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Intensive Care Medicine

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01-11-2010 | Original

Fluid responsiveness predicted by noninvasive Bioreactance-based passive leg raise test

Authors: Brahim Benomar, Alexandre Ouattara, Philippe Estagnasie, Alain Brusset, Pierre Squara

Published in: Intensive Care Medicine | Issue 11/2010

Abstract

Purpose

To study the feasibility of predicting fluid responsiveness (FR) by passive leg raising (PLR) using a Bioreactance-based noninvasive cardiac output monitoring device (NICOM).

Method

This prospective, two-center study included 75 consecutive intensive care unit (ICU) adult patients immediately after cardiac surgery. NICOM was used to continuously record cardiac output (CO) at baseline, during a PLR, and then during a 500 ml i.v. rapid colloid infusion. We estimated the precision of NICOM at baseline to derive the least minimum significant change (LMSC) in CO. We studied the predictability of PLR for FR by systematic analysis of different categorizations of PLR and FR, based on percentage change in CO (from 0 to 20%).

Results

The LMSC was 8.85%. CO was 4.17 ± 1.04 L min⁻¹ at baseline, 4.38 ± 1.14 L min⁻¹ during PLR, 4.16 ± 1.08 L min⁻¹ upon return to baseline, and 4.85 ± 1.41 L min⁻¹ after fluid infusion. The change in CO following fluid bolus was highly correlated with the change in CO following PLR: y = 0.91x + 4.3, r = 0.77. The Pearson correlation coefficient showed that the best pair of thresholds was found for PLR ≥0% predicting FR ≥0%. Using this pair of thresholds, PLR had 88% sensitivity and 100% specificity for predicting FR. When we restricted the analysis to change in CO > LMSC, the best pair of thresholds was obtained for PLR >9% predicting FR >9%. Using this pair of thresholds, PLR sensitivity was reduced to 68% and specificity to 95%.

Conclusions

In this specific population of patients, it is clinically valid to use the bioreactance-based NICOM system to predict FR from changes in CO during PLR.

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Title: Fluid responsiveness predicted by noninvasive Bioreactance-based passive leg raise test
Authors: Brahim Benomar
Alexandre Ouattara
Philippe Estagnasie
Alain Brusset
Pierre Squara
Publication date: 01-11-2010
Publisher: Springer-Verlag
Published in: Intensive Care Medicine / Issue 11/2010
Print ISSN: 0342-4642
Electronic ISSN: 1432-1238
DOI: https://doi.org/10.1007/s00134-010-1990-6

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Fluid responsiveness predicted by noninvasive Bioreactance-based passive leg raise test

Abstract

Purpose

Method

Results

Conclusions

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Purpose

Method

Results

Conclusions

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