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Published in: Heart and Vessels 2/2021

01-02-2021 | Hypercholesterolemia | Original Article

Achilles tendon thickening is associated with higher incidence of adverse cardiovascular event in patients with coronary artery disease

Authors: Takuya Hashimoto, Yoshiyasu Minami, Kiyoshi Asakura, Masahiro Katamine, Ayami Kato, Aritomo Katsura, Toshimitsu Sato, Yusuke Muramatsu, Ryota Kakizaki, Kazuhiro Fujiyoshi, Kohki Ishida, Ryo Kameda, Kentaro Meguro, Takao Shimohama, Junya Ako

Published in: Heart and Vessels | Issue 2/2021

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Abstract

Achilles tendon thickening (ATT) is a marker of high risk for coronary artery disease (CAD). However, the association between the presence of ATT and the incidence of cardiovascular events in patients with CAD is unclear. A total of 406 consecutive patients who underwent percutaneous coronary intervention (PCI) and ATT assessment were analyzed. ATT was defined as the Achilles tendon thickness of 9 mm or more on radiography. The incidence of major adverse cardiovascular events (MACE) at 1-year was compared between patients with ATT and those without ATT. MACE included cardiac death, non-fatal myocardial infarction, stroke, target vessel revascularization (TVR), and non-TVR. ATT was found in 67 patients (16.5%). The incidence of cardiac death (3.2 vs. 0.0%, p = 0.001), TVR (12.7 vs. 4.0%, p = 0.005) and MACE (20.6 vs. 9.6%, p = 0.011) was significantly higher in the ATT group than the no ATT group. Patients with ATT had significantly higher incidence of cardiac death (5.6 vs. 0%, p < 0.001) than those without ATT even if they did not meet the diagnostic criteria of familial hypercholesterolemia. A multivariate model demonstrated that ATT was independently associated with the MACE at 1-year (Hazard ratio, 2.09; 95% Confidence Interval, 1.09–4.00, p = 0.026). The presence of ATT was independently associated with 1-year recurrence of cardiovascular events in patients with CAD undergoing PCI. Assessment of ATT might be useful for risk stratification of secondary cardiovascular events.
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Metadata
Title
Achilles tendon thickening is associated with higher incidence of adverse cardiovascular event in patients with coronary artery disease
Authors
Takuya Hashimoto
Yoshiyasu Minami
Kiyoshi Asakura
Masahiro Katamine
Ayami Kato
Aritomo Katsura
Toshimitsu Sato
Yusuke Muramatsu
Ryota Kakizaki
Kazuhiro Fujiyoshi
Kohki Ishida
Ryo Kameda
Kentaro Meguro
Takao Shimohama
Junya Ako
Publication date
01-02-2021
Publisher
Springer Japan
Published in
Heart and Vessels / Issue 2/2021
Print ISSN: 0910-8327
Electronic ISSN: 1615-2573
DOI
https://doi.org/10.1007/s00380-020-01679-w

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