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31-01-2024 | Inflammatory Rheumatic Diseases | Review

Rehabilitation of patients with inflammatory rheumatic diseases and comorbidities: unmet needs

Authors: Yuliya Fedorchenko, Khaiyom Mahmudov, Zhumabek Abenov, Olena Zimba, Marlen Yessirkepov

Published in: Rheumatology International | Issue 4/2024

Abstract

Comorbidities may contribute to inadequate response to therapy and accelerate disability in various rheumatic diseases such as rheumatoid arthritis (RA), systemic lupus erythematosus (SLE), and psoriatic arthritis (PsA). Cardiovascular, oncological, and infectious comorbidities are common in rheumatic patients. The rehabilitation of patients with inflammatory rheumatic diseases (IRDs) with comorbidities requires a multidisciplinary approach to improving patients’ functional mobility, slowing down the disease progression and minimizing the risks of complications. The evidence suggests that cardiac rehabilitation can be implemented in daily practice in patients with IRDs to reduce mortality for those with established risk factors. Physical exercises reduce the severity, improve the clinical course, and reduce hospitalization rates in patients with rheumatic diseases. A rehabilitation program with focused physical therapy can lead to functional improvements and reduction of disease activity in patients with lowered quality of life (QoL). Health professionals should provide evidence-based recommendations for patients with rheumatic diseases and comorbidities to initiate the self-management of their diseases and prevent complications.

van den Hoek J, Boshuizen HC, Roorda LD, Tijhuis GJ, Nurmohamed MT, Dekker J et al (2016) Association of somatic comorbidities and comorbid depression with mortality in patients with rheumatoid arthritis: a 14-year prospective cohort study. Arthritis Care Res (Hoboken) 68(8):1055–1060. https://doi.org/10.1002/acr.22812CrossRefPubMed

Filipowicz-Sosnowska A (2019) Comorbidities and multimorbidity in rheumatic diseases. Reumatologia 57(1):1–2. https://doi.org/10.5114/reum.2019.83232CrossRefPubMedPubMedCentral

Gasparyan AY (2023) Cardiovascular manifestations and comorbidities in rheumatic diseases: perspectives on timely diagnosis, prevention, and treatment. Clin Rheumatol 42(10):2531–2533. https://doi.org/10.1007/s10067-023-06762-xCrossRefPubMed

Ferguson LD, Sattar N, McInnes IB (2021) Managing cardiovascular risk in patients with rheumatic disease. Med Clin North Am 105(2):247–262. https://doi.org/10.1016/j.mcna.2020.09.010CrossRefPubMed

Zimba O, Gasparyan AY (2023) Cardiovascular issues in rheumatic diseases. Clin Rheumatol 42(10):2535–2539. https://doi.org/10.1007/s10067-023-06656-yCrossRefPubMed

Recinella L, Orlando G, Ferrante C, Chiavaroli A, Brunetti L, Leone S (2020) Adipokines: new potential therapeutic target for obesity and metabolic, rheumatic, and cardiovascular diseases. Front Physiol 11:578966. https://doi.org/10.3389/fphys.2020.578966CrossRefPubMedPubMedCentral

Carbone F, Bonaventura A, Liberale L et al (2020) Atherosclerosis in rheumatoid arthritis: promoters and opponents. Clin Rev Allergy Immunol 58(1):1–14. https://doi.org/10.1007/s12016-018-8714-zCrossRefPubMed

Medina G, Vera-Lastra O, Peralta-Amaro AL, Jiménez-Arellano MP, Saavedra MA, Cruz-Domínguez MP et al (2018) Metabolic syndrome, autoimmunity and rheumatic diseases. Pharmacol Res 133:277–288. https://doi.org/10.1016/j.phrs.2018.01.009CrossRefPubMed

Francisco V, Ruiz-Fernández C, Pino J et al (2019) Adipokines: linking metabolic syndrome, the immune system, and arthritic diseases. Biochem Pharmacol 165:196–206. https://doi.org/10.1016/j.bcp.2019.03.030CrossRefPubMed

10.

Mok CC (2019) Metabolic syndrome and systemic lupus erythematosus: the connection. Expert Rev Clin Immunol 15(7):765–775. https://doi.org/10.1080/1744666X.2019.1620601CrossRefPubMed

11.

Mehta P, Gasparyan AY, Zimba O, Kitas GD, Yessirkepov M (2022) Interplay of diabetes mellitus and rheumatic diseases amidst the COVID-19 pandemic: influence on the risk of infection, outcomes, and immune responses. Clin Rheumatol 41(12):3897–3913. https://doi.org/10.1007/s10067-022-06365-yCrossRefPubMedPubMedCentral

12.

