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Published in: Internal and Emergency Medicine 4/2022

01-02-2022 | Hypoxemia | EM - ORIGINAL

SIMEU position paper on non-invasive respiratory support in COVID-19 pneumonia

Authors: Roberto Cosentini, Paolo Groff, Anna Maria Brambilla, Renzo Camajori Todeschini, Gianfilippo Gangitano, Stella Ingrassia, Roberta Marino, Francesca Nori, Fiammetta Pagnozzi, Francesco Panero, Rodolfo Ferrari, SIMEU NIV Group collaborators

Published in: Internal and Emergency Medicine | Issue 4/2022

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Abstract

The rapid worldwide spread of the Coronavirus disease (COVID-19) crisis has put health systems under pressure to a level never experienced before, putting intensive care units in a position to fail to meet an exponentially growing demand. The main clinical feature of the disease is a progressive arterial hypoxemia which rapidly leads to ARDS which makes the use of intensive care and mechanical ventilation almost inevitable. The difficulty of health systems to guarantee a corresponding supply of resources in intensive care, together with the uncertain results reported in the literature with respect to patients who undergo early conventional ventilation, make the search for alternative methods of oxygenation and ventilation and potentially preventive of the need for tracheal intubation, such as non-invasive respiratory support techniques particularly valuable. In this context, the Emergency Department, located between the area outside the hospital and hospital ward and ICU, assumes the role of a crucial junction, due to the possibility of applying these techniques at a sufficiently early stage and being able to rapidly evaluate their effectiveness. This position paper describes the indications for the use of non-invasive respiratory support techniques in respiratory failure secondary to COVID-19-related pneumonia, formulated by the Non-invasive Ventilation Faculty of the Italian Society of Emergency Medicine (SIMEU) on the base of what is available in the literature and on the authors' direct experience. Rationale, literature, tips & tricks, resources, risks and expected results, and patient interaction will be discussed for each one of the escalating non-invasive respiratory techniques: standard oxygen, HFNCO, CPAP, NIPPV, and awake self-repositioning. The final chapter describes our suggested approach to the failing patient.
Literature
6.
go back to reference Rochwerg B, Brochard L, Elliott MW et al (2017) Official ERS/ATS clinical practice guidelines: noninvasive ventilation for acute respiratory failure. Eur Respir J 50:1602426PubMedCrossRef Rochwerg B, Brochard L, Elliott MW et al (2017) Official ERS/ATS clinical practice guidelines: noninvasive ventilation for acute respiratory failure. Eur Respir J 50:1602426PubMedCrossRef
7.
go back to reference Gattinoni L, Coppola S, Cressoni M, Chiumello D (2020) COVID-19 does not lead to a “Typical” acute respiratory distress syndrome. Am J Respir Crit Care Med 201(10):1299–1300PubMedCrossRefPubMedCentral Gattinoni L, Coppola S, Cressoni M, Chiumello D (2020) COVID-19 does not lead to a “Typical” acute respiratory distress syndrome. Am J Respir Crit Care Med 201(10):1299–1300PubMedCrossRefPubMedCentral
8.
go back to reference Potus F, Mai V, Lebret M et al (2020) Novel insights on the pulmonary vascular consequences of COVID19. Am J Physiol Lung Cell Mol Physiol 319:L277-288PubMedCrossRefPubMedCentral Potus F, Mai V, Lebret M et al (2020) Novel insights on the pulmonary vascular consequences of COVID19. Am J Physiol Lung Cell Mol Physiol 319:L277-288PubMedCrossRefPubMedCentral
9.
go back to reference Dohnt S, Derom E, Van Braekel E et al (2020) The pathophysiology of “happy” hypoxemia in COVID-19. Respir Res 21:198CrossRef Dohnt S, Derom E, Van Braekel E et al (2020) The pathophysiology of “happy” hypoxemia in COVID-19. Respir Res 21:198CrossRef
10.
go back to reference Gattinoni L, Chiumello D, Caironi P et al (2020) Covid-19 pneumonia: different respiratory treatments for different phenotypes? Intensive Care Med 14:1–4 Gattinoni L, Chiumello D, Caironi P et al (2020) Covid-19 pneumonia: different respiratory treatments for different phenotypes? Intensive Care Med 14:1–4
11.
