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Published in: Child's Nervous System 8-9/2005

01-08-2005 | Special Annual Issue

Individualized treatment of craniopharyngioma in children: ways and means

Authors: J. C. Marchal, O. Klein, P. Thouvenot, V. Bernier, C. Moret, P. Chastagner

Published in: Child's Nervous System | Issue 8-9/2005

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Abstract

Background

Medium- and long-term prognosis of craniopharyngioma is overwhelmed by the risks of hypothalamic and visual impairment. This problem has been underestimated for a long time because the major concern for the neurosurgeon was the risk of recurrences, their best prevention being thought to be complete tumour resection. Today, we know that radical surgery not only is not an absolute guarantee against recurrences but also can cause hypothalamic and visual complications.

Methods

The authors suggest that instead of complete removal, the first choice treatment should be, when possible, a less aggressive, multistaged and personalized treatment. In this perspective they focus on other therapeutic methods: endocavity treatment of cysts with rhenium-186, triconformational radiotherapy, radiosurgery, and widespread use of the trans-sphenoidal approach.

Conclusions

These simple methods should reduce the risks of visual aggravation and metabolic syndrome.
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Metadata
Title
Individualized treatment of craniopharyngioma in children: ways and means
Authors
J. C. Marchal
O. Klein
P. Thouvenot
V. Bernier
C. Moret
P. Chastagner
Publication date
01-08-2005
Publisher
Springer-Verlag
Published in
Child's Nervous System / Issue 8-9/2005
Print ISSN: 0256-7040
Electronic ISSN: 1433-0350
DOI
https://doi.org/10.1007/s00381-005-1211-8

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