Skip to main content
Key Specialties
Cardiology Diabetology Endocrinology Gastroenterology Geriatrics and Gerontology Gynecology and Obstetrics Hematology Infectious Disease Internal Medicine Nephrology Neurology Oncology Pediatrics Respiratory Medicine Rheumatology Surgery
Congress Coverage
2024 ACC Congress 2023 ESMO Congress 2023 EASD Congress 2023 ERS Congress 2023 ESC Congress
Clinical Collections
Advances in Alzheimer’s

Keynote webinar | Spotlight on medication adherence

LIVE: Thursday 27th June 2024, 18:00-19:30 (CEST)
Join our expert panel to discover why you need to understand the drivers of non-adherence in your patients, and how you can optimize medication adherence in your clinics to drastically improve patient outcomes.
ADVANCED SEARCH
Log in
Top
Archives of Virology
Published in: Archives of Virology 10/2019

01-10-2019 | Leukemia | Brief Report

Molecular detection and characterization of genotype 1 bovine leukemia virus from beef cattle in the traditional sector in Zambia

Authors: Mundia M. Phiri, Evans Kaimoyo, Katendi Changula, Isaac Silwamba, Herman M. Chambaro, Penjaninge Kapila, Masahiro Kajihara, Martin Simuunza, John Bwalya Muma, Girja S. Pandey, Ayato Takada, Aaron S. Mweene, Simbarashe Chitanga, Edgar Simulundu