Huss V, Bower H, Wadström H, Frisell T, Askling J, ARTIS group (2022) Short- and longer-term cancer risks with biologic and targeted synthetic disease-modifying antirheumatic drugs as used against rheumatoid arthritis in clinical practice. Rheumatology (Oxford) 61(5):1810–1818. https://doi.org/10.1093/rheumatology/keab570CrossRefPubMed

13.

Simon TA, Boers M, Hochberg M et al (2019) Comparative risk of malignancies and infections in patients with rheumatoid arthritis initiating abatacept versus other biologics: a multi-database real-world study. Arthritis Res Ther 21(1):228. https://doi.org/10.1186/s13075-019-1992-xCrossRefPubMedPubMedCentral

14.

De Cock D, Hyrich K (2018) Malignancy and rheumatoid arthritis: epidemiology, risk factors and management. Best Pract Res Clin Rheumatol 32(6):869–886. https://doi.org/10.1016/j.berh.2019.03.011CrossRefPubMed

15.

Kedra J, Seror R (2023) Cancer screening in chronic inflammatory rheumatic diseases. Joint Bone Spine 90(4):105557. https://doi.org/10.1016/j.jbspin.2023.105557CrossRefPubMed

16.

Cappelli LC, Shah AA (2020) The relationships between cancer and autoimmune rheumatic diseases. Best Pract Res Clin Rheumatol 34(1):101472. https://doi.org/10.1016/j.berh.2019.101472CrossRefPubMedPubMedCentral

17.

Alunno A, Leone MC, Giacomelli R, Gerli R, Carubbi F (2018) Lymphoma and lymphomagenesis in primary Sjögren’s syndrome. Front Med (Lausanne) 5:102. https://doi.org/10.3389/fmed.2018.00102CrossRefPubMed

18.

Lange E, Blizzard L, Venn A, Francis H, Jones G (2016) Disease-modifying anti-rheumatic drugs and non-melanoma skin cancer in inflammatory arthritis patients: a retrospective cohort study. Rheumatology (Oxford) 55(9):1594–1600. https://doi.org/10.1093/rheumatology/kew214CrossRefPubMed

19.

Weinmann SC, Pisetsky DS (2019) Mechanisms of immune-related adverse events during the treatment of cancer with immune checkpoint inhibitors. Rheumatology (Oxford) 58(Suppl 7):vii59–vii67. https://doi.org/10.1093/rheumatology/kez308CrossRefPubMed

20.

Pedersen JK, Holst R, Primdahl J, Svendsen AJ, Hørslev-Petersen K (2018) Mortality and its predictors in patients with rheumatoid arthritis: a Danish population-based inception cohort study. Scand J Rheumatol 47(5):371–377. https://doi.org/10.1080/03009742.2017.1420223CrossRefPubMed

21.

Lee EE, Shin A, Lee J et al (2022) All-cause and cause-specific mortality of patients with rheumatoid arthritis in Korea: a nation-wide population-based study. Joint Bone Spine 89(1):105269. https://doi.org/10.1016/j.jbspin.2021.105269CrossRefPubMed

22.

Fedorchenko Y, Zimba O (2023) Long COVID in autoimmune rheumatic diseases. Rheumatol Int 43(7):1197–1207. https://doi.org/10.1007/s00296-023-05319-0CrossRefPubMedPubMedCentral

23.

Riley TR, George MD (2021) Risk for infections with glucocorticoids and DMARDs in patients with rheumatoid arthritis. RMD Open 7(1):e001235. https://doi.org/10.1136/rmdopen-2020-001235CrossRefPubMedPubMedCentral

24.

Sharma V, Sharma A (2022) Infectious mimics of rheumatoid arthritis. Best Pract Res Clin Rheumatol 36(1):101736. https://doi.org/10.1016/j.berh.2021.101736CrossRefPubMed

25.

Alves C, Penedones A, Mendes D, Marques FB (2022) The risk of infections associated with JAK inhibitors in rheumatoid arthritis: a systematic review and network meta-analysis. J Clin Rheumatol 28(2):e407–e414. https://doi.org/10.1097/RHU.0000000000001749CrossRefPubMed

26.

Bergmans BJM, Gebeyehu BY, van Puijenbroek EP et al (2023) Infections in biological and targeted synthetic drug use in rheumatoid arthritis: where do we stand? A scoping review and meta-analysis. Rheumatol Ther 10(5):1147–1165. https://doi.org/10.1007/s40744-023-00571-zCrossRefPubMedPubMedCentral

27.

Mehta B, Pedro S, Ozen G et al (2019) Serious infection risk in rheumatoid arthritis compared with non-inflammatory rheumatic and musculoskeletal diseases: a US national cohort study. RMD Open 5(1):e000935. https://doi.org/10.1136/rmdopen-2019-000935CrossRefPubMedPubMedCentral

28.