go back to reference Brochard L, Slutsky A, Pesenti A (2017) Mechanical ventilation to minimize progression of lung injury in acute respiratory failure. Am J Respir Crit Care Med 195(4):438–442PubMedCrossRef Brochard L, Slutsky A, Pesenti A (2017) Mechanical ventilation to minimize progression of lung injury in acute respiratory failure. Am J Respir Crit Care Med 195(4):438–442PubMedCrossRef
12.
go back to reference Grieco DL, Menga LS, Eleuteri D, Antonelli M (2019) Patient self-inflicted lung injury: implications for acute hypoxemic respiratory failure and ARDS patients on non-invasive support. Minerva Anesthesiol 85(9):1014–1023 Grieco DL, Menga LS, Eleuteri D, Antonelli M (2019) Patient self-inflicted lung injury: implications for acute hypoxemic respiratory failure and ARDS patients on non-invasive support. Minerva Anesthesiol 85(9):1014–1023
13.
go back to reference Yoshida T, Grieco DL, Brochard L, Fujino Y (2019) Patients self-inflicted lung injury and positive end-expiratory pressure for safe spontaneous breathing. Curr Opin Crit Care 25(2):192–198PubMedCrossRef Yoshida T, Grieco DL, Brochard L, Fujino Y (2019) Patients self-inflicted lung injury and positive end-expiratory pressure for safe spontaneous breathing. Curr Opin Crit Care 25(2):192–198PubMedCrossRef
14.
go back to reference Yoshida T, Amato MBP, Kavanagh BP, Fujino Y (2019) Impact of spontaneous breathing during mechanical ventilation in acute respiratory distress syndrome. Curr Opin Crit Care 25(2):192–198PubMedCrossRef Yoshida T, Amato MBP, Kavanagh BP, Fujino Y (2019) Impact of spontaneous breathing during mechanical ventilation in acute respiratory distress syndrome. Curr Opin Crit Care 25(2):192–198PubMedCrossRef
18.
go back to reference Longhini F, Bruni A, Garofalo E et al (2020) Helmet continuous positive airway pressure and prone positioning: a proposal for an early management of COVID19 patients. Pulmunology 26(4):186–191CrossRef Longhini F, Bruni A, Garofalo E et al (2020) Helmet continuous positive airway pressure and prone positioning: a proposal for an early management of COVID19 patients. Pulmunology 26(4):186–191CrossRef
19.
go back to reference Hui DS, Chow BK, Lo T, Ng SS, Ko FW, Gin T, Chan MTV (2015) Exhaled air dispersion during noninvasive ventilation via helmets and a total facemask. Chest 147(5):1336–1343PubMedCrossRef Hui DS, Chow BK, Lo T, Ng SS, Ko FW, Gin T, Chan MTV (2015) Exhaled air dispersion during noninvasive ventilation via helmets and a total facemask. Chest 147(5):1336–1343PubMedCrossRef
22.
go back to reference Cabrini L, Landoni G, Oriani A (2015) Noninvasive ventilation and survival in acute care settings: a comprehensive systematic review and meta-analysis of randomized controlled trials. Crit Care Med 43:880–888PubMedCrossRef Cabrini L, Landoni G, Oriani A (2015) Noninvasive ventilation and survival in acute care settings: a comprehensive systematic review and meta-analysis of randomized controlled trials. Crit Care Med 43:880–888PubMedCrossRef
23.
go back to reference Carteaux G, Millan-Guilarte T, De Prost N et al (2016) Failure of noninvasive ventilation for de novo acute hypoxemic respiratory failure: role of tidal volume. Crit Care Med 44:282–290PubMedCrossRef Carteaux G, Millan-Guilarte T, De Prost N et al (2016) Failure of noninvasive ventilation for de novo acute hypoxemic respiratory failure: role of tidal volume. Crit Care Med 44:282–290PubMedCrossRef
24.
go back to reference WHO (2020) Clinical management of severe acute respiratory infection when Novel coronavirus (2019-nCoV) infection is suspected: Interim Guidance. WHO/nCoV/Clinical/2020.3 January 28 WHO (2020) Clinical management of severe acute respiratory infection when Novel coronavirus (2019-nCoV) infection is suspected: Interim Guidance. WHO/nCoV/Clinical/2020.3 January 28
27.
