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International Journal of Diabetes in Developing Countries
Published in: International Journal of Diabetes in Developing Countries 3/2023

03-02-2023 | Ketoacidosis | Case Report

The youngest patient with hemi-chorea and diabetic ketoacidosis as presenting manifestation of type 1 diabetes mellitus from India

Authors: Abhijeet Vilas Botre, Vishakha Kashyap, Tushar Parikh

Published in: International Journal of Diabetes in Developing Countries | Issue 3/2023

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Abstract

Background

Type 1 diabetes mellitus (T1DM) is one of the most common endocrine diseases in children. Majority of them present with metabolic crises in the form of diabetic ketoacidosis (DKA) at diagnosis. Various levels of encephalopathy and seizures are the well-known manifestation of DKA.

Case presentation

We are reporting an 8-year-old girl who presented with hemi-chorea with DKA as a manifestation of type 1 DM which is extremely rare in literature in Asian subcontinents and has been encountered at such a young age for the first time in India.

Conclusion

T1DM with metabolic crises should always be one of the important differentials of hemi-chorea in children.
Literature
1.
2.
Mulder L, Onur O, Kleis L, Borders H, Cemeroglu AP. Atypical neurologic presentations of new onset type 1 diabetes mellitus in pediatric age group: a report of five unusual cases and review of the literature. J Pediatr Endocrinol Metab. 2014;27(7–8):749–56.PubMed
3.
4.
Alves C, Sampaio S, Barbosa V, Machado M. Acute chorea and type 1 diabetes mellitus: clinical and neuroimaging findings. Pediatr Diabetes. 2012;13(6):1–5.CrossRef
5.
Hashimoto KI, Ito Y, Tanahashi H, Hayashi M, Yamakita N, Yasuda K. Hyperglycemic chorea-ballism or acute exacerbation of Huntington’s chorea? Huntington’s disease unmasked by diabetic ketoacidosis in type 1 diabetes mellitus. J Clin Endocrinol Metab. 2012;97(9):3016–20.CrossRefPubMed
6.
7.
Satish PV, Pujitha K, Agrawal N, Mathew T, Vidyasagar S. Hemi-chorea in a patient with ketotic hyperglycemia: an unusual presentation. J Clin Diagnostic Res. 2017;11(5):OD24-5.
8.
Duckrow RB, Beard DC, Brennan RW. Regional cerebral blood flow decreases during chronic and acute hyperglycemia. Stroke. 1987;18(1):52–8.CrossRefPubMed
9.
Nath J, Jambhekar K, Rao C, Armitano E. Radiological and pathological changes in hemiballism-hemichorea with striatal hyperintensity. J Magn Reson Imaging. 2006;23(4):564–8.CrossRefPubMed
10.
Oh SH, Lee KY, Im JH, Lee MS. Chorea associated with non-ketotic hyperglycemia and hyperintensity basal ganglia lesion on T1-weighted brain MRI studya meta-analysis of 53 cases including four present cases. J Neurol Sci. 2002;200(1–2):57–62.CrossRefPubMed
11.
Mihai CM, Catrinoiu D, Stoicescu RM. Atypical onset of diabetes in a teenage girl: a case report. Cases J. 2008;1(1):1–5.CrossRef
Metadata
Title
The youngest patient with hemi-chorea and diabetic ketoacidosis as presenting manifestation of type 1 diabetes mellitus from India
Authors
Abhijeet Vilas Botre
Vishakha Kashyap
Tushar Parikh
Publication date
03-02-2023
Publisher
Springer India
Published in
International Journal of Diabetes in Developing Countries / Issue 3/2023
Print ISSN: 0973-3930
Electronic ISSN: 1998-3832
DOI
https://doi.org/10.1007/s13410-023-01171-x

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