Skip to main content
Top
Published in: Osteoporosis International 11/2012

Open Access 01-11-2012 | Original Article

The burden of illness of osteoporosis in Canada

Authors: J.-E. Tarride, R. B. Hopkins, W. D. Leslie, S. Morin, J. D. Adachi, A. Papaioannou, L. Bessette, J. P. Brown, R. Goeree

Published in: Osteoporosis International | Issue 11/2012

Login to get access

Abstract

Summary

To update the 1993 burden of illness of osteoporosis in Canada, administrative and community data were used to calculate the 2010 costs of osteoporosis at $2.3 billion in Canada or 1.3% of Canada’s healthcare expenditures. Prevention of fractures in high-risk individuals is key to decrease the financial burden of osteoporosis.

Introduction

Since the 1996 publication of the burden of osteoporosis in 1993 in Canada, the population has aged and the management of osteoporosis has changed. The study purpose was to estimate the current burden of illness due to osteoporosis in Canadians aged 50 and over.

Methods

Analyses were conducted using five national administrative databases from the Canadian Institute for Health Information for the fiscal-year ending March 31 2008 (FY 2007/2008). Gaps in national data were supplemented by provincial and community data extrapolated to national levels. Osteoporosis-related fractures were identified using a combination of most responsible diagnosis at discharge and intervention codes. Fractures associated with severe trauma codes were excluded. Costs, expressed in 2010 dollars, were calculated for osteoporosis-related hospitalizations, emergency care, same day surgeries, rehabilitation, continuing care, homecare, long-term care, prescription drugs, physician visits, and productivity losses. Sensitivity analyses were conducted to measure the impact on the results of key assumptions.

Results

Osteoporosis-related fractures were responsible for 57,413 acute care admissions and 832,594 hospitalized days in FY 2007/2008. Acute care costs were estimated at $1.2 billion. When outpatient care, prescription drugs, and indirect costs were added, the overall yearly cost of osteoporosis was over $2.3 billion for the base case analysis and as much as $3.9 billion if a proportion of Canadians were assumed to be living in long-term care facilities due to osteoporosis.

