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Published in: Journal of Urban Health 6/2019

01-12-2019 | Human Immunodeficiency Virus

HIV Stigma, Mental Health, and Alcohol Use Disorders among People Living with HIV/AIDS in New Orleans

Authors: Erica A. Felker-Kantor, Maeve E. Wallace, Aubrey Spriggs Madkour, Dustin T. Duncan, Katherine Andrinopoulos, Katherine Theall

Published in: Journal of Urban Health | Issue 6/2019

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Abstract

Evidence suggests that HIV-related stigma is a contributing factor to mental health and substance use problems among people living with HIV (PLWH). Limited research, however, has examined the differential effects that multiple stigma constructs, specifically, anticipated, enacted, and internalized stigma may have on mental health and alcohol use disorders among PLWH. Furthermore, no studies have examined this relationship within the larger context of urban life stressors. The purpose of this study was to examine associations of an overall HIV-related stigma measure and four HIV stigma subscales on depression, anxiety, and hazardous drinking among a sample of 380 PLWH in New Orleans. Log-Poisson models with generalized estimating equations were used to estimate relative risks (RR) and 95% confidence intervals (CI). A test of interaction was used to determine presence of effect modification by urban life stressors. Overall, higher levels of HIV-stigma were associated with depressive symptoms (RR 1.67, 95% CI 1.25, 2.23), anxiety symptoms (RR 1.91, 95% CI 1.17, 3.12), and hazardous drinking (RR 1.45, 95% CI 1.02, 2.05). Internalized HIV-stigma (measured using the negative self-image subscale) was associated with all three outcomes and had the highest magnitude point estimates across the four stigma subscales. Urban life stressors, measured by the Urban Life Stressors Scale (ULSS), modified the association between HIV-related stigma and mental health and alcohol use disorders (P < 0.2), highlighting the importance for examining the larger urban environmental context. Findings from this study may inform interventions to reduce HIV-related stigma operating at the individual and structural level.
Literature
1.
go back to reference Logie C, Gadalla TM. Meta-analysis of health and demographic correlates of stigma towards people living with HIV. AIDS Care. 2009;21(6):742–53.PubMedCrossRef Logie C, Gadalla TM. Meta-analysis of health and demographic correlates of stigma towards people living with HIV. AIDS Care. 2009;21(6):742–53.PubMedCrossRef
2.
go back to reference Ciesla JA, Roberts JE. Meta-analysis of the relationship between HIV infection and risk for depressive disorders. Am J Psychiatry. 2001;158(5):725–30.PubMedCrossRef Ciesla JA, Roberts JE. Meta-analysis of the relationship between HIV infection and risk for depressive disorders. Am J Psychiatry. 2001;158(5):725–30.PubMedCrossRef
3.
go back to reference Bogart LM, Wagner GJ, Galvan FH, Landrine H, Klein DJ, Sticklor LA. Perceived discrimination and mental health symptoms among black men with HIV. Cult Divers Ethn Minor Psychol. 2011;17(3):295–302.CrossRef Bogart LM, Wagner GJ, Galvan FH, Landrine H, Klein DJ, Sticklor LA. Perceived discrimination and mental health symptoms among black men with HIV. Cult Divers Ethn Minor Psychol. 2011;17(3):295–302.CrossRef
4.
go back to reference Bing EF, Burnam MA, Longshore D, et al. Psychiatric disorders and drug use among human immunodeficiency virus-infected adults in the United States. Arch Gen Psychiatry. 2001;58(8):721–8.PubMedCrossRef Bing EF, Burnam MA, Longshore D, et al. Psychiatric disorders and drug use among human immunodeficiency virus-infected adults in the United States. Arch Gen Psychiatry. 2001;58(8):721–8.PubMedCrossRef
5.
go back to reference Gore-Felton C, Koopman C. Traumatic experiences: harbinger of risk behavior among HIV-positive adults. J Trauma Dissociation. 2002;3(4):125–35.CrossRef Gore-Felton C, Koopman C. Traumatic experiences: harbinger of risk behavior among HIV-positive adults. J Trauma Dissociation. 2002;3(4):125–35.CrossRef
6.
