Skip to main content
Top
Published in: European Spine Journal 11/2023

Open Access 14-09-2023 | Gout | Review Article

Patient characteristics, surgical treatment, and outcomes in spinal gout: a systematic review of 315 cases

Authors: Netanja I. Harlianto, Zaneta N. Harlianto

Published in: European Spine Journal | Issue 11/2023

Login to get access

Abstract

Purpose

To systematically investigate all published literature on spinal gout regarding location demographics, patient characteristics, treatment, and outcomes.

Methods

We performed a systematic literature search of Medline and EMBASE from inception until April 15, 2023. Two investigators performed data extraction and quality assessment of location demographics and patient characteristics and outcomes of all article types describing spinal gout.

Results

A total of 214 articles (204 case reports and 10 case series) were included, encompassing 315 subjects with spinal gout (81% male, mean age 58.1 years; range: 16–92). Most cases (36%) were between the age of 60–69 years. We observed an increase in publications and cases from 1950 to the present. Most patients were from institutions in Asia (n = 119, 37.8%) and North America (n = 96, 30.5%). Reported symptoms frequently included back pain (75%), radiating pain to extremities (27.3%), and weakness in the extremities (26.3%). The lumbar spine was most often affected. Pharmacological treatment was described for 108 (34.2%) patients. Surgery was performed for 146 (46.3%) of patients, of which 4.8% had postoperative complications. Three patients (2%) required secondary surgery for recurrence.

Conclusion

Published cases of spinal gout have increased over the last decades. Patient characteristics of spinal gout were similar to findings in systemic gout. Trends identified in patient characteristics and treatment outcomes may help guide patient management and improve our understanding of spinal gout.
Appendix
Available only for authorised users
Literature
11.
go back to reference Hou LC, Hsu AR, Veeravagu A, Boakye M (2007) Spinal gout in a renal transplant patient: a case report and literature review. Surg Neurol 67:65–73CrossRefPubMed Hou LC, Hsu AR, Veeravagu A, Boakye M (2007) Spinal gout in a renal transplant patient: a case report and literature review. Surg Neurol 67:65–73CrossRefPubMed
14.
go back to reference Liberati A, Altman DG, Tetzlaff J, Mulrow C, Gøtzsche PC, Ioannidis JP et al (2009) The PRISMA statement for reporting systematic reviews and meta-analyses of studies that evaluate healthcare interventions: explanation and elaboration. BMJ 339:b2700CrossRefPubMedPubMedCentral Liberati A, Altman DG, Tetzlaff J, Mulrow C, Gøtzsche PC, Ioannidis JP et al (2009) The PRISMA statement for reporting systematic reviews and meta-analyses of studies that evaluate healthcare interventions: explanation and elaboration. BMJ 339:b2700CrossRefPubMedPubMedCentral
Metadata
Title
Patient characteristics, surgical treatment, and outcomes in spinal gout: a systematic review of 315 cases
Authors
Netanja I. Harlianto
Zaneta N. Harlianto
Publication date
14-09-2023
Publisher
Springer Berlin Heidelberg
Keyword
Gout
Published in
European Spine Journal / Issue 11/2023
Print ISSN: 0940-6719
Electronic ISSN: 1432-0932
DOI
https://doi.org/10.1007/s00586-023-07942-8

Other articles of this Issue 11/2023

European Spine Journal 11/2023 Go to the issue