Conclusions

Osteoporosis is a chronic disease that affects a large segment of the adult population and results in a substantial economic burden to the Canadian society.
Appendix
Available only for authorised users
Literature
1.
go back to reference Papaioannou A, Morin S, Cheung AM, Atkinson S, Brown JP, Feldman S, Hanley DA, Hodsman A, Jamal SA, Kaiser SM et al (2010) 2010 clinical practice guidelines for the diagnosis and management of osteoporosis in Canada: summary. CMAJ 182(17):1864–1873PubMedCrossRef Papaioannou A, Morin S, Cheung AM, Atkinson S, Brown JP, Feldman S, Hanley DA, Hodsman A, Jamal SA, Kaiser SM et al (2010) 2010 clinical practice guidelines for the diagnosis and management of osteoporosis in Canada: summary. CMAJ 182(17):1864–1873PubMedCrossRef
2.
go back to reference Brown JP, Josse RG (2002) 2002 clinical practice guidelines for the diagnosis and management of osteoporosis in Canada. CMAJ 167(10 Suppl):S1–S34PubMed Brown JP, Josse RG (2002) 2002 clinical practice guidelines for the diagnosis and management of osteoporosis in Canada. CMAJ 167(10 Suppl):S1–S34PubMed
3.
go back to reference Statistics Canada (2010) Estimates of population, by age group and sex for July 1, Canada, provinces and territories, annual. Table 051–0001 Statistics Canada (2010) Estimates of population, by age group and sex for July 1, Canada, provinces and territories, annual. Table 051–0001
4.
go back to reference Goeree R, O'Brien B, Pettitt D, Cuddy L, Ferraz M, Adachi JD (1996) An assessment of the burden of illness due to osteoporosis in Canada. J Soc Obstet Gynaecol Can 18(Suppl July):15–24 Goeree R, O'Brien B, Pettitt D, Cuddy L, Ferraz M, Adachi JD (1996) An assessment of the burden of illness due to osteoporosis in Canada. J Soc Obstet Gynaecol Can 18(Suppl July):15–24
5.
go back to reference Statistics Canada (2011) Consumer Price Index (CPI) Statistics. Table 176–000 Statistics Canada (2011) Consumer Price Index (CPI) Statistics. Table 176–000
6.
go back to reference Canadian Institute for Health Information (2006) Discharge Abstract Database (DAD) Abstracting Manual, 2007–2008 Edition (Ottawa: CIHI, 2006) Canadian Institute for Health Information (2006) Discharge Abstract Database (DAD) Abstracting Manual, 2007–2008 Edition (Ottawa: CIHI, 2006)
7.
go back to reference Canadian Institute for Health Information (2010) National Ambulatory Care Reporting System (NACRS), Database Background and General Data Limitations Documentation,, 2007–2008 (Ottawa, Ont.: CIHI, 2008) Canadian Institute for Health Information (2010) National Ambulatory Care Reporting System (NACRS), Database Background and General Data Limitations Documentation,, 2007–2008 (Ottawa, Ont.: CIHI, 2008)
8.
go back to reference Canadian Institute for Health Information (2010) National Rehabilitation Reporting System (NRS) Data Quality Documentation 2007–2008 (Ottawa, Ont.: CIHI, 2009) Canadian Institute for Health Information (2010) National Rehabilitation Reporting System (NRS) Data Quality Documentation 2007–2008 (Ottawa, Ont.: CIHI, 2009)
9.
go back to reference Canadian Institute for Health Information (2010) Home Care Reporting System Canadian Institute for Health Information (2010) Home Care Reporting System
10.
go back to reference Canadian Institute for Health Information (2010) Continuing Care Reporting System (CCRS) Specifications Manual, 2009 (Ottawa, Ont.: CIHI, 2008) Canadian Institute for Health Information (2010) Continuing Care Reporting System (CCRS) Specifications Manual, 2009 (Ottawa, Ont.: CIHI, 2008)
11.
go back to reference Intercontinental Marketing Services (IMS) Health Canada (2010) Intercontinental Marketing Services (IMS) Health Canada (2010)
12.