go back to reference Kessler RC, Chiu WT, Demler O, Walters EE. Prevalence, severity, and comorbidity of twelve-month DSM-IV disorders in the National Comorbidity Survey Replication (NCS-R). Arch Gen Psychiatry. 2005;62(6):617–27.PubMedPubMedCentralCrossRef Kessler RC, Chiu WT, Demler O, Walters EE. Prevalence, severity, and comorbidity of twelve-month DSM-IV disorders in the National Comorbidity Survey Replication (NCS-R). Arch Gen Psychiatry. 2005;62(6):617–27.PubMedPubMedCentralCrossRef
7.
go back to reference Durvasula R, Miller T. Substance abuse treatment in persons with HIV/AIDS: challenges in managing triple diagnosis. Behav Med. 2014;40(2):43–52.PubMedCrossRef Durvasula R, Miller T. Substance abuse treatment in persons with HIV/AIDS: challenges in managing triple diagnosis. Behav Med. 2014;40(2):43–52.PubMedCrossRef
8.
go back to reference UNAIDS. On the fast-track to end AIDS by 2030: focus on location and population. Geneva: UNAIDS; 2015. UNAIDS. On the fast-track to end AIDS by 2030: focus on location and population. Geneva: UNAIDS; 2015.
9.
go back to reference Rueda S, Mitra S, Chen S, Gogolishvili D, Globerman J, et al. Examining the associations between HIV-related stigma and health outcomes in people living with HIV/AIDS: a series of meta-analyses. BMJ Open. 2016;6(7):e011453.PubMedPubMedCentralCrossRef Rueda S, Mitra S, Chen S, Gogolishvili D, Globerman J, et al. Examining the associations between HIV-related stigma and health outcomes in people living with HIV/AIDS: a series of meta-analyses. BMJ Open. 2016;6(7):e011453.PubMedPubMedCentralCrossRef
10.
go back to reference Rintamaki LS, Davis TC, Skripkauskas S, Bennett CL, Wolf MS. Social stigma concerns and HIV medication adherence. AIDS Patient Care STDs. 2005;20:359–68.CrossRef Rintamaki LS, Davis TC, Skripkauskas S, Bennett CL, Wolf MS. Social stigma concerns and HIV medication adherence. AIDS Patient Care STDs. 2005;20:359–68.CrossRef
11.
go back to reference Vanable P, Carey M, Blair D, Littlewood R. Impact of HIV-related stigma on health behaviors and psychological adjustment among HIV-positive men and women. AIDS Behav. 2006;10(5):473–82.PubMedPubMedCentralCrossRef Vanable P, Carey M, Blair D, Littlewood R. Impact of HIV-related stigma on health behaviors and psychological adjustment among HIV-positive men and women. AIDS Behav. 2006;10(5):473–82.PubMedPubMedCentralCrossRef
12.
go back to reference Tucker JS, Burnam MA, Sherbourne CD, Kung FY, Gifford AL. Substance use and mental health correlates of nonadherence to antiretroviral medications in a sample of patients with human immunodeficiency virus infection. Am J Med. 2003;114(7):573–80.PubMedCrossRef Tucker JS, Burnam MA, Sherbourne CD, Kung FY, Gifford AL. Substance use and mental health correlates of nonadherence to antiretroviral medications in a sample of patients with human immunodeficiency virus infection. Am J Med. 2003;114(7):573–80.PubMedCrossRef
13.
go back to reference Chander G, Lau B, Moore RD. Hazardous alcohol use: a risk factor for non-adherence and lack of suppression in HIV infection. J Acquir Immune Defic Syndr. 2006;43(4):411–7.PubMedPubMedCentralCrossRef Chander G, Lau B, Moore RD. Hazardous alcohol use: a risk factor for non-adherence and lack of suppression in HIV infection. J Acquir Immune Defic Syndr. 2006;43(4):411–7.PubMedPubMedCentralCrossRef
14.