Sangha PS, Thakur M, Akhtar Z, Ramani S, Gyamfi RS (2020) The Link between rheumatoid arthritis and dementia: a review. Cureus 12(4):e7855. https://doi.org/10.7759/cureus.7855CrossRefPubMedPubMedCentral

29.

Lu MC, Livneh H, Yen CT et al (2020) Association of use of rehabilitation services with development of dementia among patients with rheumatoid arthritis: analysis of domestic data in Taiwan. Front Med (Lausanne) 7:446. https://doi.org/10.3389/fmed.2020.00446ADSCrossRefPubMed

30.

van Dijk GM, Veenhof C, Schellevis F et al (2008) Comorbidity, limitations in activities and pain in patients with osteoarthritis of the hip or knee. BMC Musculoskelet Disord 9:95. https://doi.org/10.1186/1471-2474-9-95CrossRefPubMedPubMedCentral

31.

Gasparyan AY, Ayvazyan L, Blackmore H, Kitas GD (2011) Writing a narrative biomedical review: considerations for authors, peer reviewers, and editors. Rheumatol Int 31(11):1409–1417. https://doi.org/10.1007/s00296-011-1999-3CrossRefPubMed

32.

Uhlig T, Bjørneboe O, Krøll F, Palm Ø, Olsen IC, Grotle M (2016) Involvement of the multidisciplinary team and outcomes in inpatient rehabilitation among patients with inflammatory rheumatic disease. BMC Musculoskelet Disord 17:18. https://doi.org/10.1186/s12891-016-0870-9CrossRefPubMedPubMedCentral

33.

Karakasis P, Patoulias D, Stachteas P, Lefkou E, Dimitroulas T, Fragakis N (2023) Accelerated atherosclerosis and management of cardiovascular risk in autoimmune rheumatic diseases: an updated review. Curr Probl Cardiol 48(12):101999. https://doi.org/10.1016/j.cpcardiol.2023.101999CrossRefPubMed

34.

Eder L, Harvey P (2022) Cardio-rheumatology: it’s time to collaborate. Nat Rev Rheumatol 18(5):247–248. https://doi.org/10.1038/s41584-022-00774-8CrossRefPubMed

35.

Piotrowicz R, Wolszakiewicz J (2008) Cardiac rehabilitation following myocardial infarction. Cardiol J 15(5):481–487PubMed

36.

Wang R, Duan G, Xu H et al (2022) Analysis on the effect of the rehabilitation intervention-centered targeted nursing model on the cardiac function recovery and negative emotions in patients with acute myocardial infarction. J Healthc Eng 2022:1246092. https://doi.org/10.1155/2022/1246092CrossRefPubMedPubMedCentral

37.

Bush M, Kucharska-Newton A, Simpson RJ Jr, Fang G, Stürmer T, Brookhart MA (2020) Effect of initiating cardiac rehabilitation after myocardial infarction on subsequent hospitalization in older adults. J Cardiopulm Rehabil Prev 40(2):87–93. https://doi.org/10.1097/HCR.0000000000000452CrossRefPubMedPubMedCentral

38.

Palomäki A, Kerola AM, Malmberg M, Rautava P, Kyto V (2021) Patients with rheumatoid arthritis have impaired long-term outcomes after myocardial infarction: a nationwide case-control registry study. Rheumatology (Oxford) 60(11):5205–5215. https://doi.org/10.1093/rheumatology/keab204CrossRefPubMed

39.

McCoy SS, Crowson CS, Maradit-Kremers H et al (2013) Longterm outcomes and treatment after myocardial infarction in patients with rheumatoid arthritis. J Rheumatol 40(5):605–610. https://doi.org/10.3899/jrheum.120941CrossRefPubMedPubMedCentral

40.

Frølund JC, Primdahl J (2015) Patients’ experiences of nurse-led screening for cardiovascular risk in rheumatoid arthritis. Musculoskeletal Care 13(4):236–247. https://doi.org/10.1002/msc.1104CrossRefPubMed

41.

Primdahl J, Ferreira RJ, Garcia-Diaz S, Ndosi M, Palmer D, van Eijk-Hustings Y (2016) Nurses’ role in cardiovascular risk assessment and management in people with inflammatory arthritis: a European perspective. Musculoskeletal Care 14(3):133–151. https://doi.org/10.1002/msc.1121CrossRefPubMed

42.

McLachlan A, Kerr A, Lee M, Dalbeth N (2011) Nurse-led cardiovascular disease risk management intervention for patients with gout. Eur J Cardiovasc Nurs 10(2):94–100. https://doi.org/10.1016/j.ejcnurse.2010.05.001CrossRefPubMed

43.

