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Open Access 01-12-2021 | Intracranial Aneurysm | Research article

Neurocritical care complications and interventions influence the outcome in aneurysmal subarachnoid hemorrhage

Authors: Alexander Hammer, Frank Erbguth, Matthias Hohenhaus, Christian M. Hammer, Hannes Lücking, Markus Gesslein, Monika Killer-Oberpfalzer, Hans-Herbert Steiner, Hendrik Janssen

Published in: BMC Neurology | Issue 1/2021

Abstract

Background

This observational study was performed to show the impact of complications and interventions during neurocritical care on the outcome after aneurysmal subarachnoid hemorrhage (SAH).

Methods

We analyzed 203 cases treated for ruptured intracranial aneurysms, which were classified regarding clinical outcome after one year according to the modified Rankin Scale (mRS). We reviewed the data with reference to the occurrence of typical complications and interventions in neurocritical care units.

Results

Decompressive craniectomy (odds ratio 21.77 / 6.17 ; p < 0.0001 / p = 0.013), sepsis (odds ratio 14.67 / 6.08 ; p = 0.037 / 0.033) and hydrocephalus (odds ratio 3.71 / 6.46 ; p = 0.010 / 0.00095) were significant predictors for poor outcome and death after one year beside “World Federation of Neurosurgical Societies” (WFNS) grade (odds ratio 3.86 / 4.67 ; p < 0.0001 / p < 0.0001) and age (odds ratio 1.06 / 1.10 ; p = 0.0030 / p < 0.0001) in our multivariate analysis (binary logistic regression model).

Conclusions

In summary, decompressive craniectomy, sepsis and hydrocephalus significantly influence the outcome and occurrence of death after aneurysmal SAH.

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Title: Neurocritical care complications and interventions influence the outcome in aneurysmal subarachnoid hemorrhage
Authors: Alexander Hammer
Frank Erbguth
Matthias Hohenhaus
Christian M. Hammer
Hannes Lücking
Markus Gesslein
Monika Killer-Oberpfalzer
Hans-Herbert Steiner
Hendrik Janssen
Publication date: 01-12-2021
Publisher: BioMed Central
Keywords: Intracranial Aneurysm
Subarachnoid Hemorrhage
Septicemia
Septicemia
Hydrocephalus
Hydrocephalus
Subarachnoid Hemorrhage
Care
Hydrocephalus
Pneumonia
Tracheostomy
Published in: BMC Neurology / Issue 1/2021
Electronic ISSN: 1471-2377
DOI: https://doi.org/10.1186/s12883-021-02054-6

At a glance: The STEP trials

Springer Medicine

Neurocritical care complications and interventions influence the outcome in aneurysmal subarachnoid hemorrhage

Abstract

Background

Methods

Results

Conclusions

At a glance: The STEP trials

Springer Medicine

Abstract

Background

Methods

Results

Conclusions

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