go back to reference Wardell J, Shuper P, Rourke S, Hendershot C. Stigma, coping, and alcohol use severity among people living with HIV: a prospective analysis of bidirectional and mediated associations. Ann Behav Med. 2018;52:762–72.PubMedPubMedCentralCrossRef Wardell J, Shuper P, Rourke S, Hendershot C. Stigma, coping, and alcohol use severity among people living with HIV: a prospective analysis of bidirectional and mediated associations. Ann Behav Med. 2018;52:762–72.PubMedPubMedCentralCrossRef
15.
go back to reference Blashill AJ, Perry N, Safren SA. Mental health: a focus on stress, coping, and mental illness as it relates to treatment retention, adherence and other health outcomes. Curr HIV/AIDS Rep. 2011;8(4):215–22.PubMedPubMedCentralCrossRef Blashill AJ, Perry N, Safren SA. Mental health: a focus on stress, coping, and mental illness as it relates to treatment retention, adherence and other health outcomes. Curr HIV/AIDS Rep. 2011;8(4):215–22.PubMedPubMedCentralCrossRef
16.
17.
go back to reference Earnshaw V, Smith L, Chaudoir S, Amico KR, Copenhaver M. HIV stigma mechanisms and well-being among PLWH: a test of the HIV stigma framework. AIDS Behav. 2013;17(5):1785–95.PubMedPubMedCentralCrossRef Earnshaw V, Smith L, Chaudoir S, Amico KR, Copenhaver M. HIV stigma mechanisms and well-being among PLWH: a test of the HIV stigma framework. AIDS Behav. 2013;17(5):1785–95.PubMedPubMedCentralCrossRef
18.
go back to reference Turan B, Budhwani H, Pariya FL, et al. How does stigma affect people living with HIV? The mediating roles of internalizzed and anticipated HIV stigma in the effects of perceived community stigma on health and psychosocial. AIDS Behav. 2017;21:283–91.PubMedPubMedCentralCrossRef Turan B, Budhwani H, Pariya FL, et al. How does stigma affect people living with HIV? The mediating roles of internalizzed and anticipated HIV stigma in the effects of perceived community stigma on health and psychosocial. AIDS Behav. 2017;21:283–91.PubMedPubMedCentralCrossRef
19.
go back to reference Charles B, Jayaseelan L, Pandian AK, Sam AE, Thenmozhi M, et al. Association between stigma, depression and quality of life of people living with HIV/AIDS (PLHA) in South India - a community based cross sectional study. BMC Public Health. 2012;12:463. Charles B, Jayaseelan L, Pandian AK, Sam AE, Thenmozhi M, et al. Association between stigma, depression and quality of life of people living with HIV/AIDS (PLHA) in South India - a community based cross sectional study. BMC Public Health. 2012;12:463.
20.
go back to reference Simbayi L, Strebel A, Cloete A, Henda N, Mqeketo A. Internalized stigma, discrimination, and depression among men and women living with HIV/AIDS in Cape Town, South Africa. Soc Sci Med. 2007;64(9):1823–31.PubMedPubMedCentralCrossRef Simbayi L, Strebel A, Cloete A, Henda N, Mqeketo A. Internalized stigma, discrimination, and depression among men and women living with HIV/AIDS in Cape Town, South Africa. Soc Sci Med. 2007;64(9):1823–31.PubMedPubMedCentralCrossRef
21.
22.
23.
24.
go back to reference Pellowski JA, Kalichman SC, Matthews KA, Adler N. A pandemic of the poor: social disadvantage and the US HIV epidemic. Am Psychol. 2013;68(4):197–209.PubMedPubMedCentralCrossRef Pellowski JA, Kalichman SC, Matthews KA, Adler N. A pandemic of the poor: social disadvantage and the US HIV epidemic. Am Psychol. 2013;68(4):197–209.PubMedPubMedCentralCrossRef
25.
go back to reference Gant Z, Lomotey M, Hall H, Hu X, Guo X, et al. A county-level examination of the relationship between HIV and social determinants of health: 40 states, 2006–2008. Open AIDS J. 2012;6(1):1–7. Gant Z, Lomotey M, Hall H, Hu X, Guo X, et al. A county-level examination of the relationship between HIV and social determinants of health: 40 states, 2006–2008. Open AIDS J. 2012;6(1):1–7.