go back to reference Majumdar SR, Eurich DT, Gamble J-M, Senthilselvan A, Marrie TJ (2011) Oxygen saturations less than 92% are associated with major adverse events in outpatients with pneumonia: a population-based cohort study. Clin Infect Dis 52(3):325–331PubMedCrossRef Majumdar SR, Eurich DT, Gamble J-M, Senthilselvan A, Marrie TJ (2011) Oxygen saturations less than 92% are associated with major adverse events in outpatients with pneumonia: a population-based cohort study. Clin Infect Dis 52(3):325–331PubMedCrossRef
28.
go back to reference Jiang B, Wei B (2020) Oxygen therapy strategies and techniques to treat hypoxia in COVID-19 patients. Eur Rev Med Pharmacol Sci 24:10239–10246PubMed Jiang B, Wei B (2020) Oxygen therapy strategies and techniques to treat hypoxia in COVID-19 patients. Eur Rev Med Pharmacol Sci 24:10239–10246PubMed
29.
go back to reference Whittle JS, Sacchetti IP, Atwood C, Rosenberg MS (2020) Respiratory support for adult patients with COVID-19. JACEP Open 1:95–101CrossRefPubMedCentral Whittle JS, Sacchetti IP, Atwood C, Rosenberg MS (2020) Respiratory support for adult patients with COVID-19. JACEP Open 1:95–101CrossRefPubMedCentral
30.
go back to reference Hui DS, Chan MT, Chow B (2014) Aerosol dispersion during various respiratory therapies: a risk assessment model of nosocomial infection to health care workers. Hong Kong Med J 20(suppl 4):9–13PubMed Hui DS, Chan MT, Chow B (2014) Aerosol dispersion during various respiratory therapies: a risk assessment model of nosocomial infection to health care workers. Hong Kong Med J 20(suppl 4):9–13PubMed
34.
go back to reference Schwabbauer N, Berg B, Blumenstock G et al (2014) Nasal High flow oxygen therapy in patients with hypoxic respiratory failure: effect on functional and subjective respiratory parameters compared to conventional oxygen therapy and non-invasive ventilation (NIV). BMC Anesthesiol 14:66PubMedCrossRefPubMedCentral Schwabbauer N, Berg B, Blumenstock G et al (2014) Nasal High flow oxygen therapy in patients with hypoxic respiratory failure: effect on functional and subjective respiratory parameters compared to conventional oxygen therapy and non-invasive ventilation (NIV). BMC Anesthesiol 14:66PubMedCrossRefPubMedCentral
35.
go back to reference Dogani B, Manson F, Resman F et al (2021) The application of an oxygen mask, without supplemental oxygen, improved oxygenation in patients with severe COVID-19 already treated with high-flow nasal cannula. Crit Care 25(1):319PubMedCrossRefPubMedCentral Dogani B, Manson F, Resman F et al (2021) The application of an oxygen mask, without supplemental oxygen, improved oxygenation in patients with severe COVID-19 already treated with high-flow nasal cannula. Crit Care 25(1):319PubMedCrossRefPubMedCentral
36.
go back to reference Wang K, Wei Z, Ji L et al (2020) The experience of high-flow nasal cannula in hospitalized patients with 209 novel coronavirus-infected pneumonia in two hospitals of Chongqing, China. Ann Intensive Care 10:37PubMedCrossRefPubMedCentral Wang K, Wei Z, Ji L et al (2020) The experience of high-flow nasal cannula in hospitalized patients with 209 novel coronavirus-infected pneumonia in two hospitals of Chongqing, China. Ann Intensive Care 10:37PubMedCrossRefPubMedCentral
37.
go back to reference Vianello A, Arcaro G, Molena B et al (2020) High flow nasal cannula oxygen therapy to treat patients with hypoxemic acute respiratory failure consequent to SARS-CoV-2 infection. Thorax 75(11):998–1000PubMedCrossRef Vianello A, Arcaro G, Molena B et al (2020) High flow nasal cannula oxygen therapy to treat patients with hypoxemic acute respiratory failure consequent to SARS-CoV-2 infection. Thorax 75(11):998–1000PubMedCrossRef
38.
