Skip to main content
Top
Published in: AIDS Research and Therapy 1/2022

Open Access 01-12-2022 | Immunodeficiency | Research

Thirty-five years (1986–2021) of HIV/AIDS in Nigeria: bibliometric and scoping analysis

Authors: Henshaw Uchechi Okoroiwu, Ekementeabasi Aniebo Umoh, Edet Effiong Asanga, Uwem Okon Edet, Michael Raymond Atim-Ebim, Edum Abang Tangban, Elizabeth Nkagafel Mbim, Cynthia Amarachi Odoemena, Victor Kanu Uno, Joseph Okon Asuquo, Otu Otu Effiom-Ekaha, Ogechukwu C. Dozie-Nwakile, Ikenna K. Uchendu, Chidiebere Peter Echieh, Kingsley John Emmanuel, Regina Idu Ejemot-Nwadiaro, Glory Mbe Egom Nja, Adaeze Oreh, Mercy Ogechi Uchenwa, Emmanuel Chukwuma Ufornwa, Ndidi Patience Nwaiwu, Christopher Ogar Ogar, Ani Nkang, Obinna Justice Kabiri, F. Javier Povedano-Montero

Published in: AIDS Research and Therapy | Issue 1/2022

Login to get access

Abstract

Background

Acquired immunodeficiency syndrome (AIDS) is an acquired defect of the cellular immunity associated with the infection by the human immunodeficiency virus (HIV). The disease has reached pandemic proportion and has been considered a public health concern. This study is aimed at analyzing the trend of HIV/AIDS research in Nigeria.

Method

We used the PUBMED database to a conduct bibliometric analysis of HIV/AIDS-related research in Nigeria from 1986 to 2021 employing “HIV”, “AIDS”, “acquired immunodeficiency syndrome”, “Human immunodeficiency virus”, and “Nigeria” as search description. The most common bibliometric indicators were applied for the selected publications.

Result

The number of scientific research articles retrieved for HIV/AIDS-related research in Nigeria was 2796. Original research was the predominant article type. Articles authored by 4 authors consisted majority of the papers. The University of Ibadan was found to be the most productive institution. Institutions in the United States dominated external production with the University of Maryland at the top. The most utilized journal was PLoS ONE. While Iliyasu Z. was the most productive principal author, Crowel TA. was the overall most productive author with the highest collaborative strength. The keyword analysis using overlay visualization showed a gradual shift from disease characteristics to diagnosis, treatment and prevention. Trend in HIV/AIDS research in Nigeria is increasing yet evolving. Four articles were retracted while two had an expression of concern.

