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Investigational New Drugs

Issue 1/2001

Content (13 Articles)

Chronic Oral Administration of CI-994: A Phase I Study

Sucharu Prakash, Brenda J. Foster, Mark Meyer, Antoinette Wozniak, Lance K. Heilbrun, Lawrence Flaherty, Mark Zalupski, Louis Radulovic, Manuel Valdivieso, Patricia M. LoRusso

Phase I Study of Irofulven (MGI 114), an Acylfulvene Illudin Analog, in Patients with Acute Leukemia

Francis Giles, Jorge Cortes, Guillermo Garcia-Manero, Stephen Kornblau, Elihu Estey, Monica Kwari, Anthony Murgo, Hagop Kantarjian

A Phase I Study of Vitamin E, 5-Fluorouracil and Leucovorin for Advanced Malignancies

Charles D. Blanke, Michael Stipanov, Jason Morrow, Mace Rothenberg, Rebecca Chinery, Yu Shyr, Robert Coffey, David H. Johnson, Steven D. Leach, R. Daniel Beauchamp

The Oral Fluorinated Pyrimidines

J.S. de Bono, C.J. Twelves

Factors Affecting the Pharmacokinetics of CPT-11: The Body Mass Index, Age and Sex are Independent Predictors of Pharmacokinetic Parameters of CPT-11

Toshimichi Miya, Tomoyuki Goya, Hirofumi Fujii, Tomoko Ohtsu, Kuniaki Itoh, Tadahiko Igarashi, Hironobu Minami, Yasutsuna Sasaki

Phase II Study of High-Dose Lovastatin in Patients with Advanced Gastric Adenocarcinoma

Won Seog Kim, Myung Min Kim, Hae Jin Choi, Sung-Soo Yoon, Mark Hong Lee, Keunchil Park, Chan H. Park, Won Ki Kang

A Phase II trial of 6-Hydroxymethylacylfulvene (MGI-114, Irofulven) in Patients with Advanced Non-Small Cell Cancer Previously Treated with Chemotherapy

Jonathan E. Dowell, David H. Johnson, John S. Rogers, Yu Shyr, Nancy McCullough, Peggy Krozely, Russell F. DeVore

Achievement of Complete Remission in Refractory Hodgkin's Disease with Prolonged Infusion of Gemcitabine

Orhan Sezer, Jan Eucker, Christian Jakob, Olaf Kaufmann, Peter Schmid, Kurt Possinger

Webinar | 19-02-2024 | 17:30 (CET)

Keynote webinar | Spotlight on antibody–drug conjugates in cancer

Antibody–drug conjugates (ADCs) are novel agents that have shown promise across multiple tumor types. Explore the current landscape of ADCs in breast and lung cancer with our experts, and gain insights into the mechanism of action, key clinical trials data, existing challenges, and future directions.

Dr. Véronique Diéras
Prof. Fabrice Barlesi
Developed by: Springer Medicine