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01-05-2021 | Insulins | Review

The consequences of hypoglycaemia

Author: Stephanie A. Amiel

Published in: Diabetologia | Issue 5/2021

Abstract

Hypoglycaemia (blood glucose concentration below the normal range) has been recognised as a complication of insulin treatment from the very first days of the discovery of insulin, and remains a major concern for people with diabetes, their families and healthcare professionals today. Acute hypoglycaemia stimulates a stress response that acts to restore circulating glucose, but plasma glucose concentrations can still fall too low to sustain normal brain function and cardiac rhythm. There are long-term consequences of recurrent hypoglycaemia, which are still not fully understood. This paper reviews our current understanding of the acute and cumulative consequences of hypoglycaemia in insulin-treated diabetes.

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Title: The consequences of hypoglycaemia
Author: Stephanie A. Amiel
Publication date: 01-05-2021
Publisher: Springer Berlin Heidelberg
Keywords: Insulins
Hypoglycemia
Insulins
Type 1 Diabetes
Published in: Diabetologia / Issue 5/2021
Print ISSN: 0012-186X
Electronic ISSN: 1432-0428
DOI: https://doi.org/10.1007/s00125-020-05366-3

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