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01-09-2020 | Computed Tomography | Original

Comparative study of lung ultrasound and chest computed tomography scan in the assessment of severity of confirmed COVID-19 pneumonia

Authors: Laurent Zieleskiewicz, Thibaut Markarian, Alexandre Lopez, Chloé Taguet, Neyla Mohammedi, Mohamed Boucekine, Karine Baumstarck, Guillaume Besch, Gautier Mathon, Gary Duclos, Lionel Bouvet, Pierre Michelet, Bernard Allaouchiche, Kathia Chaumoître, Mathieu Di Bisceglie, Marc Leone, on behalf of the AZUREA Network

Published in: Intensive Care Medicine | Issue 9/2020

Abstract

Purpose

The relationship between lung ultrasound (LUS) and chest computed tomography (CT) scans in patients with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pneumonia is not clearly defined. The primary objective of our study was to assess the performance of LUS in determining severity of SARS-CoV-2 pneumonia compared with chest CT scan. Secondary objectives were to test the association between LUS score and location of the patient, use of mechanical ventilation, and the pulse oximetry (SpO₂)/fractional inspired oxygen (FiO₂) ratio.

Methods

A multicentre observational study was performed between 15 March and 20 April 2020. Patients in the Emergency Department (ED) or Intensive Care Unit (ICU) with acute dyspnoea who were PCR positive for SARS-CoV-2, and who had LUS and chest CT performed within a 24-h period, were included.

Results

One hundred patients were included. LUS score was significantly associated with pneumonia severity assessed by chest CT and clinical features. The AUC of the ROC curve of the relationship of LUS versus chest CT for the assessment of severe SARS-CoV-2 pneumonia was 0.78 (CI 95% 0.68–0.87; p < 0.0001). A high LUS score was associated with the use of mechanical ventilation, and with a SpO₂/FiO₂ ratio below 357.

Conclusion

In known SARS-CoV-2 pneumonia patients, the LUS score was predictive of pneumonia severity as assessed by a chest CT scan and clinical features. Within the limitations inherent to our study design, LUS can be used to assess SARS-CoV-2 pneumonia severity.

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Title: Comparative study of lung ultrasound and chest computed tomography scan in the assessment of severity of confirmed COVID-19 pneumonia
Authors: Laurent Zieleskiewicz
Thibaut Markarian
Alexandre Lopez
Chloé Taguet
Neyla Mohammedi
Mohamed Boucekine
Karine Baumstarck
Guillaume Besch
Gautier Mathon
Gary Duclos
Lionel Bouvet
Pierre Michelet
Bernard Allaouchiche
Kathia Chaumoître
Mathieu Di Bisceglie
Marc Leone
on behalf of the AZUREA Network
Publication date: 01-09-2020
Publisher: Springer Berlin Heidelberg
Keywords: Computed Tomography
Computed Tomography
SARS-CoV-2
Pneumonia
COVID-19
Lung Ultrasound
Published in: Intensive Care Medicine / Issue 9/2020
Print ISSN: 0342-4642
Electronic ISSN: 1432-1238
DOI: https://doi.org/10.1007/s00134-020-06186-0

2024 ASCO Annual Meeting

Springer Medicine

Comparative study of lung ultrasound and chest computed tomography scan in the assessment of severity of confirmed COVID-19 pneumonia

Abstract

Purpose

Methods

Results

Conclusion

2024 ASCO Annual Meeting

Springer Medicine

Abstract

Purpose

Methods

Results

Conclusion

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