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01-07-2005 | Editorial

Does high tidal volume generate ALI/ARDS in healthy lungs?

Authors: Chiara Bonetto, Pierpaolo Terragni, V. Marco Ranieri

Published in: Intensive Care Medicine | Issue 7/2005

Excerpt

In Intensive Care Medicine Gajic and coworkers [1] now report that use for the first 48 h after ICU admission of high tidal volumes (>700 ml) and high peak inspiratory pressures (>30 cmH₂O) is associated with the development of the criteria for acute respiratory distress syndrome (ARDS) in patients requiring mechanical ventilation for surgery, aspiration, sepsis, pneumonia and trauma but who did not have ARDS. Do these results support the concept that stretch due to mechanical ventilation may cause ventilator-induced lung injury (VILI) in healthy lung [2]? …

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Sakr Y, Vincent J-L, Reinhart K, Groeneveld J, Michalopoulos A, Sprung CL, Artigas A, Ranieri VM on behalf of the “Sepsis Occurrence in Acutely Ill Patients” investigators (2005) High tidal volume and positive fluid balance are associated with worse outcome in acute lung injury Chest (in press)

Title: Does high tidal volume generate ALI/ARDS in healthy lungs?
Authors: Chiara Bonetto
Pierpaolo Terragni
V. Marco Ranieri
Publication date: 01-07-2005
Publisher: Springer-Verlag
Published in: Intensive Care Medicine / Issue 7/2005
Print ISSN: 0342-4642
Electronic ISSN: 1432-1238
DOI: https://doi.org/10.1007/s00134-005-2668-3

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Does high tidal volume generate ALI/ARDS in healthy lungs?

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