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Nuclear Medicine and Molecular Imaging OnlineFirst articles

18-05-2024 | Prostate Cancer | Interesting image

Unsuspected Isolated Peritoneal Metastasis of Prostate Cancer Detected with Digital F-18 PSMA PET/CT Scan

We report the case of a prostate cancer (PC) patient referred to our center to perform F-18 prostate-specific membrane antigen (PSMA) digital positron emission tomography / computed tomography (PET/CT) scan for biochemical recurrence. PET/CT was …

Author:
Yazan Z. Alabed

13-05-2024 | Alzheimer's Disease | Editorial

Application of Artificial Intelligence in Nuclear Neuroimaging

Taeho Jo, Kwangsik Nho, Shannon L. Risacher, Andrew J. Saykin.

Author:
Ki-Seong Park

Open Access 02-05-2024 | Positron Emission Tomography | Original Article

Clinical Performance Evaluation of an Artificial Intelligence-Powered Amyloid Brain PET Quantification Method

The role of brain imaging in the diagnosis and treatment of neurodegenerative diseases continues to increase. This is because the brain condition must be evaluated using non-invasive methods due to the nature of brain diseases. Among various …

Authors:
Seung Kwan Kang, Mina Heo, Ji Yeon Chung, Daewoon Kim, Seong A. Shin, Hongyoon Choi, Ari Chung, Jung-Min Ha, Hoowon Kim, Jae Sung Lee

25-04-2024 | Nitroimidazoles | Review

Recent Progress in Synthesis of 99mTc-labeled Complexes with Nitroimidazoles as SPECT Probes for Targeting Tumor Hypoxia

The majority of solid tumors have hypoxia, or low oxygen levels, which is one of the hallmarks of cancer. Hypoxia was found to relate to cancer metastases and resistance to therapies, therefore, detection of hypoxia plays an important role in the …

Authors:
Anh Thu Nguyen, Hee-Kwon Kim

18-04-2024 | Computed Tomography | Review

Current Status of Cardiac CT for Nuclear Medicine Professionals: Coronary Artery Disease Evaluation

With advances in computed tomography (CT) technology over the past two decades, cardiac CT has become a noninvasive diagnostic tool for morphological evaluation of coronary artery disease (CAD) caused by atherosclerotic plaques and stenosis and …

Author:
Sung Min Ko

22-03-2024 | Pulmonary Hypertension | Original Article

Semi-Quantitative Analysis of Lung Perfusion SPECT/CT for Evaluation of Response to Balloon Pulmonary Angioplasty in Chronic Thromboembolic Pulmonary Hypertension

Chronic thromboembolic pulmonary hypertension (CTEPH) is a type of pre-capillary pulmonary hypertension classified as a World Health Organization (WHO) group IV pulmonary hypertension, and is considered to be the only curable form of pulmonary …

Authors:
Shin Ae Han, Sangwon Han, Jinho Lee, Do-Yoon Kang, Jae Seung Lee, Dae-Hee Kim, Duk-Woo Park, Jong‑Min Song, Jin-Sook Ryu, Dae Hyuk Moon

05-03-2024 | Positron Emission Tomography | Review

Recent Progress in Myocardial Perfusion Imaging Techniques

Nuclear cardiology, similar to other fields of nuclear medicine, has experience rapid advancements. Myocardial perfusion imaging (MPI), an important component of nuclear cardiology that commenced in the 1970s, plays a crucial role in the …

Authors:
Kwan Hyeong Jo, Won Jun Kang

24-02-2024 | Entecavir | Original Article

Synthesis and Biologic Evaluation of an Iodine-Labeled Entecavir Derivative for Anti-hepatitis B Virus Activity

Hepatitis B virus (HBV) infection is a serious worldwide public health problem. Currently, it is reported that more than 296 million people globally are chronically HBV infected, and nearby one million patients with chronic HBV (CHB) infection …

Authors:
Mu hua Cheng, Liang jun Xie

23-02-2024 | Meningioma | Case Report

68Ga-DOATATOC Brain PET/CT Imaging in a case of Dural Metastasis from Synovial Sarcoma

We present the case of a 70-year-old male patient who underwent a gallium-68 (68Ga)-DOTATOC brain positron emission tomography (PET)/computed tomography (CT) for the assessment of a tumorous lesion on the dura. The patient had previously undergone …

Authors:
Shin Ae Han, Jeongryul Ryu, Sang Woo Song, Jae-Seung Kim, Jin-Sook Ryu, Minyoung Oh

23-02-2024 | Interesting image

Precise Localization of Urine Leak After Renal Transplantation on Radionuclide Renography: Added Value of the Unclamped Drainage Tube and SPECT-CT

