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Archives of Virology
Published in: Archives of Virology 10/2019

01-10-2019 | Brief Report

NP protein and F protein of pigeon paramyxovirus type 1 are associated with its low pathogenicity in chickens

Authors: Yang Song, Yu Pei, Yawen Bu, Wenfeng Jia, Guozhong Zhang

Published in: Archives of Virology | Issue 10/2019

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Abstract

In this study, we investigated which structural proteins of pigeon paramyxovirus type 1 (PPMV-1) are responsible for its low pathogenicity in chickens. The results revealed that the pathogenicity of the virus is determined by multiple genes. The NP protein and F protein were found to have the strongest individual effect on virulence, and this effect further enhanced when the two proteins were expressed in combination. Our study highlights the influence of the NP and F proteins on the pathogenicity of PPMV-1 in chickens.
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Metadata
Title
NP protein and F protein of pigeon paramyxovirus type 1 are associated with its low pathogenicity in chickens
Authors
Yang Song
Yu Pei
Yawen Bu
Wenfeng Jia
Guozhong Zhang
Publication date
01-10-2019
Publisher
Springer Vienna
Published in
Archives of Virology / Issue 10/2019
Print ISSN: 0304-8608
Electronic ISSN: 1432-8798
DOI
https://doi.org/10.1007/s00705-019-04339-1

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