Published in: Archives of Virology | Issue 10/2019

Login to get access

Abstract

Whilst bovine leukemia virus (BLV) causes considerable economic losses to the dairy industry worldwide, information on its molecular epidemiology and economic impact in beef cattle is limited. Here, blood from 880 animals from Zambia’s major cattle-rearing provinces was screened for BLV by nested PCR. Positive pools were sequenced and phylogenetically analyzed. The estimated pooled prevalence was 2.1%. All strains belonged to genotype 1 and formed a distinct phylogenetic cluster. The study suggests circulation of genotype 1 BLV in beef cattle in these regions. This is the first report on molecular detection and characterization of BLV from beef cattle in Africa.
Literature
1.
Ooshiro M, Konnai S, Katagiri Y, Afuso M, Arakaki N, Tsuha O, Murata S, Ohashi K (2013) Horizontal transmission of bovine leukemia virus from lymphocytotic cattle, and beneficial effects of insect vector control. Vet Rec 173:527CrossRefPubMed
2.
Juliarena MA, Barrios NC, Lützelschwab MC, Esteban EN, Gutiérrez SE (2017) Bovine leukemia virus: current perspectives. Virus Adapt Treat 2017:13–26CrossRef
3.
4.
EFSA Panel on Animal Health and Welfare (AHAW) (2015) Enzootic bovine leukosis. EFSA J 13:4188
5.
Bauermann FV, Ridpath JF, Dargatz DA (2017) Bovine leukemia virus seroprevalence among cattle presented for slaughter in the United States. J Vet Diagn Investig 29:704–706CrossRef
6.
Bartlett PC, Sordillo LM, Byrem TM, Norby B, Grooms DL, Swenson CL, Zalucha J, Erskine EJ (2014) Options for the control of bovine leukemia virus in dairy cattle. J Am Vet Med Assoc 244:914–922CrossRefPubMed
7.
Matsumura K, Inoue E, Osawa Y, Okazaki K (2011) Molecular epidemiology of bovine leukemia virus associated with enzootic bovine leukosis in Japan. Virus Res 155:343–348CrossRefPubMed
8.
Polat M, Takeshima SN, Hosomichi K, Kim J, Miyasaka T, Yamada K, Arainga M, Murakami T, Matsumoto Y, de la Barra DV, Panei CJ, Gonzalez ET, Kanemaki M, Onuma M, Giovambattista G, Aida Y (2016) A new genotype of bovine leukemia virus in South America identified by NGS-based whole genome sequencing and molecular evolutionary genetic analysis. Retrovirology 13:4CrossRefPubMedPubMedCentral
9.
Polat M, Moe HH, Shimogiri T, Moe KK, Takeshima S, Aida Y (2017) The molecular epidemiological study of bovine leukemia virus infection in Myanmar cattle. Arch Virol 162:425–437CrossRefPubMed
10.
Pandey GS, Simulundu E, Mwiinga D, Samui KL, Mweene AS, Kajihara M, Mangani A, Mwenda R, Ndebe J, Konnai S, Takada A (2017) Clinical and subclinical bovine leukemia virus infection in a dairy cattle herd in Zambia. Arch Virol 162:1051–1056CrossRefPubMed
11.
Walrand F, Fumoux F, Roelants G, Parodi AL, Levy D (1986) Incidence of bovine leukemia virus specific antibodies in West African cattle. Int J Cancer 37:619–621CrossRefPubMed
12.
Mushi EZ, Wibberley G, Kupe DC (1990) Antibodies to bovine leukemia virus in Botswana. Trop Anim Health Prod 22:126CrossRefPubMed
13.
Kaura HT, Hübschle OJ (1994) The occurrence of enzootic bovine leukosis (EBL) in Namibia—an epidemiological study. Deutsche Tierarztliche Wochenschrift 101:66–67PubMed
14.
Heinonen M, Assefa W (1995) Some observations on bovine leukosis virus antibodies in Ethiopia. Trop Anim Health Prod 27:225–226CrossRefPubMed
15.
Schoepf KC, Kapaga AM, Msami HM, Hyera JM (1997) Serological evidence of the occurrence of enzootic bovine leukosis (EBL) virus infection in cattle in Tanzania. Trop Anim Health Prod 29:15–19CrossRefPubMed
16.
Meas S, Nakayama M, Usui T, Nakazato Y, Yasuda J, Ohashi K, Onuma M (2004) Evidence for bovine immunodeficiency virus infection in cattle in Zambia. Jpn J Vet Res 52:3–8PubMed
17.
Ndou RV, Sejesho F, Dzoma BM, Motsei LE, Nyirenda M, Bakunzi FR (2011) A serosurvey of the prevalence of enzootic bovine leukosis in the Mafikeng area of the North West Province of South Africa. J Hum Ecol 36:53–55CrossRef
18.
Zaghawa A, Beier D, Abd El-Rahim IH, Karim I, El-ballal S, Conraths FJ, Marquardt O (2002) An outbreak of enzootic bovine leukosis in upper Egypt: clinical, laboratory and molecular-epidemiological studies. J Vet Med B Infect Dis Vet Public Health 49:123–129CrossRefPubMed
19.
Fechner H, Blankenstein P, Looman AC, Elwert J, Geue L, Albrecht C, Kurg A, Beier D, Marquardt O, Ebner D (1997) Provirus variants of the bovine leukemia virus and their relation to the serological status of naturally infected cattle. Virology 237:261–269CrossRefPubMed
20.
Cowling DW, Gardner IA, Johnson WO (1999) Comparison of methods for estimation of individual-level prevalence based on pooled samples. Prev Vet Med 39:211–225CrossRefPubMed
21.
Simulundu E, Chambaro HM, Sinkala Y, Kajihara M, Ogawa H, Mori A, Ndebe J, Dautu G, Mataa L, Lubaba CH, Simuntala C, Fandamu P, Simuunza M, Pandey GS, Samui KL, Misinzo G, Takada A, Mweene AS (2018) Co-circulation of multiple genotypes of African swine fever viruses among domestic pigs in Zambia (2013–2015). Transbound Emerg Dis 65:114–122CrossRefPubMed
22.
Kimura M (1980) A simple method for estimating evolutionary rate of base substitutions through comparative studies of nucleotide sequences. J Mol Evol 16:111–120CrossRefPubMed
23.
Tamura K, Stecher G, Peterson D, Filipski A, Kumar S (2013) MEGA6: molecular evolutionary genetics analysis (MEGA) software version 6.0. Mol Biol Evol 30:2725–2729CrossRefPubMedPubMedCentral
24.
Hall TA (1999) BioEdit: a user friendly biological sequences alignment editor and analysis program for Window 95/98/NT. Nucleic Acids Symp Ser 41:95–98
25.
Murakami H, Uchiyama J, Suzuki C, Nikaido S, Sato RS, Maeda Y, Tomioka M, TakeshimaS Kato H, Sakaguchi M, Sentsui H, Aida Y, Tsukamoto K (2018) Variations in the viral genome and biological properties of bovine leukemia virus wild-type strains. Virus Res 253:103–111CrossRefPubMed
26.
Lee E, Kim EJ, Ratthanophart J, Vitoonpong R, Kim BH, Cho IS, Song JY, Lee KK, Shin YK (2016) Molecular epidemiological and serological studies of bovine leukemia virus in cattle in Thailand. Infect Genet Evol 41:245–254CrossRefPubMed
27.
Mumba C, Häsler B, Muma JB, Munyeme M, Chilolo SD, Skjerve E, Rich MK (2018) Practices of traditional beef farmers in their production and marketing of cattle in Zambia. Trop Anim Health Prod 50:49–62CrossRefPubMed
28.
Moratorio G, Obal G, Dubra A, Correa A, Bianchi S, Buschiazzo A, Cristina J, Pritsch O (2010) Phylogenetic analysis of bovine leukemia viruses isolated in South America reveals diversification in seven distinct genotypes. Arch Virol 155:481–489CrossRefPubMed
29.
Ababneh MM, Al-Rukibat RK, Hananeh WM, Nasar AT, Al-Zghoul MB (2012) Detection and molecular characterization of bovine leukemia viruses from Jordan. Arch Virol 157:2343–2348CrossRefPubMed
30.
Yang Y, Kelly PJ, Bai J, Zhang R, Wang C (2016) First molecular characterization of bovine leukemia virus infections in the Caribbean. PLoS One 11:e0168379CrossRefPubMedPubMedCentral
31.
Benavides B, Munoz S, Ceriani C (2017) Molecular analysis of a fragment of bovine leukemia virus env gene by nested-PCR in dairy cows from Pasto, Nariño. Rev Med Vet 33:67–75
32.
Pluta A, Rola-Łuszczak M, Kubiś P, Balov S, Moskalik R, Choudhury B, Kuźmak J (2017) Molecular characterization of bovine leukemia virus from Moldovan dairy cattle. Arch Virol 162:1563–1576CrossRefPubMedPubMedCentral
33.
Dube S, Dolcini G, Abbott L, Mehta S, Dube D, Gutierrez S, Ceriani C, Esteban E, Ferrer J, Poiesz B (2000) The complete genomic sequence of a BLV strain from a Holstein cow from Argentina. Virology 277:379–386CrossRefPubMed
34.
Gatot JS, Callebaut I, Van Lint C, Demonté D, Kerkhofs P, Portetelle D, Burny A, Willems L, Kettmann R (2002) Bovine leukemia virus SU protein interacts with zinc, and mutations within two interacting regions differently affect viral fusion and infectivity in vivo. J Virol 76:7956–7967CrossRefPubMedPubMedCentral
Metadata
Title
Molecular detection and characterization of genotype 1 bovine leukemia virus from beef cattle in the traditional sector in Zambia
Authors
Mundia M. Phiri
Evans Kaimoyo
Katendi Changula
Isaac Silwamba
Herman M. Chambaro
Penjaninge Kapila
Masahiro Kajihara
Martin Simuunza
John Bwalya Muma
Girja S. Pandey
Ayato Takada
Aaron S. Mweene
Simbarashe Chitanga
Edgar Simulundu
Publication date
01-10-2019
Publisher
Springer Vienna
Keyword
Leukemia
Published in
Archives of Virology / Issue 10/2019
Print ISSN: 0304-8608
Electronic ISSN: 1432-8798
DOI
https://doi.org/10.1007/s00705-019-04350-6