go back to reference IMS Brogan (2010) Brogan PharmaStat ® Database. Pharmaceutical Market Data IMS Brogan (2010) Brogan PharmaStat ® Database. Pharmaceutical Market Data
13.
go back to reference Kreiger N, Joseph L, Mackenzie T, Poliquin S, Brown J, Prior J, Rittmaster R, Tenenhouse A (1999) The Canadian Multicentre Osteoporosis Study (CaMos): background, rationale, methods. Can J Aging 18(3):376–387CrossRef Kreiger N, Joseph L, Mackenzie T, Poliquin S, Brown J, Prior J, Rittmaster R, Tenenhouse A (1999) The Canadian Multicentre Osteoporosis Study (CaMos): background, rationale, methods. Can J Aging 18(3):376–387CrossRef
14.
go back to reference Statistics Canada (2010) Labour force survey estimates (LFS), wages of employees by type of work, National Occupational Classification for Statistics (NOC-S), sex and age group Statistics Canada (2010) Labour force survey estimates (LFS), wages of employees by type of work, National Occupational Classification for Statistics (NOC-S), sex and age group
15.
go back to reference Statistics Canada (2010) Labour force survey estimates (LFS), by sex and detailed age group, annual Statistics Canada (2010) Labour force survey estimates (LFS), by sex and detailed age group, annual
16.
go back to reference Bessette L, Ste-Marie LG, Jean S, Davison KS, Beaulieu M, Baranci M, Bessant J, Brown JP (2008) Recognizing osteoporosis and its consequences in Quebec (ROCQ): background, rationale, and methods of an anti-fracture patient health-management programme. Contemp Clin Trials 29(2):194–210PubMedCrossRef Bessette L, Ste-Marie LG, Jean S, Davison KS, Beaulieu M, Baranci M, Bessant J, Brown JP (2008) Recognizing osteoporosis and its consequences in Quebec (ROCQ): background, rationale, and methods of an anti-fracture patient health-management programme. Contemp Clin Trials 29(2):194–210PubMedCrossRef
18.
go back to reference Mackey DC, Lui LY, Cawthon PM, Bauer DC, Nevitt MC, Cauley JA, Hillier TA, Lewis CE, Barrett-Connor E, Cummings SR (2007) High-trauma fractures and low bone mineral density in older women and men. JAMA 298(20):2381–2388PubMedCrossRef Mackey DC, Lui LY, Cawthon PM, Bauer DC, Nevitt MC, Cauley JA, Hillier TA, Lewis CE, Barrett-Connor E, Cummings SR (2007) High-trauma fractures and low bone mineral density in older women and men. JAMA 298(20):2381–2388PubMedCrossRef
19.
go back to reference Canadian Institute for Health Information (2010) Canadian MIS Database—Hospital Financial Performance Indicators, 1999–2000 to 2008–2009 Canadian Institute for Health Information (2010) Canadian MIS Database—Hospital Financial Performance Indicators, 1999–2000 to 2008–2009
20.
go back to reference Ontario Ministry of Health and Long Term Care (2010) Schedule of Benefits for Physician Services under the Health Insurance Act Ontario Ministry of Health and Long Term Care (2010) Schedule of Benefits for Physician Services under the Health Insurance Act
21.
go back to reference Kaffashian S, Raina P, Oremus M, Pickard L, Adachi J, Papadimitropoulos E, Papaioannou A (2011) The burden of osteoporotic fractures beyond acute care: the Canadian Multicentre Osteoporosis Study (CaMos). Age Ageing 40(5):602–607PubMedCrossRef Kaffashian S, Raina P, Oremus M, Pickard L, Adachi J, Papadimitropoulos E, Papaioannou A (2011) The burden of osteoporotic fractures beyond acute care: the Canadian Multicentre Osteoporosis Study (CaMos). Age Ageing 40(5):602–607PubMedCrossRef
22.
go back to reference Bessette L, Ste-Marie LG, Jean S, Davison KS, Beaulieu M, Baranci M, Bessant J, Brown JP (2008) The care gap in diagnosis and treatment of women with a fragility fracture. Osteoporos Int 19(1):79–86PubMedCrossRef Bessette L, Ste-Marie LG, Jean S, Davison KS, Beaulieu M, Baranci M, Bessant J, Brown JP (2008) The care gap in diagnosis and treatment of women with a fragility fracture. Osteoporos Int 19(1):79–86PubMedCrossRef
