Pancreatic adenocarcinoma (PDAC) is one of the most lethal cancers with a dismal 5-year survival rate of 11% [ 1 ]. A hallmark feature of PDAC is its extensive desmoplastic stroma, which is thought to confer biological aggressiveness [ 2 , 3 ]. It …
Authors:
Cong Xia, Jin-rong Qu, Yi-ping Jiao, Chun-qiang Lu, Ben Zhao, Rong-jun Ge, Yue Qiu, Bu-yue Cao, Qian Yu, Tian-yi Xia, Xiang-pan Meng, Yang Song, Li-hua Zhang, Xue-ying Long, Jing Ye, Zhi-min Ding, Wu Cai, Sheng-hong Ju
Chronic obstructive pulmonary disease (COPD) is the third leading cause of death globally. More than 200 million COPD cases were reported globally, including more than 3.2 million deaths in 2019 [ 1 ]. Cigarette smoking is the most important cause …
Authors:
Qiuchen Rao, Haidong Li, Qian Zhou, Ming Zhang, Xiuchao Zhao, Lei Shi, Junshuai Xie, Li Fan, Yeqing Han, Fumin Guo, Shiyuan Liu, Xin Zhou
Fetal ventriculomegaly (FVM) is the most common central nervous system (CNS) abnormality observed during pregnancy, characterized by the enlargement of a lateral ventricle to a width of 10 mm or more at any gestational age [ 1 ] with a reported …
Neoadjuvant chemotherapy (NAC) is increasingly used for breast cancer with clinically positive axillary lymph nodes (ALN) [ 1 , 2 ], necessitating accurate ALN response assessment for optimal post-NAC axillary surgical strategy [ 3 ]. While …
Authors:
Ying Fu, Yu-Tao Lei, Yu-Hong Huang, Fang Mei, Song Wang, Kun Yan, Yi-Hua Wang, Yi-Han Ma, Li-Gang Cui
Endovascular treatment (EVT) has been recognized as a first-line therapeutic strategy among the selected acute ischemic stroke caused by anterior circulation large vessel occlusion (AIS-LVO) patients in the late time window [ 1 – 3 ]. However …
Since the beginning of the ongoing coronavirus disease 2019 (COVID-19) pandemic, more than 770 million cases have been officially registered worldwide [ 1 ]. Although symptoms gradually improve in most patients, some individuals show persistent …
Authors:
Christian Wassipaul, Daria Kifjak, Ruxandra-Iulia Milos, Florian Prayer, Sebastian Roehrich, Melanie Winter, Lucian Beer, Martin L. Watzenboeck, Svitlana Pochepnia, Michael Weber, Dietmar Tamandl, Peter Homolka, Wolfgang Birkfellner, Helmut Ringl, Helmut Prosch, Benedikt H. Heidinger
Magnetic resonance imaging (MRI) has experienced significant growth in clinical use, evidenced by a more than threefold increase in procedures from 1997 to 2006 [ 1 ]. This upward trend continues, especially with the ongoing exploration into MRI’s …
Authors:
Quintin van Lohuizen, Christian Roest, Frank F. J. Simonis, Stefan J. Fransen, Thomas C. Kwee, Derya Yakar, Henkjan Huisman
Trigeminal neuralgia is characterized by paroxysmal and electric shock-like pain in the sensory distribution area of the trigeminal nerve [ 1 ]. Microvascular decompression (MVD) is one of the most commonly performed and effective surgical …
Patients with diabetes and concomitant varicose veins (VVs) experience an elevated risk of mixed arterial–venous ulcers, life-threatening infections, and venous thromboembolism [ 1 , 2 ]. Timely treatment of VVs in diabetics is crucial for delaying …
Authors:
Yuehong Liu, Bin Cao, Xinyu Wang, Jiali Zhong, Zhenyu Li, Ruchen Peng, Dong Zhao, Ning Gu, Qi Yang
Thoracic endovascular aortic repair (TEVAR) is widely regarded as the predominant treatment for patients with thoracic aortic pathologies. Aortic arch involvement is not suitable for routine standard procedures. Approximately 10–50% of patients …
Magnetic resonance imaging (MRI) is the modality of choice for many indications in paediatric imaging due to the lack of ionising radiation and its high soft-tissue contrast. However, drawbacks of the modality include long examination times and …
Authors:
André Lollert, Kim Sophie Frey, Christian Hoffmann, Markus Herbst, Jochem König, Isabella Schmeh, Frank Dette, Gundula Staatz
Acute myocarditis presents with diverse clinical manifestations. While most patients recover fully, a subset faces severe complications, such as heart failure and cardiovascular death [ 1 ]. Identifying individuals at risk of unfavorable outcomes …
Authors:
Mihály Károlyi, Malgorzata Polacin, Márton Kolossváry, Justyna M. Sokolska, Ioannis Matziris, Lucas Weber, Hatem Alkadhi, Robert Manka
Breast cancer is the most prevalent noncutaneous malignancy among women and is ranked as the second leading cause of cancer-related deaths [ 1 ]. The standard imaging tool for breast cancer screening is digital mammography. However, mammography …
Abdominal computed tomography (CT) scans are commonly utilized to assess internal organs and structures. CT exams can be performed by scanning subjects in different phases related to the use of intravascular contrast agents, which enhance the …
Authors:
Eduardo Pontes Reis, Louis Blankemeier, Juan Manuel Zambrano Chaves, Malte Engmann Kjeldskov Jensen, Sally Yao, Cesar Augusto Madid Truyts, Marc H. Willis, Scott Adams, Edson Amaro Jr, Robert D. Boutin, Akshay S. Chaudhari
Bone age (BA) represents skeletal maturity and is an important pediatric biological age that may differ from chronological age [ 1 , 2 ]. Accurate assessment of bone maturity is important for diagnosing and planning treatment for various …
Authors:
Gayoung Choi, Sungwon Ham, Bo-Kyung Je, Young-Jun Rhie, Kyung-Sik Ahn, Euddeum Shim, Mi-Jung Lee