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Published in: Intensive Care Medicine 5/2019

01-05-2019 | Hypotension | What's New in Intensive Care

Norepinephrine in septic shock

Authors: Glenn Hernández, Jean-Louis Teboul, Jan Bakker

Published in: Intensive Care Medicine | Issue 5/2019

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Excerpt

Norepinephrine (NE) is both an alpha1- and beta1-agonist, and is therefore able to increase vascular tone and contractility [1]. Recent guidelines recommend NE as the first-line vasopressor in septic shock [2]. However, because septic shock is a syndrome that results from a variable combination of decreased venous return, myocardial depression and decreased vascular tone, the place for NE in initial resuscitation is not straightforward. …
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Metadata
Title
Norepinephrine in septic shock
Authors
Glenn Hernández
Jean-Louis Teboul
Jan Bakker
Publication date
01-05-2019
Publisher
Springer Berlin Heidelberg
Published in
Intensive Care Medicine / Issue 5/2019
Print ISSN: 0342-4642
Electronic ISSN: 1432-1238
DOI
https://doi.org/10.1007/s00134-018-5499-8

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