go back to reference Patel M, Gangemi A, Marron R et al (2020) Retrospective analysis of high flow nasal therapy in Covid-19-related moderate-to-severe hypoxaemic failure. BMJ Open Respir Res 7(1):e000650PubMedCrossRefPubMedCentral Patel M, Gangemi A, Marron R et al (2020) Retrospective analysis of high flow nasal therapy in Covid-19-related moderate-to-severe hypoxaemic failure. BMJ Open Respir Res 7(1):e000650PubMedCrossRefPubMedCentral
40.
go back to reference Calligaro GL, Lalla U, Audley G et al. The utility of high-flow nasal oxygen for severe COVID-19 pneumonia in a resource-constrained setting: a multicenter prospective observational study. EClinicalMedicine 2020; 28:100570 Calligaro GL, Lalla U, Audley G et al. The utility of high-flow nasal oxygen for severe COVID-19 pneumonia in a resource-constrained setting: a multicenter prospective observational study. EClinicalMedicine 2020; 28:100570
41.
go back to reference Xia J, Yi Z, Ni L et al (2020) High-flow nasal oxygen in Coronavirus disease, 2019 patients with acute hypoxemic respiratory failure: a multicenter, retrospective cohort study. Crit Care Med 48:e1079PubMedCrossRefPubMedCentral Xia J, Yi Z, Ni L et al (2020) High-flow nasal oxygen in Coronavirus disease, 2019 patients with acute hypoxemic respiratory failure: a multicenter, retrospective cohort study. Crit Care Med 48:e1079PubMedCrossRefPubMedCentral
42.
go back to reference Kang BJ, Koh Y, Lim CM et al (2015) Failure of high-flow nasal cannula therapy may delay intubation and increase mortality. Intensive Care Med 41(4):623–632PubMedCrossRef Kang BJ, Koh Y, Lim CM et al (2015) Failure of high-flow nasal cannula therapy may delay intubation and increase mortality. Intensive Care Med 41(4):623–632PubMedCrossRef
43.
go back to reference Roca O, Caralt B, Messika J et al (2019) An index combining respiratory rate and oxygenation to predict outcome of nasal High-flow therapy. Am J Respir Crit Care med 199(11):1368–1376PubMedCrossRef Roca O, Caralt B, Messika J et al (2019) An index combining respiratory rate and oxygenation to predict outcome of nasal High-flow therapy. Am J Respir Crit Care med 199(11):1368–1376PubMedCrossRef
45.
go back to reference Demoule A, Vieillard Baron A, Darmon M et al (2020) High-flow nasal cannula in critically ill patients with severe COVID-19. Am J Respir Crit Care Med 202:1039–1042PubMedCrossRefPubMedCentral Demoule A, Vieillard Baron A, Darmon M et al (2020) High-flow nasal cannula in critically ill patients with severe COVID-19. Am J Respir Crit Care Med 202:1039–1042PubMedCrossRefPubMedCentral
46.
go back to reference Grieco DL, Menga LS, Cesarano M et al (2021) Effect of Helmet noninvasive ventilation vs high-flow nasal oxygen on days free of respiratory support in patients with COVID-19 and moderate to severe hypoxemic respiratory failure. JAMA 325(17):1731–1743PubMedCrossRef Grieco DL, Menga LS, Cesarano M et al (2021) Effect of Helmet noninvasive ventilation vs high-flow nasal oxygen on days free of respiratory support in patients with COVID-19 and moderate to severe hypoxemic respiratory failure. JAMA 325(17):1731–1743PubMedCrossRef
48.
go back to reference Raboud J, Shigayeva A, McGeer A et al (2020) Risk factors for SARS transmission from patients requiring intubation: a multicenter investigation in Toronto, Canada. PLoS ONE 5(5):e10717CrossRef Raboud J, Shigayeva A, McGeer A et al (2020) Risk factors for SARS transmission from patients requiring intubation: a multicenter investigation in Toronto, Canada. PLoS ONE 5(5):e10717CrossRef
49.