Dougados M, Soubrier M, Perrodeau E et al (2015) Impact of a nurse-led programme on comorbidity management and impact of a patient self-assessment of disease activity on the management of rheumatoid arthritis: results of a prospective, multicentre, randomised, controlled trial (COMEDRA). Ann Rheum Dis 74(9):1725–1733. https://doi.org/10.1136/annrheumdis-2013-204733CrossRefPubMed

44.

Zhang J, Zheng X, Ma D, Liu C, Ding Y (2022) Nurse-led care versus usual care on cardiovascular risk factors for patients with type 2 diabetes: a systematic review and meta-analysis. BMJ Open 12(3):e058533. https://doi.org/10.1136/bmjopen-2021-058533CrossRefPubMedPubMedCentral

45.

Gossec L, Soubrier M, Foissac F et al (2019) Screening for and management of comorbidities after a nurse-led program: results of a 3-year longitudinal study in 769 established rheumatoid arthritis patients. RMD Open 5(2):e000914. https://doi.org/10.1136/rmdopen-2019-000914CrossRefPubMedPubMedCentral

46.

Arjunan P, Trichur RV (2020) The impact of nurse-led cardiac rehabilitation on quality of life and biophysiological parameters in patients with heart failure: a randomized clinical trial. J Nurs Res 29(1):e130. https://doi.org/10.1097/JNR.0000000000000407CrossRefPubMedPubMedCentral

47.

Küçükdeveci AA, Oral A, Ilıeva EM, Varela E, Valero R, Berteanu M et al (2013) Inflammatory arthritis. The role of physical and rehabilitation medicine physicians. The European perspective based on the best evidence. A paper by the UEMS-PRM section professional practice committee. Eur J Phys Rehabil Med 49(4):551–556PubMed

48.

Chehade L, Jaafar ZA, El Masri D et al (2019) Lifestyle modification in rheumatoid arthritis: dietary and physical activity recommendations based on evidence. Curr Rheumatol Rev 15(3):209–214CrossRefPubMed

49.

Shao JH, Yu KH, Chen SH (2021) Effectiveness of a self-management program for joint protection and physical activity in patients with rheumatoid arthritis: a randomized controlled trial. Int J Nurs Stud 116:103752CrossRefPubMed

50.

García-Rodríguez F, Arana-Guajardo AC, Villarreal-Treviño AV et al (2023) Design of a rheumatology transition clinic for a resource-constrained setting. Indian J Pediatr 90(1):29–37CrossRefPubMed

51.

Elera-Fitzcarrald C, Huarcaya-Victoria J, Alarcón GS, Ugarte-Gil MF (2021) Rheumatology and psychiatry: allies in times of COVID-19. Clin Rheumatol 40(8):3363–3367CrossRefPubMedPubMedCentral

52.

Roll SC, Hardison ME (2017) Effectiveness of occupational therapy interventions for adults with musculoskeletal conditions of the forearm, wrist, and hand: a systematic review. Am J Occup Ther 71(1):7101180010p1-7101180010p12. https://doi.org/10.5014/ajot.2017.023234CrossRefPubMed

53.

Siegel P, Tencza M, Apodaca B, Poole JL (2017) Effectiveness of occupational therapy interventions for adults with rheumatoid arthritis: a systematic review. Am J Occup Ther 71(1):7101180050p1-7101180050p11. https://doi.org/10.5014/ajot.2017.023176CrossRefPubMed

54.

Gavin JP, Rossiter L, Fenerty V et al (2023) The role of occupational therapy for the self-management of rheumatoid arthritis: a protocol for a mixed methods systematic review. Musculoskeletal Care 21(1):56–62. https://doi.org/10.1002/msc.1665CrossRefPubMed

55.

Kvien TK, Balsa A, Betteridge N et al (2020) Considerations for improving quality of care of patients with rheumatoid arthritis and associated comorbidities. RMD Open 6(2):e001211. https://doi.org/10.1136/rmdopen-2020-001211CrossRefPubMedPubMedCentral

56.

Marion CE, Balfe LM (2011) Potential advantages of interprofessional care in rheumatoid arthritis. J Manag Care Pharm 17(9 Suppl B):S25–S29. https://doi.org/10.18553/jmcp.2011.17.s9-b.S25CrossRefPubMed

57.

Engelberg-Cook E, Hu D, Kurklinsky S et al (2021) Outcomes of a comprehensive pain rehabilitation program for patients with fibromyalgia. Mayo Clin Proc Innov Qual Outcomes 5(6):1056–1065. https://doi.org/10.1016/j.mayocpiqo.2021.08.008CrossRefPubMedPubMedCentral

58.

Bearne LM, Byrne AM, Segrave H, White CM (2016) Multidisciplinary team care for people with rheumatoid arthritis: a systematic review and meta-analysis. Rheumatol Int 36(3):311–324. https://doi.org/10.1007/s00296-015-3380-4CrossRefPubMed

59.