Identifying and localizing the site of post-renal transplantation urine leaks is important for patient management and treatment planning. Renal scintigraphy is a proven modality for confirming urine leaks after complicated post-renal …

Authors:
Althaf K Majeed, Om Kumar Yadav, Sameer Taywade, Rajesh Kumar, Arjun Singh Sandhu

21-02-2024 | Glioma | Review

Recent Update on PET/CT Radiotracers for Imaging Cerebral Glioma

Positron emission tomography/computed tomography (PET/CT) has dramatically altered the landscape of noninvasive glioma evaluation, offering complementary insights to those gained through magnetic resonance imaging (MRI). PET/CT scans enable a …

Authors:
Dongwoo Kim, Suk-Hyun Lee, Hee Sung Hwang, Sun Jung Kim, Mijin Yun

21-02-2024 | Osteosarcoma | Interesting image

Unilateral Increased Brown Fat Activities on 18F-FDG PET/CT in a Patient with Contralateral Anhidrosis After Surgical Treatment of Metastatic Osteosarcoma in the Upper Thoracic Spine

Authors:
Joon Ho Choi, Jin-Sook Ryu

20-02-2024 | Alzheimer's Disease | Review

Anti-amyloid Antibody Therapies for Alzheimer’s Disease

Alzheimer’s disease (AD) is the most common cause of dementia, which is characterized by a progressive neurodegenerative disorder that is extremely difficult to treat and severely reduces quality of life. Amyloid beta (Aβ) has been the primary …

Author:
Kyung Won Park

15-02-2024 | Parkinson's Disease | Review

Radionuclide Imaging of the Neuroanatomical and Neurochemical Substrate of Cognitive Decline in Parkinson’s Disease

Cognitive impairment is a frequent manifestation of Parkinson’s disease (PD), resulting in decrease in patients’ quality of life and increased societal and economic burden. However, cognitive decline in PD is highly heterogenous and the mechanisms …

Authors:
Samuel Booth, Ji Hyun Ko

14-02-2024 | Cardiomyopathy | Review

Recent Progress of Cardiac MRI for Nuclear Medicine Professionals

Recent technical innovation enables faster and more reliable cardiac magnetic resonance (CMR) imaging than before. Artificial intelligence is used in improving image resolution, fast scanning, and automated analysis of CMR. Fast CMR techniques …

Authors:
Yeon Hyeon Choe, Sung Mok Kim

06-02-2024 | Review

A Review of Machine Learning Approaches for Brain Positron Emission Tomography Data Analysis

Positron emission tomography (PET) imaging has moved forward the development of medical diagnostics and research across various domains, including cardiology, neurology, infection detection, and oncology. The integration of machine learning (ML) …

Authors:
Ke Xu, Hakmook Kang

31-01-2024 | Pancreatitis | Interesting image

Stent-Induced [68Ga]Ga-FAPI Diffuse Expression in a Patient with Pancreatic Cancer: Navigating Non-oncologic Challenges

Authors:
Akram Al-Ibraheem, Deya’ Aldeen Sweedat, Ahmed Saad Abdlkadir, Dragi Stanimirović, Habibollah Dadgar

17-01-2024 | Positron Emission Tomography | Review

Imaging Procedure and Clinical Studies of [18F]FP-CIT PET

N-3-[18F]fluoropropyl-2β-carbomethoxy-3β-4-iodophenyl nortropane ([18F]FP-CIT) is a radiopharmaceutical for dopamine transporter (DAT) imaging using positron emission tomography (PET) to detect dopaminergic neuronal degeneration in patients with …

Authors:
Changhwan Sung, Seung Jun Oh, Jae Seung Kim

15-01-2024 | Alzheimer's Disease | Review

A Key Mediator and Imaging Target in Alzheimer’s Disease: Unlocking the Role of Reactive Astrogliosis Through MAOB

Astrocytes primarily maintain physiological brain homeostasis. However, under various pathological conditions, they can undergo morphological, transcriptomic, and functional transformations, collectively referred to as reactive astrogliosis.

Authors:
Min-Ho Nam, Heesu Na, C. Justin Lee, Mijin Yun

09-01-2024 | Positron Emission Tomography | Review

Reassessing the Role of Ischemia Imaging: Insights from the ISCHEMIA Trial

Ischemia imaging plays an important role in prognostication as well as guiding decision for revascularization with known CAD, as shown in multiple observational registries. However, results from the ISCHEMIA trial (International Study of …

Authors:
Malek Nayfeh Jr, Mouaz H Al-Mallah