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Reviews in Endocrine and Metabolic Disorders

Published in:

01-06-2013

HIV and thyroid dysfunction

Authors: Alan A. Parsa, Amrit Bhangoo

Published in: Reviews in Endocrine and Metabolic Disorders | Issue 2/2013

Abstract

Human Immunodeficiency virus (HIV) infection and Acquired Immunodeficiency Syndrome (AIDS) are associated with dysfunction of many endocrine organs and their axis. HIV infectivity leads to altered metabolism, poor oral intake and increased prevalence of weight loss and wasting which may have a role in thyroid dysfunction. Overt thyroid dysfunction occurs at similar rates as the general population while subclinical disease such as nonthyroidal illness (sick euthyroid syndrome), subclinical hypothyroidism and isolated low T4 levels are more frequent. Moreover, HAART therapy can complicate thyroid function further through drug interactions and the immune reconstitution inflammatory syndrome (IRIS). In this review we report the common thyroid dysfunctions associated with HIV before and after HAART therapy. We discuss presentation, diagnostic work up, treatment and follow up in each condition.

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Title: HIV and thyroid dysfunction
Authors: Alan A. Parsa
Amrit Bhangoo
Publication date: 01-06-2013
Publisher: Springer US
Published in: Reviews in Endocrine and Metabolic Disorders / Issue 2/2013
Print ISSN: 1389-9155
Electronic ISSN: 1573-2606
DOI: https://doi.org/10.1007/s11154-013-9248-6

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