Hall J, Julia Kaal K, Lee J, Duncan R, Tsao N, Harrison M (2018) Patient satisfaction and costs of multidisciplinary models of care in rheumatology: a review of the recent literature. Curr Rheumatol Rep 20(4):19. https://doi.org/10.1007/s11926-018-0727-3CrossRefPubMed

60.

Żuk B, Maślińska M (2017) The importance of physiotherapy in the sexuality of patients with rheumatic diseases. Reumatologia 55(5):237–241. https://doi.org/10.5114/reum.2017.71640CrossRefPubMedPubMedCentral

61.

Favalli EG, Biggioggero M, Crotti C, Becciolini A, Raimondo MG, Meroni PL (2019) Sex and management of rheumatoid arthritis. Clin Rev Allergy Immunol 56(3):333–345. https://doi.org/10.1007/s12016-018-8672-5CrossRefPubMed

62.

Romera Baures M, Seoane-Mato D, Alegre-Sancho JJ et al (2022) Impact of rheumatoid arthritis on sexuality: adaptation and validation of the qualisex questionnaire for use in Spain. Rheumatol Int 42(10):1819–1829. https://doi.org/10.1007/s00296-021-05043-7CrossRefPubMed

63.

Zhao S, Li E, Wang J, Luo L, Luo J, Zhao Z (2018) Rheumatoid arthritis and risk of sexual dysfunction: a systematic review and metaanalysis. J Rheumatol 45(10):1375–1382. https://doi.org/10.3899/jrheum.170956CrossRefPubMed

64.

Baniotopoulos P, Pyrgidis N, Minopoulou I et al (2022) Treatment of sexual dysfunction in women with systemic autoimmune rheumatic disorders: a systematic review. Sex Med Rev 10(4):520–528. https://doi.org/10.1016/j.sxmr.2022.08.002CrossRefPubMed

65.

Orellana C, Gratacós J, Galisteo C, Larrosa M (2009) Sexual dysfunction in patients with fibromyalgia. Curr Rheumatol Rep 11(6):437–442. https://doi.org/10.1007/s11926-009-0064-7CrossRefPubMed

66.

Perez-Garcia LF, Röder E, Pastoor H, Bolt JM, van Exel J, Dolhain RJEM (2021) It is not just about sex: viewpoints of men with inflammatory arthritis on the overall impact of the disease on their sexual health. RMD Open 7(3):e001821. https://doi.org/10.1136/rmdopen-2021-001821CrossRefPubMedPubMedCentral

67.

Napolitano L, Pantano I, Romano L et al (2023) Sexual dysfunctions of rheumatological patients are a neglected issue: results from a national survey of Italian Society of Rheumatology. Arch Ital Urol Androl 95(2):11337. https://doi.org/10.4081/aiua.2023.11337CrossRefPubMed

68.

Cornelissen LE, van der Mark EJ, Pennings P et al (2021) What matters to patients with rheumatoid arthritis when facing medical or non-medical treatment decisions? Patient Prefer Adherence 15:1827–1841. https://doi.org/10.2147/PPA.S322257CrossRefPubMedPubMedCentral

69.

Bay LT, Graugaard C, Nielsen DS, Möller S, Ellingsen T, Giraldi A (2020) sexual health and dysfunction in patients with rheumatoid arthritis: a cross-sectional single-center study. Sex Med 8(4):615–630. https://doi.org/10.1016/j.esxm.2020.07.004CrossRefPubMedPubMedCentral

70.

Abda E, Selim Z, Teleb S, Zaghira M, Fawzy M, Hamed S (2016) Sexual function in females with rheumatoid arthritis: relationship with physical and psychosocial states. Arch Rheumatol 31(3):239–247. https://doi.org/10.5606/ArchRheumatol.2016.5838CrossRefPubMedPubMedCentral

71.

Metsios GS, Moe RH, van der Esch M et al (2020) The effects of exercise on cardiovascular disease risk factors and cardiovascular physiology in rheumatoid arthritis. Rheumatol Int 40(3):347–357. https://doi.org/10.1007/s00296-019-04483-6CrossRefPubMed

72.

Drosos GC, Vedder D, Houben E et al (2022) EULAR recommendations for cardiovascular risk management in rheumatic and musculoskeletal diseases, including systemic lupus erythematosus and antiphospholipid syndrome. Ann Rheum Dis 81(6):768–779. https://doi.org/10.1136/annrheumdis-2021-221733CrossRefPubMed

73.

Thoma LM, Wellsandt E, Wipfler K, Michaud K (2023) Examining rehabilitation dose in adults with rheumatoid arthritis: association with baseline factors and change in clinical outcomes. Arthritis Care Res (Hoboken) 75(6):1261–1268. https://doi.org/10.1002/acr.25019CrossRefPubMed

74.