26.
go back to reference Ironson G, Stuetzle R, Fletcher M. An increase in religiousness/spirituality occurs after HIV diagnosis and predicts slower disease progression over 4 years in people with HIV. J Gen Intern Med. 2006;21(supplement 5):S62–8.PubMedPubMedCentralCrossRef Ironson G, Stuetzle R, Fletcher M. An increase in religiousness/spirituality occurs after HIV diagnosis and predicts slower disease progression over 4 years in people with HIV. J Gen Intern Med. 2006;21(supplement 5):S62–8.PubMedPubMedCentralCrossRef
27.
go back to reference Lesesrman J. HIV disease progression: depression, stress, and possible mechanisms. Biol Psychiatry. 2003;54(3):295–306.CrossRef Lesesrman J. HIV disease progression: depression, stress, and possible mechanisms. Biol Psychiatry. 2003;54(3):295–306.CrossRef
28.
go back to reference Lesesrman J, Petitto JM, Golden RN, et al. Impact of stressful life events, depression, social support, coping, and cortisol on progression to AIDS. Am J Psychiatriy. 2000;157(8):1221–8.CrossRef Lesesrman J, Petitto JM, Golden RN, et al. Impact of stressful life events, depression, social support, coping, and cortisol on progression to AIDS. Am J Psychiatriy. 2000;157(8):1221–8.CrossRef
29.
go back to reference Latikn CA, Curry AD. Stressful neighborhoods and depression: a prospective study of the impact of neighborhood disorder. J Health Soc Behav. 2003;44(1):34–44.CrossRef Latikn CA, Curry AD. Stressful neighborhoods and depression: a prospective study of the impact of neighborhood disorder. J Health Soc Behav. 2003;44(1):34–44.CrossRef
30.
go back to reference Latkin C, Curry A, Hua W, Davey M. Direct and indirect associations of neighborhood disorder with drug-use and high-risk sexual partners. Am J Prev Med. 2007;32(6 Suppl):S234–41.PubMedPubMedCentralCrossRef Latkin C, Curry A, Hua W, Davey M. Direct and indirect associations of neighborhood disorder with drug-use and high-risk sexual partners. Am J Prev Med. 2007;32(6 Suppl):S234–41.PubMedPubMedCentralCrossRef
31.
go back to reference Welsh D, Ferguson T, Theall K, et al. The New Orleans alcohol use in HIV [NOAH] study: a translational investigation of alcohol use, biological and socioenvironmental mechanisms, and geriatric multi-morbidity in people living with HIV. Alcohol Clin Exp Res. 2019;43(4):704–9.PubMedCrossRefPubMedCentral Welsh D, Ferguson T, Theall K, et al. The New Orleans alcohol use in HIV [NOAH] study: a translational investigation of alcohol use, biological and socioenvironmental mechanisms, and geriatric multi-morbidity in people living with HIV. Alcohol Clin Exp Res. 2019;43(4):704–9.PubMedCrossRefPubMedCentral
33.
go back to reference Lowe K. Environmental justice and pedestrianism: sidewalk continuity, race, and poverty in New Orleans, Louisiama. Transp Res Rec. 2016;2598(1):119–23.CrossRef Lowe K. Environmental justice and pedestrianism: sidewalk continuity, race, and poverty in New Orleans, Louisiama. Transp Res Rec. 2016;2598(1):119–23.CrossRef
34.
go back to reference Wellford C, Bond BJ, Goodison S. Crime in New Orleans: analyzing crime trends and New Orleans’ responses to crime. In: Justice USDo, editor. . Baltimore: University of Maryland; 2011. Wellford C, Bond BJ, Goodison S. Crime in New Orleans: analyzing crime trends and New Orleans’ responses to crime. In: Justice USDo, editor. . Baltimore: University of Maryland; 2011.