Conclusion

The growth of scientific literature in HIV/AIDS-related research in Nigeria was found to be high and increasing. However, the hotspot analysis still shows more unexplored grey areas in future.
Appendix
Available only for authorised users
Literature
2.
go back to reference Balogun AS. HIV/AIDS epidemic in the history of Nigeria, 1986–2007. J Hist Soc Nigeria. 2014; 166–176. Balogun AS. HIV/AIDS epidemic in the history of Nigeria, 1986–2007. J Hist Soc Nigeria. 2014; 166–176.
3.
go back to reference Gallo RC and Luc Montagnier. AIDS: The scourge of the new age. The Guardian, Wednesday, November 30, 1998. P. 10. The authors of this article, which was curled from Scientific American of October 1988, were the doctors who isolated the AIDS virus in France and the United States later named HIV in 1986. Gallo RC and Luc Montagnier. AIDS: The scourge of the new age. The Guardian, Wednesday, November 30, 1998. P. 10. The authors of this article, which was curled from Scientific American of October 1988, were the doctors who isolated the AIDS virus in France and the United States later named HIV in 1986.
4.
go back to reference Entonu PE, Agwale SM. A review of the epidemiology, prevention and treatment of Human Immunodeficiency Virus in Nigeria. Braz J Infect Dis. 2007;11(6):579–90.CrossRef Entonu PE, Agwale SM. A review of the epidemiology, prevention and treatment of Human Immunodeficiency Virus in Nigeria. Braz J Infect Dis. 2007;11(6):579–90.CrossRef
5.
go back to reference Barre-Sinoussi F, Chermann JC, Rey F, Nugeyre MT, Chamaret S, et al. Isolation of a T-Lymphotropic retrovirus from a patient at risk for acquired immune deficiency syndrome (AIDS). Science. 1983;220:868–71.CrossRef Barre-Sinoussi F, Chermann JC, Rey F, Nugeyre MT, Chamaret S, et al. Isolation of a T-Lymphotropic retrovirus from a patient at risk for acquired immune deficiency syndrome (AIDS). Science. 1983;220:868–71.CrossRef
6.
go back to reference Gallo R, Salahuddin SZ, Popovic M, Shearer GM, et al. Frequent detection and isolation of cytopathic retroviruses (HILV-III) from patients with AIDS and at risk for AIDS. Science. 1984;224:500–3.CrossRef Gallo R, Salahuddin SZ, Popovic M, Shearer GM, et al. Frequent detection and isolation of cytopathic retroviruses (HILV-III) from patients with AIDS and at risk for AIDS. Science. 1984;224:500–3.CrossRef
7.
go back to reference Schupbath J, Popovic M, Gilden R, et al. Serological analysis of a subgroup of human T-Lymphotropic retroviruses (HILV-III) associated with AIDS. Science. 1984;224:503–5.CrossRef Schupbath J, Popovic M, Gilden R, et al. Serological analysis of a subgroup of human T-Lymphotropic retroviruses (HILV-III) associated with AIDS. Science. 1984;224:503–5.CrossRef
8.
go back to reference Greene WC. A history of AIDS: looking back to see ahead. Eur J Immunol. 2007;37(S1):594–5102.CrossRef Greene WC. A history of AIDS: looking back to see ahead. Eur J Immunol. 2007;37(S1):594–5102.CrossRef
9.
go back to reference Levy JA, Hoffman AD, Kramer SM, Landis JA, Shimabukuro JM, Oshiro LS. Isolation of lymphocytopathic retroviruses from San Francisco patients with AIDS. Science. 1984;225:840–2.CrossRef Levy JA, Hoffman AD, Kramer SM, Landis JA, Shimabukuro JM, Oshiro LS. Isolation of lymphocytopathic retroviruses from San Francisco patients with AIDS. Science. 1984;225:840–2.CrossRef
10.
go back to reference Coffin J, Haase A, Levy JA, Montagnier L, et al. What to call the AIDS virus? Nature. 1986;321:10.CrossRef Coffin J, Haase A, Levy JA, Montagnier L, et al. What to call the AIDS virus? Nature. 1986;321:10.CrossRef
11.
go back to reference Soga Odubona. Reported Cases. Sunday Times. December 4, 1988. P. 12. Soga Odubona. Reported Cases. Sunday Times. December 4, 1988. P. 12.