23.
go back to reference Medical Advisory Secretariat (2008) The Falls/Fractures Economic Model in Ontario Residents aged 65 Years and Over (FEMOR). Ont Health Technol Assess Ser 8(6) Medical Advisory Secretariat (2008) The Falls/Fractures Economic Model in Ontario Residents aged 65 Years and Over (FEMOR). Ont Health Technol Assess Ser 8(6)
24.
go back to reference Mackey DC, Black DM, Bauer DC, McCloskey EV, Eastell R, Mesenbrink P, Thompson JR, Cummings SR (2011) Effects of antiresorptive treatment on nonvertebral fracture outcomes. J Bone Miner Res 26(10):2411–2418PubMedCrossRef Mackey DC, Black DM, Bauer DC, McCloskey EV, Eastell R, Mesenbrink P, Thompson JR, Cummings SR (2011) Effects of antiresorptive treatment on nonvertebral fracture outcomes. J Bone Miner Res 26(10):2411–2418PubMedCrossRef
25.
go back to reference Papaioannou A, Kennedy CC, Ioannidis G, Sawka A, Hopman WM, Pickard L, Brown JP, Josse RG, Kaiser S, Anastassiades T et al (2009) The impact of incident fractures on health-related quality of life: 5 years of data from the Canadian Multicentre Osteoporosis Study. Osteoporos Int 20(5):703–714PubMedCrossRef Papaioannou A, Kennedy CC, Ioannidis G, Sawka A, Hopman WM, Pickard L, Brown JP, Josse RG, Kaiser S, Anastassiades T et al (2009) The impact of incident fractures on health-related quality of life: 5 years of data from the Canadian Multicentre Osteoporosis Study. Osteoporos Int 20(5):703–714PubMedCrossRef
26.
go back to reference Ioannidis G, Papaioannou A, Hopman WM, Akhtar-Danesh N, Anastassiades T, Pickard L, Kennedy CC, Prior JC, Olszynski WP, Davison KS et al (2009) Relation between fractures and mortality: results from the Canadian Multicentre Osteoporosis Study. CMAJ 181(5):265–271PubMedCrossRef Ioannidis G, Papaioannou A, Hopman WM, Akhtar-Danesh N, Anastassiades T, Pickard L, Kennedy CC, Prior JC, Olszynski WP, Davison KS et al (2009) Relation between fractures and mortality: results from the Canadian Multicentre Osteoporosis Study. CMAJ 181(5):265–271PubMedCrossRef
27.
go back to reference Canadian Institute for Health Information (2010) National Health Expenditure Trends,1975 to 2010 (Ottawa, Ont.: CIHI, 2010) Canadian Institute for Health Information (2010) National Health Expenditure Trends,1975 to 2010 (Ottawa, Ont.: CIHI, 2010)
28.
go back to reference Canadian Institute for Health Information (2009) Health Indicators 2009 (Ottawa, Ont.: CIHI, 2009) Canadian Institute for Health Information (2009) Health Indicators 2009 (Ottawa, Ont.: CIHI, 2009)
29.
go back to reference Blume SW, Curtis JR (2010) Medical costs of osteoporosis in the elderly Medicare population. Osteoporos Int Dec 17 Blume SW, Curtis JR (2010) Medical costs of osteoporosis in the elderly Medicare population. Osteoporos Int Dec 17
30.
go back to reference Brecht JG, Schadlich PK (2000) Burden of illness imposed by osteoporosis in Germany. HEPAC 1:26–32CrossRef Brecht JG, Schadlich PK (2000) Burden of illness imposed by osteoporosis in Germany. HEPAC 1:26–32CrossRef
31.
go back to reference Brown P, McNeill R, Leung W, Radwan E, Willingale J (2011) Current and future economic burden of osteoporosis in New Zealand. Appl Health Econ Health Policy 9(2):111–123PubMedCrossRef Brown P, McNeill R, Leung W, Radwan E, Willingale J (2011) Current and future economic burden of osteoporosis in New Zealand. Appl Health Econ Health Policy 9(2):111–123PubMedCrossRef
32.
go back to reference Clark P, Carlos F, Barrera C, Guzman J, Maetzel A, Lavielle P, Ramirez E, Robinson V, Rodriguez-Cabrera R, Tamayo J et al (2008) Direct costs of osteoporosis and hip fracture: an analysis for the Mexican healthcare system. Osteoporos Int 19(3):269–276PubMedCrossRef Clark P, Carlos F, Barrera C, Guzman J, Maetzel A, Lavielle P, Ramirez E, Robinson V, Rodriguez-Cabrera R, Tamayo J et al (2008) Direct costs of osteoporosis and hip fracture: an analysis for the Mexican healthcare system. Osteoporos Int 19(3):269–276PubMedCrossRef
