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Critical Care
Published in: Critical Care 1/2020

Open Access 01-12-2020 | Hypoxemia | Research Letter

Development of a work of breathing scale and monitoring need of intubation in COVID-19 pneumonia

Authors: Mylene Apigo, Jeffrey Schechtman, Nyembezi Dhliwayo, Mohammed Al Tameemi, Raúl J. Gazmuri

Published in: Critical Care | Issue 1/2020

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Excerpt

COVID-19 pneumonia presents in most patients with scattered areas of lung involvement within healthy lungs displaying hypoxemia and tachypnea but with relatively minor reductions in lung compliance [1, 2]. Noninvasive ventilation and high-flow nasal cannula (HFNC) are reasonable initial interventions reserving endotracheal intubation for worsening disease severity evidenced by increased work of breathing (WOB), risking respiratory muscle fatigue leading to hypoventilation, hypoxemia, and cardiac arrest and large transpulmonary pressure swings risking patient self-inflicted lung injury (SILI) [3, 4]. …
Literature
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Gattinoni L, Chiumello D, Caironi P, Busana M, Romitti F, Brazzi L, et al. COVID-19 pneumonia: different respiratory treatments for different phenotypes? Intensive Care Med. 2020;46(6):1099–102.CrossRef
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Marini JJ, Gattinoni L. Management of COVID-19 respiratory distress. JAMA. 2020;24:10.
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Brochard L, Slutsky A, Pesenti A. Mechanical ventilation to minimize progression of lung injury in acute respiratory failure. Am J Respir Crit Care Med. 2017;195(4):438–42.CrossRef
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Tonelli R, Fantini R, Tabbì L, Castaniere I, Pisani L, Pellegrino MR, et al. Inspiratory effort assessment by esophageal manometry early predicts noninvasive ventilation outcome in de novo respiratory failure: a pilot study. Am J Respir Crit Care Med. 2020;10:2512OC.
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Gattinoni L, Giosa L, Bonifazi M, Pasticci I, Busana M, Macri M, et al. Targeting transpulmonary pressure to prevent ventilator-induced lung injury. Expert Rev Respir Med. 2019;13(8):737–46.CrossRef
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Metadata
Title
Development of a work of breathing scale and monitoring need of intubation in COVID-19 pneumonia
Authors
Mylene Apigo
Jeffrey Schechtman
Nyembezi Dhliwayo
Mohammed Al Tameemi
Raúl J. Gazmuri
Publication date
01-12-2020
Publisher
BioMed Central
Published in
Critical Care / Issue 1/2020
Electronic ISSN: 1364-8535
DOI
https://doi.org/10.1186/s13054-020-03176-y

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