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Investigational New Drugs

Issue 6/2023

Content (11 Articles)

Optimal first-line treatment strategies of systemic therapy for unresectable gastrointestinal neuroendocrine tumors based on the opinions of Japanese experts.

Yoshitaka Honma, Masafumi Ikeda, Susumu Hijioka, Shigemi Matsumoto, Tetsuhide Ito, Taku Aoki, Junji Furuse

Antitumor activity of the new tyrphostin briva against BRAFV600E-mutant colorectal carcinoma cells

Khaled Saleh, Mai Al Sakhen, Sana Kanaan, Salem Yasin, Michael Höpfner, Lubna Tahtamouni, Bernhard Biersack

Clinical characterization, treatment, and outcome of nivolumab-induced bullous pemphigoid

Miao Liu, Maoye Yuan, Wei Sun, Zuojun Li, Xingchen Zhou, Chunjiang Wang

Pharmacokinetics, pharmacodynamics and efficacy of pemigatinib (a selective inhibitor of fibroblast growth factor receptor 1–3) monotherapy in Chinese patients with advanced solid tumors: a phase i clinical trial

Ting Deng, Le Zhang, Yehui Shi, Guiying Bai, Yueyin Pan, Aizong Shen, Xinghua Han, Zhaoyi Yang, Mingxia Chen, Hui Zhou, Yang Luo, Shirui Zheng, Yi Ba

Therapeutic effectiveness of anlotinib combined with etoposide in extensive-stage small-cell lung cancer: a single-arm, phase II trial

  • Open Access
  • SCLC
  • Research

Yuan Wu, Xuefeng Zhou, Weiqing Zhao, Qiong Wang, Zhengxiang Han, Lifeng Wang, Wenjie Zhou, Tong Zhou, Haizhu Song, Yong Chen, Kaihua Yang, Lin Shi, Banzhou Pan, Renhong Guo, Guoren Zhou, Feng Jiang, Jifeng Feng, Bo Shen

The ATR inhibitor berzosertib acts as a radio- and chemosensitizer in head and neck squamous cell carcinoma cell lines

  • Open Access
  • Research

Julia Schnoell, Carmen Sparr, Sega Al-Gboore, Markus Haas, Faris F. Brkic, Lorenz Kadletz-Wanke, Gregor Heiduschka, Bernhard J. Jank

Phase 1/1b open-label, dose-escalation study of fruquintinib in patients with advanced solid tumors in the United States

Andrea Wang-Gillam, William Schelman, Stacey Ukrainskyj, Caly Chien, Martha Gonzalez, Zhao Yang, Marek Kania, Heather Yeckes-Rodin

Gastrointestinal signet ring cell malignancy: current advancement and future prospects

Weiping Hong, Qingjun Hu, Yuan Tan, Qianqian Duan, Qin Zhang, Dongsheng Chen, Chuang Qi, Da Wang

Women’s health knowledge hub

Elevate your patient care with our comprehensive, evidence-based medical education on women's health. Designed to help you provide exceptional care for your female patients at every stage of life, we provide expert insights into topics such as reproductive health, menopause, breast cancer and sex-specific health risks and precision medicine.

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Incorporating comprehensive genomic profiling into the standard-of-care for NSCLC and thyroid cancer

In this interactive webinar, experts Dr. Subbiah, Dr. Drilon, and Dr. Williams discuss best pathological practices within NSCLC and thyroid cancer, as well as how genomic testing can improve outcomes in clinical practice, using patient case studies as illustrations.

This content is intended only for US-based healthcare providers.

Supported by:
  • Illumina, Inc., and Eli Lilly and Company
Dr. Vivek Subbiah
Dr. Alexander Drilon
Dr. Michelle Williams
Developed by: Springer Healthcare
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Video

Elevate your expertise in aplastic anemia (Link opens in a new window)

Transform the way you care for your patients with aplastic anemia with our 3-module series using real-world case studies and expert insights. Discover why early diagnosis matters, explore the benefits and risks of current treatments, and develop tailored approaches for complex cases. 

Supported by:
  • Pfizer
Developed by: Springer Healthcare IME
Learn more