35.
go back to reference Kegler S, Dahlberg L, Mercy J. Firearm homicides and suicides in major metropolitan areas, 2012–2013 and 2015–2016. MMWR Morb Mortal Wkly Rep. 2018; 67(44):1233–1237. Kegler S, Dahlberg L, Mercy J. Firearm homicides and suicides in major metropolitan areas, 2012–2013 and 2015–2016. MMWR Morb Mortal Wkly Rep. 2018; 67(44):1233–1237.
36.
go back to reference Berger B, Ferrans C, Lashley R. Measuring stigma in people with HIV: psychometric assessment of the HIV stigma scale. Res Nurs Health. 2001;24:518–29.PubMedCrossRef Berger B, Ferrans C, Lashley R. Measuring stigma in people with HIV: psychometric assessment of the HIV stigma scale. Res Nurs Health. 2001;24:518–29.PubMedCrossRef
37.
go back to reference Saunders JB, Aasland OG, Babor TF, de la Fuente JR, Grant M. Development of the alcohol use disorders identification test (AUDIT): WHO collaborative project on early detection of person with harmful consumption—II. Addiction. 1993;88(6):791–804.PubMedCrossRef Saunders JB, Aasland OG, Babor TF, de la Fuente JR, Grant M. Development of the alcohol use disorders identification test (AUDIT): WHO collaborative project on early detection of person with harmful consumption—II. Addiction. 1993;88(6):791–804.PubMedCrossRef
38.
go back to reference Bohn MJ, Babor TF, Kranzler HR. The alcohol-use disorders identification test (Audit) - validation of a screening instrument for use in medical settings. J Stud Alcohol. 1995;56(4):423–32.PubMedCrossRef Bohn MJ, Babor TF, Kranzler HR. The alcohol-use disorders identification test (Audit) - validation of a screening instrument for use in medical settings. J Stud Alcohol. 1995;56(4):423–32.PubMedCrossRef
39.
go back to reference Valladolid GR, Vicedo JB, Sanchez-Serrano MCC, Carrasco JSD. Validation of the alcohol use disorders identification test (AUDIT) in primary care. Rev Clin Esp. 1998;198(1):11–4. Valladolid GR, Vicedo JB, Sanchez-Serrano MCC, Carrasco JSD. Validation of the alcohol use disorders identification test (AUDIT) in primary care. Rev Clin Esp. 1998;198(1):11–4.
40.
go back to reference Tang YL, Jovanovic T, Wingo A, Michopoulos V, Schwartz A, Ressler KJ. Validation of the alcohol use disorders identification test (AUDIT) in an inner city primary care Sample. Biol Psychiatry. 2015;77(9):374s–374s. Tang YL, Jovanovic T, Wingo A, Michopoulos V, Schwartz A, Ressler KJ. Validation of the alcohol use disorders identification test (AUDIT) in an inner city primary care Sample. Biol Psychiatry. 2015;77(9):374s–374s.
41.
go back to reference Lundin A, Hallgren M, Balliu N, Forsell Y. The use of alcohol use disorders identification test (AUDIT) in detecting alcohol use disorder and risk drinking in the general population: validation of AUDIT using schedules for clinical assessment in neuropsychiatry. Alcohol Clin Exp Res. 2015;39(1):158–65.PubMedCrossRef Lundin A, Hallgren M, Balliu N, Forsell Y. The use of alcohol use disorders identification test (AUDIT) in detecting alcohol use disorder and risk drinking in the general population: validation of AUDIT using schedules for clinical assessment in neuropsychiatry. Alcohol Clin Exp Res. 2015;39(1):158–65.PubMedCrossRef
42.
go back to reference Zigmond AS, Snaith RP. The hospital anxiety and depression scale. Acta Psychiatr Scand. 1983;67(6):361–70.PubMedCrossRef Zigmond AS, Snaith RP. The hospital anxiety and depression scale. Acta Psychiatr Scand. 1983;67(6):361–70.PubMedCrossRef
44.
go back to reference Bjelland I, Dahl AA, Haug TT, Neckelmann D. The validity of the hospital anxiety and depression scale. An updated literature review. J Psychosom Res. 2002;52(2):69–77.CrossRefPubMed Bjelland I, Dahl AA, Haug TT, Neckelmann D. The validity of the hospital anxiety and depression scale. An updated literature review. J Psychosom Res. 2002;52(2):69–77.CrossRefPubMed
46.