go back to reference Tran K, Cimon K, Severn M et al (2012) Aerosol generating procedures and risk of transmission of acute respiratory infections to healthcare workers: a systematic review. PLoS ONE 7(4):e35797PubMedCrossRefPubMedCentral Tran K, Cimon K, Severn M et al (2012) Aerosol generating procedures and risk of transmission of acute respiratory infections to healthcare workers: a systematic review. PLoS ONE 7(4):e35797PubMedCrossRefPubMedCentral
51.
go back to reference Robba C, Battaglini D, Ball L et al (2020) Distinct phenotypes require distinct respiratory management strategies in severe COVID-19. Respir Physiol Neurobiol 279:103455PubMedCrossRefPubMedCentral Robba C, Battaglini D, Ball L et al (2020) Distinct phenotypes require distinct respiratory management strategies in severe COVID-19. Respir Physiol Neurobiol 279:103455PubMedCrossRefPubMedCentral
58.
go back to reference Alviset S, Riller Q, Aboab J et al (2020) Continuous positive airway pressure (CPAP) face-mask ventilation is an easy and cheap option to manage a massive influx of patients presenting acute respiratory failure during the SARS-CoV-2 outbreak: a retrospective cohort study. PLoS ONE 15(10):e0240645PubMedCrossRefPubMedCentral Alviset S, Riller Q, Aboab J et al (2020) Continuous positive airway pressure (CPAP) face-mask ventilation is an easy and cheap option to manage a massive influx of patients presenting acute respiratory failure during the SARS-CoV-2 outbreak: a retrospective cohort study. PLoS ONE 15(10):e0240645PubMedCrossRefPubMedCentral
61.
go back to reference Burns GP, Lane ND, Tedd HM et al (2020) Improved survival following ward-based non-invasive pressure support for severe hypoxia in a cohort of frail patients with Covid-19: retrospective analysis from a UK teaching hospital. BMJ Open Respir Res 7(1):e000621PubMedCrossRefPubMedCentral Burns GP, Lane ND, Tedd HM et al (2020) Improved survival following ward-based non-invasive pressure support for severe hypoxia in a cohort of frail patients with Covid-19: retrospective analysis from a UK teaching hospital. BMJ Open Respir Res 7(1):e000621PubMedCrossRefPubMedCentral
62.
go back to reference Coppo A, Bellani G, Winterton D et al (2020) Feasibility and physiological effects of prone positioning in non-intubated patients with acute respiratory failure due to COVID-19 (PRON-COVID): a prospective cohort study. Lancet Respir Med 8(8):765–774PubMedCrossRefPubMedCentral Coppo A, Bellani G, Winterton D et al (2020) Feasibility and physiological effects of prone positioning in non-intubated patients with acute respiratory failure due to COVID-19 (PRON-COVID): a prospective cohort study. Lancet Respir Med 8(8):765–774PubMedCrossRefPubMedCentral
63.
go back to reference Di Domenico SL, Coen D, Bergamaschi M, et al (2020) Clinical characteristics and respiratory support of 310 Covid-19 patients, diagnosed at the emergency room: a single-center retrospective study. pp 1–10 Di Domenico SL, Coen D, Bergamaschi M, et al (2020) Clinical characteristics and respiratory support of 310 Covid-19 patients, diagnosed at the emergency room: a single-center retrospective study. pp 1–10
64.
go back to reference Duca A, Memaj I, Zanardi F et al (2020) Severity of respiratory failure and outcome of patients needing a ventilatory support in the Emergency Department during Italian novel coronavirus SARS-CoV2 outbreak: preliminary data on the role of helmet CPAP and non-invasive positive pressure ventilation. EClinicalMedicine 24:100419PubMedCrossRefPubMedCentral Duca A, Memaj I, Zanardi F et al (2020) Severity of respiratory failure and outcome of patients needing a ventilatory support in the Emergency Department during Italian novel coronavirus SARS-CoV2 outbreak: preliminary data on the role of helmet CPAP and non-invasive positive pressure ventilation. EClinicalMedicine 24:100419PubMedCrossRefPubMedCentral
65.
go back to reference Franco C, Facciolongo N, Tonelli R et al (2020) Feasibility and clinical impact of out-of-ICU non-invasive respiratory support in patients with COVID-19 related pneumonia. Eur Respir J 56(5):2002130PubMedCrossRefPubMedCentral Franco C, Facciolongo N, Tonelli R et al (2020) Feasibility and clinical impact of out-of-ICU non-invasive respiratory support in patients with COVID-19 related pneumonia. Eur Respir J 56(5):2002130PubMedCrossRefPubMedCentral
66.
