Published in:
01-01-2019 | Kidney Transplantation | Kidney Diseases (G Ciancio, Section Editor)
Use of Mannitol for Ischemia Reperfusion Injury in Kidney Transplant and Partial Nephrectomies—Review of Literature
Authors:
Jose Alejandro Lugo-Baruqui, Rajinikanth Ayyathurai, Adavan Sriram, Kothai Divya Pragatheeshwar
Published in:
Current Urology Reports
|
Issue 1/2019
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Abstract
Purpose of Review
Few procedures involve the ischemia-reperfusion injury to organs purposely. Two clear examples in urologic surgery consist on kidney transplantation and partial nephrectomies.
Recent Findings
Mannitol is an osmotic diuretic that is commonly used in partial nephrectomies and kidney transplantation to increase renal blood flow and decrease warm-ischemia-related renal injury to preserve estimated glomerular filtration rate (eGFR).
Summary
We review the current evidence for the use of mannitol and its effects on these procedures.