Rep 17(6):510–520PubMedCrossRef
Metadata
Title
A patient-level key performance indicator set to measure the effectiveness of fracture liaison services and guide quality improvement: a position paper of the IOF Capture the Fracture Working Group, National Osteoporosis Foundation and Fragility Fracture Network
Authors
M. K. Javaid
A. Sami
W. Lems
P. Mitchell
T. Thomas
A. Singer
R. Speerin
M. Fujita
D. D. Pierroz
K. Akesson
P. Halbout
S. Ferrari
C. Cooper
Publication date
01-07-2020
Publisher
Springer London
Published in
Osteoporosis International / Issue 7/2020
Print ISSN: 0937-941X
Electronic ISSN: 1433-2965
DOI
https://doi.org/10.1007/s00198-020-05377-1

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