Radu AF, Bungau SG (2021) Management of rheumatoid arthritis: an overview. Cells 10(11):2857. https://doi.org/10.3390/cells10112857CrossRefPubMedPubMedCentral

75.

Sobejana M, van den Hoek J, Metsios GS, Kitas GD, van der Leeden M, Verberne S et al (2022) Exercise intervention on cardiorespiratory fitness in rheumatoid arthritis patients with high cardiovascular disease risk: a single-arm pilot study. Clin Rheumatol 41(12):3725–3734. https://doi.org/10.1007/s10067-022-06343-4CrossRefPubMed

76.

Peçanha T, Bannell DJ, Sieczkowska SM et al (2021) Effects of physical activity on vascular function in autoimmune rheumatic diseases: a systematic review and meta-analysis. Rheumatology (Oxford) 60(7):3107–3120. https://doi.org/10.1093/rheumatology/keab094CrossRefPubMed

77.

Stavropoulos-Kalinoglou A, Metsios GS, Veldhuijzen van Zanten JJ, Nightingale P, Kitas GD et al (2013) Individualised aerobic and resistance exercise training improves cardiorespiratory fitness and reduces cardiovascular risk in patients with rheumatoid arthritis. Ann Rheum Dis 72(11):1819–1825. https://doi.org/10.1136/annrheumdis-2012-202075CrossRefPubMed

78.

Cooney JK, Ahmad YA, Moore JP, Sandoo A, Thom JM (2019) The impact of cardiorespiratory fitness on classical cardiovascular disease risk factors in rheumatoid arthritis: a cross-sectional and longitudinal study. Rheumatol Int 39(10):1759–1766. https://doi.org/10.1007/s00296-019-04431-4CrossRefPubMed

79.

Nordén KR, Semb AG, Dagfinrud H et al (2023) Associations between cardiovascular risk factors, disease activity and cardiorespiratory fitness in patients with inflammatory joint disease: a cross-sectional analysis. BMC Sports Sci Med Rehabil 15(1):63. https://doi.org/10.1186/s13102-023-00678-4CrossRefPubMedPubMedCentral

80.

Liff MH, Hoff M, Wisloff U, Videm V (2021) Reduced cardiorespiratory fitness is a mediator of excess all-cause mortality in rheumatoid arthritis: the Trøndelag health study. RMD Open 7(1):e00154. https://doi.org/10.1136/rmdopen-2020-001545CrossRef

81.

Peynirci Cerşit H, Yağcı İ, Cerşit S (2019) The improvement in aerobic capacity, disease activity, and function in patients with rheumatoid arthritis following cardiac rehabilitation program: a single-center, controlled study. Turk J Phys Med Rehabil 66(2):121–133. https://doi.org/10.5606/tftrd.2020.3250CrossRefPubMedPubMedCentral

82.

Küçükdeveci AA (2019) Nonpharmacological treatment in established rheumatoid arthritis. Best Pract Res Clin Rheumatol 33(5):101482. https://doi.org/10.1016/j.berh.2019.101482CrossRefPubMed

83.

Rosa-Gonçalves D, Bernardes M, Costa L (2018) Quality of life and functional capacity in patients with rheumatoid arthritis - cross-sectional study. Reumatol Clin (Engl Ed) 14(6):360–366. https://doi.org/10.1016/j.reuma.2017.03.002CrossRefPubMed

84.

Dadgostar H, Firouzinezhad S, Ansari M, Younespour S, Mahmoudpour A, Khamseh ME (2016) Supervised group-exercise therapy versus home-based exercise therapy: their effects on quality of life and cardiovascular risk factors in women with type 2 diabetes. Diabetes Metab Syndr 10(2 Suppl 1):S30–S36. https://doi.org/10.1016/j.dsx.2016.01.016CrossRefPubMed

85.

Pan B, Ge L, Xun YQ, Chen YJ, Gao CY, Han X et al (2018) Exercise training modalities in patients with type 2 diabetes mellitus: a systematic review and network meta-analysis. Int J Behav Nutr Phys Act 15(1):72. https://doi.org/10.1186/s12966-018-0703-3CrossRefPubMedPubMedCentral

86.

Hagel S, Lindqvist E, Petersson IF et al (2014) Which patients improve the most after arthritis rehabilitation? A study of predictors in patients with inflammatory arthritis in Northern Europe, the STAR-ETIC collaboration. J Rehabil Med 46(3):250–257. https://doi.org/10.2340/16501977-1267CrossRefPubMed

87.