go back to reference Jaffee KD, Liu GC, Canty-Mitchell J, Qi RA, Austin J, Swigonski N. Race, Urban community stressors, and behavioral and emotional problems of children with special health care needs. Psychiatr Serv. 2005;56:63–39.PubMedCrossRef Jaffee KD, Liu GC, Canty-Mitchell J, Qi RA, Austin J, Swigonski N. Race, Urban community stressors, and behavioral and emotional problems of children with special health care needs. Psychiatr Serv. 2005;56:63–39.PubMedCrossRef
47.
go back to reference McNutt LA, Wu C, Xuer X, Hafner JP. Estimating relative risk in cohort studies and clinical trials of common outcomes. Am J Epidemiol. 2003;157(10):940–3 McNutt LA, Wu C, Xuer X, Hafner JP. Estimating relative risk in cohort studies and clinical trials of common outcomes. Am J Epidemiol. 2003;157(10):940–3
48.
go back to reference Yelland LN, Salter AB, Ryan P. Performance of the modified Poisson regression approach for estimating relative risks from clustered prospective data. Am J Epidemiol. 2011;174(8):984–92.PubMedCrossRef Yelland LN, Salter AB, Ryan P. Performance of the modified Poisson regression approach for estimating relative risks from clustered prospective data. Am J Epidemiol. 2011;174(8):984–92.PubMedCrossRef
49.
go back to reference Katz I, Ryu A, Onuegbu, Psaros C, Weiser SD, et al. Impact of HIV-related stigma on treatment adherence: systematic and meta-synthesis. J Int AIDS Soc. 2013;16;(3 Suppl 2):18640. Katz I, Ryu A, Onuegbu, Psaros C, Weiser SD, et al. Impact of HIV-related stigma on treatment adherence: systematic and meta-synthesis. J Int AIDS Soc. 2013;16;(3 Suppl 2):18640.
50.
go back to reference Bowleg L. The problem with the phrase women and minorities: intersectionality—an important theoretical framework for public health. Am J Public Health. 2012;102(7):1267–73.PubMedPubMedCentralCrossRef Bowleg L. The problem with the phrase women and minorities: intersectionality—an important theoretical framework for public health. Am J Public Health. 2012;102(7):1267–73.PubMedPubMedCentralCrossRef
51.
go back to reference Apinundecha C, Laohasiriwong W, Cameron MP, Lim S. A community participation intervention to reduce HIV/AIDS stigma, Nakhon Ratchasima province, Northeast Thailand. AIDS Care. 2007;19(9):1157–65.PubMedCrossRef Apinundecha C, Laohasiriwong W, Cameron MP, Lim S. A community participation intervention to reduce HIV/AIDS stigma, Nakhon Ratchasima province, Northeast Thailand. AIDS Care. 2007;19(9):1157–65.PubMedCrossRef
52.
go back to reference Wolitski R, Kidder D, Pals S, Royal S, Aidala A, et al. Randomized trial of the effects of housing assistance on the health and risk behaviors of homeless and unstably housed people living with HIV. AIDS Behav. 2010;14(3):493–503.PubMedCrossRef Wolitski R, Kidder D, Pals S, Royal S, Aidala A, et al. Randomized trial of the effects of housing assistance on the health and risk behaviors of homeless and unstably housed people living with HIV. AIDS Behav. 2010;14(3):493–503.PubMedCrossRef
Metadata
Title
HIV Stigma, Mental Health, and Alcohol Use Disorders among People Living with HIV/AIDS in New Orleans
Authors
Erica A. Felker-Kantor
Maeve E. Wallace
Aubrey Spriggs Madkour
Dustin T. Duncan
Katherine Andrinopoulos
Katherine Theall
Publication date
01-12-2019
Publisher
Springer US
Published in
Journal of Urban Health / Issue 6/2019
Print ISSN: 1099-3460
Electronic ISSN: 1468-2869
DOI
https://doi.org/10.1007/s11524-019-00390-0

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