go back to reference Hallifax RJ, Porter BML, Elder PJD et al (2020) Successful awake proning is associated with improved clinical outcomes in patients with COVID-19: single-centre high-dependency unit experience. BMJ Open Respir Res 7(1):e000678PubMedCrossRef Hallifax RJ, Porter BML, Elder PJD et al (2020) Successful awake proning is associated with improved clinical outcomes in patients with COVID-19: single-centre high-dependency unit experience. BMJ Open Respir Res 7(1):e000678PubMedCrossRef
69.
go back to reference Mukhtar A, Lofty A, Hasanin A et al (2020) Outcome of non-invasive ventilation in Covid-19 critically ill patients: a retrospective observational study. Anaesth Crit Care Pain Med 39:579–580PubMedCrossRefPubMedCentral Mukhtar A, Lofty A, Hasanin A et al (2020) Outcome of non-invasive ventilation in Covid-19 critically ill patients: a retrospective observational study. Anaesth Crit Care Pain Med 39:579–580PubMedCrossRefPubMedCentral
70.
go back to reference Nightingale R, Nwosu N, Kutubudin F et al (2020) Is continuous positive airway pressure (CPAP) a new standard of care for type 1 respiratory failure in Covid-19 patients? A retrospective observational study of a dedicated Covid-19 CPAP service. BMJ Open Respir Res 7(1):e000639PubMedCrossRefPubMedCentral Nightingale R, Nwosu N, Kutubudin F et al (2020) Is continuous positive airway pressure (CPAP) a new standard of care for type 1 respiratory failure in Covid-19 patients? A retrospective observational study of a dedicated Covid-19 CPAP service. BMJ Open Respir Res 7(1):e000639PubMedCrossRefPubMedCentral
72.
go back to reference Oranger M, Gonzalez-Bermejo J, Dacosta-Noble F et al (2020) Continuous positive airway pressure to avoid intubation in SARS-CoV-2 pneumonia: a two-period retrospective case-control study. Eur Respir J 56:2001692PubMedCrossRefPubMedCentral Oranger M, Gonzalez-Bermejo J, Dacosta-Noble F et al (2020) Continuous positive airway pressure to avoid intubation in SARS-CoV-2 pneumonia: a two-period retrospective case-control study. Eur Respir J 56:2001692PubMedCrossRefPubMedCentral
75.
go back to reference Privitera D, Angaroni L, Capsoni N et al (2020) Flowchart for non-invasive ventilation support in COVID-19 patients from a northern Italy Emergency Department. Intern Emerg Med 15(5):767–771PubMedCrossRefPubMedCentral Privitera D, Angaroni L, Capsoni N et al (2020) Flowchart for non-invasive ventilation support in COVID-19 patients from a northern Italy Emergency Department. Intern Emerg Med 15(5):767–771PubMedCrossRefPubMedCentral
76.
go back to reference Radovanovic D, Rizzi M, Pini S et al (2020) Helmet CPAP to treat acute hypoxemic respiratory failure in patients with Covid-19: a management strategy proposal. J Clin Med 9:1191CrossRefPubMedCentral Radovanovic D, Rizzi M, Pini S et al (2020) Helmet CPAP to treat acute hypoxemic respiratory failure in patients with Covid-19: a management strategy proposal. J Clin Med 9:1191CrossRefPubMedCentral
78.