Grønhaug G, Hagfors J, Borch I, Østerås N, Hagen KB (2015) Perceived quality of health care services among people with osteoarthritis - results from a nationwide survey. Patient Prefer Adherence 9:1255–1261. https://doi.org/10.2147/PPA.S82441CrossRefPubMedPubMedCentral

88.

Kremsreiter K, Henrich G, Book K, Herschbach P, Marten-Mittag B, Dinkel A (2013) Einfluss stationärer Rehabilitationsleistungen auf die langfristige gesundheitsbezogene Lebensqualität von Patienten mit Krebs und rheumatoider Arthritis: eine KTL-Daten-Analyse [Effects of inpatient rehabilitation on long-term health-related quality of life in patients with cancer and rheumatoid arthritis: an analysis based on the classification of therapeutic procedures codes (KTL)]. Gesundheitswesen 75(5):317–320. https://doi.org/10.1055/s-0032-1321746CrossRefPubMed

89.

Pundole X, Suarez-Almazor ME (2020) Cancer and rheumatoid arthritis. Rheum Dis Clin North Am 46(3):445–462. https://doi.org/10.1016/j.rdc.2020.05.003CrossRefPubMed

90.

Kudre D, Chen Z, Richard A et al (2020) multidisciplinary outpatient cancer rehabilitation can improve cancer patients’ physical and psychosocial status-a systematic review. Curr Oncol Rep 22(12):122. https://doi.org/10.1007/s11912-020-00979-8CrossRefPubMedPubMedCentral

91.

Raj VS, Pugh TM, Yaguda SI, Mitchell CH, Mullan SS, Garces NS (2020) The who, what, why, when, where, and how of team-based interdisciplinary cancer rehabilitation. Semin Oncol Nurs 36(1):150974. https://doi.org/10.1016/j.soncn.2019.150974CrossRefPubMed

92.

Zheng JY, Mixon AC, McLarney MD (2021) Safety, precautions, and modalities in cancer rehabilitation: an updated review. Curr Phys Med Rehabil Rep 9(3):142–153. https://doi.org/10.1007/s40141-021-00312-9CrossRefPubMedPubMedCentral

93.

Haq IU, Chhatwal K, Sanaka K, Xu B (2022) Artificial intelligence in cardiovascular medicine: current insights and future prospects. Vasc Health Risk Manag 18:517–528. https://doi.org/10.2147/VHRM.S279337CrossRefPubMedPubMedCentral

94.

Nagatomi Y, Ide T, Higuchi T, Nezu T, Fujino T, Tohyama T et al (2022) Home-based cardiac rehabilitation using information and communication technology for heart failure patients with frailty. ESC Heart Fail 9(4):2407–2418. https://doi.org/10.1002/ehf2.13934CrossRefPubMedPubMedCentral

95.

Li C, Huang J, Wu H et al (2023) Management of rheumatoid arthritis with a digital health application: a multicenter, pragmatic randomized clinical trial. JAMA Netw Open 6(4):e238343. https://doi.org/10.1001/jamanetworkopen.2023.8343CrossRefPubMedPubMedCentral

96.

Zangger G, Bricca A, Liaghat B et al (2023) Benefits and harms of digital health interventions promoting physical activity in people with chronic conditions: systematic review and meta-analysis. J Med Internet Res 25:e46439. https://doi.org/10.2196/46439CrossRefPubMedPubMedCentral

97.

Perrotta FM, Scriffignano S, Benfaremo D, Ronga M, Luchetti MM, Lubrano E (2021) New insights in physical therapy and rehabilitation in psoriatic arthritis: a review. Rheumatol Ther 8(2):639–649. https://doi.org/10.1007/s40744-021-00298-9CrossRefPubMedPubMedCentral

98.

Assumpção A, Matsutani LA, Yuan SL, Santo AS, Sauer J, Mango P et al (2018) Muscle stretching exercises and resistance training in fibromyalgia: which is better? A three-arm randomized controlled trial. Eur J Phys Rehabil Med 54(5):663–670. https://doi.org/10.23736/S1973-9087.17.04876-6CrossRefPubMed

99.

Estévez-López F, Maestre-Cascales C, Russell D, Álvarez-Gallardo IC, Rodriguez-Ayllon M, Hughes CM et al (2021) Effectiveness of exercise on fatigue and sleep quality in fibromyalgia: a systematic review and meta-analysis of randomized trials. Arch Phys Med Rehabil 102(4):752–761. https://doi.org/10.1016/j.apmr.2020.06.019CrossRefPubMed

100.

Bravo C, Skjaerven LH, Guitard Sein-Echaluce L, Catalan-Matamoros D (2019) Effectiveness of movement and body awareness therapies in patients with fibromyalgia: a systematic review and meta-analysis. Eur J Phys Rehabil Med 55(5):646–657. https://doi.org/10.23736/S1973-9087.19.05291-2CrossRefPubMed

101.