14.
go back to reference Federal Ministry of Health. Technical Report: 2003 National HIV Seroprevalence Sentinel Survey. April, 2004. Federal Ministry of Health. Technical Report: 2003 National HIV Seroprevalence Sentinel Survey. April, 2004.
16.
go back to reference Awofala AA, Ogundele OE. HIV epidemiology in Nigeria. Saudi J Biol Sci. 2018;25(4):697–703.CrossRef Awofala AA, Ogundele OE. HIV epidemiology in Nigeria. Saudi J Biol Sci. 2018;25(4):697–703.CrossRef
17.
go back to reference Federal Ministry of Health. National HIV & AIDS and Reproductive Health Survey 2012. NARHS plus II. Federal Ministry of Health. National HIV & AIDS and Reproductive Health Survey 2012. NARHS plus II.
19.
go back to reference Ufornwa EC, Okoroiwu HU. HIV post exposure prophylaxis in a tertiary health care institution in Southeastern Nigeria: Clients’ characteristics and indications for initiation. Nigeria Health J. 2021;21(3):149–68. Ufornwa EC, Okoroiwu HU. HIV post exposure prophylaxis in a tertiary health care institution in Southeastern Nigeria: Clients’ characteristics and indications for initiation. Nigeria Health J. 2021;21(3):149–68.
20.
go back to reference Coco-Bassey SB, Asemota EA, Okoroiwu HU, Etura JE, Efiong EE, Inyang IJ, Uko EK. Glutathione, Glutathione peroxidase and some hematological parameters of HIV-Seropositive subjects attending clinic in University of Calabar Teaching Hospital, Calabar. Nigeria BMC Infect Dis. 2019;19:944.CrossRef Coco-Bassey SB, Asemota EA, Okoroiwu HU, Etura JE, Efiong EE, Inyang IJ, Uko EK. Glutathione, Glutathione peroxidase and some hematological parameters of HIV-Seropositive subjects attending clinic in University of Calabar Teaching Hospital, Calabar. Nigeria BMC Infect Dis. 2019;19:944.CrossRef
22.
go back to reference Okoroiwu HU, Lopez-Munoz F, Povedano-Montero FJ. Bibliometric analysis of global Lassa fever research (1970–2017): 9 47-year study. BMC Infect Dis. 2018;18:639.CrossRef Okoroiwu HU, Lopez-Munoz F, Povedano-Montero FJ. Bibliometric analysis of global Lassa fever research (1970–2017): 9 47-year study. BMC Infect Dis. 2018;18:639.CrossRef
23.
go back to reference Okoroiwu HU, Lopez-Munoz F, Povedano-Montero FJ. Bibliometric analysis of global sickle cell disease research from 1997–2017. Hematol Transfusion Cell There. 2022;44(2):186–96.CrossRef Okoroiwu HU, Lopez-Munoz F, Povedano-Montero FJ. Bibliometric analysis of global sickle cell disease research from 1997–2017. Hematol Transfusion Cell There. 2022;44(2):186–96.CrossRef
24.
go back to reference Romero-Riano E, Guerrero-Santander CD, Martinez-Ardila HE. Agronomy research co-authorship networks in agricultural innovation systems. Rev UIS Ingenieras. 2021;20(1):161–76. Romero-Riano E, Guerrero-Santander CD, Martinez-Ardila HE. Agronomy research co-authorship networks in agricultural innovation systems. Rev UIS Ingenieras. 2021;20(1):161–76.
27.
go back to reference Iskanius P. Open Innovation in University-Industry Collaborations Communities of practice”, in Open Innovation: A multifaceted perspective. Vol 1. Faculty of Technology, University of Oulu. P.O Box 4200. Finland: World Scientific Publishing Co. Pte. Ltd. 2016: pp 443–474. Iskanius P. Open Innovation in University-Industry Collaborations Communities of practice”, in Open Innovation: A multifaceted perspective. Vol 1. Faculty of Technology, University of Oulu. P.O Box 4200. Finland: World Scientific Publishing Co. Pte. Ltd. 2016: pp 443–474.
28.
go back to reference Lardner T, Akinosho T, Momah A, Uzoatu UM, and Usani A. Killer virus strikes fear. This week. 1987; 16–26. Lardner T, Akinosho T, Momah A, Uzoatu UM, and Usani A. Killer virus strikes fear. This week. 1987; 16–26.