go back to reference Cammarota G, Esposito T, Azzolina D, Cosentini R, Menzella F, Aliberti S, Coppadoro A, Bellani G, Foti G, Grasselli G, Cecconi M, Pesenti A, Vitacca M, Lawton T, Ranieri VM, Di Domenico SL, Resta O, Gidaro A, Potalivo A, Nardi G, Brusasco C, Tesoro S, Navalesi P, Vaschetto R, De Robertis E (2021) Noninvasive respiratory support outside the intensive care unit for acute respiratory failure related to coronavirus-19 disease: a systematic review and meta-analysis. Crit Care 25(1):268. https://doi.org/10.1186/s13054-021-03697-0CrossRefPubMedPubMedCentral Cammarota G, Esposito T, Azzolina D, Cosentini R, Menzella F, Aliberti S, Coppadoro A, Bellani G, Foti G, Grasselli G, Cecconi M, Pesenti A, Vitacca M, Lawton T, Ranieri VM, Di Domenico SL, Resta O, Gidaro A, Potalivo A, Nardi G, Brusasco C, Tesoro S, Navalesi P, Vaschetto R, De Robertis E (2021) Noninvasive respiratory support outside the intensive care unit for acute respiratory failure related to coronavirus-19 disease: a systematic review and meta-analysis. Crit Care 25(1):268. https://​doi.​org/​10.​1186/​s13054-021-03697-0CrossRefPubMedPubMedCentral
83.
go back to reference Hui DS, Chow BK, Lo T et al (2019) Exhaled air dispersion during high-flow nasal cannula therapy versus CPAP via different masks. Eur Respir J 53:1802339PubMedCrossRef Hui DS, Chow BK, Lo T et al (2019) Exhaled air dispersion during high-flow nasal cannula therapy versus CPAP via different masks. Eur Respir J 53:1802339PubMedCrossRef
86.
go back to reference Whittle JS, Pavlov I, Sacchetti A et al (2020) Respiratory support for adult patients with COVID-19. J Am Coll Emerg Phys Open 1(2):95–101 Whittle JS, Pavlov I, Sacchetti A et al (2020) Respiratory support for adult patients with COVID-19. J Am Coll Emerg Phys Open 1(2):95–101
94.
go back to reference Ferioli M, Cisternino C, Leo V, Pisani L, Palange P, Nava S (2020) Protecting healthcare workers from SARS-CoV-2 infection: practical indications. Eur Respir Rev 29(155):200068PubMedCrossRefPubMedCentral Ferioli M, Cisternino C, Leo V, Pisani L, Palange P, Nava S (2020) Protecting healthcare workers from SARS-CoV-2 infection: practical indications. Eur Respir Rev 29(155):200068PubMedCrossRefPubMedCentral
98.
go back to reference Aboab J, Louis B, Jonson B, Brochard L (2006) Relation between PaO2/FIO2 ratio and FIO2: a mathematical description. Intensive Care Med 32:1494–1497PubMedCrossRef Aboab J, Louis B, Jonson B, Brochard L (2006) Relation between PaO2/FIO2 ratio and FIO2: a mathematical description. Intensive Care Med 32:1494–1497PubMedCrossRef
103.
go back to reference Kangelaris KN, Ware LB, Wang CY et al (2016) Timing of intubation and clinical outcomes in adults with acute respiratory distress syndrome. Crit Care Med 44(1):120–129PubMedCrossRefPubMedCentral Kangelaris KN, Ware LB, Wang CY et al (2016) Timing of intubation and clinical outcomes in adults with acute respiratory distress syndrome. Crit Care Med 44(1):120–129PubMedCrossRefPubMedCentral
108.
go back to reference Daugherty Biddison EL, Faden REL, Howard S, Gwon HS et al (2019) Too many patients. A framework to guide statewide allocation of scarce mechanical ventilation during disasters. Chest 155(4):848–854PubMedCrossRef Daugherty Biddison EL, Faden REL, Howard S, Gwon HS et al (2019) Too many patients. A framework to guide statewide allocation of scarce mechanical ventilation during disasters. Chest 155(4):848–854PubMedCrossRef
Metadata
Title
SIMEU position paper on non-invasive respiratory support in COVID-19 pneumonia
Authors
Roberto Cosentini
Paolo Groff
Anna Maria Brambilla
Renzo Camajori Todeschini
Gianfilippo Gangitano
Stella Ingrassia
Roberta Marino
Francesca Nori
Fiammetta Pagnozzi
Francesco Panero
Rodolfo Ferrari
SIMEU NIV Group collaborators
Publication date
01-02-2022
Publisher
Springer International Publishing
Published in
Internal and Emergency Medicine / Issue 4/2022
Print ISSN: 1828-0447
Electronic ISSN: 1970-9366
DOI
https://doi.org/10.1007/s11739-021-02906-6

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