Other articles of this Issue 10/2019

Archives of Virology 10/2019 Go to the issue

Brief Report

First detection and genetic characterization of peste des petits ruminants virus from dorcas gazelles “Gazella dorcas” in the Sudan, 2016-2017

Annotated Sequence Record

Genome characterization of the novel lytic Vibrio parahaemolyticus phage vB_VpP_BA6

Brief Report

NP protein and F protein of pigeon paramyxovirus type 1 are associated with its low pathogenicity in chickens

Annotated Sequence Record

Raoultella bacteriophage RP180, a new member of the genus Kagunavirus, subfamily Guernseyvirinae

Brief Report

MTTP polymorphisms and hepatic steatosis in individuals chronically infected with hepatitis C virus

Annotated Sequence Record

A novel ourmia-like mycovirus isolated from the plant pathogenic fungus Colletotrichum gloeosporioides
Live Webinar | 27-06-2024 | 18:00 (CEST)

Keynote webinar | Spotlight on medication adherence

Reserve your place

Live: Thursday 27th June 2024, 18:00-19:30 (CEST)

WHO estimates that half of all patients worldwide are non-adherent to their prescribed medication. The consequences of poor adherence can be catastrophic, on both the individual and population level.

Join our expert panel to discover why you need to understand the drivers of non-adherence in your patients, and how you can optimize medication adherence in your clinics to drastically improve patient outcomes.

Prof. Kevin Dolgin
Prof. Florian Limbourg
Prof. Anoop Chauhan
Developed by: Springer Medicine
Obesity Clinical Trial Summary

At a glance: The STEP trials

Read more

A round-up of the STEP phase 3 clinical trials evaluating semaglutide for weight loss in people with overweight or obesity.

Developed by: Springer Medicine

Highlights from the ACC 2024 Congress

Year in Review: Pediatric cardiology

Pediatric Cardiology Video

Watch Dr. Anne Marie Valente present the last year's highlights in pediatric and congenital heart disease in the official ACC.24 Year in Review session.

Year in Review: Pulmonary vascular disease

Cardiopulmonary Comorbidity Video

The last year's highlights in pulmonary vascular disease are presented by Dr. Jane Leopold in this official video from ACC.24.

Year in Review: Valvular heart disease

Valvular Heart Disease Video

Watch Prof. William Zoghbi present the last year's highlights in valvular heart disease from the official ACC.24 Year in Review session.

Year in Review: Heart failure and cardiomyopathies

Heart Failure Video

Watch this official video from ACC.24. Dr. Biykem Bozkurt discusses last year's major advances in heart failure and cardiomyopathies.

ACC 2024 Congress Coverage

Year in Review: Heart failure and cardiomyopathies

Heart Failure Video

Watch this official video from ACC.24. Dr. Biykem Bozkurt discusses last year's major advances in heart failure and cardiomyopathies.

Watch now

Semaglutide benefits people with type 2 diabetes and obesity-related heart failure

16-04-2024 Type 2 Diabetes News

Incentivised to exercise

11-04-2024 Lifestyle Modifications News

New intervention for STEMI-related cardiogenic shock

10-04-2024 Myocardial Infarction News

» View more highlights on the ACC 2024 congress hub page

Image Credits