33.
go back to reference Haussler B, Gothe H, Gol D, Glaeske G, Pientka L, Felsenberg D (2007) Epidemiology, treatment and costs of osteoporosis in Germany—the BoneEVA Study. Osteoporos Int 18(1):77–84PubMedCrossRef Haussler B, Gothe H, Gol D, Glaeske G, Pientka L, Felsenberg D (2007) Epidemiology, treatment and costs of osteoporosis in Germany—the BoneEVA Study. Osteoporos Int 18(1):77–84PubMedCrossRef
34.
go back to reference Johnell O, Kanis JA, Jonsson B, Oden A, Johansson H, De Laet C (2005) The burden of hospitalised fractures in Sweden. Osteoporos Int 16(2):222–228PubMedCrossRef Johnell O, Kanis JA, Jonsson B, Oden A, Johansson H, De Laet C (2005) The burden of hospitalised fractures in Sweden. Osteoporos Int 16(2):222–228PubMedCrossRef
35.
go back to reference Lippuner K, Golder M, Greiner R (2005) Epidemiology and direct medical costs of osteoporotic fractures in men and women in Switzerland. Osteoporos Int 16(Suppl 2):S8–S17PubMedCrossRef Lippuner K, Golder M, Greiner R (2005) Epidemiology and direct medical costs of osteoporotic fractures in men and women in Switzerland. Osteoporos Int 16(Suppl 2):S8–S17PubMedCrossRef
36.
go back to reference Maravic M, Le BC, Landais P, Fardellone P (2005) Incidence and cost of osteoporotic fractures in France during 2001. A methodological approach by the national hospital database. Osteoporos Int 16(12):1475–1480PubMedCrossRef Maravic M, Le BC, Landais P, Fardellone P (2005) Incidence and cost of osteoporotic fractures in France during 2001. A methodological approach by the national hospital database. Osteoporos Int 16(12):1475–1480PubMedCrossRef
37.
go back to reference Ray NF, Chan JK, Thamer M, Melton LJI (1997) Medical expenditures for the treatment of osteoporotic fractures in the United States in 1995: report from the National Osteoporosis Foundation. J Bone Miner Res 12(1):24–35PubMedCrossRef Ray NF, Chan JK, Thamer M, Melton LJI (1997) Medical expenditures for the treatment of osteoporotic fractures in the United States in 1995: report from the National Osteoporosis Foundation. J Bone Miner Res 12(1):24–35PubMedCrossRef
38.
go back to reference Bessette L, Jean S, Lapointe-Garant MP, Belzile EL, Davison KS, Ste-Marie LG, Brown JP (2011) Direct medical costs attributable to peripheral fractures in Canadian post-menopausal women. Osteoporos Int Sep 17 Bessette L, Jean S, Lapointe-Garant MP, Belzile EL, Davison KS, Ste-Marie LG, Brown JP (2011) Direct medical costs attributable to peripheral fractures in Canadian post-menopausal women. Osteoporos Int Sep 17
39.
go back to reference Leslie W, O'Donnell S, Lagace C, Walsh P, Bancej C, Jean S, Siminoski K, Kaiser S, Kendler D, Jaglal S et al (2010) Population-based Canadian hip fracture rates with international comparisons. Osteoporos Int 21(8):1317–1322PubMedCrossRef Leslie W, O'Donnell S, Lagace C, Walsh P, Bancej C, Jean S, Siminoski K, Kaiser S, Kendler D, Jaglal S et al (2010) Population-based Canadian hip fracture rates with international comparisons. Osteoporos Int 21(8):1317–1322PubMedCrossRef
Metadata
Title
The burden of illness of osteoporosis in Canada
Authors
J.-E. Tarride
R. B. Hopkins
W. D. Leslie
S. Morin
J. D. Adachi
A. Papaioannou
L. Bessette
J. P. Brown
R. Goeree
Publication date
01-11-2012
Publisher
Springer-Verlag
Published in
Osteoporosis International / Issue 11/2012
Print ISSN: 0937-941X
Electronic ISSN: 1433-2965
DOI
https://doi.org/10.1007/s00198-012-1931-z

Other articles of this Issue 11/2012

Osteoporosis International 11/2012 Go to the issue