Published in:
01-06-2013
Insights into tandem mass spectrometry for the laboratory endocrinology
Authors:
Uberto Pagotto, Flaminia Fanelli, Renato Pasquali
Published in:
Reviews in Endocrine and Metabolic Disorders
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Issue 2/2013
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Excerpt
In the last decade a great deal of data were produced by the scientific community on the analytical improvements introduced by liquid chromatography—tandem mass spectrometry (LC-MS/MS) in the research and clinical fields. This technology is nowadays recognized as the most promising for the quantitation of small molecules in biological fluids. LC-MS/MS combines the practicability of LC and the inherent elevated sensitivity and specificity of MS. Its potential in terms of improved practicability and sample throughput represent the hope for a definitive reconciliation between quality, economy and productivity of assays for clinical laboratories. …