Zhang Y, Wang C (2020) Acupuncture and chronic musculoskeletal pain. Curr Rheumatol Rep 22(11):80. https://doi.org/10.1007/s11926-020-00954-zCrossRefPubMedPubMedCentral

102.

Karagülle M, Kardeş S, Karagülle MZ (2017) Real-life effectiveness of spa therapy in rheumatic and musculoskeletal diseases: a retrospective study of 819 patients. Int J Biometeorol 61(11):1945–1956. https://doi.org/10.1007/s00484-017-1384-3CrossRefPubMed

103.

Maindet C, Maire A, Vermorel C, Cracowski C, Rolland C, Forestier R et al (2021) Spa therapy for the treatment of fibromyalgia: an open, randomized multicenter trial. J Pain 22(8):940–951. https://doi.org/10.1016/j.jpain.2021.02.010CrossRefPubMed

104.

Johansen I, Klokkerud M, Anke A, Børke JB, Glott T, Hauglie U et al (2019) A quality indicator set for use in rehabilitation team care of people with rheumatic and musculoskeletal diseases; development and pilot testing. BMC Health Serv Res 19(1):265. https://doi.org/10.1186/s12913-019-4091-4CrossRefPubMedPubMedCentral

105.

Sand-Svartrud AL, Berdal G, Azimi M, Bø I, Dager TN, Eppeland SG et al (2021) A quality indicator set for rehabilitation services for people with rheumatic and musculoskeletal diseases demonstrates adequate responsiveness in a pre-post evaluation. BMC Health Serv Res 21(1):164. https://doi.org/10.1186/s12913-021-06164-2CrossRefPubMedPubMedCentral

106.

Rodère M, Pereira B, Soubrier M, Fayet F, Piperno M, Pallot-Prades B et al (2022) Development and validation of a self-administered questionnaire measuring essential knowledge in patients with rheumatoid arthritis. Rheumatol Int 42(10):1785–1795. https://doi.org/10.1007/s00296-022-05090-8CrossRefPubMedPubMedCentral

107.

Beauvais C, Pereira B, Pham T, Sordet C, Claudepierre P, Fayet F et al (2023) Development and validation of a self-administered questionnaire measuring essential knowledge in patients with axial spondyloarthritis. J Rheumatol 50(1):56–65. https://doi.org/10.3899/jrheum.211314CrossRefPubMed

108.

Beauvais C, Rodère M, Pereira B, Legoupil N, Piperno M, Pallot Prades B et al (2019) Essential knowledge for patients with rheumatoid arthritis or spondyloarthritis: results of a multicentric survey in France among health professionals and patients. Joint Bone Spine 86(6):747–752. https://doi.org/10.1016/j.jbspin.2019.06.006CrossRefPubMed

109.

Ma S, Zhang L, Man S, Bian T, Li H, Li W et al (2022) Patient-reported adherence to physical exercises of patients with ankylosing spondylitis. Clin Rheumatol 41(8):2423–2429. https://doi.org/10.1007/s10067-022-06189-wCrossRefPubMedPubMedCentral

110.

Feddersen H, Søndergaard J, Andersen L, Munksgaard B, Primdahl J (2022) Barriers and facilitators for coherent rehabilitation among people with inflammatory arthritis - a qualitative interview study. BMC Health Serv Res 22(1):1347. https://doi.org/10.1186/s12913-022-08773-xCrossRefPubMedPubMedCentral

111.

Ben Tekaya A, Hannech E, Saidane O, Rouached L, Bouden S, Tekaya R et al (2022) Association between rheumatic disease comorbidity index and factors of poor prognosis in a cohort of 280 patients with rheumatoid arthritis. BMC Rheumatol 6(1):78. https://doi.org/10.1186/s41927-022-00308-5CrossRefPubMedPubMedCentral

112.

Krist AH, Tong ST, Aycock RA, Longo DR (2017) Engaging patients in decision-making and behavior change to promote prevention. Stud Health Technol Inform 240:284–302PubMedPubMedCentral

Title: Rehabilitation of patients with inflammatory rheumatic diseases and comorbidities: unmet needs
Authors: Yuliya Fedorchenko
Khaiyom Mahmudov
Zhumabek Abenov
Olena Zimba
Marlen Yessirkepov
Publication date: 31-01-2024
Publisher: Springer Berlin Heidelberg
Keywords: Inflammatory Rheumatic Diseases
Rheumatoid Arthritis
Fibromyalgia
Fibromyalgia
Psoriatic Arthritis
Systemic Lupus Erythematosus
Published in: Rheumatology International / Issue 4/2024
Print ISSN: 0172-8172
Electronic ISSN: 1437-160X
DOI: https://doi.org/10.1007/s00296-023-05529-6

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