Skip to main content
Top
Published in: Digestive Diseases and Sciences 3/2022

01-03-2022 | Infliximab | Multicenter Seminars: IBD (MUSE: IBD)

Rare and Well Done: Endoscopic Control of Colonic Hemorrhage in Severe Ulcerative Colitis

Authors: Shintaro Akiyama, Nathaniel A. Cohen, Joshua M. Steinberg, Scott Friedberg, Russell D. Cohen

Published in: Digestive Diseases and Sciences | Issue 3/2022

Login to get access

Excerpt

A 23-year-old male was evaluated in the ED with severe abdominal pain and bloody diarrhea. Computed tomography (CT) of the abdomen and pelvis showed pancolitis with the most severe inflammation seen in the distal colon; subsequent flexible sigmoidoscopy revealed severe colitis to the extent of the exam. Histological evaluation confirmed chronic inflammatory colitis with moderate activity. He was diagnosed with ulcerative colitis (UC) (Montreal classification E3). Oral prednisone 40 mg daily was initially prescribed followed by vedolizumab 300 mg every 8 weeks. Despite these therapies, he ultimately required hospitalization due to symptom persistence. …
Literature
1.
go back to reference Podugu A, Tandon K, Castro FJ. Crohn’s disease presenting as acute gastrointestinal hemorrhage. World J Gastroenterol. 2016;22:4073–4078.CrossRefPubMedCentral Podugu A, Tandon K, Castro FJ. Crohn’s disease presenting as acute gastrointestinal hemorrhage. World J Gastroenterol. 2016;22:4073–4078.CrossRefPubMedCentral
2.
go back to reference Robert JH, Sachar DB, Aufses AH Jr et al. Management of severe hemorrhage in ulcerative colitis. Am J Surg. 1990;159:550–555.CrossRefPubMedCentral Robert JH, Sachar DB, Aufses AH Jr et al. Management of severe hemorrhage in ulcerative colitis. Am J Surg. 1990;159:550–555.CrossRefPubMedCentral
3.
go back to reference Pardi DS, Loftus EV Jr, Tremaine WJ et al. Acute major gastrointestinal hemorrhage in inflammatory bowel disease. Gastrointest Endosc. 1999;49:153–157.CrossRefPubMedCentral Pardi DS, Loftus EV Jr, Tremaine WJ et al. Acute major gastrointestinal hemorrhage in inflammatory bowel disease. Gastrointest Endosc. 1999;49:153–157.CrossRefPubMedCentral
4.
go back to reference Yokoyama T, Masaki T, Ono M et al. Per anal suturing of a bleeding ulcer to achieve successful hemostasis of massive hemorrhage associated with ulcerative colitis: report of two cases. Surg Today. 1998;28:1179–1181.CrossRefPubMedCentral Yokoyama T, Masaki T, Ono M et al. Per anal suturing of a bleeding ulcer to achieve successful hemostasis of massive hemorrhage associated with ulcerative colitis: report of two cases. Surg Today. 1998;28:1179–1181.CrossRefPubMedCentral
5.
go back to reference Miranda-Bautista J, Dieguez L, Rodriguez-Rosales G et al. Cases report: severe colonic bleeding in ulcerative colitis is refractory to selective transcatheter arterial embolization. BMC Gastroenterol. 2019;19:55.CrossRefPubMedCentral Miranda-Bautista J, Dieguez L, Rodriguez-Rosales G et al. Cases report: severe colonic bleeding in ulcerative colitis is refractory to selective transcatheter arterial embolization. BMC Gastroenterol. 2019;19:55.CrossRefPubMedCentral
6.
go back to reference Mallant-Hent R, van Bodegraven AA, Meuwissen SG et al. Alternative approach to massive gastrointestinal bleeding in ulcerative colitis: highly selective transcatheter embolization. Eur J Gastroenterol Hepatol. 2003;15:189–193.CrossRefPubMedCentral Mallant-Hent R, van Bodegraven AA, Meuwissen SG et al. Alternative approach to massive gastrointestinal bleeding in ulcerative colitis: highly selective transcatheter embolization. Eur J Gastroenterol Hepatol. 2003;15:189–193.CrossRefPubMedCentral
7.
go back to reference Yoshida Y, Kawaguchi A, Mataki N et al. Endoscopic treatment of massive lower GI hemorrhage in two patients with ulcerative colitis. Gastrointest Endosc. 2001;54:779–781.CrossRefPubMedCentral Yoshida Y, Kawaguchi A, Mataki N et al. Endoscopic treatment of massive lower GI hemorrhage in two patients with ulcerative colitis. Gastrointest Endosc. 2001;54:779–781.CrossRefPubMedCentral
8.
go back to reference Kaya S, Hatemi I, Hamzaoglu I et al. Massive haemorrhage induced by low molecular weight heparin in a patient with steroid refractory ulcerative colitis. Scand J Gastroenterol. 2004;39:613.CrossRefPubMedCentral Kaya S, Hatemi I, Hamzaoglu I et al. Massive haemorrhage induced by low molecular weight heparin in a patient with steroid refractory ulcerative colitis. Scand J Gastroenterol. 2004;39:613.CrossRefPubMedCentral
9.
go back to reference Aniwan S, Eakpongpaisit S, Imraporn B et al. Infliximab stopped severe gastrointestinal bleeding in Crohn’s disease. World J Gastroenterol. 2012;18:2730–2734.CrossRefPubMedCentral Aniwan S, Eakpongpaisit S, Imraporn B et al. Infliximab stopped severe gastrointestinal bleeding in Crohn’s disease. World J Gastroenterol. 2012;18:2730–2734.CrossRefPubMedCentral
10.
go back to reference Kim KJ, Han BJ, Yang SK et al. Risk factors and outcome of acute severe lower gastrointestinal bleeding in Crohn’s disease. Dig Liver Dis. 2012;44:723–728.CrossRef Kim KJ, Han BJ, Yang SK et al. Risk factors and outcome of acute severe lower gastrointestinal bleeding in Crohn’s disease. Dig Liver Dis. 2012;44:723–728.CrossRef
Metadata
Title
Rare and Well Done: Endoscopic Control of Colonic Hemorrhage in Severe Ulcerative Colitis
Authors
Shintaro Akiyama
Nathaniel A. Cohen
Joshua M. Steinberg
Scott Friedberg
Russell D. Cohen
Publication date
01-03-2022
Publisher
Springer US
Published in
Digestive Diseases and Sciences / Issue 3/2022
Print ISSN: 0163-2116
Electronic ISSN: 1573-2568
DOI
https://doi.org/10.1007/s10620-022-07446-3

Other articles of this Issue 3/2022

Digestive Diseases and Sciences 3/2022 Go to the issue
Obesity Clinical Trial Summary

At a glance: The STEP trials

A round-up of the STEP phase 3 clinical trials evaluating semaglutide for weight loss in people with overweight or obesity.

Developed by: Springer Medicine

Highlights from the ACC 2024 Congress

Year in Review: Pediatric cardiology

Watch Dr. Anne Marie Valente present the last year's highlights in pediatric and congenital heart disease in the official ACC.24 Year in Review session.

Year in Review: Pulmonary vascular disease

The last year's highlights in pulmonary vascular disease are presented by Dr. Jane Leopold in this official video from ACC.24.

Year in Review: Valvular heart disease

Watch Prof. William Zoghbi present the last year's highlights in valvular heart disease from the official ACC.24 Year in Review session.

Year in Review: Heart failure and cardiomyopathies

Watch this official video from ACC.24. Dr. Biykem Bozkurt discuss last year's major advances in heart failure and cardiomyopathies.