31.
go back to reference Oladosu O, Abimbola O, Bolaji O. Bibliometric analysis of biotechnology research in Nigeria. SLIS Connecting. 2019;8(2):5.CrossRef Oladosu O, Abimbola O, Bolaji O. Bibliometric analysis of biotechnology research in Nigeria. SLIS Connecting. 2019;8(2):5.CrossRef
32.
go back to reference Jegede SL, Jegede SW, Boyo FU, Odofin OO, Adeyinya OE. A bibliometric analysis on Lassa fever research trend in Nigeria. Int J Innovat Sci Res Technol. 2019;4(6):563–70. Jegede SL, Jegede SW, Boyo FU, Odofin OO, Adeyinya OE. A bibliometric analysis on Lassa fever research trend in Nigeria. Int J Innovat Sci Res Technol. 2019;4(6):563–70.
33.
go back to reference Ani OE, Onyancha OB. A measure of research productivity of Nigerian Universities: ABibliometric Analysis, In Proceedings of the ISSI 2011 conference: 13th International Conference of International Society for Scientometrics and Informetrics. Durban, South Africa. 2011: PP 04–07. Ani OE, Onyancha OB. A measure of research productivity of Nigerian Universities: ABibliometric Analysis, In Proceedings of the ISSI 2011 conference: 13th International Conference of International Society for Scientometrics and Informetrics. Durban, South Africa. 2011: PP 04–07.
42.
go back to reference Egwumyenga EJ. Dystrophies and associated crisis in research and academic publications ijn Nigerian Universities. Anthropologist. 2008;10(4):245–50.CrossRef Egwumyenga EJ. Dystrophies and associated crisis in research and academic publications ijn Nigerian Universities. Anthropologist. 2008;10(4):245–50.CrossRef
43.
go back to reference Baro EE, Bosah GE, Obi IC. Research funding opportunities and challenges; a survey of academic staff members in Nigerian Tertiary Institutions. Bottom Line. 2017;30(1):47–64.CrossRef Baro EE, Bosah GE, Obi IC. Research funding opportunities and challenges; a survey of academic staff members in Nigerian Tertiary Institutions. Bottom Line. 2017;30(1):47–64.CrossRef
44.
go back to reference Akpochafo WP. Revitalizing research in Nigerian Universities for national. Educ Res Rev. 2009;4(5):247–51. Akpochafo WP. Revitalizing research in Nigerian Universities for national. Educ Res Rev. 2009;4(5):247–51.
45.
go back to reference Bako. Universities, research and development in Nigeria: time for paradigmatic shift. Paper prepared from the 11th General Assembly of CODESRIA on Rethinking African Development Beyond Impasse: Toward Alternative, Maputo. 2005. Bako. Universities, research and development in Nigeria: time for paradigmatic shift. Paper prepared from the 11th General Assembly of CODESRIA on Rethinking African Development Beyond Impasse: Toward Alternative, Maputo. 2005.
46.
go back to reference Itiola AJ, Goga AE, Ramokolo V. Trends and predictors of mother-to-child transmission of HIV in an era of protocol changes: findings from two large health facilities in North East Nigeria. PLoS ONE. 2019;14(11): e0224670.CrossRef Itiola AJ, Goga AE, Ramokolo V. Trends and predictors of mother-to-child transmission of HIV in an era of protocol changes: findings from two large health facilities in North East Nigeria. PLoS ONE. 2019;14(11): e0224670.CrossRef
47.
go back to reference Olopha PO, et al. Spatial pattern and determinants of sufficient knowledge of mother-to-child transmission of HIV and its prevention among Nigerian women. PLoS ONE. 2021;16(6):e0253705.CrossRef Olopha PO, et al. Spatial pattern and determinants of sufficient knowledge of mother-to-child transmission of HIV and its prevention among Nigerian women. PLoS ONE. 2021;16(6):e0253705.CrossRef
48.
go back to reference Olakunle BO, Adeyinka DA, Olawepo JO, Phaer JR, Ezigbu CE, et al. Towards the elimination of mother-to-child transmission of HIV in Nigeria: a health system perspective of the achievements and challenges. Int Health. 2019;11(4):240–9.CrossRef Olakunle BO, Adeyinka DA, Olawepo JO, Phaer JR, Ezigbu CE, et al. Towards the elimination of mother-to-child transmission of HIV in Nigeria: a health system perspective of the achievements and challenges. Int Health. 2019;11(4):240–9.CrossRef
49.
go back to reference Yakasai HB, Panas RM, Kadrie MB. Knowledge of Mother-To-Child transmission of HIV as a prediction of HIV testing in some women of child bearing age in Nigeria. Sci World J. 2021;16(3):266–71. Yakasai HB, Panas RM, Kadrie MB. Knowledge of Mother-To-Child transmission of HIV as a prediction of HIV testing in some women of child bearing age in Nigeria. Sci World J. 2021;16(3):266–71.
50.
go back to reference Harrison NE, Oruka KE, Agbaim UC, Adegbite OA, et al. Prevention of mother-to-child transmission of HIV: knowledge, attitude and factors influencing active participation among HIV-positive men in a military Health facility in Lagos. Southwestern Nigeria Open J Prevent Med. 2020;10(8):233–53.CrossRef Harrison NE, Oruka KE, Agbaim UC, Adegbite OA, et al. Prevention of mother-to-child transmission of HIV: knowledge, attitude and factors influencing active participation among HIV-positive men in a military Health facility in Lagos. Southwestern Nigeria Open J Prevent Med. 2020;10(8):233–53.CrossRef
51.
go back to reference Ball P. Paper trail reveals references go unread by citing authors. Nature. 2002;420:594.CrossRef Ball P. Paper trail reveals references go unread by citing authors. Nature. 2002;420:594.CrossRef
52.
go back to reference Simkin MV, Roychowdhury VP. Read before you cite! Complex Syst. 2003;14(3):269–74. Simkin MV, Roychowdhury VP. Read before you cite! Complex Syst. 2003;14(3):269–74.
Metadata
Title
Thirty-five years (1986–2021) of HIV/AIDS in Nigeria: bibliometric and scoping analysis
Authors
Henshaw Uchechi Okoroiwu
Ekementeabasi Aniebo Umoh
Edet Effiong Asanga
Uwem Okon Edet
Michael Raymond Atim-Ebim
Edum Abang Tangban
Elizabeth Nkagafel Mbim
Cynthia Amarachi Odoemena
Victor Kanu Uno
Joseph Okon Asuquo
Otu Otu Effiom-Ekaha
Ogechukwu C. Dozie-Nwakile
Ikenna K. Uchendu
Chidiebere Peter Echieh
Kingsley John Emmanuel
Regina Idu Ejemot-Nwadiaro
Glory Mbe Egom Nja
Adaeze Oreh
Mercy Ogechi Uchenwa
Emmanuel Chukwuma Ufornwa
Ndidi Patience Nwaiwu
Christopher Ogar Ogar
Ani Nkang
Obinna Justice Kabiri
F. Javier Povedano-Montero
Publication date
01-12-2022
Publisher
BioMed Central
Published in
AIDS Research and Therapy / Issue 1/2022
Electronic ISSN: 1742-6405
DOI
https://doi.org/10.1186/s12981-022-00489-6

Other articles of this Issue 1/2022

AIDS Research and Therapy 1/2022 Go to the issue
Live Webinar | 27-06-2024 | 18:00 (CEST)

Keynote webinar | Spotlight on medication adherence

Live: Thursday 27th June 2024, 18:00-19:30 (CEST)

WHO estimates that half of all patients worldwide are non-adherent to their prescribed medication. The consequences of poor adherence can be catastrophic, on both the individual and population level.

Join our expert panel to discover why you need to understand the drivers of non-adherence in your patients, and how you can optimize medication adherence in your clinics to drastically improve patient outcomes.

Prof. Kevin Dolgin
Prof. Florian Limbourg
Prof. Anoop Chauhan
Developed by: Springer Medicine
Obesity Clinical Trial Summary

At a glance: The STEP trials

A round-up of the STEP phase 3 clinical trials evaluating semaglutide for weight loss in people with overweight or obesity.

Developed by: Springer Medicine